Items where Funder is British Heart Foundation.
086998/Z/08/Z
Walton, RD, Jones, SA, Rostron, KA et al. (4 more authors) (2016) Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 71 (8). pp. 1005-1013. ISSN 1079-5006
088908/Z/09/Z
Zakkaroff, C, Biglands, JD, Greenwood, JP et al. (4 more authors) (2016) Investigation into diagnostic accuracy of common strategies for automated perfusion motion correction. Journal of Medical Imaging, 3 (2). 024002. ISSN 2329-4302
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
093072/Z/10/Z
Lall, VK, Bruce, G, Voytenko, L et al. (5 more authors) (2017) Physiologic regulation of heart rate and blood pressure involves connexin 36-containing gap junctions. FASEB Journal, 31 (9). pp. 3966-3977. ISSN 0892-6638
094232/Z/10/Z
Haywood, NJ, Wolny, M, Rogers, B et al. (4 more authors) (2016) Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation. Biochemical Journal, 473 (16). pp. 2485-2493. ISSN 0264-6021
104918/Z/14/Z
Fozzato, A., New, L.E., Griffiths, J.C. et al. (3 more authors) (2023) Manipulating mitochondrial dynamics in the NTS prevents diet-induced deficits in brown fat morphology and glucose uptake. Life Sciences, 328. 121922. ISSN 0024-3205
Parker, F, Batchelor, M orcid.org/0000-0001-6338-5698, Wolny, M et al. (3 more authors) (2018) A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo. Journal of Molecular Biology, 430 (10). pp. 1459-1478. ISSN 0022-2836
105586/Z/14/Z
Eyre, B. orcid.org/0000-0001-9261-3776, Shaw, K., Sharp, P. et al. (5 more authors) (2022) The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice. Scientific Reports, 12. 6236. ISSN 2045-2322
Eyre, B. orcid.org/0000-0001-9261-3776, Shaw, K., Sharp, P. et al. (5 more authors) (2022) The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice. Scientific Reports, 12. 6236. ISSN 2045-2322
Chhabria, K., Vouros, A., Gray, C. et al. (7 more authors) (2019) Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish. Disease Models and Mechanisms, 12 (9). ISSN 1754-8403
109294/Z/15/Z
Hauser, JR, Beard, HA, Bayana, ME et al. (3 more authors) (2016) Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole. Beilstein Journal of Organic Chemistry, 12. pp. 2019-2025. ISSN 1860-5397
110044/Z/15/Z
Beech, DJ and Kalli, AC orcid.org/0000-0001-7156-9403 (2019) Force Sensing by Piezo Channels in Cardiovascular Health and Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 39 (11). pp. 2228-2239. ISSN 1079-5642
Baradaran-Heravi, A, Bauer, CC, Pickles, IB et al. (7 more authors) (2022) Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. Journal of Biological Chemistry, 298 (2). 101546. p. 101546. ISSN 0021-9258
Shi, J orcid.org/0000-0003-2179-8579, Hyman, AJ orcid.org/0000-0003-0874-6678, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
Morley, LC, Debant, M, Walker, JJ et al. (2 more authors) (2021) Placental blood flow sensing and regulation in fetal growth restriction. Placenta, 113. pp. 23-28. ISSN 0143-4004
Cheng, CW orcid.org/0000-0002-2873-0828, Deivasikamani, V, Ludlow, MJ et al. (4 more authors) (2020) Genetic variants of PIEZO1 associate with COVID-19 fatality. [Preprint]
Parsonage, G, Cuthbertson, K, Endesh, N et al. (16 more authors) (2023) Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British Journal of Pharmacology, 180 (16). pp. 2039-2063. ISSN 0007-1188
Endesh, N., Chuntharpursat-Bon, E., Revill, C. et al. (11 more authors) (2023) Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver International, 43 (9). pp. 2026-2038. ISSN 1478-3223
Lichtenstein, L. orcid.org/0000-0003-3900-786X, Cheng, C., Evans, E. et al. (12 more authors) (2024) Lipid regulatory effects of endothelial force sensing. In: Atherosclerosis. 92nd EAS Congress, 26-29 May 2024, Lyon, France. Elsevier .
Caolo, V, Debant, M, Endesh, N et al. (5 more authors) (2019) Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression. [Preprint]
Evans, EL, Povstyan, OV, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (9 more authors) (2020) RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of DHS. Blood. ISSN 0006-4971
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (3 more authors) (2019) Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity. [Preprint]
Kinsella, J.A., Debant, M., Parsonage, G. et al. (5 more authors) (2024) Pharmacology of PIEZO1 channels. British Journal of Pharmacology, 181 (23). pp. 4714-4732. ISSN 0007-1188
Morley, LC orcid.org/0000-0002-1109-1396, Debant, M, Gaunt, HJ et al. (2 more authors) (2023) Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies. Reproduction & Fertility, 4 (1). e220100. ISSN 2633-8386
Beech, DJ and Xiao, B (2018) Piezo channel mechanisms in health and disease. The Journal of Physiology, 596 (6). pp. 965-967. ISSN 0022-3751
Bon, RS orcid.org/0000-0003-1733-3680, Wright, DJ, Beech, DJ orcid.org/0000-0002-7683-9422 et al. (1 more author) (2022) Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine. Annual Review of Pharmacology and Toxicology, 62. pp. 427-446. ISSN 0362-1642
Lichtenstein, L. orcid.org/0000-0003-3900-786X, Cheng, C.W., Bajarwan, M. et al. (14 more authors) (2024) Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids. Science Advances, 10 (39). eadq3075. ISSN 2375-2548
Caolo, V orcid.org/0000-0001-6215-2702, Debant, M, Endesh, N et al. (6 more authors) (2020) Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. eLife, 9. ISSN 2050-084X
Morley, LC, Shi, J, Gaunt, HJ et al. (7 more authors) (2018) Piezo1 channels are mechanosensors in human fetoplacental endothelial cells. Molecular Human Reproduction, 24 (10). pp. 510-520. ISSN 1360-9947
110058/A/15/Z
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
Neale, I. orcid.org/0000-0001-7026-7390, Ali, M. orcid.org/0000-0003-0170-7182, Kronsteiner, B. orcid.org/0000-0003-0867-2867 et al. (26 more authors) (2023) CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study. mBio, 14 (5). e0121223. ISSN 2161-2129
14/0005006
Kearney, KJ, Pechlivani, N orcid.org/0000-0001-5041-5763, King, R et al. (13 more authors) (2019) Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot and reduce bleeding complications. Blood, 133 (11). pp. 1233-1244. ISSN 0006-4971
14/0739
Francis, R, Chong, J, Ramlall, M et al. (21 more authors) (2021) Effect of remote ischaemic conditioning on infarct size and remodelling in ST-segment elevation myocardial infarction patients: the CONDI-2/ERIC-PPCI CMR substudy. Basic Research in Cardiology, 116 (1). 59. ISSN 0300-8428
1603HB006/PP4
Dijokaite-Guraliuc, A., Das, R., Zhou, D. et al. (44 more authors) (2023) Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Reports, 42 (4). 112271. ISSN 2211-1247
204825/Z/16/Z
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
Morley, LC, Debant, M, Walker, JJ et al. (2 more authors) (2021) Placental blood flow sensing and regulation in fetal growth restriction. Placenta, 113. pp. 23-28. ISSN 0143-4004
205188/Z/16/Z
Prapa, M., Lago-Docampo, M., Swietlik, E.M. et al. (37 more authors) (2022) First genotype-phenotype study in TBX4 syndrome : gain-of-function mutations causative for lung disease. American Journal of Respiratory and Critical Care Medicine, 206 (12). pp. 1522-1533. ISSN 1073-449X
Khassafi, F., Chelladurai, P. orcid.org/0000-0002-8258-5115, Valasarajan, C. et al. (23 more authors) (2023) Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. Nature Cardiovascular Research, 2. pp. 917-936. ISSN 2731-0590
206632/Z/17/Z
Alandejani, F., Hameed, A., Tubman, E. et al. (20 more authors) (2022) Imaging and risk stratification in pulmonary arterial hypertension : time to include right ventricular assessment. Frontiers in Cardiovascular Medicine, 9. 797561.
207726/Z/17/Z
Straw, S orcid.org/0000-0002-2942-4574, Cole, CA, McGinlay, M et al. (9 more authors) (2023) Guideline-directed medical therapy is similarly effective in heart failure with mildly reduced ejection fraction. Clinical Research in Cardiology, 112 (1). pp. 111-122. ISSN 1861-0684
Jex, N, Chowdhary, A, Thirunavukarasu, S et al. (13 more authors) (2022) Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy. Diabetes Care, 45 (8). pp. 1852-1862. ISSN 0149-5992
212183/Z/18/Z
Howard, J.P., Wood, F.A., Finegold, J.A. et al. (12 more authors) (2021) Side effect patterns in a crossover trial of statin, placebo, and no treatment. Journal of the American College of Cardiology, 78 (12). pp. 1210-1222. ISSN 0735-1097
214567/Z/18/Z
Gosling, R.C. orcid.org/0000-0001-7465-3563, Gunn, E., Wei, H.L. orcid.org/0000-0002-4704-7346 et al. (7 more authors) (2022) Incorporating clinical parameters to improve the accuracy of angiography-derived computed fractional flow reserve. European Heart Journal - Digital Health, 3 (3). pp. 481-488. ISSN 2634-3916
Ghobrial, M. orcid.org/0000-0002-3174-653X, Haley, H., Gosling, R. et al. (29 more authors) (2024) Modelled impact of virtual fractional flow reserve in patients undergoing coronary angiography (VIRTU-4). Heart, 110 (16). pp. 1048-1055. ISSN 1355-6037
Pederzani, G., Czechowicz, K., Ghorab, N. et al. (5 more authors) (2022) The use of digital coronary phantoms for the validation of arterial geometry reconstruction and computation of virtual FFR. Fluids, 7 (6). 201. ISSN 2311-5521
215799/Z/19/Z
Swietlik, EM, Greene, D, Zhu, N et al. (56 more authors) (2021) Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 14 (1). pp. 57-70. ISSN 2574-8300
219536/Z/19/Z
Moulin, K., Stoeck, C.T. orcid.org/0000-0001-8670-0929, Axel, L. et al. (15 more authors) (2023) In Vivo Cardiac Diffusion Imaging Without Motion-Compensation Leads to Unreasonably High Diffusivity. Journal of Magnetic Resonance Imaging, 58 (6). pp. 1990-1991. ISSN 1053-1807
Teh, I orcid.org/0000-0002-6705-3129, Shelley, D, Boyle, JH et al. (10 more authors) (2023) Cardiac q-space trajectory imaging by motion-compensated tensor-valued diffusion encoding in human heart in vivo. Magnetic Resonance in Medicine, 90 (1). pp. 150-165. ISSN 0740-3194
221690/Z/20/Z
Jex, N, Chowdhary, A, Thirunavukarasu, S et al. (13 more authors) (2022) Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy. Diabetes Care, 45 (8). pp. 1852-1862. ISSN 0149-5992
29062
Foley, JRJ, Broadbent, DA, Fent, GJ et al. (8 more authors) (2019) Clinical evaluation of two dark blood methods of late gadolinium quantification of ischemic scar. Journal of magnetic resonance imaging : JMRI, 50 (1). pp. 146-152. ISSN 1053-1807
Foley, JRJ orcid.org/0000-0003-0073-1025, Everett, CC orcid.org/0000-0002-9788-840X, Cairns, D orcid.org/0000-0002-2338-0179 et al. (6 more authors) (2017) Development and external validation of a multivariable model of pre-test likelihood of coronary artery disease based on a contemporary uk population, with comparison to existing risk models. In: Heart. BCS Annual Conference, 05-07 Jun 2017, Manchester, UK. BMJ Publishing Group , A64-A66.
Foley, JRJ, Fent, GJ, Garg, P orcid.org/0000-0002-5483-169X et al. (8 more authors) (2019) Feasibility study of a single breath‐hold, 3D mDIXON pulse sequence for late gadolinium enhancement imaging of ischemic scar. Journal of Magnetic Resonance Imaging, 49 (5). pp. 1437-1445. ISSN 1053-1807
Everett, C.C., Berry, C., McCann, G.P. orcid.org/0000-0002-5542-8448 et al. (14 more authors) (2023) Randomised trial of stable chest pain investigation: 3-year clinical and quality of life results from CE-MARC 2. Open Heart, 10 (1). ARTN e002221. ISSN 2053-3624
Foley, JRJ, Fent, GJ, Garg, P et al. (8 more authors) (2018) Single breath-hold, 3d mdixon pulse sequence for late gadolinium enhancement imaging of ischaemic scar: a feasibility study. In: Heart; British Society of Cardiovascular Magnetic Resonance (BSCMR) Young Investigator Award Abstracts. BSCMR Young Investigators Award 2018, 02-04 May 2018, Edinburgh, Scotland. BMJ Publishing Group , A12-A12.
Siontis, GCM, Mavridis, D, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (5 more authors) (2018) Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials. BMJ, 360. k504. ISSN 0959-8138
Siontis, GCM, Mavridis, D, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (5 more authors) (2018) Outcomes of non-invasive diagnostic modalities for the detection of coronary artery disease: network meta-analysis of diagnostic randomised controlled trials. BMJ, 360. k504. ISSN 0959-8138
Zakkaroff, C, Biglands, JD, Greenwood, JP et al. (4 more authors) (2016) Investigation into diagnostic accuracy of common strategies for automated perfusion motion correction. Journal of Medical Imaging, 3 (2). 024002. ISSN 2329-4302
Zakkaroff, C, Biglands, JD, Greenwood, JP et al. (4 more authors) (2016) Investigation into diagnostic accuracy of common strategies for automated perfusion motion correction. Journal of Medical Imaging, 3 (2). 024002. ISSN 2329-4302
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
310747
Haywood, NJ orcid.org/0000-0002-8762-7257, Cordell, PA, Tang, KY et al. (8 more authors) (2017) Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain. Diabetes, 66 (2). pp. 287-299. ISSN 0012-1797
33808
Jones, R.J., De Bie, E.M.D.D., Groves, E. et al. (31 more authors) (2022) Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206 (1). pp. 81-93. ISSN 1073-449X
Goh, Z.M., Alabed, S. orcid.org/0000-0002-9960-7587, Shahin, Y. orcid.org/0000-0001-7425-7798 et al. (13 more authors) (2021) Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14 (6). pp. 1271-1272. ISSN 1936-878X
Lewis, R.A., Johns, C.S. orcid.org/0000-0003-3724-0430, Cogliano, M. et al. (20 more authors) (2020) Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201 (4). pp. 458-468. ISSN 1073-449X
3T92/1205
Zakkaroff, C, Biglands, JD, Greenwood, JP et al. (4 more authors) (2016) Investigation into diagnostic accuracy of common strategies for automated perfusion motion correction. Journal of Medical Imaging, 3 (2). 024002. ISSN 2329-4302
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
748369
Caolo, V orcid.org/0000-0001-6215-2702, Debant, M, Endesh, N et al. (6 more authors) (2020) Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. eLife, 9. ISSN 2050-084X
843245
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
857533
Pederzani, G., Czechowicz, K., Ghorab, N. et al. (5 more authors) (2022) The use of digital coronary phantoms for the validation of arterial geometry reconstruction and computation of virtual FFR. Fluids, 7 (6). 201. ISSN 2311-5521
9R01/14-06
Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101
9R11/1306
Zagrapan, B, Eilenberg, W, Prausmueller, S et al. (21 more authors) (2019) A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters. Thrombosis and Haemostasis, 119 (5). pp. 807-820. ISSN 0340-6245
A1026
Walmsley, R., Steele, D.S., Papaspyros, S. et al. (1 more author) (2024) Sunitinib malate induces cell death in adult human cardiac progenitor cells. Current Research in Toxicology, 6. 100167. ISSN 2666-027X
A1252
Derrick, C.J., Pollitt, E.J.G., Sevilla Uruchurtu, A.S. et al. (3 more authors) (2021) Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development, 148 (20). dev199691. ISSN 0950-1991
BB/E001831/1
Lall, VK, Bruce, G, Voytenko, L et al. (5 more authors) (2017) Physiologic regulation of heart rate and blood pressure involves connexin 36-containing gap junctions. FASEB Journal, 31 (9). pp. 3966-3977. ISSN 0892-6638
BB/I007423/1
Haywood, NJ, Wolny, M, Rogers, B et al. (4 more authors) (2016) Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation. Biochemical Journal, 473 (16). pp. 2485-2493. ISSN 0264-6021
BB/M009114/1
Cuvertino, S, Hartill, V, Colyer, A et al. (32 more authors) (2020) A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine, 22 (5). pp. 867-877. ISSN 1098-3600
BB/P007791/1
Richardson, L, Wang, D, Hughes, R et al. (2 more authors) (2022) RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Scientific Reports, 12 (1). 2841. ISSN 2045-2322
BB/P020208/1
Bauer, CC, Minard, A, Pickles, IB et al. (9 more authors) (2020) Xanthine-based photoaffinity probes allow assessment of ligand engagement by TRPC5 channels. RSC Chemical Biology. ISSN 2633-0679
Baradaran-Heravi, A, Bauer, CC, Pickles, IB et al. (7 more authors) (2022) Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. Journal of Biological Chemistry, 298 (2). 101546. p. 101546. ISSN 0021-9258
Bon, RS orcid.org/0000-0003-1733-3680, Wright, DJ, Beech, DJ orcid.org/0000-0002-7683-9422 et al. (1 more author) (2022) Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine. Annual Review of Pharmacology and Toxicology, 62. pp. 427-446. ISSN 0362-1642
BB/R013500/1
Lichtenstein, L. orcid.org/0000-0003-3900-786X, Cheng, C.W., Bajarwan, M. et al. (14 more authors) (2024) Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids. Science Advances, 10 (39). eadq3075. ISSN 2375-2548
BB/S009566/1
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
BB/S015787/1
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
BB/V014358/1
Taylor, HA orcid.org/0000-0003-3592-1857, Przemylska, L, Clavane, EM et al. (1 more author) (2022) BACE1: More than just a β‐secretase. Obesity Reviews, 23 (7). e13430. ISSN 1467-7881
Pinto, L.M., Pailas, A., Bondarchenko, M. et al. (17 more authors) (2023) DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks. Nucleic Acids Research. gkad1141. ISSN 0305-1048
Wasson, C.W., De Lorenzis, E., Clavane, E.M. et al. (14 more authors) (2024) The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis. Journal of Investigative Dermatology, 144 (10). pp. 2197-2210. ISSN 0022-202X
Meakin, PJ orcid.org/0000-0002-8553-3863, Elahi, ME, Brown, J et al. (2 more authors) (2022) The beta-secretase, BACE1, is a master regulator of vascular health. In: Acta Physiologica. Europhysiology 2022, 16-18 Sep 2022, Copenhagen. Wiley-Blackwell , p. 547.
