Items where Funder is Cancer Research UK.

Export as [feed] Atom [feed] RSS
Group by: Grant number | Institution | No Grouping
Jump to: C6971/A17940 | . | 0171-1 | 091002 | 092400/Z/10/Z | 10-17751-99-01-G5 | 105615/Z/14/Z | 12/188/05 | 13/192 | 13052 | 13055 | 142491 | 15002 | 1T01-A321 | 2012-005111-12 | 2012/596 | 204825/Z/16/Z | 24891-03-314 | 261747 | 294004 | 2R01EB018992-05 | 38111 | 4200822156 | 4616 | 641458 | 669771 | 675743; 872860 | 6R01EB018992 | 777682 | 818045 | 952118 | A14923 | A15790 | A17859 | A18080 | A18226 | A19121 | A19272 | A19430 | A23227 | A24939 | A25447 | A28301 | A28832 | A29039 | A29067 | A29212 | Award Ref: 30 | BB/K000306/1 | BB/L023113/1 | BB/M006557/1 | C1010/A2915 | C11071/A20105 | C18027/A13762 | C18803/A7264 | C22090/A7329 | C23065/A11891 | C23434/A23706 | C23434/A9805 | C24098/A9294 | C24461/A12772 | C24461/A23302 | C25425/A27718 | C25574/A24321 | C26253/A16367 | C26441/A8944 | C26441/A9687 | C28106/A9844 | C34080/A16438 | C37059/A11941 | C37059/A12513 | C42785/A17965 | C43420/A17904; C5410/A7315; C5410/A15588 | C43832/A14246 | C44620/A23517 | C47778/A30039 | C50189/A22951 | C5273/A8986 | C5410/A12152 | C55663/A23269 | C57233/A22536/A23770 | C57775/A22182 | C588/A10589 | C588/A4994 | C6003/A10079 | C6003/A15546 | C6003/A3830 | C6003/A6407 | C6003/A7367 | C6003/A7686 | C6228/A12512 | C6228/A5433 | C6228/A5569 | C63579/A26206 | C64904/A27744 | C7775/A14384 | C7775/A7424 | C7845/A10066 | C7845/A17723 | C7852/A19772 | C8175/A7672 | C8216/A11963 | C8216/A6129 | C8216/A8777 | C8525/A21082 | C9267/A25152 | CA101A | CA115 | CH160052 | CRUK 04 05 BUDGET | CRUK 05 06 BUDGET | CRUK-A18349 | DRF-2012-05-201 | DRF-2016-09-084 | DRIKXHAAS | ECMC | EMSG1J3R | EP/P023266/1 | EP/P027938/1 | EP/P51097X/1 | EP/R045291/1 | EP/S001069/1 | EP/V047914/1 | ES/L011891/1 | ES/N00941X/1 | ES/S007164/1 | Fund No IT01 | HEALTH-F4-2010-241669 | L004PhD | L339 | L346 | L354 PA | L367 | L372 | L376PA | L386 | L394 | LPP034 | LPP041 | M14-0138:1 | MAWE1415R61 | MR/K012665/1 | MR/L01629X/1 | MR/M016587/1 | MR/M020606/1; MR/M020606/2 | MR/N021339/1 | MR/N029976/1 | MR/P026206/1 | N/A | NAF\R2\180782 | NCRN CC | NCRN-EORTC-CR-UK LIASION | NIHR 129268 | NIHR Surgical MIC MF | NO EXT REF GIVEN | NON GIVEN | NONE GIVEN | NOT GIVEN | No Ext Ref | No Ext Ref Given | No Ref | No ref given | Not Known | PB-PG-1207-15237 | PCI-32765CLL3003 Ibrutin | PHE | PP015 | PPS WS56 | PROJECT GRANT 12-0023 | RCS REF 08-0843 SUBCONTR | RFPB: PB-PG-0107-12048 | RP-PG-0611-20008 | RP-PG-1209-10013 | RS 8441 Selimetry Trial | S501 | SP2/CHOICES/2010 | SUPAC 004 | TB2017SHEF | TB2017SHEF; TB2O19BAR | TB2O19BAR | TRYMS | TYA CAN COHORT STY G569 | X120 | X160111 | c588/A19167 | ep/k034537/2 | m16-4 | n/a | wm150122
Number of items: 719.