Clavane, EM, Taylor, HA, Cubbon, RM orcid.org/0000-0001-7844-3600 et al. (1 more author) (2022) Endothelial Cell Fibrin Gel Angiogenesis Bead Assay. In: Benest, AV, (ed.) Angiogenesis: Methods and Protocols. Methods in Molecular Biology, 2441 . Springer , New York, USA , pp. 321-327. ISBN 978-1-0716-2058-8
BHF-FS/13/48/30453
Zhu, N., Swietlik, E.M., Welch, C.L. et al. (22 more authors) (2021) Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Medicine, 13 (1). p. 80. ISSN 1756-994X
BHF-FS/14/8/30605
Gomez, I., Ward, B., Souilhol, C. et al. (21 more authors) (2020) Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications, 11 (1). 214.
Lodge, K.M., Vassallo, A., Liu, B. et al. (15 more authors) (2022) Hypoxia increases the potential for neutrophil-mediated endothelial damage in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine, 205 (8). pp. 903-916. ISSN 1073-449X
BHF-FS/18/52/33808
Goh, Z.M., Alabed, S. orcid.org/0000-0002-9960-7587, Shahin, Y. orcid.org/0000-0001-7425-7798 et al. (13 more authors) (2021) Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14 (6). pp. 1271-1272. ISSN 1936-878X
Zawia, A., Arnold, N.D. orcid.org/0000-0002-4317-5738, West, L. orcid.org/0000-0003-2953-2521 et al. (9 more authors) (2021) Altered macrophage polarization induces experimental pulmonary hypertension and is observed in patients with pulmonary arterial hypertension. Arteriosclerosis, thrombosis, and vascular biology, 41 (1). pp. 430-445. ISSN 1079-5642
Kiely, D.G. orcid.org/0000-0003-0184-6502, Lawrie, A. orcid.org/0000-0003-4192-9505 and Humbert, M. (2019) Screening strategies for pulmonary arterial hypertension. European Heart Journal Supplements, 21 (Supplement_K). K9-K20. ISSN 1520-765X
Swietlik, EM, Greene, D, Zhu, N et al. (56 more authors) (2021) Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 14 (1). pp. 57-70. ISSN 2574-8300
BHF-PG/11/116/29288
Errington, N. orcid.org/0000-0001-6768-7394, Iremonger, J., Pickworth, J.A. orcid.org/0000-0002-7199-364X et al. (13 more authors) (2021) A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine, 69. 103444. ISSN 2352-3964
BHF-PG/13/55/30365
Eyre, B. orcid.org/0000-0001-9261-3776, Shaw, K., Sharp, P. et al. (5 more authors) (2022) The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice. Scientific Reports, 12. 6236. ISSN 2045-2322
Pinteaux, E., Abdulaal, W.H., Mufazalov, I.A. et al. (5 more authors) (2020) Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors : a new toolbox to study the role of IL-1 in health and disease. Journal of Molecular Medicine, 98 (7). pp. 923-930. ISSN 0946-2716
Tulotta, C., Lefley, D.V., Moore, C.K. et al. (13 more authors) (2021) IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. npj Breast Cancer, 7 (1). 95.
BHF-PG/14/38/30862
Gomez, I., Ward, B., Souilhol, C. et al. (21 more authors) (2020) Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications, 11 (1). 214.
Dow, R. and Ridger, V. orcid.org/0000-0003-4163-669X (2021) Neutrophil microvesicles and their role in disease. The International Journal of Biochemistry & Cell Biology, 141. 106097. ISSN 1357-2725
BHF-RG/13/1/30042
An, W., Luong, L.A., Bowden, N.P. et al. (12 more authors) (2022) Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling. Cardiovascular Research, 118 (2). pp. 638-653. ISSN 0008-6363
BHF-RG/19/10/34506
Davidson, S.M., Padró, T., Bollini, S. et al. (8 more authors) (2021) Progress in cardiac research : from rebooting cardiac regeneration to a complete cell atlas of the heart. Cardiovascular Research, 117 (10). pp. 2161-2174. ISSN 0008-6363
BHF-TG/19/1/34451
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
CC/22/250026
Nadarajah, R., Wahab, A., Reynolds, C. et al. (10 more authors) (2023) Future Innovations in Novel Detection for Atrial Fibrillation (FIND-AF): pilot study of an electronic health record machine learning algorithm-guided intervention to identify undiagnosed atrial fibrillation. Open Heart, 10 (2). e002447. ISSN 2053-3624
Nadarajah, R orcid.org/0000-0001-9895-9356, Wu, J, Hogg, DC et al. (10 more authors) (2023) Prediction of short-term atrial fibrillation risk using primary care electronic health records. Heart. ISSN 1355-6037
CDCE/TA/20/910009
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
CH/13/1/30086
Viswambharan, VH orcid.org/0000-0002-7616-5026, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Sengupta, A et al. (18 more authors) (2017) Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop. Circulation Research, 120 (5). pp. 784-798. ISSN 0009-7330
Mercer, BN, Walker, AMN, Warmke, N orcid.org/0000-0001-8037-2186 et al. (10 more authors) (2016) Systemic insulin resistance without dysglycaemia impairs angiogenesis. In: Heart. BSCR Autumn 2016 - Cardiovascular Disease and Diabetes, 05-06 Sep 2016, Leeds, UK. BMJ Publishing Group , A1-A1.
Brown, O.I., Bridge, K.I., Straw, S. et al. (13 more authors) (2024) Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue. Journal of Visualized Experiments, 206. e66608. ISSN 1940-087X
CH/16/2/32089
Saunderson, CED, Paton, MF, Chowdhary, A et al. (15 more authors) (2020) Feasibility and validation of trans-valvular flow derived by four-dimensional flow cardiovascular magnetic resonance imaging in pacemaker recipients. Magnetic Resonance Imaging, 74. pp. 46-55. ISSN 0730-725X
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
COV-LT2-0049
Grist, J.T., Collier, G.J. orcid.org/0000-0002-1874-4775, Walters, H. et al. (17 more authors) (2022) Lung abnormalities depicted with hyperpolarized Xenon MRI in patients with Long COVID. Radiology. 220069. ISSN 0033-8419
CS/16/2/32145
Gale, CP orcid.org/0000-0003-4732-382X, Stocken, DD, Aktaa, S et al. (10 more authors) (2023) Effectiveness of GRACE risk score in patients admitted to hospital with non-ST elevation acute coronary syndrome (UKGRIS): parallel group cluster randomised controlled trial. BMJ: British Medical Journal, 381. e073843. ISSN 1759-2151
Everett, CC orcid.org/0000-0002-9788-840X, Fox, KAA, Reynolds, C et al. (10 more authors) (2019) Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial. BMJ Open, 9 (9). ARTN: 0321. ISSN 2044-6055
CTF-2014-03-03
Wu, J orcid.org/0000-0001-6093-599X, Gale, CP orcid.org/0000-0003-4732-382X, Hall, M orcid.org/0000-0003-1246-2627 et al. (7 more authors) (2018) Impact of initial hospital diagnosis on mortality for acute myocardial infarction: A national cohort study. European Heart Journal: Acute Cardiovascular Care, 7 (2). pp. 139-148. ISSN 2048-8726
EP/H00453X/1
Gosling, R.C. orcid.org/0000-0001-7465-3563, Gunn, E., Wei, H.L. orcid.org/0000-0002-4704-7346 et al. (7 more authors) (2022) Incorporating clinical parameters to improve the accuracy of angiography-derived computed fractional flow reserve. European Heart Journal - Digital Health, 3 (3). pp. 481-488. ISSN 2634-3916
EP/I011056/1
Gosling, R.C. orcid.org/0000-0001-7465-3563, Gunn, E., Wei, H.L. orcid.org/0000-0002-4704-7346 et al. (7 more authors) (2022) Incorporating clinical parameters to improve the accuracy of angiography-derived computed fractional flow reserve. European Heart Journal - Digital Health, 3 (3). pp. 481-488. ISSN 2634-3916
EP/J010731/1
Hauser, JR, Beard, HA, Bayana, ME et al. (3 more authors) (2016) Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole. Beilstein Journal of Organic Chemistry, 12. pp. 2019-2025. ISSN 1860-5397
EX470375
Walton, RD, Jones, SA, Rostron, KA et al. (4 more authors) (2016) Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 71 (8). pp. 1005-1013. ISSN 1079-5006
FA/13/23/30122
Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101
FS/06/085/21961
Aziz, A, Haywood, NJ orcid.org/0000-0002-8762-7257, Cordell, PA et al. (11 more authors) (2018) Insulinlike Growth Factor-Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance. Endocrinology, 159 (2). pp. 696-709. ISSN 0013-7227
FS/10/062/28409
Garg, P orcid.org/0000-0002-5483-169X, Broadbent, DA, Swoboda, PP orcid.org/0000-0001-7162-7079 et al. (12 more authors) (2017) Acute Infarct Extracellular Volume Mapping to Quantify Myocardial Area at Risk and Chronic Infarct Size on Cardiovascular Magnetic Resonance Imaging. Circulation: Cardiovascular Imaging, 10. e006182. ISSN 1941-9651
Begg, GA orcid.org/0000-0001-5260-4293, Holden, AV, Lip, GYH et al. (2 more authors) (2016) Assessment of atrial fibrosis for the rhythm control of atrial fibrillation. International Journal of Cardiology, 220. pp. 155-161. ISSN 0167-5273
Begg, GA orcid.org/0000-0001-5260-4293, Lip, GYL, Plein, S et al. (1 more author) (2017) Circulating biomarkers of fibrosis and cardioversion of atrial fibrillation: A prospective, controlled cohort study. Clinical Biochemistry, 50 (1-2). pp. 11-15. ISSN 0009-9120
Crandon, S, Elbaz, MSM, Westenberg, JJM et al. (3 more authors) (2017) Clinical applications of intra-cardiac four-dimensional flow cardiovascular magnetic resonance: A systematic review. International Journal of Cardiology, 249. pp. 486-493. ISSN 0167-5273
Garg, P orcid.org/0000-0002-5483-169X, Westenberg, JJM, van den Boogaard, PJ et al. (11 more authors) (2018) Comparison of Fast Acquisition Strategies in Whole-Heart Four-Dimensional Flow Cardiac MR: Two-center, 1.5 Tesla, Phantom and In-vivo Validation Study. Journal of Magnetic Resonance Imaging, 47 (1). pp. 272-281. ISSN 1053-1807
Begg, GA orcid.org/0000-0001-5260-4293, Karim, R, Oesterlein, T et al. (9 more authors) (2018) Left atrial voltage, circulating biomarkers of fibrosis, and atrial fibrillation ablation. A prospective cohort study. PLoS ONE, 13 (1). e0189936. ISSN 1932-6203
Swoboda, PPL, McDiarmid, AK, Erhayiem, B et al. (7 more authors) (2016) Assessing Myocardial Extracellular Volume by T1 Mapping to Distinguish Hypertrophic Cardiomyopathy From Athlete’s Heart. Journal of the American College of Cardiology, 67 (18). pp. 2189-2190. ISSN 0735-1097
Swoboda, PP orcid.org/0000-0001-7162-7079, Erhayiem, B, McDiarmid, AK et al. (9 more authors) (2016) Relationship between cardiac deformation parameters measured by cardiovascular magnetic resonance and aerobic fitness in endurance athletes. Journal of Cardiovascular Magnetic Resonance, 18. 48. ISSN 1097-6647
McDiarmid, AK, Swoboda, PP orcid.org/0000-0001-7162-7079, Erhayiem, B et al. (10 more authors) (2016) Athletic Cardiac Adaptation in Males Is a Consequence of Elevated Myocyte Mass. Circulation: Cardiovascular Imaging, 9 (4). e003579. ISSN 1941-9651
FS/11/44/28820611
Rashid, ST, Haywood, NJ orcid.org/0000-0002-8762-7257, Yuldasheva, NY orcid.org/0000-0001-6213-6358 et al. (5 more authors) (2018) Preservation of vascular endothelial repair in mice with diet‐induced obesity. Obesity Science and Practice, 4 (5). pp. 490-496. ISSN 2055-2238
FS/11/94/29180
Sengupta, A, Patel, PA, Yuldasheva, NY orcid.org/0000-0001-6213-6358 et al. (13 more authors) (2018) Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice. Endocrinology, 159 (8). pp. 2917-2925. ISSN 0013-7227
FS/12/20/29462
Smith, GA, Fearnley, G, Abdul Zani, I et al. (4 more authors) (2017) Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function. Biology Open, 6 (10). pp. 1404-1415. ISSN 2046-6390
Fearnley, GW, Smith, GA, Abdul Zani, I et al. (9 more authors) (2016) VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biology Open, 2016 (5). pp. 571-583. ISSN 2046-6390
Smith, GA, Fearnley, GW, Zani, IA et al. (4 more authors) (2016) VEGFR2 trafficking, signaling and proteolysis is regulated by the ubiquitin isopeptidase USP8. Traffic, 17 (1). pp. 53-65. ISSN 1398-9219
Smith, GA, Fearnley, GW, Tomlinson, DC et al. (2 more authors) (2015) The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis. Bioscience Reports, 35 (5). e00253. ISSN 0144-8463
FS/12/26/29395
Bridge, KI, Bollen, L, Zhong, J et al. (7 more authors) (2017) Thrombin-Activatable Fibrinolysis Inhibitor in Human Abdominal Aortic Aneurysm Disease. Journal of Thrombosis and Haemostasis, 15 (11). pp. 2218-2225. ISSN 1538-7933
FS/12/80/29821
Sengupta, A, Patel, PA, Yuldasheva, NY orcid.org/0000-0001-6213-6358 et al. (13 more authors) (2018) Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice. Endocrinology, 159 (8). pp. 2917-2925. ISSN 0013-7227
Walker, AMN orcid.org/0000-0003-0380-7283, Warmke, N, Mercer, B et al. (13 more authors) (2021) Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis. Endocrinology, 162 (8). bqab104. ISSN 0013-7227
Warmke, N, Platt, F, Bruns, AF et al. (11 more authors) (2021) Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling. Endocrinology. ISSN 0013-7227
Kalucka, J, Bierhansl, L, Conchinha, NV et al. (36 more authors) (2018) Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis. Cell Metabolism, 28 (6). 881-894.e13. ISSN 1550-4131
Eelen, G, Dubois, C, Cantelmo, AR et al. (36 more authors) (2018) Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature, 561 (7721). pp. 63-69. ISSN 0028-0836
Drozd, M orcid.org/0000-0003-0255-4624, Pujades-Rodriguez, M, Morgan, AW et al. (4 more authors) (2022) Systemic inflammation is associated with future risk of fatal infection: an observational cohort study. The Journal of Infectious Diseases. ISSN 0022-1899
Huang, H, Vandekeere, S, Kalucka, J et al. (17 more authors) (2017) Role of glutamine and interlinked asparagine metabolism in vessel formation. The EMBO Journal, 36 (16). pp. 2334-2352. ISSN 0261-4189
FS/12/88/29901
Swoboda, PP orcid.org/0000-0001-7162-7079, McDiarmid, AK, Erhayiem, B et al. (12 more authors) (2016) A novel and practical screening tool for the detection of silent myocardial infarction in patients with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 101 (9). pp. 3316-3323. ISSN 0021-972X
Swoboda, PPL, McDiarmid, AK, Erhayiem, B et al. (7 more authors) (2016) Assessing Myocardial Extracellular Volume by T1 Mapping to Distinguish Hypertrophic Cardiomyopathy From Athlete’s Heart. Journal of the American College of Cardiology, 67 (18). pp. 2189-2190. ISSN 0735-1097
Swoboda, PP orcid.org/0000-0001-7162-7079, Erhayiem, B, McDiarmid, AK et al. (9 more authors) (2016) Relationship between cardiac deformation parameters measured by cardiovascular magnetic resonance and aerobic fitness in endurance athletes. Journal of Cardiovascular Magnetic Resonance, 18. 48. ISSN 1097-6647
McDiarmid, AK, Swoboda, PP orcid.org/0000-0001-7162-7079, Erhayiem, B et al. (10 more authors) (2016) Athletic Cardiac Adaptation in Males Is a Consequence of Elevated Myocyte Mass. Circulation: Cardiovascular Imaging, 9 (4). e003579. ISSN 1941-9651
FS/13/32/30069
Elpidorou, M, Best, S, Poulter, JA orcid.org/0000-0003-2048-5693 et al. (4 more authors) (2020) Novel loss-of-function mutation in HERC2 is associated with severe developmental delay and paediatric lethality. Journal of Medical Genetics. ISSN 0022-2593
Cuvertino, S, Hartill, V, Colyer, A et al. (32 more authors) (2020) A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine, 22 (5). pp. 867-877. ISSN 1098-3600
Hartill, VL, Van de Hoek, G, Patel, MP et al. (25 more authors) (2018) DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human Molecular Genetics, 27 (3). pp. 529-545. ISSN 0964-6906
FS/13/38/33659
Taylor, H., Brown, J., Clavane, E. et al. (3 more authors) (2024) BS53 The role of BACE1 in metabolic dysfunction and cerebrovascular disease. In: Heart. British Cardiovascular Society Annual Conference, ‘Back to the patient’, 03-05 Jun 2024, Manchester, UK. BMJ Publishing Group , a281-a281.