C6971/A17940

Srivastava, T. orcid.org/0000-0002-5961-9348, Chambers, D., Thomas, C. et al. (1 more author) (2019) ECASS health economic feasibility study. Report. ScHARR HEDS Discussion Papers . School of Health and Related Research, University of Sheffield , Sheffield.

.

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

0171-1

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

091002

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

092400/Z/10/Z

Giancane, G, Diggle, CP, Legger, EG et al. (7 more authors) (2015) Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment. Journal of Rheumatology, 42 (11). 2211 - 2214. ISSN 0315-162X

10-17751-99-01-G5

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Steinberg, J, Iles, MM orcid.org/0000-0002-2603-6509, Lee, JY et al. (11 more authors) (2022) Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts. British Journal of Dermatology, 186 (5). pp. 823-834. ISSN 0007-0963

Laskar, R, Ferreiro‐Iglesias, A, Bishop, DT et al. (11 more authors) (2020) Risk factors for melanoma by anatomical site: an evaluation of aetiological heterogeneity. British Journal of Dermatology. ISSN 0007-0963

Law, M, Bishop, DT orcid.org/0000-0002-8752-8785, Lee, JE et al. (78 more authors) (2015) Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nature Genetics, 47 (9). pp. 987-995. ISSN 1061-4036

Muralidhar, S, Filia, A, Nsengimana, J et al. (11 more authors) (2019) Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity. Cancer Research, 79 (23). pp. 5986-5998. ISSN 0008-5472

Bishop, DT, Iles, MM orcid.org/0000-0002-2603-6509, Newton-Bishop, JA et al. (16 more authors) (2018) Abstract 234: Understanding melanoma susceptibility through GWAS of risk phenotypes. In: Cancer Research. AACR Annual Meeting 2018, 14-18 Apr 2018, Chicago, Illinois. American Association for Cancer Research .

Cust, AE, Drummond, M, Kanetsky, PA et al. (18 more authors) (2018) Assessing the incremental contribution of common genomic variants to melanoma risk prediction in two population-based studies. Journal of Investigative Dermatology, 138 (12). pp. 2617-2624. ISSN 0022-202X

Mangantig, E, Iles, MM orcid.org/0000-0002-2603-6509, Newton-Bishop, JA et al. (2 more authors) (2017) Combining Genetic, Transcriptomic and Clinical Variables to Predict Melanoma-specific Survival. In: Genetic Epidemiology. The 2017 Annual Meeting of the International Genetic Epidemiology Society, 09-11 Sep 2017, Cambridge, UK. Wiley , p. 688.

Gu, F, Chen, T-H, Pfeiffer, RM et al. (27 more authors) (2018) Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Human Molecular Genetics, 27 (23). pp. 4145-4156. ISSN 0964-6906

Visconti, A, Duffy, DL, Liu, F et al. (19 more authors) (2018) Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. Nature Communications, 9 (1). 1684. p. 1684. ISSN 2041-1723

Choi, J, Zhang, T, Vu, A et al. (21 more authors) (2019) Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion. Working Paper. Cold Spring Harbor Laboratory (Submitted)

Law, MH, Aoude, LG, Duffy, DL et al. (19 more authors) (2020) Multiplex melanoma families are enriched for polygenic risk. Human Molecular Genetics. ISSN 0964-6906

Duffy, DL, Zhu, G, Li, X et al. (42 more authors) (2018) Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 9. 4774. ISSN 2041-1723

Liyanage, UE, Law, MH, Ong, JS et al. (7 more authors) (2018) Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis. International Journal of Cancer, 143 (3). pp. 508-514. ISSN 0020-7136

Duffy, DL, Zhu, G, Li, X et al. (42 more authors) (2019) Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 10. 299. ISSN 2041-1723

Fang, J, Jia, J, Makowski, M et al. (38 more authors) (2018) Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 9. p. 16159.

Choi, J, Xu, M, Makowski, MM et al. (16 more authors) (2017) A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. Nature Genetics, 49 (9). pp. 1287-1413. ISSN 1061-4036

Harland, M, Petljak, M, Robles-Espinoza, CD et al. (13 more authors) (2016) Germline TERT promoter mutations are rare in familial melanoma. Familial Cancer, 15 (1). pp. 139-144. ISSN 1389-9600

Cust, AE, Drummond, M, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (15 more authors) (2019) Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure. Journal of the European Academy of Dermatology and Venereology, 33 (10). pp. 1874-1885. ISSN 0926-9959

Vuong, K, Armstrong, BK, Drummond, M et al. (12 more authors) (2020) Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines. The British Journal of Dermatology, 182 (5). pp. 1262-1268. ISSN 0007-0963

Nsengimana, J, Laye, J, Filia, A et al. (15 more authors) (2018) β-catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. Journal of Clinical Investigation, 128 (5). pp. 2048-2063. ISSN 0021-9738

Liyanage, UE, Law, MH, Han, X et al. (8 more authors) (2019) Abstract 1592: Genome-wide meta-analysis of keratinocytic cancers identifies 26 novel risk loci. In: AACR Annual Meeting 2019, 29 Mar - 03 Apr 2019, Atlanta, GA, USA.

Dusingize, JC, Olsen, CM, An, J et al. (10 more authors) (2020) Body mass index and height and risk of cutaneous melanoma: Mendelian randomization analyses. International Journal of Epidemiology, 49 (4). pp. 1236-1245. ISSN 0300-5771

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Correction to: Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (5). p. 963. ISSN 0001-6322

Lindstrom, S, Kar, S, Wang, L et al. (25 more authors) (2020) Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions. In: AACR Annual Meeting 2020, 27 Apr - 24 Jun 2020, Philadelphia, PA, USA.

Feng, H, Majumdar, A, Pasaniuc, B et al. (20 more authors) (2020) Cross-cancer cross-tissue Transcriptome-wide Association Study (TWAS) of 11 cancers identifies 56 novel genes. In: AACR Annual Meeting 2020, 27 Apr 2020, Philadelphia, PA, USA.

Olsen, CM, Pandeya, N, Law, MH et al. (7 more authors) (2020) Does polygenic risk influence associations between sun exposure and melanoma?: a prospective cohort analysis. British Journal of Dermatology, 183 (2). pp. 303-310. ISSN 0007-0963

Cardinale, A, Cantalupo, S, Lasorsa, VA et al. (20 more authors) (2021) Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Human Molecular Genetics. ISSN 0964-6906

Chen, H, Majumdar, A, Wang, L et al. (75 more authors) (2021) Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances, 2 (3). 100041. ISSN 2666-2477

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (2). pp. 347-364. ISSN 0001-6322

Xu, M, Mehl, L, Zhang, T et al. (25 more authors) (2021) A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics, 108 (9). pp. 1611-1630. ISSN 0002-9297

Avitabile, M, Succoio, M, Testori, A et al. (25 more authors) (2020) Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Carcinogenesis, 41 (3). pp. 284-295. ISSN 0143-3334

105615/Z/14/Z

Spencer, K orcid.org/0000-0002-6846-4341, Ellis, R, Birch, R orcid.org/0000-0003-1579-1397 et al. (6 more authors) (2017) Caution is required in the implementation of 90-day mortality indicators for radiotherapy in a curative setting: A retrospective population-based analysis of over 16,000 episodes. Radiotherapy and Oncology, 125 (1). pp. 140-146. ISSN 0167-8140

12/188/05

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

13/192

Samson, A orcid.org/0000-0002-3081-7850, Scott, KJ orcid.org/0000-0002-5790-9579, Taggart, D et al. (36 more authors) (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine, 10 (422). eaam7577. ISSN 1946-6234