Taylor, HA orcid.org/0000-0003-3592-1857, Przemylska, L, Clavane, EM et al. (1 more author) (2022) BACE1: More than just a β‐secretase. Obesity Reviews, 23 (7). e13430. ISSN 1467-7881
Pinto, L.M., Pailas, A., Bondarchenko, M. et al. (17 more authors) (2023) DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks. Nucleic Acids Research. gkad1141. ISSN 0305-1048
Wasson, C.W., De Lorenzis, E., Clavane, E.M. et al. (14 more authors) (2024) The β-Secretase BACE1 Drives Fibroblast Activation in Systemic Sclerosis through the APP/β-Catenin/Notch Signaling Axis. Journal of Investigative Dermatology, 144 (10). pp. 2197-2210. ISSN 0022-202X
Meakin, PJ orcid.org/0000-0002-8553-3863, Elahi, ME, Brown, J et al. (2 more authors) (2022) The beta-secretase, BACE1, is a master regulator of vascular health. In: Acta Physiologica. Europhysiology 2022, 16-18 Sep 2022, Copenhagen. Wiley-Blackwell , p. 547.
Meakin, PJ orcid.org/0000-0002-8553-3863, Strivens, F, Khan, F et al. (1 more author) (2019) Beta-secretase 1 (BACE1) regulates insulin sensitivity in endothelial cells. In: Diabetic Medicine. Diabetes UK Professional Conference, 06-08 Mar 2019, Liverpool, UK. Wiley , p. 71.
Meakin, PJ orcid.org/0000-0002-8553-3863, Coull, BM, Tuharska, Z et al. (16 more authors) (2020) Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction. Journal of Clinical Investigation. ISSN 0021-9738
Clavane, EM, Taylor, HA, Cubbon, RM orcid.org/0000-0001-7844-3600 et al. (1 more author) (2022) Endothelial Cell Fibrin Gel Angiogenesis Bead Assay. In: Benest, AV, (ed.) Angiogenesis: Methods and Protocols. Methods in Molecular Biology, 2441 . Springer , New York, USA , pp. 321-327. ISBN 978-1-0716-2058-8
FS/13/48/30453
Swift, A.J., Lu, H. orcid.org/0000-0002-0349-2181, Garg, P. orcid.org/0000-0002-5483-169X et al. (8 more authors) (2019) 543 A machine-learning CMR approach to extract disease features and automate pulmonary arterial hypertension diagnosis. In: European Heart Journal - Cardiovascular Imaging. EuroCMR 2019, 02-04 May 2019, Venice, Italy. Oxford University Press (OUP) .
Errington, N. orcid.org/0000-0001-6768-7394, Iremonger, J., Pickworth, J.A. orcid.org/0000-0002-7199-364X et al. (13 more authors) (2021) A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine, 69. 103444. ISSN 2352-3964
Lewis, R.A., Johns, C.S. orcid.org/0000-0003-3724-0430, Cogliano, M. et al. (20 more authors) (2020) Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201 (4). pp. 458-468. ISSN 1073-449X
FS/13/71/30378
Craven, T, Chew, PG, Gorecka, M et al. (12 more authors) (2021) 10 Primary mitral regurgitation successfully treated by percutaneous mitral valve leaflet repair results in positive cardiac reverse remodelling and functional improvement. In: British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 07-10 Jun 2021.
Craven, T, Jex, N, Gorecka, M orcid.org/0000-0002-5688-8980 et al. (11 more authors) (2021) 15 Biventricular assessment and quantification of primary mitral regurgitation is feasible and reproducible during continous supine exercise cardiovascular magnetic resonance. In: British Cardiovascular Society Virtual Annual Conference, ‘Cardiology and the Environment’, 07-10 Jun 2021.
Borlotti, A, Jerosch-Herald, M, Liu, D et al. (11 more authors) (2019) Acute Microvascular Impairment Post-Reperfused STEMI Is Reversible and Has Additional Clinical Predictive Value: A CMR OxAMI Study. JACC: Cardiovascular Imaging, 12 (9). pp. 1783-1793. ISSN 1936-878X
Das, A, Kelly, C, Ben-Arzi, H et al. (3 more authors) (2022) Acute intra-cavity 4D flow predicts long-term adverse remodelling following ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance (JCMR), 24. 64. ISSN 1097-6647
Liu, D, Borlotti, A, Viliani, D et al. (16 more authors) (2017) CMR Native T1 Mapping Allows Differentiation of Reversible Versus Irreversible Myocardial Damage in ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Imaging, 10 (8). ISSN 1941-9651
Ibanez, B, Aletras, AH, Arai, AE et al. (19 more authors) (2019) Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel. Journal of the American College of Cardiology, 74 (2). pp. 238-256. ISSN 0735-1097
Swoboda, PP, Garg, P, Foley, JR et al. (7 more authors) (2018) Cardiac effects of complete enforced detraining assessed by cardiovascular magnetic resonance. In: Heart; British Society of Cardiovascular Magnetic Resonance (BSCMR) Young Investigator Award Abstracts. BSCMR Young Investigators Award 2018, 02-04 May 2018, Edinburgh, Scotland. BMJ Publications , A10-A10.
Swoboda, PP, Garg, P, Foley, JR et al. (7 more authors) (2018) Cardiac effects of complete enforced detraining assessed by cardiovascular magnetic resonance. In: Lüscher, TF, Bax, JJ, Gersh, BJ, Landmesser, U, Matter, CM, Ruschitzka, F, Steffel, J and Wijns, W, (eds.) European Heart Journal. ESC Congress 2018, 25-29 Aug 2018, Munich, Germany. Oxford University Press , p. 1185.
Wamil, M, Borlotti, A, Liu, D et al. (12 more authors) (2019) Combined T1-mapping and tissue tracking analysis predicts severity of ischemic injury following acute STEMI—an Oxford Acute Myocardial Infarction (OxAMI) study. International Journal of Cardiovascular Imaging, 35 (7). pp. 1297-1308. ISSN 1569-5794
Villard, B, Zacur, E, Dall'Armellina, E et al. (1 more author) (2017) Correction of Slice Misalignment in Multi-breath-hold Cardiac MRI Scans. In: STACOM 2016: Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges (Lecture Notes in Computer Science ). International Workshop on Statistical Atlases and Computational Models of the Heart, 17 Oct 2016, Athens, Greece. Springer , pp. 30-38. ISBN 978-3-319-52717-8
Alkhalil, M, Borlotti, A, De Maria, GL et al. (9 more authors) (2018) Dynamic changes of injured myocardium very early after acute myocardial infarction quantified using T1 mapping cardiovascular magnetic resonance technique. In: Heart. Joint Meeting of the British-Society-of-Cardiovascular-Imaging/British-Society-of-Cardiovascular-CT, British-Society-of-Cardiovascular-Magnetic-Resonance and British-Nuclear-Cardiac-Society on British Cardiovascular Imaging, 02-04 May 2018, Edinburgh. BMJ Publishing Group , A8-A8.
Craven, TP, Jex, N, Chew, PG et al. (11 more authors) (2021) Exercise cardiovascular magnetic resonance: feasibility and development of biventricular function and great vessel flow assessment, during continuous exercise accelerated by Compressed SENSE: preliminary results in healthy volunteers. The International Journal of Cardiovascular Imaging, 37 (2). pp. 685-698. ISSN 1569-5794
Garg, P, van der Geest, RJ, Swoboda, PP et al. (17 more authors) (2018) Four-dimensional left ventricular blood flow energetics independently predict adverse remodelling post st-elevation myocardial infarction. In: Heart; British Society of Cardiovascular Magnetic Resonance (BSCMR) Young Investigator Award Abstracts. BSCMR Young Investigators Award 2018, 02-04 May 2018, Edinburgh, Scotland. BMJ Publications , A7-A7.
Dall'Armellina, E (2017) From Recognized to Novel Quantitative CMR Biomarkers of LV Recovery: A Paradigm Shift in Acute Myocardial Infarction Imaging. JACC: Cardiovascular Imaging, 10 (9). pp. 1000-1002. ISSN 1936-878X
De Maria, GL, Alkhalil, M, Wolfrum, M et al. (13 more authors) (2019) Index of Microcirculatory Resistance as a Tool to Characterize Microvascular Obstruction and to Predict Infarct Size Regression in Patients With STEMI Undergoing Primary PCI. JACC: Cardiovascular Imaging, 12 (5). pp. 837-848. ISSN 1936-878X
De Maria, GL, Alkhalil, M, Borlotti, A et al. (9 more authors) (2018) Index of microcirculatory resistance-guided therapy with pressure-controlled intermittent coronary sinus occlusion improves coronary microvascular function and reduces infarct size in patients with ST-elevation myocardial infarction: the Oxford Acute Myocardial Infarction - Pressure-controlled Intermittent Coronary Sinus Occlusion study (OxAMI-PICSO study). EuroIntervention, 14 (3). e352-e359. ISSN 1774-024X
Garg, P orcid.org/0000-0002-5483-169X, van der Geest, RJ, Swoboda, PP orcid.org/0000-0001-7162-7079 et al. (17 more authors) (2019) Left ventricular thrombus formation in myocardial infarction is associated with altered left ventricular blood flow energetics. European heart journal cardiovascular Imaging, 20 (1). pp. 108-117. ISSN 2047-2404
Das, A orcid.org/0000-0003-1134-3036, Kelly, C, Teh, I et al. (11 more authors) (2019) Longitudinal changes in diffusion tensor imaging parameters following acute ST-elevation myocardial infarction. In: EuroCMR 2019, 02-04 May 2019, Venice, Italy.
Popescu, IA, Irving, B, Borlotti, A et al. (2 more authors) (2017) Myocardial Scar Quantification Using SLIC Supervoxels - Parcellation Based on Tissue Characteristic Strains. In: STACOM 2016: Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. International Workshop on Statistical Atlases and Computational Models of the Heart, 17 Oct 2016, Athens, Greece. Springer , pp. 182-190. ISBN 978-3-319-52717-8
Herring, N, Tapoulal, N, Kalla, M et al. (13 more authors) (2019) Neuropeptide-Y causes coronary microvascular constriction and is associated with reduced ejection fraction following ST-elevation myocardial infarction. European Heart Journal, 40 (24). pp. 1920-1929. ISSN 0195-668X
Das, A, Kelly, C, Teh, I et al. (8 more authors) (2023) Pathophysiology of LV Remodeling Following STEMI: A Longitudinal Diffusion Tensor CMR Study. JACC: Cardiovascular Imaging, 16 (2). pp. 159-171. ISSN 1936-878X
Herring, N, Kalla, M, Dall'Armellina, E et al. (9 more authors) (2016) Pro-arrhythmic effects of the cardiac sympathetic co-transmitter, neuropeptide-Y, during ischemia-reperfusion and ST elevation myocardial infarction. Federation of American Societies for Experimental Biology.
Das, A, Plein, S orcid.org/0000-0002-0997-4384 and Dall'Armellina, E orcid.org/0000-0002-2165-7154 (2019) Role of CMR in Prognostic Stratification in Myocardial Infarction. Cardiorresonancia para la estratificación pronóstica del infarto de miocardio. Revista Española de Cardiología (English Edition), 72 (2). pp. 115-119. ISSN 1885-5857
Lasic, S orcid.org/0000-0002-9284-7182, Yuldasheva, N orcid.org/0000-0001-6213-6358, Szczepankiewicz, F orcid.org/0000-0002-5251-587X et al. (6 more authors) (2022) Stay on the Beat With Tensor-Valued Encoding: Time-Dependent Diffusion and Cell Size Estimation in ex vivo Heart. Frontiers in Physics, 10. 812115. ISSN 2296-424X
Roifman, I, Hammer, M, Sparkes, J et al. (3 more authors) (2022) Utilization and impact of cardiovascular magnetic resonance on patient management in heart failure: insights from the SCMR Registry. Journal of Cardiovascular Magnetic Resonance, 24. 65. ISSN 1097-6647
Sharrack, N orcid.org/0000-0001-5880-1722, Das, A, Kelly, C et al. (8 more authors) (2022) The relationship between myocardial microstructure and strain in chronic infarction using cardiac diffusion tensor imaging and feature tracking. Journal of Cardiovascular Magnetic Resonance, 24. 66. ISSN 1097-6647
Sharrack, N, Das, A, Kelly, C et al. (12 more authors) (2021) The relationship between myocardial microstructure and strain in chronic infarcts, assessed using diffusion tensor imaging and feature tracking. In: EuroCMR 2021, 06-08 May 2021, Online.
Das, A, Kelly, C, Teh, I et al. (17 more authors) (2021) Phenotyping hypertrophic cardiomyopathy using cardiac diffusion magnetic resonance imaging: the relationship between microvascular dysfunction and microstructural changes. European Heart Journal - Cardiovascular Imaging. ISSN 2047-2404
FS/14/10/30472
Walker, A.M.N., Watt, N.T., Yuldasheva, N.Y. et al. (14 more authors) (2024) Distinct, common and synergistic effects of insulin and IGF-1 receptors on healthy murine ageing. Heliyon, 10 (16). e36457. ISSN 2405-8440
Walker, AMN, Yuldasheva, N orcid.org/0000-0001-6213-6358, Sengupta, A et al. (14 more authors) (2016) Vascular repair and regeneration are improved with reduced expression of the insulin-like growth factor-1 receptor in whole body insulin resistance. In: Heart. BSCR Autumn 2016, 05-06 Sep 2016, Leeds, UK. BMJ Publishing Group , A7-A7.
FS/14/22/30734 - H Gaunt
Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (3 more authors) (2019) Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity. [Preprint]
Morley, LC orcid.org/0000-0002-1109-1396, Debant, M, Gaunt, HJ et al. (2 more authors) (2023) Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies. Reproduction & Fertility, 4 (1). e220100. ISSN 2633-8386
Evans, EL, Cuthbertson, K, Endesh, N et al. (8 more authors) (2018) Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation. British Journal of Pharmacology, 175 (10). pp. 1744-1759. ISSN 0007-1188
FS/14/41/30955
Styles, FL, Al-Owais, MM, Scragg, JL et al. (9 more authors) (2021) Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism. Cell Death & Disease, 12 (4). 372. 372-. ISSN 2041-4889
FS/15/24/31459
Stewart, L, Egnuni, T, Esteves, F et al. (3 more authors) (2018) DOCK4 genetic deletion impairs vascular recovery following an ischemic event. In: 35th Meeting of the ISHR-ES, 16-19 Jul 2018, Amsterdam.
FS/15/40/31536
Kearney, KJ, Pechlivani, N orcid.org/0000-0001-5041-5763, King, R et al. (13 more authors) (2019) Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot and reduce bleeding complications. Blood, 133 (11). pp. 1233-1244. ISSN 0006-4971
FS/15/48/31665
Blythe, NM, Muraki, K, Ludlow, MJ et al. (12 more authors) (2019) Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion. Journal of Biological Chemistry, 294 (46). pp. 17395-17408. ISSN 0021-9258
FS/16/3732347
Derrick, C.J., Pollitt, E.J.G., Sevilla Uruchurtu, A.S. et al. (3 more authors) (2021) Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development, 148 (20). dev199691. ISSN 0950-1991
FS/16/42/32308
Rode, B, Bailey, MA orcid.org/0000-0001-5038-1970, Marthan, R et al. (2 more authors) (2018) ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension. Physiology, 33 (4). pp. 261-268. ISSN 1548-9213
FS/16/48/32306
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
Gosling, R.C. orcid.org/0000-0001-7465-3563, Gunn, E., Wei, H.L. orcid.org/0000-0002-4704-7346 et al. (7 more authors) (2022) Incorporating clinical parameters to improve the accuracy of angiography-derived computed fractional flow reserve. European Heart Journal - Digital Health, 3 (3). pp. 481-488. ISSN 2634-3916
FS/17/2/32559
Wang, Y, Shi, J and Tong, X (2021) Cross-talk Between Mechanosensitive Ion Channels and Calcium Regulatory Proteins in Cardiovascular Health and Disease. International Journal of Molecular Sciences, 22 (16). 8782. ISSN 1661-6596
Wang, MJ, Zhu, YC and Shi, J (2021) A crucial physiological role of Piezo1 channel in differentiation rather than proliferation during myogenesis. Acta Physiologica, 233 (4). e13728. ISSN 1748-1708
Yaganoglu, S., Kalyviotis, K. orcid.org/0000-0002-7640-8905, Vagena-Pantoula, C. orcid.org/0000-0002-3591-2267 et al. (15 more authors) (2023) Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications, 14 (1). 4352. ISSN 2041-1723
Yaganoglu, S., Kalyviotis, K. orcid.org/0000-0002-7640-8905, Vagena-Pantoula, C. orcid.org/0000-0002-3591-2267 et al. (15 more authors) (2023) Author Correction: Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications, 14. 5787. ISSN 2041-1723
Wang, L, Yang, Z, Wang, S et al. (9 more authors) (2022) Substitution of SERCA2 Cys674 accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis. British Journal of Pharmacology, 179 (17). pp. 4423-4439. ISSN 0007-1188
Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322
Shi, J orcid.org/0000-0003-2179-8579, Hyman, AJ orcid.org/0000-0003-0874-6678, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
Morley, LC, Shi, J, Gaunt, HJ et al. (7 more authors) (2018) Piezo1 channels are mechanosensors in human fetoplacental endothelial cells. Molecular Human Reproduction, 24 (10). pp. 510-520. ISSN 1360-9947
FS/17/43/33003
Miteva, KT, Pedicini, L, Wilson, LA et al. (9 more authors) (2019) Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies. Journal of Cell Biology, 218 (7). pp. 2232-2246. ISSN 0021-9525
FS/17/66/33480
Warmke, N orcid.org/0000-0001-8037-2186, Griffin, KJ, Slater, CI et al. (3 more authors) (2017) Reduced pericyte insulin signalling causes abnormal developmental angiogenesis. In: Heart. BCS Annual Conference - Cardiology at the Extremes, 05-07 Jun 2017, Manchester, UK. BMJ Publishing Group , A127-A128.