Taggart, D, Andreou, T, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (7 more authors) (2018) Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking. Proceedings of the National Academy of Sciences of the United States of America, 115 (7). E1540-E1549. ISSN 0027-8424

13052

Painter, D, Barrans, S, Lacy, S et al. (8 more authors) (2019) Cell‐of‐origin in diffuse large B‐cell lymphoma: findings from the UK's population‐based Haematological Malignancy Research Network. British Journal of Haematology, 185 (4). pp. 781-784. ISSN 0007-1048

Sha, C, Barrans, S, Cucco, F et al. (20 more authors) (2019) Molecular high-grade B cell lymphoma: defining a poor risk group requiring different approaches to therapy. Journal of Clinical Oncology, 37 (3). pp. 202-213. ISSN 0732-183X

13055

Shrimpton, J, Care, MA orcid.org/0000-0001-6584-5889, Carmichael, J et al. (7 more authors) (2020) TLR-mediated activation of Waldenström macroglobulinemia B cells reveals an uncoupling from plasma cell differentiation. Blood Advances, 4 (12). pp. 2821-2836. ISSN 2473-9529

142491

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

15002

Sha, C, Barrans, S, Cucco, F et al. (20 more authors) (2019) Molecular high-grade B cell lymphoma: defining a poor risk group requiring different approaches to therapy. Journal of Clinical Oncology, 37 (3). pp. 202-213. ISSN 0732-183X

1T01-A321

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

2012-005111-12

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

2012/596

Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801, Thomas, JD et al. (3 more authors) (2018) Obesity surgery and risk of colorectal and other obesity-related cancers: An English population-based cohort study. Cancer Epidemiology, 53. pp. 99-104. ISSN 1877-7821

Hull, MA orcid.org/0000-0001-7414-1576, Markar, SR and Morris, EJA orcid.org/0000-0002-1075-6544 (2018) Cancer risk after bariatric surgery - is colorectal cancer a special case? Nature reviews. Gastroenterology & hepatology, 15 (11). pp. 635-654. ISSN 1759-5045

204825/Z/16/Z

Rudd, CE, Chanthong, K and Taylor, A orcid.org/0000-0003-2295-2611 (2020) Small Molecule Inhibition of Glycogen Synthase Kinase 3 (GSK-3) Specifically Inhibits the Transcription of Inhibitory Co-Receptor LAG-3 for Enhanced Anti-Tumor Immunity. Cell Reports, 30 (7). pp. 2075-2082. ISSN 2211-1247

Steele, L, Mannion, AJ, Shaw, G et al. (4 more authors) (2021) Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection. iScience, 24 (6). 102555. ISSN 2589-0042

24891-03-314

Law, M, Bishop, DT orcid.org/0000-0002-8752-8785, Lee, JE et al. (78 more authors) (2015) Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nature Genetics, 47 (9). pp. 987-995. ISSN 1061-4036

261747

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

294004

Taggart, D, Andreou, T, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (7 more authors) (2018) Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking. Proceedings of the National Academy of Sciences of the United States of America, 115 (7). E1540-E1549. ISSN 0027-8424

2R01EB018992-05

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

38111

Seymour, M orcid.org/0000-0002-2441-9629 (2019) Choosing the right strategy based on individualized treatment effect predictions: combination versus sequential chemotherapy in patients with metastatic colorectal cancer. Acta Oncologica, 58 (3). pp. 326-333. ISSN 0284-186X

Davidson, M, Chau, I, Cunningham, D et al. (5 more authors) (2017) Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer. World Journal of Gastrointestinal Oncology, 9 (8). pp. 333-340. ISSN 1948-5204

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

4200822156

Howard, DR, Hockaday, A, Brown, JM orcid.org/0000-0002-2719-7064 et al. (6 more authors) (2021) A platform trial in practice: adding a new experimental research arm to the ongoing confirmatory FLAIR trial in chronic lymphocytic leukaemia. Trials, 22 (1). 38. ISSN 1745-6215