Shawer, H, Norman, K, Cheng, CW orcid.org/0000-0002-2873-0828 et al. (3 more authors) (2021) ORAI1 Ca2+ channel as a therapeutic target in pathological vascular remodelling. Frontiers in Cell and Developmental Biology, 9. 653812. ISSN 2296-634X
Bell, M orcid.org/0000-0002-5138-0985, Gandhi, R, Shawer, H et al. (2 more authors) (2021) Imaging Biological Pathways in Abdominal Aortic Aneurysms Using Positron Emission Tomography. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (5). pp. 1596-1606. ISSN 1079-5642
FS/18/12/33270
Gandhi, R, Bell, M orcid.org/0000-0002-5138-0985, Bailey, M orcid.org/0000-0001-5038-1970 et al. (1 more author) (2021) Prospect of positron emission tomography for abdominal aortic aneurysm risk stratification. Journal of Nuclear Cardiology, 28 (5). pp. 2272-2282. ISSN 1071-3581
Gandhi, R, Bailey, MA orcid.org/0000-0001-5038-1970 and Tsoumpas, C orcid.org/0000-0002-4971-2477 (2021) Radionuclide molecular imaging of abdominal aortic aneurysms for risk stratification and non-invasive therapy assessment. Clinical and Translational Medicine, 11 (4). e386. ISSN 2001-1326
Paige, E, Clément, M, Lareyre, F et al. (22 more authors) (2019) Interleukin-6 Receptor Signalling and Abdominal Aortic Aneurysm Growth Rates. Circulation Genomics & Prescision Medicine, 12 (2). e002413. ISSN 2574-8300
Sucharitkul, PPJ, Jones, KL, Scott, DJA orcid.org/0000-0003-2894-9923 et al. (1 more author) (2021) Lipid optimisation in lower extremity peripheral arterial disease. Annals of Vascular Surgery, 76. pp. 542-554. ISSN 0890-5096
Jones, AD, Waduud, MA orcid.org/0000-0001-5567-9952, Walker, P et al. (3 more authors) (2019) Meta‐analysis of fenestrated endovascular aneurysm repair versus open surgical repair of juxtarenal abdominal aortic aneurysms over the last 10 years. British Journal of Surgery Open, 3 (5). pp. 572-584. ISSN 2474-9842
Gandhi, R orcid.org/0000-0002-9581-9312, Cawthorne, C, Craggs, LJL orcid.org/0000-0001-9192-1072 et al. (9 more authors) (2021) Cell proliferation detected using [18F]FLT PET/CT as an early marker of abdominal aortic aneurysm. Journal of Nuclear Cardiology, 28 (5). pp. 1961-1971. ISSN 1071-3581
Duff, L orcid.org/0000-0002-4295-6356, Scarsbrook, AF orcid.org/0000-0002-4243-032X, Mackie, SL orcid.org/0000-0003-2483-5873 et al. (4 more authors) (2022) A methodological framework for AI-assisted diagnosis of active aortitis using radiomic analysis of FDG PET–CT images: Initial analysis. Journal of Nuclear Cardiology, 29 (6). pp. 3315-3331. ISSN 1071-3581
Shawer, H, Norman, K, Cheng, CW orcid.org/0000-0002-2873-0828 et al. (3 more authors) (2021) ORAI1 Ca2+ channel as a therapeutic target in pathological vascular remodelling. Frontiers in Cell and Developmental Biology, 9. 653812. ISSN 2296-634X
Waduud, MA orcid.org/0000-0001-5567-9952, Kandavelu, P, Reay, M et al. (3 more authors) (2021) High-Frequency Three-Dimensional Lumen Volume Ultrasound Is a Sensitive Method to Detect Early Aneurysmal Change in Elastase-Induced Murine Abdominal Aortic Aneurysm. Aorta, 9 (6). pp. 215-220. ISSN 2325-4637
Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322
Bell, M orcid.org/0000-0002-5138-0985, Gandhi, R, Shawer, H et al. (2 more authors) (2021) Imaging Biological Pathways in Abdominal Aortic Aneurysms Using Positron Emission Tomography. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (5). pp. 1596-1606. ISSN 1079-5642
Zagrapan, B, Eilenberg, W, Prausmueller, S et al. (21 more authors) (2019) A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters. Thrombosis and Haemostasis, 119 (5). pp. 807-820. ISSN 0340-6245
FS/18/13/33281
Goh, Z.M., Alabed, S. orcid.org/0000-0002-9960-7587, Shahin, Y. orcid.org/0000-0001-7425-7798 et al. (13 more authors) (2021) Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14 (6). pp. 1271-1272. ISSN 1936-878X
Hoeper, M.M., Dwivedi, K., Pausch, C. et al. (39 more authors) (2022) Phenotyping of idiopathic pulmonary arterial hypertension : a registry analysis. The Lancet Respiratory Medicine, 10 (10). pp. 937-948. ISSN 2213-2600
Turton, H.A., Pickworth, J., Paterson, G.G. et al. (3 more authors) (2022) Soluble P-selectin and von Willebrand factor rise in healthy volunteers following non-exertional ascent to high altitude. Frontiers in Physiology, 13. 825819.
Lewis, R.A., Johns, C.S. orcid.org/0000-0003-3724-0430, Cogliano, M. et al. (20 more authors) (2020) Identification of cardiac MRI thresholds for risk stratification in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine, 201 (4). pp. 458-468. ISSN 1073-449X
Grist, J.T., Collier, G.J. orcid.org/0000-0002-1874-4775, Walters, H. et al. (17 more authors) (2022) Lung abnormalities depicted with hyperpolarized Xenon MRI in patients with Long COVID. Radiology. 220069. ISSN 0033-8419
Prapa, M., Lago-Docampo, M., Swietlik, E.M. et al. (37 more authors) (2022) First genotype-phenotype study in TBX4 syndrome : gain-of-function mutations causative for lung disease. American Journal of Respiratory and Critical Care Medicine, 206 (12). pp. 1522-1533. ISSN 1073-449X
Alandejani, F., Hameed, A., Tubman, E. et al. (20 more authors) (2022) Imaging and risk stratification in pulmonary arterial hypertension : time to include right ventricular assessment. Frontiers in Cardiovascular Medicine, 9. 797561.
FS/18/13/33281 and RG68204 13/EE/0203 A092860
Rhodes, C.J., Otero-Núñez, P., Wharton, J. et al. (28 more authors) (2020) Whole blood RNA profiles associated with pulmonary arterial hypertension and clinical outcome. American Journal of Respiratory and Critical Care Medicine, 202 (4). pp. 586-594. ISSN 1073-449X
FS/18/30/33647
Waduud, MA orcid.org/0000-0001-5567-9952, Kandavelu, P, Reay, M et al. (3 more authors) (2021) High-Frequency Three-Dimensional Lumen Volume Ultrasound Is a Sensitive Method to Detect Early Aneurysmal Change in Elastase-Induced Murine Abdominal Aortic Aneurysm. Aorta, 9 (6). pp. 215-220. ISSN 2325-4637
FS/18/44/33792
Drozd, M orcid.org/0000-0003-0255-4624, Pujades-Rodriguez, M, Morgan, AW et al. (4 more authors) (2022) Systemic inflammation is associated with future risk of fatal infection: an observational cohort study. The Journal of Infectious Diseases. ISSN 0022-1899
FS/18/49/33752
Parker, W.A.E. orcid.org/0000-0002-7822-8852, Gorog, D.A., Geisler, T. et al. (4 more authors) (2020) Prevention of stroke in patients with chronic coronary syndromes or peripheral arterial disease. European Heart Journal Supplements, 22 (Supplement_M). M26-M34. ISSN 1520-765X
FS/18/52/33808
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
Jones, R.J., De Bie, E.M.D.D., Groves, E. et al. (31 more authors) (2022) Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206 (1). pp. 81-93. ISSN 1073-449X
Hornsby, H. orcid.org/0000-0002-6657-9743, Nicols, A.R. orcid.org/0000-0002-1813-3819, Longet, S. orcid.org/0000-0001-5026-431X et al. (40 more authors) (2023) Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history. Nature Communications, 14 (1). 5065. ISSN 2041-1723
Neale, I. orcid.org/0000-0001-7026-7390, Ali, M. orcid.org/0000-0003-0170-7182, Kronsteiner, B. orcid.org/0000-0003-0867-2867 et al. (26 more authors) (2023) CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study. mBio, 14 (5). e0121223. ISSN 2161-2129
FS/18/61/34182
Deivasikamani, V, Dhayalan, S, Abudushalamu, Y et al. (12 more authors) (2019) Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific Reports, 9. 16876. ISSN 2045-2322
FS/19/41/34478
Amin, MMJ, Trevelyan, CJ and Turner, NA orcid.org/0000-0002-4957-5433 (2021) MicroRNA-214 in Health and Disease. Cells, 10 (12). 3274. ISSN 2073-4409
FS/19/45/34443
Sagar, RC, Phoenix, F, Thanabalasingham, G et al. (3 more authors) (2020) Maturity onset diabetes of the young and fibrin-related thrombosis risk. Diabetes and Vascular Disease Research, 17 (6). 1479164120963048. ISSN 1479-1641
Parker, WAE, Sagar, R, Kurdee, Z et al. (5 more authors) (2021) A randomised controlled trial to assess the antithrombotic effects of aspirin in type 1 diabetes: role of dosing and glycaemic control. Cardiovascular Diabetology, 20. 238. ISSN 1475-2840
FS/19/59/34896
Byford, A, Walsh, K, Scott, E et al. (1 more author) (2021) Temporal fluctuations in maternal glucose levels alter placental transcriptome in pregnancies complicated by gestational diabetes. In: IFPA 2021, 30 Aug - 02 Sep 2021, Virtual.
Byford, AR orcid.org/0000-0002-3936-2688, Forbes, K orcid.org/0000-0002-3745-1337 and Scott, EM orcid.org/0000-0001-5395-8261 (2022) Glucose Treatment Targets in Pregnancy - A Review of Evidence and Guidelines. Current Diabetes Reviews, 19 (2). e220422203917. ISSN 1573-3998
Byford, A., Walsh, K., Wang, D. et al. (3 more authors) (2024) Temporal Periods of Mild Hyperglycaemia in Pregnancies Complicated by GDM and LGA Impacts Pathways Associated with Hofbauer Cell Polarization and Placental Vascularisation. In: Reproductive Sciences. SRI 2024 Annual Scientifc Meeting, 12-16 Mar 2024, Vancouver, Canada. Springer , 249A-249A.
Byford, A, Walsh, K, Scott, E et al. (1 more author) (2022) Temporal periods of maternal hyperglycaemia in gestational diabetes alter placental transcriptome networks associated with inflammation and vascular development. In: SLIMP 2022, 04-06 May 2022, Online.
Kinsella, J.A., Debant, M., Parsonage, G. et al. (5 more authors) (2024) Pharmacology of PIEZO1 channels. British Journal of Pharmacology, 181 (23). pp. 4714-4732. ISSN 0007-1188
Byford, A orcid.org/0000-0002-3936-2688, Baird-Rayner, C and Forbes, K orcid.org/0000-0002-3745-1337 (2021) Don’t sugar coat it: the effects of gestational diabetes on the placental vasculature. The Biochemist, 43 (2). pp. 34-39. ISSN 0954-982X
FS/20/12/34789
Nadarajah, R orcid.org/0000-0001-9895-9356, Wu, J orcid.org/0000-0001-6093-599X, Frangi, AF orcid.org/0000-0002-2675-528X et al. (3 more authors) (2021) Predicting patient-level new-onset atrial fibrillation from population-based nationwide electronic health records: protocol of FIND-AF for developing a precision medicine prediction model using artificial intelligence. BMJ Open, 11 (11). e052887. ISSN 2044-6055
Nadarajah, R orcid.org/0000-0001-9895-9356, Alsaeed, E orcid.org/0000-0003-4161-0625, Hurdus, B orcid.org/0000-0001-8149-3449 et al. (6 more authors) (2021) Prediction of incident atrial fibrillation in community-based electronic health records: a systematic review with meta-analysis. Heart. ISSN 1355-6037
Nadarajah, R. orcid.org/0000-0001-9895-9356, Wu, J., Arbel, R. et al. (6 more authors) (2023) Risk of atrial fibrillation and association with other diseases: protocol of the derivation and international external validation of a prediction model using nationwide population-based electronic health records. BMJ Open, 13. e075196. ISSN 2044-6055
Nakao, YM, Nakao, K, Wu, J orcid.org/0000-0001-6093-599X et al. (3 more authors) (2022) Risks and benefits of oral anticoagulants for stroke prophylaxis in atrial fibrillation according to body mass index: Nationwide cohort study of primary care records in England. EClinicalMedicine, 54. 101709. ISSN 2589-5370
Wu, J orcid.org/0000-0001-6093-599X, Nadarajah, R, Nakao, YM et al. (5 more authors) (2022) Temporal trends and patterns in atrial fibrillation incidence: A population-based study of 3·4 million individuals. The Lancet Regional Health Europe, 17. 100386. ISSN 2666-7762
Nadarajah, R orcid.org/0000-0001-9895-9356, Wu, J orcid.org/0000-0001-6093-599X, Hurdus, B orcid.org/0000-0001-8149-3449 et al. (11 more authors) (2022) The collateral damage of COVID-19 to cardiovascular services: a meta-analysis. European Heart Journal, 43 (33). pp. 3164-3178. ISSN 0195-668X
Nadarajah, R orcid.org/0000-0001-9895-9356, Wu, J, Hogg, DC et al. (10 more authors) (2023) Prediction of short-term atrial fibrillation risk using primary care electronic health records. Heart. ISSN 1355-6037
FS/20/17/34730
Tardajos Ayllon, B., Bowden, N., Souilhol, C. et al. (10 more authors) (2025) Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways. Cardiovascular Research. cvaf024. ISSN 0008-6363
FS/4yPhD/F/20/34130
Owen, M.D., Quilang, R., Byford, A. et al. (13 more authors) (2024) Maternal Extracellular Vesicle Derived miR-375-3p Promotes Fetal Overgrowth in Healthy Pregnant Mice. In: Reproductive Sciences. SRI 2024 Annual Scientific Meeting, 12-16 Mar 2024, Vancouver, Canada. Springer , 57A-57A.
Owen, M.D., Kennedy, M.G., Quilang, R.C. et al. (2 more authors) (2024) The Role of microRNAs in Pregnancies Complicated by Maternal Diabetes. Clinical Science, 138 (18). pp. 1179-1207. ISSN 0143-5221
Owen, MD, Baker, BC, Scott, EM et al. (1 more author) (2021) Interaction Between Metformin, Folate and Vitamin B12 and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies. International Journal of Molecular Sciences, 22 (11). 5759. ISSN 1661-6596
FS/CRTF/20/24003
Jex, N, Chowdhary, A, Thirunavukarasu, S et al. (13 more authors) (2022) Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy. Diabetes Care, 45 (8). pp. 1852-1862. ISSN 0149-5992
FS/CRTF/20/24071
Gierula, J orcid.org/0000-0001-9588-191X, Cole, CA, Drozd, M orcid.org/0000-0003-0255-4624 et al. (18 more authors) (2022) Atrial fibrillation and risk of progressive heart failure in patients with preserved ejection fraction heart failure. ESC Heart Failure, 9 (5). pp. 3254-3263. ISSN 2055-5822
Drozd, M, Pujades-Rodriguez, M, Sun, F et al. (5 more authors) (2021) Causes of death in people with cardiovascular disease: a UK Biobank cohort study. Journal of the American Heart Association, 10 (22). e023188. ISSN 2047-9980
Malik, A, Garland, E, Drozd, M orcid.org/0000-0003-0255-4624 et al. (11 more authors) (2022) Diabetes mellitus and the causes of hospitalisation in people with heart failure. Diabetes and Vascular Disease Research, 19 (1). pp. 1-7. ISSN 1479-1641
Straw, SS, Mcginlay, M, Gierula, J orcid.org/0000-0001-9588-191X et al. (8 more authors) (2020) Early cardiac resynchronisation therapy in chronic heart failure: moving away from the linear application of guideline-directed therapy. In: European Journal of Heart Failure. HFA Discoveries, 31 Aug 2020. Wiley , p. 105.
Straw, S orcid.org/0000-0002-2942-4574, McGinlay, M, Gierula, J et al. (9 more authors) (2021) Impact of QRS duration on left ventricular remodelling and survival in patients with heart failure. Journal of Cardiovascular Medicine, 22 (11). pp. 848-856. ISSN 1558-2027
McGinlay, M, Straw, S orcid.org/0000-0002-2942-4574, Jagger, J et al. (3 more authors) (2021) Impact of the COVID-19 pandemic on the management of chronic heart failure. Reviews in Cardiovascular Medicine, 22 (2). pp. 271-276. ISSN 1530-6550
Patel, P, Nadarajah, R, Straw, S orcid.org/0000-0002-2942-4574 et al. (1 more author) (2021) Low frequency attenuation filter as a reversible cause of inappropriate shocks due to myopotential oversensing. HeartRhythm Case Reports, 7 (9). pp. 581-584. ISSN 2214-0271
McGinlay, M, Straw, S orcid.org/0000-0002-2942-4574, Byrom-Goulthorp, R et al. (5 more authors) (2021) Suboptimal Dosing of β-Blockers in Chronic Heart Failure: A Missed Opportunity? Journal of Cardiovascular Nursing. ISSN 0889-4655
Straw, S orcid.org/0000-0002-2942-4574, Baig, MW, Mishra, V et al. (6 more authors) (2022) Surgical techniques and outcomes in patients with intra-cardiac abscesses complicating infective endocarditis. Frontiers in Cardiovascular Medicine, 9. 875870. ISSN 2297-055X
Straw, S orcid.org/0000-0002-2942-4574, Cole, CA, McGinlay, M et al. (9 more authors) (2023) Guideline-directed medical therapy is similarly effective in heart failure with mildly reduced ejection fraction. Clinical Research in Cardiology, 112 (1). pp. 111-122. ISSN 1861-0684
G0900524/1
Hardy, MEL, Pervolaraki, E, Bernus, O et al. (1 more author) (2018) Dynamic Action Potential Restitution Contributes to Mechanical Restitution in Right Ventricular Myocytes From Pulmonary Hypertensive Rats. Frontiers in Physiology, 9. 205. ISSN 1664-042X
G1002076/1
Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (3 more authors) (2017) AZD1775 Induces Toxicity Through Double-Stranded DNA Breaks Independently of Chemotherapeutic Agents in p53-Mutated Colorectal Cancer Cells. Cell Cycle, 16 (22). pp. 2176-2182. ISSN 1538-4101
HEALTH-F5-2010-241955
Hartill, VL, Van de Hoek, G, Patel, MP et al. (25 more authors) (2018) DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human Molecular Genetics, 27 (3). pp. 529-545. ISSN 0964-6906
HSRYTH00 - HS00
Schneider, J orcid.org/0000-0003-0999-5684 (2023) Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution 31P-CMRS in the mouse. Journal of Cardiovascular Magnetic Resonance, 25. 6. ISSN 1097-6647
IF170011
Bell, M orcid.org/0000-0002-5138-0985, Gandhi, R, Shawer, H et al. (2 more authors) (2021) Imaging Biological Pathways in Abdominal Aortic Aneurysms Using Positron Emission Tomography. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (5). pp. 1596-1606. ISSN 1079-5642
IG/15/1/31328
Chhabria, K., Vouros, A., Gray, C. et al. (7 more authors) (2019) Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish. Disease Models and Mechanisms, 12 (9). ISSN 1754-8403
II-LB-0216-20006
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
MC_PC_14109
Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322
MR/K001272/1
Parker, F, Batchelor, M orcid.org/0000-0001-6338-5698, Wolny, M et al. (3 more authors) (2018) A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo. Journal of Molecular Biology, 430 (10). pp. 1459-1478. ISSN 0022-2836
MR/K011154/1
Hartill, VL, Van de Hoek, G, Patel, MP et al. (25 more authors) (2018) DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human Molecular Genetics, 27 (3). pp. 529-545. ISSN 0964-6906
MR/K015613/1
Tiede, C orcid.org/0000-0003-0280-4005, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimer proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X
MR/K020919/1
Jones, R.J., De Bie, E.M.D.D., Groves, E. et al. (31 more authors) (2022) Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206 (1). pp. 81-93. ISSN 1073-449X
Rhodes, C.J., Otero-Núñez, P., Wharton, J. et al. (28 more authors) (2020) Whole blood RNA profiles associated with pulmonary arterial hypertension and clinical outcome. American Journal of Respiratory and Critical Care Medicine, 202 (4). pp. 586-594. ISSN 1073-449X
Swietlik, EM, Greene, D, Zhu, N et al. (56 more authors) (2021) Bayesian inference associates rare KDR variants with specific phenotypes in pulmonary arterial hypertension. Circulation: Genomic and Precision Medicine, 14 (1). pp. 57-70. ISSN 2574-8300
MR/L019051/1
Evans, EL, Cuthbertson, K, Endesh, N et al. (8 more authors) (2018) Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation. British Journal of Pharmacology, 175 (10). pp. 1744-1759. ISSN 0007-1188
Beech, DJ and Xiao, B (2018) Piezo channel mechanisms in health and disease. The Journal of Physiology, 596 (6). pp. 965-967. ISSN 0022-3751
MR/M008894/1
Goh, Z.M., Alabed, S. orcid.org/0000-0002-9960-7587, Shahin, Y. orcid.org/0000-0001-7425-7798 et al. (13 more authors) (2021) Right ventricular adaptation assessed using cardiac magnetic resonance predicts survival in pulmonary arterial hypertension. JACC: Cardiovascular Imaging, 14 (6). pp. 1271-1272. ISSN 1936-878X
MR/M014967/1
Holmes, M, Hurley, ME orcid.org/0000-0003-0553-3079, Sheard, TMD orcid.org/0000-0003-4940-3188 et al. (3 more authors) (2022) Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics. Philosophical Transactions of the Royal Society B: Biological Sciences, 377 (1864). 20210317. ISSN 0962-8436
Colman, MA orcid.org/0000-0003-2817-8508, Holmes, M, Whittaker, DG et al. (2 more authors) (2020) Multi-scale approaches for the simulation of cardiac electrophysiology: I - sub-cellular and stochastic calcium dynamics from cell to organ. Methods. ISSN 1046-2023
Perez Alday, EA, Whittaker, DG, Benson, AP orcid.org/0000-0003-4679-9842 et al. (1 more author) (2019) Effects of Heart Rate and Ventricular Wall Thickness on Non-invasive Mapping: An in silico Study. Frontiers in Physiology, 10 (308). ISSN 1664-042X
MR/N000285/
Miteva, KT, Pedicini, L, Wilson, LA et al. (9 more authors) (2019) Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies. Journal of Cell Biology, 218 (7). pp. 2232-2246. ISSN 0021-9525
MR/N011775/1
Duff, L orcid.org/0000-0002-4295-6356, Scarsbrook, AF orcid.org/0000-0002-4243-032X, Mackie, SL orcid.org/0000-0003-2483-5873 et al. (4 more authors) (2022) A methodological framework for AI-assisted diagnosis of active aortitis using radiomic analysis of FDG PET–CT images: Initial analysis. Journal of Nuclear Cardiology, 29 (6). pp. 3315-3331. ISSN 1071-3581
MR/P000096/1
Tulotta, C., Lefley, D.V., Moore, C.K. et al. (13 more authors) (2021) IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. npj Breast Cancer, 7 (1). 95.
MR/P002099/1
Morley, LC, Debant, M, Walker, JJ et al. (2 more authors) (2021) Placental blood flow sensing and regulation in fetal growth restriction. Placenta, 113. pp. 23-28. ISSN 0143-4004
Morley, LC orcid.org/0000-0002-1109-1396, Debant, M, Gaunt, HJ et al. (2 more authors) (2023) Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies. Reproduction & Fertility, 4 (1). e220100. ISSN 2633-8386
Morley, LC, Shi, J, Gaunt, HJ et al. (7 more authors) (2018) Piezo1 channels are mechanosensors in human fetoplacental endothelial cells. Molecular Human Reproduction, 24 (10). pp. 510-520. ISSN 1360-9947
MR/R01745X/1
Shi, J orcid.org/0000-0003-2179-8579, Hyman, AJ orcid.org/0000-0003-0874-6678, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247
MR/R023166/1
Byford, AR orcid.org/0000-0002-3936-2688, Forbes, K orcid.org/0000-0002-3745-1337 and Scott, EM orcid.org/0000-0001-5395-8261 (2022) Glucose Treatment Targets in Pregnancy - A Review of Evidence and Guidelines. Current Diabetes Reviews, 19 (2). e220422203917. ISSN 1573-3998
Byford, A., Walsh, K., Wang, D. et al. (3 more authors) (2024) Temporal Periods of Mild Hyperglycaemia in Pregnancies Complicated by GDM and LGA Impacts Pathways Associated with Hofbauer Cell Polarization and Placental Vascularisation. In: Reproductive Sciences. SRI 2024 Annual Scientifc Meeting, 12-16 Mar 2024, Vancouver, Canada. Springer , 249A-249A.
Byford, A, Walsh, K, Scott, E et al. (1 more author) (2022) Temporal periods of maternal hyperglycaemia in gestational diabetes alter placental transcriptome networks associated with inflammation and vascular development. In: SLIMP 2022, 04-06 May 2022, Online.
Owen, M.D., Quilang, R., Byford, A. et al. (13 more authors) (2024) Maternal Extracellular Vesicle Derived miR-375-3p Promotes Fetal Overgrowth in Healthy Pregnant Mice. In: Reproductive Sciences. SRI 2024 Annual Scientific Meeting, 12-16 Mar 2024, Vancouver, Canada. Springer , 57A-57A.
Owen, M.D., Kennedy, M.G., Quilang, R.C. et al. (2 more authors) (2024) The Role of microRNAs in Pregnancies Complicated by Maternal Diabetes. Clinical Science, 138 (18). pp. 1179-1207. ISSN 0143-5221
Byford, A orcid.org/0000-0002-3936-2688, Baird-Rayner, C and Forbes, K orcid.org/0000-0002-3745-1337 (2021) Don’t sugar coat it: the effects of gestational diabetes on the placental vasculature. The Biochemist, 43 (2). pp. 34-39. ISSN 0954-982X
Owen, MD, Baker, BC, Scott, EM et al. (1 more author) (2021) Interaction Between Metformin, Folate and Vitamin B12 and the Potential Impact on Fetal Growth and Long-Term Metabolic Health in Diabetic Pregnancies. International Journal of Molecular Sciences, 22 (11). 5759. ISSN 1661-6596
MR/S021108/1
Howard, J.P., Wood, F.A., Finegold, J.A. et al. (12 more authors) (2021) Side effect patterns in a crossover trial of statin, placebo, and no treatment. Journal of the American College of Cardiology, 78 (12). pp. 1210-1222. ISSN 0735-1097
MR/S025472/1
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
MR/W00366X/1
X, S. orcid.org/0000-0002-3836-9984, Aitken, C., Mehta, V. orcid.org/0000-0002-5289-5526 et al. (8 more authors) (2024) Controversy in mechanotransduction: the role of endothelial cell-cell junctions in fluid shear stress sensing. Journal of Cell Science, 137 (17). jcs262348. ISSN 0021-9533
MR/W02067X/1
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
Hornsby, H. orcid.org/0000-0002-6657-9743, Nicols, A.R. orcid.org/0000-0002-1813-3819, Longet, S. orcid.org/0000-0001-5026-431X et al. (40 more authors) (2023) Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history. Nature Communications, 14 (1). 5065. ISSN 2041-1723
Neale, I. orcid.org/0000-0001-7026-7390, Ali, M. orcid.org/0000-0003-0170-7182, Kronsteiner, B. orcid.org/0000-0003-0867-2867 et al. (26 more authors) (2023) CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study. mBio, 14 (5). e0121223. ISSN 2161-2129
MR/m000532/1
Richardson, L, Wang, D, Hughes, R et al. (2 more authors) (2022) RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Scientific Reports, 12 (1). 2841. ISSN 2045-2322
Hartill, VL, Van de Hoek, G, Patel, MP et al. (25 more authors) (2018) DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human Molecular Genetics, 27 (3). pp. 529-545. ISSN 0964-6906
N/A
Nazemi, M. and Rainero, E. orcid.org/0000-0003-1402-8701 (2020) Cross-talk between the tumor microenvironment, extracellular matrix, and cell metabolism in cancer. Frontiers in Oncology, 10. 239.
Nazemi, M. and Rainero, E. orcid.org/0000-0003-1402-8701 (2020) Cross-talk between the tumor microenvironment, extracellular matrix, and cell metabolism in cancer. Frontiers in Oncology, 10. 239.
NC/P001173/1
Chhabria, K., Vouros, A., Gray, C. et al. (7 more authors) (2019) Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish. Disease Models and Mechanisms, 12 (9). ISSN 1754-8403
NH/12/1/29382
Hauser, JR, Beard, HA, Bayana, ME et al. (3 more authors) (2016) Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole. Beilstein Journal of Organic Chemistry, 12. pp. 2019-2025. ISSN 1860-5397
Tiede, C orcid.org/0000-0003-0280-4005, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimer proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X
NIHR-CS--012-032
Kearney, J, Drozd, M orcid.org/0000-0003-0255-4624, Walker, AMN et al. (9 more authors) (2021) Diabetes, gender and deterioration in estimated glomerular filtration rate in patients with chronic heart failure: ten-year prospective cohort study. Diabetes and Vascular Disease Research, 18 (1). pp. 1-7. ISSN 1479-1641
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
NIHR/CS/009/004
Munyombwe, T., Dondo, T.B., Hall, M. orcid.org/0000-0003-1246-2627 et al. (10 more authors) (2024) Corrigendum to: Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort. European Heart Journal - Quality of Care and Clinical Outcomes, 10 (2). p. 189. ISSN 2058-5225
NIHRDH-II-LB-0216-20006
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
NOT GIVEN
Elpidorou, M, Best, S, Poulter, JA orcid.org/0000-0003-2048-5693 et al. (4 more authors) (2020) Novel loss-of-function mutation in HERC2 is associated with severe developmental delay and paediatric lethality. Journal of Medical Genetics. ISSN 0022-2593
Cuvertino, S, Hartill, V, Colyer, A et al. (32 more authors) (2020) A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine, 22 (5). pp. 867-877. ISSN 1098-3600
Bridge, KI, Bollen, L, Zhong, J et al. (7 more authors) (2017) Thrombin-Activatable Fibrinolysis Inhibitor in Human Abdominal Aortic Aneurysm Disease. Journal of Thrombosis and Haemostasis, 15 (11). pp. 2218-2225. ISSN 1538-7933
Hartill, VL, Van de Hoek, G, Patel, MP et al. (25 more authors) (2018) DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport. Human Molecular Genetics, 27 (3). pp. 529-545. ISSN 0964-6906
NOT STATES
Sengupta, A, Patel, PA, Yuldasheva, NY orcid.org/0000-0001-6213-6358 et al. (13 more authors) (2018) Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice. Endocrinology, 159 (8). pp. 2917-2925. ISSN 0013-7227
Not Known
Gandhi, R, Bell, M orcid.org/0000-0002-5138-0985, Bailey, M orcid.org/0000-0001-5038-1970 et al. (1 more author) (2021) Prospect of positron emission tomography for abdominal aortic aneurysm risk stratification. Journal of Nuclear Cardiology, 28 (5). pp. 2272-2282. ISSN 1071-3581
Gandhi, R, Bailey, MA orcid.org/0000-0001-5038-1970 and Tsoumpas, C orcid.org/0000-0002-4971-2477 (2021) Radionuclide molecular imaging of abdominal aortic aneurysms for risk stratification and non-invasive therapy assessment. Clinical and Translational Medicine, 11 (4). e386. ISSN 2001-1326
Beech, DJ and Kalli, AC orcid.org/0000-0001-7156-9403 (2019) Force Sensing by Piezo Channels in Cardiovascular Health and Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 39 (11). pp. 2228-2239. ISSN 1079-5642
Berger, M, Wraith, K, Woodward, C et al. (6 more authors) (2019) Dyslipidemia-associated atherogenic oxidized lipids induce platelet hyperactivity through phospholipase Cγ2-dependent reactive oxygen species generation. Platelets, 30 (4). pp. 467-472. ISSN 0953-7104
Gandhi, R orcid.org/0000-0002-9581-9312, Cawthorne, C, Craggs, LJL orcid.org/0000-0001-9192-1072 et al. (9 more authors) (2021) Cell proliferation detected using [18F]FLT PET/CT as an early marker of abdominal aortic aneurysm. Journal of Nuclear Cardiology, 28 (5). pp. 1961-1971. ISSN 1071-3581
Duff, L orcid.org/0000-0002-4295-6356, Scarsbrook, AF orcid.org/0000-0002-4243-032X, Mackie, SL orcid.org/0000-0003-2483-5873 et al. (4 more authors) (2022) A methodological framework for AI-assisted diagnosis of active aortitis using radiomic analysis of FDG PET–CT images: Initial analysis. Journal of Nuclear Cardiology, 29 (6). pp. 3315-3331. ISSN 1071-3581
Deivasikamani, V, Dhayalan, S, Abudushalamu, Y et al. (12 more authors) (2019) Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific Reports, 9. 16876. ISSN 2045-2322
Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322
Bell, M orcid.org/0000-0002-5138-0985, Gandhi, R, Shawer, H et al. (2 more authors) (2021) Imaging Biological Pathways in Abdominal Aortic Aneurysms Using Positron Emission Tomography. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (5). pp. 1596-1606. ISSN 1079-5642
Berger, M, Raslan, Z, Aburima, A et al. (7 more authors) (2020) Atherogenic Lipid Stress Induces Platelet Hyperactivity Through CD36-Mediated Hyposensitivity To Prostacyclin-; The Role Of Phosphodiesterase 3A. Haematologica, 105 (3). pp. 808-819. ISSN 0390-6078
Cuvertino, S, Hartill, V, Colyer, A et al. (32 more authors) (2020) A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome. Genetics in Medicine, 22 (5). pp. 867-877. ISSN 1098-3600
Owen, M.D., Kennedy, M.G., Quilang, R.C. et al. (2 more authors) (2024) The Role of microRNAs in Pregnancies Complicated by Maternal Diabetes. Clinical Science, 138 (18). pp. 1179-1207. ISSN 0143-5221
Cheng, CW orcid.org/0000-0002-2873-0828, Deivasikamani, V, Ludlow, MJ et al. (4 more authors) (2020) Genetic variants of PIEZO1 associate with COVID-19 fatality. [Preprint]
Gallagher, H, Hendrickse, PW, Pereira, MG et al. (1 more author) (2023) Skeletal muscle atrophy, regeneration, and dysfunction in heart failure: Impact of exercise training. Journal of Sport and Health Science, 12 (5). pp. 557-567. ISSN 2095-2546
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
PG/06/012/20287
Turner, NA orcid.org/0000-0002-4957-5433 and Blythe, NM (2019) Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling. Journal of cardiovascular development and disease, 6 (3). 27.