Collett, L, Howard, DR orcid.org/0000-0003-3333-9783, Munir, T et al. (11 more authors) (2017) Assessment of ibrutinib plus rituximab in front-line CLL (FLAIR trial): study protocol for a phase III randomised controlled trial. Trials, 18. 387. ISSN 1745-6215

4616

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

641458

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Poźniak, J, Nsengimana, J, Laye, JP et al. (15 more authors) (2019) Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma. Cancer Research, 79 (10). pp. 2684-2696. ISSN 0008-5472

Juraleviciute, M, Pozniak, J, Nsengimana, J et al. (11 more authors) (2020) MX 2 is a novel regulator of cell cycle in melanoma cells. Pigment Cell & Melanoma Research, 33 (3). pp. 446-457. ISSN 1755-1471

Muralidhar, S, Filia, A, Nsengimana, J et al. (11 more authors) (2019) Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity. Cancer Research, 79 (23). pp. 5986-5998. ISSN 0008-5472

Nsengimana, J, Laye, J, Filia, A et al. (15 more authors) (2018) β-catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. Journal of Clinical Investigation, 128 (5). pp. 2048-2063. ISSN 0021-9738

669771

Richards, MW orcid.org/0000-0003-1108-2825, Burgess, S orcid.org/0000-0003-0361-0691, Poon, E et al. (4 more authors) (2016) Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors. Proceedings of the National Academy of Sciences, 113 (48). pp. 13726-13731. ISSN 0027-8424

675743; 872860

Iscaro, A., Jones, C., Forbes, N. et al. (10 more authors) (2022) Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus. Nanomedicine: Nanotechnology, Biology and Medicine, 40. 102506. ISSN 1549-9634

6R01EB018992

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

Martin, JW orcid.org/0000-0002-4450-8127, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, JC orcid.org/0000-0001-9981-5936 et al. (4 more authors) (2020) Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation. Nature Machine Intelligence, 2 (10). pp. 595-606. ISSN 2522-5839

777682

Howard, F. orcid.org/0000-0001-9899-3079, Conner, J., Danson, S. orcid.org/0000-0002-3593-2890 et al. (1 more author) (2022) Inconsistencies in modeling the efficacy of the oncolytic virus HSV1716 reveal potential predictive biomarkers for tolerability. Frontiers in Molecular Biosciences, 9. 889395.

Howard, F.H.N. orcid.org/0000-0001-9899-3079, Kwan, A., Winder, N. et al. (3 more authors) (2022) Understanding immune responses to viruses—do underlying Th1/Th2 cell biases predict outcome? Viruses, 14 (7). 1493.

818045

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

Martin, JW orcid.org/0000-0002-4450-8127, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, JC orcid.org/0000-0001-9981-5936 et al. (4 more authors) (2020) Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation. Nature Machine Intelligence, 2 (10). pp. 595-606. ISSN 2522-5839

952118

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

A14923

Swinson, D, Hingorani, M, Stokes, Z et al. (15 more authors) (2019) Best supportive care (BSC) with or without low-dose chemotherapy (chemo) in frail elderly patients with advanced gastroesophageal cancer (aGOAC): The uncertain randomization of the GO2 phase III trial. In: Journal of Clinical Oncology. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), 31 May - 04 Jun 2019, Chicago, USA. American Society of Clinical Oncology , p. 4051.

Hall, P, Swinson, D, Lord, S et al. (7 more authors) (2019) Chemotherapy for frail and elderly patients (pts) with advanced gastroesophageal cancer (aGOAC): Quality of Life (QoL) results from the GO2 phase III trial. In: 44th ESMO Congress (ESMO 2019), 27 Sep - 01 Oct 2019, Barcelona, Spain.

Hall, PS, Swinson, D, Waters, JS et al. (17 more authors) (2019) Optimizing chemotherapy for frail and elderly patients (pts) with advanced gastroesophageal cancer (aGOAC): The GO2 phase III trial. In: Journal of Clinical Oncology. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), 31 May - 04 Jun 2019, Chicago, USA. American Society of Clinical Oncology .