PG/07/057/23215
Gale, CP orcid.org/0000-0003-4732-382X, Cattle, BA, Baxter, PD orcid.org/0000-0003-2699-3103 et al. (6 more authors) (2013) Age-dependent inequalities in improvements in mortality occur early after acute myocardial infarction in 478,242 patients in the Myocardial Ischaemia National Audit Project (MINAP) registry. International Journal of Cardiology, 168 (2). pp. 881-887. ISSN 0167-5273
PG/07/061/23277
Parker, F, Batchelor, M orcid.org/0000-0001-6338-5698, Wolny, M et al. (3 more authors) (2018) A1603P and K1617del, Mutations in β-Cardiac Myosin Heavy Chain that Cause Laing Early-Onset Distal Myopathy, Affect Secondary Structure and Filament Formation In Vitro and In Vivo. Journal of Molecular Biology, 430 (10). pp. 1459-1478. ISSN 0022-2836
PG/08/020/24617
Kearney, J, Drozd, M orcid.org/0000-0003-0255-4624, Walker, AMN et al. (9 more authors) (2021) Diabetes, gender and deterioration in estimated glomerular filtration rate in patients with chronic heart failure: ten-year prospective cohort study. Diabetes and Vascular Disease Research, 18 (1). pp. 1-7. ISSN 1479-1641
PG/08/052/25172
Hethershaw, EL orcid.org/0000-0002-4366-278X, Adamson, PJ, Smith, KA orcid.org/0000-0001-5695-7117 et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933
PG/08/060/25340
Harris, E, Rakobowchuk, M and Birch, KM orcid.org/0000-0001-7796-8640 (2017) Interval exercise increases angiogenic cell function in postmenopausal women. BMJ Open Sport and Exercise Medicine, 3 (1). e000248. ISSN 2055-7647
PG/08/120/26338
Lall, VK, Bruce, G, Voytenko, L et al. (5 more authors) (2017) Physiologic regulation of heart rate and blood pressure involves connexin 36-containing gap junctions. FASEB Journal, 31 (9). pp. 3966-3977. ISSN 0892-6638
PG/09/013/26885
Al-Owais, MM, Hettiarachchi, NT, Boyle, JP orcid.org/0000-0001-5786-6559 et al. (6 more authors) (2017) Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5. Cell Death and Disease, 8. e3163. ISSN 2041-4889
Al-Owais, MM, Hettiarachchi, NT, Kirton, HM et al. (5 more authors) (2017) A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide–induced proarrhythmic early afterdepolarizations. FASEB Journal, 31 (11). pp. 4845-4854. ISSN 0892-6638
PG/09/051/27828
MacDougall, DA, Pugh, SD, Bassi, HS et al. (3 more authors) (2017) Simvastatin promotes cardiac myocyte relaxation in association with phosphorylation of Troponin I. Frontiers in Pharmacology, 8. 203. ISSN 1663-9812
PG/10/68/28528
Abuarab, N, Munsey, TS, Jiang, L-H orcid.org/0000-0001-6398-0411 et al. (2 more authors) (2017) High glucose–induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn2+-mediated mitochondrial fission. Science Signaling, 10 (490). eaal4161. ISSN 1945-0877
PG/10/93/28650
Norman, R, Fuller, W and Calaghan, S orcid.org/0000-0002-9145-2576 (2018) Caveolae and the cardiac myocyte. Current Opinion in Physiology, 1. pp. 59-67. ISSN 2468-8673
PG/11/110/29248
Mylonas, KJ, Turner, NA, Bageghni, SA et al. (10 more authors) (2017) 11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI. Journal of Endocrinology, 233 (3). pp. 315-327. ISSN 0022-0795
Bageghni, SA orcid.org/0000-0001-9640-3717, Hemmings, KE, Zava, N et al. (5 more authors) (2018) Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism. The FASEB Journal, 32 (9). pp. 4941-4954. ISSN 0892-6638
Turner, NA orcid.org/0000-0002-4957-5433 and Blythe, NM (2019) Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling. Journal of cardiovascular development and disease, 6 (3). 27.
PG/11/116/29288
Williams, D.M. orcid.org/0000-0001-8483-021X, Hornsby, H.R. orcid.org/0000-0002-6657-9743, Shehata, O.M. et al. (19 more authors) (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26 (7). 107056. ISSN 2589-0042
Hornsby, H. orcid.org/0000-0002-6657-9743, Nicols, A.R. orcid.org/0000-0002-1813-3819, Longet, S. orcid.org/0000-0001-5026-431X et al. (40 more authors) (2023) Omicron infection following vaccination enhances a broad spectrum of immune responses dependent on infection history. Nature Communications, 14 (1). 5065. ISSN 2041-1723
Neale, I. orcid.org/0000-0001-7026-7390, Ali, M. orcid.org/0000-0003-0170-7182, Kronsteiner, B. orcid.org/0000-0003-0867-2867 et al. (26 more authors) (2023) CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study. mBio, 14 (5). e0121223. ISSN 2161-2129
Errington, N. orcid.org/0000-0001-6768-7394, Iremonger, J., Pickworth, J.A. orcid.org/0000-0002-7199-364X et al. (13 more authors) (2021) A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine, 69. 103444. ISSN 2352-3964
Dijokaite-Guraliuc, A., Das, R., Zhou, D. et al. (44 more authors) (2023) Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Reports, 42 (4). 112271. ISSN 2211-1247
Khassafi, F., Chelladurai, P. orcid.org/0000-0002-8258-5115, Valasarajan, C. et al. (23 more authors) (2023) Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. Nature Cardiovascular Research, 2. pp. 917-936. ISSN 2731-0590
PG/11/126/29321
Al Musa, T, Uddin, A, Loveday, C et al. (14 more authors) (2019) Silent cerebral infarction and cognitive function following TAVI: an observational two-centre UK comparison of the first-generation CoreValve and second-generation Lotus valve. BMJ Open, 9 (1). e022329. ISSN 2044-6055
Al Musa, T, Uddin, A, Dobson, LE et al. (7 more authors) (2018) Cardiovascular magnetic resonance assessment of 1st generation CoreValve and 2nd generation Lotus valves. Journal of Interventional Cardiology, 31 (3). pp. 391-399. ISSN 0896-4327
PG/11/15/28775
Jones, S, Walton, R, Morton, M et al. (1 more author) (2019) K2p3.1 Protein is Expressed as a Transmural Gradient across the Rat Left Ventricular Free Wall. Journal of Cardiovascular Electrophysiology, 30 (3). pp. 383-391. ISSN 1045-3873
Jones, SA and Lancaster, MK (2015) Progressive age-associated activation of JNK associates with conduction disruption in the aged atrium. Mechanisms of Ageing and Development, 146-14. pp. 72-80. ISSN 0047-6374
Walton, RD, Jones, SA, Rostron, KA et al. (4 more authors) (2016) Interactions of short-term and chronic treadmill training with aging of the left ventricle of the heart. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences, 71 (8). pp. 1005-1013. ISSN 1079-5006
PG/11/80/29135
Bageghni, SA orcid.org/0000-0001-9640-3717, Hemmings, KE, Zava, N et al. (5 more authors) (2018) Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism. The FASEB Journal, 32 (9). pp. 4941-4954. ISSN 0892-6638
Hemmings, KE orcid.org/0000-0002-4967-6314, Bageghni, SA orcid.org/0000-0001-9640-3717, Maqbool, A et al. (5 more authors) (2019) Fibroblast-Specific Deletion of Interleukin-1 Receptor 1 (IL-₁R₁) Is Cardioprotective in an Experimental Model of Myocardial Infarction. In: Cardiovascular Drugs and Therapy. BSCR Autumn Meeting 2018 and Early Career Symposium, 10-11 Sep 2018, University of Sheffield. Springer , p. 273.
Bageghni, SA orcid.org/0000-0001-9640-3717, Hemmings, KE, Yuldasheva, NY et al. (11 more authors) (2019) Fibroblast-specific deletion of IL-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. JCI insight, 4 (17). e125074. ISSN 2379-3708
Turner, NA orcid.org/0000-0002-4957-5433 and Blythe, NM (2019) Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling. Journal of cardiovascular development and disease, 6 (3). 27.
PG/11/80/29135; PG/16/31/32130; PG/13/55/30365
Bageghni, S.A., Hemmings, K.E., Yuldasheva, N.Y. et al. (11 more authors) (2019) Fibroblast-specific deletion of IL-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. JCI Insight, 4 (17). ISSN 2379-3708
PG/11/89/29085
Witte, KK orcid.org/0000-0002-7146-7105, Patel, PA, Walker, AMN et al. (8 more authors) (2018) Socioeconomic deprivation and mode-specific outcomes in patients with chronic heart failure. Heart, 104 (12). pp. 993-998. ISSN 1355-6037
PG/12/56/29748
Haywood, NJ orcid.org/0000-0002-8762-7257, Cordell, PA, Tang, KY et al. (8 more authors) (2017) Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain. Diabetes, 66 (2). pp. 287-299. ISSN 0012-1797
PG/12/88/29951
Lotteau, S, Ivarsson, N, Yang, Z et al. (10 more authors) (2019) A Mechanism for Statin-Induced Susceptibility to Myopathy. JACC: Basic to Translational Science, 4 (4). pp. 509-523. ISSN 2452-302X
Venturi, E, Lindsay, C, Lotteau, S et al. (9 more authors) (2018) Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform. British Journal of Pharmacology, 175 (6). pp. 938-952. ISSN 0007-1188
PG/13/3/29924
Temple, IP, Logantha, SJRJ, Absi, M et al. (20 more authors) (2016) Atrioventricular Node Dysfunction and Ion Channel Transcriptome in Pulmonary Hypertension. Circulation: Arrhythmia and Electrophysiology, 9 (12). e003432. ISSN 1941-3149
Fowler, ED, Drinkhill, MJ, Norman, R et al. (7 more authors) (2018) Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca²⁺ handling dysfunction in rats with pulmonary artery hypertension. Journal of Molecular and Cellular Cardiology, 120. pp. 74-83. ISSN 0022-2828
Fowler, ED, Drinkhill, MJ orcid.org/0000-0002-9007-1130, Stones, R et al. (1 more author) (2018) Diastolic dysfunction in pulmonary artery hypertension: Creatine kinase and the potential therapeutic benefit of beta‐blockers. Clinical and Experimental Pharmacology and Physiology, 45 (4). pp. 384-389. ISSN 0305-1870
Fowler, ED, Hauton, D, Boyle, J et al. (3 more authors) (2019) Energy Metabolism in the Failing Right Ventricle: Limitations of Oxygen Delivery and the Creatine Kinase System. International Journal of Molecular Sciences, 20 (8). 1805. ISSN 1661-6596
Hardy, MEL, Pervolaraki, E, Bernus, O et al. (1 more author) (2018) Dynamic Action Potential Restitution Contributes to Mechanical Restitution in Right Ventricular Myocytes From Pulmonary Hypertensive Rats. Frontiers in Physiology, 9. 205. ISSN 1664-042X
PG/13/55/30365
Helyes, Z., Tékus, V., Szentes, N. et al. (13 more authors) (2019) Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1–induced mechanisms. Proceedings of the National Academy of Sciences, 116 (26). pp. 13067-13076. ISSN 0027-8424
PG/13/61/30410
Al-Owais, MM, Hettiarachchi, NT, Boyle, JP orcid.org/0000-0001-5786-6559 et al. (6 more authors) (2017) Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5. Cell Death and Disease, 8. e3163. ISSN 2041-4889
Al-Owais, MM, Hettiarachchi, NT, Kirton, HM et al. (5 more authors) (2017) A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide–induced proarrhythmic early afterdepolarizations. FASEB Journal, 31 (11). pp. 4845-4854. ISSN 0892-6638
PG/13/81/30474
Schiele, F, Gale, CP orcid.org/0000-0003-4732-382X, Simon, T et al. (8 more authors) (2017) Assessment of Quality Indicators for Acute Myocardial Infarction in the FAST-MI (French Registry of Acute ST-Elevation or Non–ST-Elevation Myocardial Infarction) Registries. Circulation: Cardiovascular Quality and Outcomes, 10 (6). e003336. ISSN 1941-7705
Dondo, TB, Hall, M orcid.org/0000-0003-1246-2627, West, RM orcid.org/0000-0001-7305-3654 et al. (9 more authors) (2017) β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction. Journal of the American College of Cardiology, 69 (22). pp. 2710-2720. ISSN 0735-1097
Dondo, TB, Hall, M orcid.org/0000-0003-1246-2627, Timmis, AD et al. (9 more authors) (2016) Geographic variation in the treatment of non-ST-segment myocardial infarction in the English National Health Service: a cohort study. BMJ Open, 6 (7). e011600. ISSN 2044-6055
Hall, M orcid.org/0000-0003-1246-2627, Bebb, OJ orcid.org/0000-0003-0974-9109, Dondo, TB et al. (11 more authors) (2018) Guideline-indicated treatments and diagnostics, GRACE risk score, and survival for non-ST elevation myocardial infarction. European Heart Journal, 39 (42). pp. 3798-3806. ISSN 0195-668X
Hall, M orcid.org/0000-0003-1246-2627, Dondo, TB, Yan, AT et al. (7 more authors) (2018) Multimorbidity and survival for patients with acute myocardial infarction in England and Wales: Latent class analysis of a nationwide population-based cohort. PLoS Medicine, 15 (3). e1002501. ISSN 1549-1676
Bebb, O, Hall, M, Fox, KAA et al. (5 more authors) (2017) Performance of hospitals according to the ESC ACCA quality indicators and 30-day mortality for acute myocardial infarction: national cohort study using the United Kingdom Myocardial Ischaemia National Audit Project (MINAP) register. European Heart Journal, 38 (13). pp. 974-982. ISSN 0195-668X
Alabas, OA, Gale, CP orcid.org/0000-0003-4732-382X, Hall, M orcid.org/0000-0003-1246-2627 et al. (6 more authors) (2017) Sex Differences in Treatments, Relative Survival, and Excess Mortality Following Acute Myocardial Infarction: National Cohort Study Using the SWEDEHEART Registry. Journal of the American Heart Association, 6 (12). e007123. ISSN 2047-9980
Wilkinson, C orcid.org/0000-0003-0748-0150, Bebb, O, Dondo, TB et al. (7 more authors) (2019) Sex differences in quality indicator attainment for myocardial infarction: A nationwide cohort study. Heart, 105 (7). pp. 516-523. ISSN 1355-6037
Dondo, TB, Hall, M orcid.org/0000-0003-1246-2627, Munyombwe, T orcid.org/0000-0002-1307-6691 et al. (7 more authors) (2020) A nationwide causal mediation analysis of survival following ST-elevation myocardial infarction. Heart, 106 (10). pp. 765-771. ISSN 1355-6037
Munyombwe, T., Dondo, T.B., Hall, M. orcid.org/0000-0003-1246-2627 et al. (10 more authors) (2024) Corrigendum to: Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort. European Heart Journal - Quality of Care and Clinical Outcomes, 10 (2). p. 189. ISSN 2058-5225
Wu, J orcid.org/0000-0001-6093-599X, Gale, CP orcid.org/0000-0003-4732-382X, Hall, M orcid.org/0000-0003-1246-2627 et al. (7 more authors) (2018) Impact of initial hospital diagnosis on mortality for acute myocardial infarction: A national cohort study. European Heart Journal: Acute Cardiovascular Care, 7 (2). pp. 139-148. ISSN 2048-8726
PG/14/10/30641
McDiarmid, AK, Swoboda, PP orcid.org/0000-0001-7162-7079, Erhayiem, B et al. (10 more authors) (2016) Athletic Cardiac Adaptation in Males Is a Consequence of Elevated Myocyte Mass. Circulation: Cardiovascular Imaging, 9 (4). e003579. ISSN 1941-9651
PG/14/15/30691
Olfert, IM, Baum, O, Hellsten, Y et al. (1 more author) (2016) Advances and challenges in skeletal muscle angiogenesis. American Journal of Physiology - Heart and Circulatory Physiology, 310 (3). H326-H336. ISSN 0363-6135
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
PG/14/38/30862
Gomez, I., Ward, B., Souilhol, C. et al. (21 more authors) (2020) Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium. Nature Communications, 11 (1). 214.
Ward, B., Gomez, I., Willis, J. et al. (5 more authors) (2017) Neutrophil microvesicles are increased by high-fat overfeeding and enhance monocyte recruitment to endothelial cells under disturbed flow. In: Atherosclerosis. 85th EAS Congress, 23-26 Apr 2017, Prague, Czech Republic. Elsevier , e123-e124.
PG/14/54/30939
Maqbool, A, Watt, N, Haywood, N et al. (17 more authors) (2020) Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance related vascular damage. American Journal of Physiology: Cell Physiology. ISSN 0363-6143
PG/15/2/31208
Haywood, NJ, Wolny, M, Rogers, B et al. (4 more authors) (2016) Hypertrophic cardiomyopathy mutations in the calponin-homology domain of ACTN2 affect actin binding and cardiomyocyte Z-disc incorporation. Biochemical Journal, 473 (16). pp. 2485-2493. ISSN 0264-6021
PG/15/42/31563
Norman, R, Fuller, W and Calaghan, S orcid.org/0000-0002-9145-2576 (2018) Caveolae and the cardiac myocyte. Current Opinion in Physiology, 1. pp. 59-67. ISSN 2468-8673
PG/15/7/31235
Howard, J.P., Wood, F.A., Finegold, J.A. et al. (12 more authors) (2021) Side effect patterns in a crossover trial of statin, placebo, and no treatment. Journal of the American College of Cardiology, 78 (12). pp. 1210-1222. ISSN 0735-1097
PG/15/73/31743
Drozd, M., Bruns, A-F., Yuldasheva, N. et al. (20 more authors) (2025) Endothelial Insulin-like Growth Factor-1 Signaling Regulates Vascular Barrier Function and Atherogenesis. Cardiovascular Research. ISSN 0008-6363 (In Press)
Drozd, M orcid.org/0000-0003-0255-4624, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Maqbool, A et al. (9 more authors) (2018) Increasing endothelial insulin-like growth factor-1 receptor expression reduces circulating leukocytes and protects against atherosclerosis. In: Cardiovascular Research. Annual meeting of the British Atherosclerosis Society, 06-07 Sep 2018, Cambridge. Oxford University Press , S3-S3.
PG/16/31/32130
Hemmings, KE orcid.org/0000-0002-4967-6314, Bageghni, SA orcid.org/0000-0001-9640-3717, Maqbool, A et al. (5 more authors) (2019) Fibroblast-Specific Deletion of Interleukin-1 Receptor 1 (IL-₁R₁) Is Cardioprotective in an Experimental Model of Myocardial Infarction. In: Cardiovascular Drugs and Therapy. BSCR Autumn Meeting 2018 and Early Career Symposium, 10-11 Sep 2018, University of Sheffield. Springer , p. 273.
Bageghni, SA orcid.org/0000-0001-9640-3717, Hemmings, KE, Yuldasheva, NY et al. (11 more authors) (2019) Fibroblast-specific deletion of IL-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction. JCI insight, 4 (17). e125074. ISSN 2379-3708
Turner, NA orcid.org/0000-0002-4957-5433 and Blythe, NM (2019) Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling. Journal of cardiovascular development and disease, 6 (3). 27.
PG/16/6/31941
Onselaer, M-B, Hardy, AT, Wilson, C et al. (11 more authors) (2017) Fibrin and D-dimer bind to monomeric GPVI. Blood Advances, 1 (19). pp. 1495-1504. ISSN 2473-9529
Heal, SL, Hardy, LJ, Wilson, CL et al. (4 more authors) (2022) Novel interaction of properdin and coagulation factor XI: Crosstalk between complement and coagulation. Research and Practice in Thrombosis and Haemostasis, 6 (4). e12715. ISSN 2475-0379
PG/16/60/32292
Macrae, F, Bowman, P, Linton, E et al. (9 more authors) (2018) BSH18-PO-150: Complement inhibition with Eculizumab affects fibrinogen levels and clot Structure in patients with Paroxysmal Nocturnal Haemoglobinuria. In: British Journal of Haematology. 58th Annual Scientific Meeting of the British Society for Haematology, 16-18 Apr 2018, Liverpool, UK. Wiley , p. 130.
Feller, T. orcid.org/0000-0002-9137-5881, McPherson, H.R., Connell, S.D. orcid.org/0000-0003-2500-5724 et al. (1 more author) (2024) Fibrinogen αC-region acts as a functional safety latch: Implications for a fibrin biomechanical behaviour model. Acta Biomaterialia, 189. pp. 179-191. ISSN 1742-7061
Macrae, FL orcid.org/0000-0002-7092-0422, Duval, C orcid.org/0000-0002-4870-6542, Papareddy, P et al. (13 more authors) (2018) A fibrin biofilm covers blood clots and protects from microbial invasion. Journal of Clinical Investigation, 128 (8). pp. 3356-3368. ISSN 0021-9738
PG/16/74/32374
Pervolaraki, E, White, E and Benson, A orcid.org/0000-0003-4679-9842 (2019) Investigating the Beneficial Effects of Voluntary Exercise in Rats with Pulmonary Artery Hypertension. In: Biophysical Journal. BPS19: 63rd Annual Meeting of the Biophysical Society, 02-06 Mar 2019, Baltimore, MD, USA. Elsevier , 423a-423a.
Whittaker, DG orcid.org/0000-0002-2757-5491, Benson, AP orcid.org/0000-0003-4679-9842, Teh, I et al. (2 more authors) (2019) Investigation of the Role of Myocyte Orientations in Cardiac Arrhythmia Using Image-Based Models. Biophysical Journal, 117 (12). pp. 2396-2408. ISSN 0006-3495
Howlett, L.A. orcid.org/0000-0002-7786-5569, Stevenson‐Cocks, H., Colman, M.A. et al. (2 more authors) (2023) Ionic current changes underlying action potential repolarization responses to physiological pacing and adrenergic stimulation in adult rat ventricular myocytes. Physiological Reports, 11 (14). e15766. ISSN 2051-817X
Holmes, M, Hurley, ME orcid.org/0000-0003-0553-3079, Sheard, TMD orcid.org/0000-0003-4940-3188 et al. (3 more authors) (2022) Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics. Philosophical Transactions of the Royal Society B: Biological Sciences, 377 (1864). 20210317. ISSN 0962-8436
Colman, MA orcid.org/0000-0003-2817-8508, Holmes, M, Whittaker, DG et al. (2 more authors) (2020) Multi-scale approaches for the simulation of cardiac electrophysiology: I - sub-cellular and stochastic calcium dynamics from cell to organ. Methods. ISSN 1046-2023
Perez Alday, EA, Whittaker, DG, Benson, AP orcid.org/0000-0003-4679-9842 et al. (1 more author) (2019) Effects of Heart Rate and Ventricular Wall Thickness on Non-invasive Mapping: An in silico Study. Frontiers in Physiology, 10 (308). ISSN 1664-042X
PG/17/16/32853
Imrie, H, Viswambharan, H orcid.org/0000-0002-7616-5026, Haywood, NJ et al. (14 more authors) (2022) Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity. Adipocyte, 11 (1). pp. 366-378. ISSN 2162-3945
Deivasikamani, V, Dhayalan, S, Abudushalamu, Y et al. (12 more authors) (2019) Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific Reports, 9. 16876. ISSN 2045-2322
PG/17/28/32943
Farzi, M orcid.org/0000-0003-4663-2110, McClymont, D, Whittington, H et al. (7 more authors) (2021) Assessing Myocardial Microstructure with Biophysical Models of Diffusion MRI. IEEE transactions on medical imaging, 40 (12). pp. 3775-3786. ISSN 0278-0062
Teh, I, Romero, W, Boyle, J orcid.org/0000-0002-4219-9383 et al. (23 more authors) (2022) Validation of cardiac diffusion tensor imaging sequences: A multi-centre test-retest phantom study. NMR in Biomedicine, 35 (6). e4685. ISSN 0952-3480
PG/17/72/33255
Tiede, C orcid.org/0000-0003-0280-4005, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimer proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X
PG/18/39/33618
Walmsley, R., Steele, D.S., Papaspyros, S. et al. (1 more author) (2024) Sunitinib malate induces cell death in adult human cardiac progenitor cells. Current Research in Toxicology, 6. 100167. ISSN 2666-027X
PG/18/63/33968
Tardajos Ayllon, B., Bowden, N., Souilhol, C. et al. (10 more authors) (2025) Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways. Cardiovascular Research. cvaf024. ISSN 0008-6363
PG/18/72/34033
Chin, C, Ravichandran, R, Sanborn, K et al. (10 more authors) (2023) Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis. Cell Reports Medicine, 4 (3). 100945. ISSN 2666-3791
PG/19/1/34076
Szczepankiewicz, F, Sjölund, J, Dall’Armellina, E et al. (4 more authors) (2021) Motion-compensated gradient waveforms for tensor-valued diffusion encoding by constrained numerical optimization. Magnetic Resonance in Medicine, 85 (4). pp. 2117-2126. ISSN 0740-3194
Farzi, M orcid.org/0000-0003-4663-2110, McClymont, D, Whittington, H et al. (7 more authors) (2021) Assessing Myocardial Microstructure with Biophysical Models of Diffusion MRI. IEEE transactions on medical imaging, 40 (12). pp. 3775-3786. ISSN 0278-0062
Teh, I, Romero, W, Boyle, J orcid.org/0000-0002-4219-9383 et al. (23 more authors) (2022) Validation of cardiac diffusion tensor imaging sequences: A multi-centre test-retest phantom study. NMR in Biomedicine, 35 (6). e4685. ISSN 0952-3480
Moulin, K., Stoeck, C.T. orcid.org/0000-0001-8670-0929, Axel, L. et al. (15 more authors) (2023) In Vivo Cardiac Diffusion Imaging Without Motion-Compensation Leads to Unreasonably High Diffusivity. Journal of Magnetic Resonance Imaging, 58 (6). pp. 1990-1991. ISSN 1053-1807
Teh, I orcid.org/0000-0002-6705-3129, Shelley, D, Boyle, JH et al. (10 more authors) (2023) Cardiac q-space trajectory imaging by motion-compensated tensor-valued diffusion encoding in human heart in vivo. Magnetic Resonance in Medicine, 90 (1). pp. 150-165. ISSN 0740-3194
PG/19/2/34084
Bauer, CC, Minard, A, Pickles, IB et al. (9 more authors) (2020) Xanthine-based photoaffinity probes allow assessment of ligand engagement by TRPC5 channels. RSC Chemical Biology. ISSN 2633-0679
Keeble, AH, Yadav, VK, Ferla, MP et al. (5 more authors) (2022) DogCatcher allows loop-friendly protein-protein ligation. Cell chemical biology, 29 (2). pp. 339-350. ISSN 2451-9448
Dryn, D.O., Melnyk, M.I., Bon, R.S. orcid.org/0000-0003-1733-3680 et al. (2 more authors) (2023) Pico145 inhibits TRPC4-mediated mICAT and postprandial small intestinal motility. Biomedicine & Pharmacotherapy, 168. 115672. ISSN 0753-3322
Mak, Y-Y, Loong, B-J, Millns, P et al. (8 more authors) (2022) Schwarzinicine A inhibits transient receptor potential canonical channels and exhibits overt vasorelaxation effects. Phytotherapy Research, 36 (7). pp. 2952-2963. ISSN 0951-418X
Govindaraju, K., Mak, Y.Y., Lee, F.K. et al. (6 more authors) (2023) Vasorelaxant effect of a phenylethylamine analogue based on schwarzinicine A an alkaloid isolated from the leaves of Ficus schwarzii. Phytochemistry Letters, 59. pp. 24-35. ISSN 1874-3900
Baradaran-Heravi, A, Bauer, CC, Pickles, IB et al. (7 more authors) (2022) Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. Journal of Biological Chemistry, 298 (2). 101546. p. 101546. ISSN 0021-9258
Bon, RS orcid.org/0000-0003-1733-3680, Wright, DJ, Beech, DJ orcid.org/0000-0002-7683-9422 et al. (1 more author) (2022) Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine. Annual Review of Pharmacology and Toxicology, 62. pp. 427-446. ISSN 0362-1642
PG/19/3/34133
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
PG/19/54/34511
Hurdus, B orcid.org/0000-0001-8149-3449, Munyombwe, T orcid.org/0000-0002-1307-6691, Dondo, TB et al. (6 more authors) (2020) Association of cardiac rehabilitation and health-related quality of life following acute myocardial infarction. Heart. ISSN 1355-6037
Munyombwe, T orcid.org/0000-0002-1307-6691, Dondo, TB, Aktaa, S et al. (7 more authors) (2021) Association of multimorbidity and changes in health-related quality of life following myocardial infarction: a UK multicentre longitudinal patient-reported outcomes study. BMC Medicine, 19 (1). 227. ISSN 1741-7015
Hadanny, A, Shouval, R, Wu, J orcid.org/0000-0001-6093-599X et al. (8 more authors) (2021) Predicting 30-day mortality after ST elevation myocardial infarction: Machine learning- based random forest and its external validation using two independent nationwide datasets. Journal of Cardiology, 78 (5). pp. 439-446. ISSN 0914-5087
Munyombwe, T orcid.org/0000-0002-1307-6691, Hall, M orcid.org/0000-0003-1246-2627, Dondo, TB et al. (6 more authors) (2020) Quality of life trajectories in survivors of acute myocardial infarction: a national longitudinal study. Heart, 106 (1). pp. 33-39. ISSN 1355-6037
Munyombwe, T., Dondo, T.B., Hall, M. orcid.org/0000-0003-1246-2627 et al. (10 more authors) (2024) Corrigendum to: Cohort profile: Evaluation of the Methods and Management of Acute Coronary Events (EMMACE) longitudinal cohort. European Heart Journal - Quality of Care and Clinical Outcomes, 10 (2). p. 189. ISSN 2058-5225
PG/19/68/34614
Szedlak, P., Steele, D.S. orcid.org/0000-0002-1339-784X and Hopkins, P.M. (2023) Cardiac muscle physiology. BJA Education, 23 (9). pp. 350-357. ISSN 2058-5349
PG/19/81/34758
Stewart, L and Turner, NA orcid.org/0000-0002-4957-5433 (2021) Channelling the Force to Reprogram the Matrix: Mechanosensitive Ion Channels in Cardiac Fibroblasts. Cells, 10 (5). 990. ISSN 2073-4409
PG/20/10010
Eyre, B. orcid.org/0000-0001-9261-3776, Shaw, K., Sharp, P. et al. (5 more authors) (2022) The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice. Scientific Reports, 12. 6236. ISSN 2045-2322
PG/21/10322
Farooq, Maryum, A. E. Brown, Louise, Fitzpatrick, Andrew et al. (14 more authors) (2023) Identification of non-ischaemic fibrosis in male veteran endurance athletes, mechanisms and association with premature ventricular beats. Scientific Reports, 13. 14640. ISSN 2045-2322
PG/21/10515
Le Huray, KIP orcid.org/0000-0002-7518-5666, Bunney, TD, Pinotsis, N et al. (2 more authors) (2022) Characterization of the membrane interactions of phospholipase Cγ reveals key features of the active enzyme. Science Advances, 8 (25). eabp9688. ISSN 2375-2548
Prakaash, D orcid.org/0000-0002-2209-9713, Fagnen, C orcid.org/0000-0002-3308-631X, Cook, GP orcid.org/0000-0003-0223-3652 et al. (2 more authors) (2022) Molecular dynamics simulations reveal membrane lipid interactions of the full-length lymphocyte specific kinase Lck. Scientific Reports, 12. 21121. ISSN 2045-2322
Le Huray, KIP orcid.org/0000-0002-7518-5666, Wang, H orcid.org/0000-0002-2281-5679, Sobott, F orcid.org/0000-0001-9029-1865 et al. (1 more author) (2022) Systematic simulation of the interactions of Pleckstrin homology domains with membranes. Science Advances, 8 (27). eabn6992. ISSN 2375-2548
Beech, D.J. orcid.org/0000-0002-7683-9422, Fagnen, C. and Kalli, A.C. (2024) Biological sensing of fluid flow - lessons from PIEZO1. Biophysical Reviews, 16 (6). pp. 871-873. ISSN 1867-2450
PG/21/10595
Yaganoglu, S., Kalyviotis, K. orcid.org/0000-0002-7640-8905, Vagena-Pantoula, C. orcid.org/0000-0002-3591-2267 et al. (15 more authors) (2023) Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications, 14 (1). 4352. ISSN 2041-1723
Yaganoglu, S., Kalyviotis, K. orcid.org/0000-0002-7640-8905, Vagena-Pantoula, C. orcid.org/0000-0002-3591-2267 et al. (15 more authors) (2023) Author Correction: Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi. Nature Communications, 14. 5787. ISSN 2041-1723
Wang, L, Yang, Z, Wang, S et al. (9 more authors) (2022) Substitution of SERCA2 Cys674 accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis. British Journal of Pharmacology, 179 (17). pp. 4423-4439. ISSN 0007-1188
Beech, D.J. orcid.org/0000-0002-7683-9422, Fagnen, C. and Kalli, A.C. (2024) Biological sensing of fluid flow - lessons from PIEZO1. Biophysical Reviews, 16 (6). pp. 871-873. ISSN 1867-2450
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
PG/23/11366
Nakao, Y., Gale, C. orcid.org/0000-0003-4732-382X, Nadarajah, R. orcid.org/0000-0001-9895-9356 et al. (1 more author) (2024) Predicting incident heart failure from population-based nationwide electronic health records: protocol for a model development and validation study. BMJ: British Medical Journal, 14 (1). e073455. ISSN 0959-535X
Nakao, Y.M, Nakao, K., Nadarajah, R. et al. (6 more authors) (2023) Prognosis, characteristics, and provision of care for patients with the unspecified heart failure electronic health record phenotype: a population-based linked cohort study of 95262 individuals. EClinicalMedicine, 63. 102164. ISSN 2589-5370
R/163158-1
Taylor, H., Brown, J., Clavane, E. et al. (3 more authors) (2024) BS53 The role of BACE1 in metabolic dysfunction and cerebrovascular disease. In: Heart. British Cardiovascular Society Annual Conference, ‘Back to the patient’, 03-05 Jun 2024, Manchester, UK. BMJ Publishing Group , a281-a281.