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

A15790

Howard, DR, Hockaday, A, Brown, JM orcid.org/0000-0002-2719-7064 et al. (6 more authors) (2021) A platform trial in practice: adding a new experimental research arm to the ongoing confirmatory FLAIR trial in chronic lymphocytic leukaemia. Trials, 22 (1). 38. ISSN 1745-6215

Collett, L, Howard, DR orcid.org/0000-0003-3333-9783, Munir, T et al. (11 more authors) (2017) Assessment of ibrutinib plus rituximab in front-line CLL (FLAIR trial): study protocol for a phase III randomised controlled trial. Trials, 18. 387. ISSN 1745-6215

A17859

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

A18080

Perron, G, Jandaghi, P, Solanki, S et al. (15 more authors) (2018) A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes. Cell Reports, 23 (6). pp. 1639-1650. ISSN 2211-1247

Hurst, CD orcid.org/0000-0001-7719-1325, Alder, O orcid.org/0000-0002-7975-9727, Platt, FM et al. (15 more authors) (2017) Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency. Cancer Cell, 32 (5). pp. 701-715. ISSN 1535-6108

A18226

Bosch, MC, Roundhill, EA, Droop, AP et al. (3 more authors) (2018) Abstract 3696: RNAseq of patient-derived cancer stem-like cells and exosomes provides new insights into Ewing's sarcoma. In: AACR Annual Meeting 2018, 14-18 Apr 2018, Chicago, Illinois, USA.

Merugu, S, Chen, L, Gavens, E et al. (13 more authors) (2020) Detection of Circulating and Disseminated Neuroblastoma Cells Using the ImageStream Flow Cytometer for Use as Predictive and Pharmacodynamic Biomarkers. Clinical Cancer Research, 26 (1). pp. 122-134. ISSN 1078-0432

Viprey, VF, Gregory, WM orcid.org/0000-0003-2641-8416, Corrias, MV et al. (12 more authors) (2019) Neuroblastoma mRNAs Predict Outcome in Children With Stage 4 Neuroblastoma: A European HR-NBL1/SIOPEN Study. Journal of Clinical Oncology, 32 (10). pp. 1074-1083. ISSN 0732-183X

Brownhill, SC and Burchill, SA (2017) PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers – Focus on neuroblastoma. Practical Laboratory Medicine, 7. pp. 41-44. ISSN 2352-5517

Corrias, MV, Parodi, S, Tchirkov, A et al. (14 more authors) (2018) Event‐free survival of infants and toddlers enrolled in the HR‐NBL‐1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis. Pediatric Blood and Cancer, 65 (7). e27052. ISSN 1545-5009

A19121

Robinson, M, Christophides, D, Abbott, N et al. (7 more authors) (2017) A Novel Pretrial Contouring Exercise for the UK led PersonaLising Anal cancer radioTherapy dOse (PLATO) Trial. In: Proceedings of the American Society for Radiation Oncology. ASTRO's 59th Annual Meeting, 24-27 Sep 2017, San Diego Convention Center, San Diego California. Elsevier , E181-E182.

Sodergren, SC, Vassiliou, V, Dennis, K et al. (7 more authors) (2015) Systematic Review of the Quality of Life issues associated with Anal Cancer and its treatment with Radiochemotherapy. Supportive Care in Cancer, 23 (12). 3613 - 3623. ISSN 0941-4355

A19272

Cook, G orcid.org/0000-0003-0223-3652, Parrish, C, Yong, K et al. (12 more authors) (2018) Ixazomib, Thalidomide and Dexamethasone Is an Effective and Well Tolerated Re-Induction Regimen Leading to Salvage Autologous Stem Cell Transplantation (sASCT): Results from the Re-Induction Interim Analysis of UK-MRA Myeloma XII (ACCoRD) Trial. In: Blood. ASH 2018 – 60th American Society of Hematology Annual Meeting and Exposition, 01-04 Dec 2018, San Diego, CA. American Society of Hematology .