R122753
Richardson, L, Wang, D, Hughes, R et al. (2 more authors) (2022) RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Scientific Reports, 12 (1). 2841. ISSN 2045-2322
RG/03/004
Hethershaw, EL orcid.org/0000-0002-4366-278X, Adamson, PJ, Smith, KA orcid.org/0000-0001-5695-7117 et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933
RG/05/004
Corcoran, D, Young, R, Adlam, D et al. (12 more authors) (2018) Coronary microvascular dysfunction in patients with stable coronary artery disease: The CE-MARC 2 coronary physiology sub-study. International Journal of Cardiology, 266. pp. 7-14. ISSN 0167-5273
RG/11/10/28924
Yang, Z, Kirton, HM, Al-Owais, M et al. (4 more authors) (2017) Epac2-Rap1 signaling regulates reactive oxygen species production and susceptibility to cardiac arrhythmias. Antioxidants and Redox Signaling, 27 (3). pp. 117-132. ISSN 1523-0864
RG/13/1/30042
Tardajos Ayllon, B., Bowden, N., Souilhol, C. et al. (10 more authors) (2025) Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathways. Cardiovascular Research. cvaf024. ISSN 0008-6363
RG/13/3/30104
Bagoly, Z, Ariëns, RAS, Rijken, DC et al. (2 more authors) (2017) Clot Structure and Fibrinolysis in Thrombosis and Hemostasis. BioMed Research International, 2017. ARTN 46451. ISSN 2314-6133
Baker, SR orcid.org/0000-0002-3147-4925, Zabczyk, M, Macrae, FL orcid.org/0000-0002-7092-0422 et al. (3 more authors) (2019) Recurrent venous thromboembolism patients form clots with lower elastic modulus than those with non-recurrent disease. Journal of Thrombosis and Haemostasis, 17 (4). pp. 618-626. ISSN 1538-7933
Domingues, MM, Macrae, FL orcid.org/0000-0002-7092-0422, Duval, C orcid.org/0000-0002-4870-6542 et al. (7 more authors) (2016) Thrombin and fibrinogen γ' impact clot structure by marked effects on intrafibrillar structure and protofibril packing. Blood, 127 (4). pp. 487-495. ISSN 0006-4971
Jolugbo, P and Ariëns, RAS (2021) Thrombus Composition and Efficacy of Thrombolysis and Thrombectomy in Acute Ischemic Stroke. Stroke, 52 (3). pp. 1131-1142. ISSN 0039-2499
Alkarithi, G, Duval, C orcid.org/0000-0002-4870-6542, Shi, Y et al. (2 more authors) (2021) Thrombus Structural Composition in Cardiovascular Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (9). pp. 2370-2383. ISSN 1079-5642
Macrae, FL orcid.org/0000-0002-7092-0422, Duval, C orcid.org/0000-0002-4870-6542, Papareddy, P et al. (13 more authors) (2018) A fibrin biofilm covers blood clots and protects from microbial invasion. Journal of Clinical Investigation, 128 (8). pp. 3356-3368. ISSN 0021-9738
Duval, C orcid.org/0000-0002-4870-6542, Baranauskas, A, Feller, T et al. (14 more authors) (2021) Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences, 118 (27). e2103226118. ISSN 0027-8424
McPherson, HR, Duval, C orcid.org/0000-0002-4870-6542, Baker, SR et al. (10 more authors) (2021) Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis. eLife, 10. e68761. ISSN 2050-084X
RG/16/1/32092
Garg, P orcid.org/0000-0002-5483-169X, Broadbent, DA, Swoboda, PP orcid.org/0000-0001-7162-7079 et al. (14 more authors) (2017) Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 19 (1). ARTN 73. ISSN 1097-6647
Zakkaroff, C orcid.org/0000-0003-3668-8794, Biglands, JD orcid.org/0000-0002-1161-5022, Greenwood, JP orcid.org/0000-0002-2861-0914 et al. (4 more authors) (2018) Patient-specific coronary blood supply territories for quantitative perfusion analysis. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 6 (2). pp. 137-154. ISSN 2168-1163
RG/16/5/32250
Hindle, MS, Spurgeon, BEJ, Cheah, LT et al. (2 more authors) (2021) Multidimensional flow cytometry reveals novel platelet subpopulations in response to prostacyclin. Journal of Thrombosis and Haemostasis, 19 (7). pp. 1800-1812. ISSN 1538-7933
RG/16/6/32233
Steer, EJ, Yang, Z, Al-Owais, MM orcid.org/0000-0001-9122-7873 et al. (3 more authors) (2023) Flecainide induces a sustained countercurrent dependent effect on RyR2 in permeabilized WT ventricular myocytes but not in intact cells. Frontiers in Pharmacology, 14. ISSN 1663-9812
RG/17/11/33042
Beech, DJ and Kalli, AC orcid.org/0000-0001-7156-9403 (2019) Force Sensing by Piezo Channels in Cardiovascular Health and Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 39 (11). pp. 2228-2239. ISSN 1079-5642
Bartoli, F, Debant, M, Chuntharpursat-Bon, E et al. (11 more authors) (2022) Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity. The Journal of clinical investigation. ISSN 0021-9738
Beech, D.J. orcid.org/0000-0002-7683-9422, Fagnen, C. and Kalli, A.C. (2024) Biological sensing of fluid flow - lessons from PIEZO1. Biophysical Reviews, 16 (6). pp. 871-873. ISSN 1867-2450
Deivasikamani, V, Dhayalan, S, Abudushalamu, Y et al. (12 more authors) (2019) Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific Reports, 9. 16876. ISSN 2045-2322
Bartoli, F orcid.org/0000-0001-9487-9551, Bailey, MA orcid.org/0000-0001-5038-1970, Rode, B et al. (23 more authors) (2020) Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload. Circulation, 141 (3). pp. 199-216. ISSN 0009-7322
Shi, J orcid.org/0000-0003-2179-8579, Hyman, AJ orcid.org/0000-0003-0874-6678, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (17 more authors) (2023) PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology, 6. 358. ISSN 2399-3642
Morley, LC, Debant, M, Walker, JJ et al. (2 more authors) (2021) Placental blood flow sensing and regulation in fetal growth restriction. Placenta, 113. pp. 23-28. ISSN 0143-4004
Parsonage, G, Cuthbertson, K, Endesh, N et al. (16 more authors) (2023) Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British Journal of Pharmacology, 180 (16). pp. 2039-2063. ISSN 0007-1188
Endesh, N., Chuntharpursat-Bon, E., Revill, C. et al. (11 more authors) (2023) Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver International, 43 (9). pp. 2026-2038. ISSN 1478-3223
Lichtenstein, L. orcid.org/0000-0003-3900-786X, Cheng, C., Evans, E. et al. (12 more authors) (2024) Lipid regulatory effects of endothelial force sensing. In: Atherosclerosis. 92nd EAS Congress, 26-29 May 2024, Lyon, France. Elsevier .
Caolo, V, Debant, M, Endesh, N et al. (5 more authors) (2019) Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression. [Preprint]
Evans, EL, Povstyan, OV, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (9 more authors) (2020) RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as a mechanism of DHS. Blood. ISSN 0006-4971
Chuntharpursat-Bon, E, Povstyan, OV, Ludlow, MJ et al. (3 more authors) (2019) Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity. [Preprint]
Kinsella, J.A., Debant, M., Parsonage, G. et al. (5 more authors) (2024) Pharmacology of PIEZO1 channels. British Journal of Pharmacology, 181 (23). pp. 4714-4732. ISSN 0007-1188
Morley, LC orcid.org/0000-0002-1109-1396, Debant, M, Gaunt, HJ et al. (2 more authors) (2023) Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies. Reproduction & Fertility, 4 (1). e220100. ISSN 2633-8386
Evans, EL, Cuthbertson, K, Endesh, N et al. (8 more authors) (2018) Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation. British Journal of Pharmacology, 175 (10). pp. 1744-1759. ISSN 0007-1188
Beech, DJ and Xiao, B (2018) Piezo channel mechanisms in health and disease. The Journal of Physiology, 596 (6). pp. 965-967. ISSN 0022-3751
Lichtenstein, L. orcid.org/0000-0003-3900-786X, Cheng, C.W., Bajarwan, M. et al. (14 more authors) (2024) Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids. Science Advances, 10 (39). eadq3075. ISSN 2375-2548
Caolo, V orcid.org/0000-0001-6215-2702, Debant, M, Endesh, N et al. (6 more authors) (2020) Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. eLife, 9. ISSN 2050-084X
Morley, LC, Shi, J, Gaunt, HJ et al. (7 more authors) (2018) Piezo1 channels are mechanosensors in human fetoplacental endothelial cells. Molecular Human Reproduction, 24 (10). pp. 510-520. ISSN 1360-9947
RG/18/11/34036
Feller, T, Duval, C orcid.org/0000-0002-4870-6542, Connell, SDA orcid.org/0000-0003-2500-5724 et al. (1 more author) (2021) FXIIIa-mediated Fibrin γ-chain Crosslinks Are Critical for Fibrin Fiber Stiffness and Resistance to Rupture. In: ISTH 2021 Virtual Congress of the International Society of Thrombosis and Haemostasis, 17-21 Jul 2021, Philadelphia (USA), Virtual.
Shi, Y, Gauer, JS orcid.org/0000-0002-0835-639X, Baker, SR et al. (3 more authors) (2021) Neutrophils can Promote Clotting via FXI and Impact Clot Structure via Neutrophil Extracellular Traps in a Distinctive Manner in vitro. Scientific Reports, 11. 1718. ISSN 2045-2322
Abdul, S, Dekkers, DHW, Ariëns, RAS et al. (3 more authors) (2020) On the localization of the cleavage site in human alpha‐2‐antiplasmin, involved in the generation of the non‐plasminogen binding form. Journal of Thrombosis and Haemostasis. ISSN 1538-7933
Baker, SR, Halliday, G, Ząbczyk, M et al. (5 more authors) (2023) Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation. Communications Medicine, 3. 12. ISSN 2730-664X
Siniarski, A, Baker, SR, Duval, C orcid.org/0000-0002-4870-6542 et al. (4 more authors) (2021) Quantitative analysis of clot density, fibrin fiber radius, and protofibril packing in acute phase myocardial infarction. Thrombosis Research, 205. pp. 110-119. ISSN 0049-3848
Feller, T, Connell, SDA orcid.org/0000-0003-2500-5724 and Ariёns, RAS (2022) Why Fibrin Biomechanical Properties Matter for Haemostasis and Thrombosis. Journal of Thrombosis and Haemostasis, 20 (1). pp. 6-16. ISSN 1538-7933
Feller, T. orcid.org/0000-0002-9137-5881, McPherson, H.R., Connell, S.D. orcid.org/0000-0003-2500-5724 et al. (1 more author) (2024) Fibrinogen αC-region acts as a functional safety latch: Implications for a fibrin biomechanical behaviour model. Acta Biomaterialia, 189. pp. 179-191. ISSN 1742-7061
Duval, C orcid.org/0000-0002-4870-6542, Baranauskas, A, Feller, T et al. (14 more authors) (2021) Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences, 118 (27). e2103226118. ISSN 0027-8424
McPherson, HR, Duval, C orcid.org/0000-0002-4870-6542, Baker, SR et al. (10 more authors) (2021) Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis. eLife, 10. e68761. ISSN 2050-084X
RG/19/10/34506
Souilhol, C., Tardajos Ayllon, B., Li, X. et al. (21 more authors) (2022) JAG1-NOTCH4 mechanosensing drives atherosclerosis. Science Advances, 8 (35). eabo7958. ISSN 2375-2548
X, S. orcid.org/0000-0002-3836-9984, Aitken, C., Mehta, V. orcid.org/0000-0002-5289-5526 et al. (8 more authors) (2024) Controversy in mechanotransduction: the role of endothelial cell-cell junctions in fluid shear stress sensing. Journal of Cell Science, 137 (17). jcs262348. ISSN 0021-9533
RG/F/22/110076
MacGowan, H., Brown, O.I., Drozd, M. et al. (10 more authors) (2025) Comorbidity trajectories before and after the diagnosis of heart failure: a UK Biobank cohort study. European Journal of Heart Failure. ISSN 1388-9842
Jenner, W.J., Brown, O.I., Moore, A. et al. (5 more authors) (2024) Health, Burnout and Wellbeing of UK Cardiology Trainees: Insights from the British Junior Cardiologists’ Association Survey. Heart, 110 (22). pp. 1327-1335. ISSN 1355-6037
Drozd, M. orcid.org/0000-0003-0255-4624, Hamilton, F., Cheng, C.W. et al. (9 more authors) (2024) Plasma MERTK is causally associated with infection mortality. Journal of Infection. 106262. ISSN 0163-4453
Brown, OI, Drozd, M, McGowan, H et al. (13 more authors) (2023) Relationship among diabetes, obesity and cardiovascular disease phenotypes: a UK Biobank cohort study. Diabetes Care. dc230294. ISSN 0149-5992
Brown, O.I., Bridge, K.I., Straw, S. et al. (13 more authors) (2024) Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue. Journal of Visualized Experiments, 206. e66608. ISSN 1940-087X
RG2612/12/15
Smith, GA, Fearnley, GW, Tomlinson, DC et al. (2 more authors) (2015) The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis. Bioscience Reports, 35 (5). e00253. ISSN 0144-8463
RG2659/17/19
Berger, M, Raslan, Z, Aburima, A et al. (7 more authors) (2020) Atherogenic Lipid Stress Induces Platelet Hyperactivity Through CD36-Mediated Hyposensitivity To Prostacyclin-; The Role Of Phosphodiesterase 3A. Haematologica, 105 (3). pp. 808-819. ISSN 0390-6078
RG2668/18/20
Das, A, Kelly, C, Teh, I et al. (17 more authors) (2021) Phenotyping hypertrophic cardiomyopathy using cardiac diffusion magnetic resonance imaging: the relationship between microvascular dysfunction and microstructural changes. European Heart Journal - Cardiovascular Imaging. ISSN 2047-2404
RG2683/19/21
Gallagher, H, Hendrickse, PW, Pereira, MG et al. (1 more author) (2023) Skeletal muscle atrophy, regeneration, and dysfunction in heart failure: Impact of exercise training. Journal of Sport and Health Science, 12 (5). pp. 557-567. ISSN 2095-2546
RG68204 13/EE/0203 A092860
Jones, R.J., De Bie, E.M.D.D., Groves, E. et al. (31 more authors) (2022) Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206 (1). pp. 81-93. ISSN 1073-449X
SBF003/1045
Nazemi, M. and Rainero, E. orcid.org/0000-0003-1402-8701 (2020) Cross-talk between the tumor microenvironment, extracellular matrix, and cell metabolism in cancer. Frontiers in Oncology, 10. 239.
SBF004\1052
Rhodes, C.J., Otero-Núñez, P., Wharton, J. et al. (28 more authors) (2020) Whole blood RNA profiles associated with pulmonary arterial hypertension and clinical outcome. American Journal of Respiratory and Critical Care Medicine, 202 (4). pp. 586-594. ISSN 1073-449X
SI/14/1/30718
Fozzato, A., New, L.E., Griffiths, J.C. et al. (3 more authors) (2023) Manipulating mitochondrial dynamics in the NTS prevents diet-induced deficits in brown fat morphology and glucose uptake. Life Sciences, 328. 121922. ISSN 0024-3205
SS/CH/92005
Huang, H, Vandekeere, S, Kalucka, J et al. (17 more authors) (2017) Role of glutamine and interlinked asparagine metabolism in vessel formation. The EMBO Journal, 36 (16). pp. 2334-2352. ISSN 0261-4189
TAVI
Al Musa, T, Uddin, A, Dobson, LE et al. (7 more authors) (2018) Cardiovascular magnetic resonance assessment of 1st generation CoreValve and 2nd generation Lotus valves. Journal of Interventional Cardiology, 31 (3). pp. 391-399. ISSN 0896-4327
TG/19/1/34451
Solanki, R., Gosling, R., Rammohan, V. et al. (9 more authors) (2021) The importance of three dimensional coronary artery reconstruction accuracy when computing virtual fractional flow reserve from invasive angiography. Scientific Reports, 11. 19694. ISSN 2045-2322
Knight, M., Rammohan, V., Preston, A. et al. (9 more authors) (2020) 113 Potential role of coronary physiology in treating ‘bystander’ disease in patients with ST-elevation myocardial infarction. Heart, 106 (Suppl 2). a93-a94. ISSN 1355-6037
Ghobrial, M. orcid.org/0000-0002-3174-653X, Haley, H., Gosling, R. et al. (29 more authors) (2024) Modelled impact of virtual fractional flow reserve in patients undergoing coronary angiography (VIRTU-4). Heart, 110 (16). pp. 1048-1055. ISSN 1355-6037
Pederzani, G., Czechowicz, K., Ghorab, N. et al. (5 more authors) (2022) The use of digital coronary phantoms for the validation of arterial geometry reconstruction and computation of virtual FFR. Fluids, 7 (6). 201. ISSN 2311-5521
UNIV OF CAMBRIDGE
Hiby, SE, Walker, JJ orcid.org/0000-0002-8922-083X, O'Shaughnessy, KM et al. (4 more authors) (2004) Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success. Journal of Experimental Medicine, 200 (8). pp. 957-965. ISSN 0022-1007
tbc Oct 2017
Huang, H, Vandekeere, S, Kalucka, J et al. (17 more authors) (2017) Role of glutamine and interlinked asparagine metabolism in vessel formation. The EMBO Journal, 36 (16). pp. 2334-2352. ISSN 0261-4189