A19430

Schumann, S, Baquero-Perez, B and Whitehouse, A orcid.org/0000-0003-3866-7110 (2016) Interactions between KSHV ORF57 and the novel human TREX proteins, CHTOP and CIP29. Journal of General Virology, 97. pp. 1904-1910. ISSN 0022-1317

A23227

Robinson, E, Care, M orcid.org/0000-0001-6584-5889, Tooze, R orcid.org/0000-0003-2915-7119 et al. (1 more author) (2018) Salt-Inducible kinases are critical regulators of terminal B-cell differentiation. Journal of Immunology, 200 (1). Supplement 171.3. ISSN 0022-1767

A24939

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

McVeigh, LE, Wijetunga, I, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2019) Development of orthotopic tumour models using ultrasound-guided intrahepatic injection. Scientific Reports, 9. 9904. ISSN 2045-2322

Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801, Thomas, JD et al. (3 more authors) (2018) Obesity surgery and risk of colorectal and other obesity-related cancers: An English population-based cohort study. Cancer Epidemiology, 53. pp. 99-104. ISSN 1877-7821

Taylor, JC orcid.org/0000-0002-2518-5799, Iversen, LH, Burke, D orcid.org/0000-0002-4342-7464 et al. (7 more authors) (2021) Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease, 23 (12). pp. 3152-3161. ISSN 1462-8910

A25447

Boyle, EM, Ashby, C, Tytarenko, R et al. (25 more authors) (2020) BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma. Clinical Cancer Research, 26 (10). pp. 2422-2432. ISSN 1078-0432

Jackson, GH, Pawlyn, C, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (21 more authors) (2021) Carfilzomib, lenalidomide, dexamethasone, and cyclophosphamide (KRdc) as induction therapy for transplant-eligible, newly diagnosed multiple myeloma patients (Myeloma XI+): Interim analysis of an open-label randomised controlled trial. PLOS Medicine, 18 (1). e1003454. ISSN 1549-1277

Weinhold, N, Salwender, HJ, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (15 more authors) (2021) Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma – a meta-analysis of 2,596 trial patients. Haematologica. ISSN 0390-6078

Pearce, J, Swinson, D, Cairns, D orcid.org/0000-0002-2338-0179 et al. (7 more authors) (2022) Frailty and treatment outcome in advanced gastro-oesophageal cancer: An exploratory analysis of the GO2 trial. Journal of Geriatric Oncology, 13 (3). pp. 265-390. ISSN 1879-4068

Morris, TCM, Drake, MB, Kettle, PJ et al. (12 more authors) (2021) How to Simplify the Evaluation of Newly Introduced Chemotherapeutic Interventions in Myeloma. Clinical hematology international, 3 (1). pp. 27-33. ISSN 2590-0048

Caro, J, Cairns, D orcid.org/0000-0002-2338-0179, Menzies, T orcid.org/0000-0003-3896-7228 et al. (11 more authors) (2022) Impact of Etiological Cytogenetic Abnormalities on the Depth of Immunoparesis and Survival in Newly Diagnosed Multiple Myeloma. Clinical Lymphoma Myeloma and Leukemia, 22 (4). E279-E284. ISSN 2152-2650

Allsup, DJ, Craig, Z orcid.org/0000-0001-9930-6648, Cairns, D orcid.org/0000-0002-2338-0179 et al. (13 more authors) (2022) Long-term follow-up of 415 patients with chronic lymphocytic leukemia treated with fludarabine and cyclophosphamide-based chemoimmunotherapy in the frontline ADMIRE and ARCTIC trials: A comprehensive assessment of prognostic factors ADMIRE and ARCTIC trials: A comprehensive assessment of prognostic factors. American Journal of Hematology, 97 (5). E168-E171. ISSN 0361-8609

Gay, F, Jackson, G, Rosiñol, L et al. (28 more authors) (2018) Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis. JAMA Oncology, 4 (10). pp. 1389-1397. ISSN 2374-2437

Hall, PS, Cairns, DA orcid.org/0000-0002-2338-0179 and Seymour, MT orcid.org/0000-0002-2441-9629 (2021) Quantifying and Interpreting Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Cancer Control for Advanced Gastroesophageal Cancer Among an Older Population—Reply. JAMA Oncology, 7 (11). 1725. ISSN 2374-2437

Rana, R, Cockwell, P, Drayson, M et al. (8 more authors) (2020) Renal outcome in patients with newly diagnosed multiple myeloma: results from the UK NCRI Myeloma XI trial. Blood Advances, 4 (22). pp. 5836-5845. ISSN 2473-9529

Royle, K-L and Cairns, DA orcid.org/0000-0002-2338-0179 (2021) The development and validation of prognostic models for overall survival in the presence of missing data in the training dataset: a strategy with a detailed example. Diagnostic and prognostic research, 5 (1). 14. 14-. ISSN 2397-7523

Craig, Z orcid.org/0000-0001-9930-6648, Swain, J, Batman, E et al. (16 more authors) (2020) NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC). BMJ Open, 10 (2). e034527. ISSN 2044-6055

McNamara, MG, Swain, J, Craig, Z et al. (11 more authors) (2019) NET-02: A multi-center, randomised, phase II trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients (pts) with progressive poorly differentiated extra-pulmonary neuroendocrine carcinoma (PD-EP-NEC). In: Journal of Clinical Oncology. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), 31 May - 04 Jun 2019, Chicago, IL, USA. American Society of Clinical Oncology .

Coulson, AB, Royle, K-L orcid.org/0000-0003-0225-1199, Pawlyn, C et al. (22 more authors) (2022) Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial. BMJ Open, 12 (6). e056147. ISSN 2044-6055

A28301

Brown, PJ, Zhong, J, Frood, R orcid.org/0000-0003-2681-9922 et al. (5 more authors) (2019) Prediction of outcome in anal squamous cell carcinoma using radiomic feature analysis of pre-treatment FDG PET-CT. European Journal of Nuclear Medicine and Molecular Imaging, 46 (13). pp. 2790-2799. ISSN 1619-7070

Gilbert, A, Drinkwater, K, McParland, L et al. (7 more authors) (2020) UK national cohort of anal cancer treated with intensity-modulated radiotherapy: One-year oncological and patient-reported outcomes. European Journal of Cancer, 128. pp. 7-16. ISSN 0959-8049

Levick, BA orcid.org/0000-0002-6371-8744, Gilbert, AJ, Spencer, KL orcid.org/0000-0002-6846-4341 et al. (5 more authors) (2020) Time to Surgery Following Short-Course Radiotherapy in Rectal Cancer and its Impact on Postoperative Outcomes. A Population-Based Study Across the English National Health Service, 2009–2014. Clinical Oncology, 32. e46-e52. ISSN 0936-6555

Bach, SP, Gilbert, A orcid.org/0000-0002-9142-1227, Brock, K et al. (20 more authors) (2021) Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study. The Lancet Gastroenterology and Hepatology, 6 (2). pp. 92-105. ISSN 2468-1253

A28832

Frood, R orcid.org/0000-0003-2681-9922, Burton, C, Tsoumpas, C orcid.org/0000-0002-4971-2477 et al. (4 more authors) (2021) Baseline PET/CT imaging parameters for prediction of treatment outcome in Hodgkin and diffuse large B cell lymphoma: a systematic review. European Journal of Nuclear Medicine and Molecular Imaging, 48 (10). pp. 3198-3220. ISSN 1619-7070

Pagett, CJH, Lilley, J, Lindsay, R et al. (2 more authors) (2022) Optimising tumour coverage and organ at risk sparing for hypofractionated re-irradiation in glioblastoma. Physics and Imaging in Radiation Oncology, 21. pp. 84-89. ISSN 2405-6316

Saeed, SU, Taylor, ZA orcid.org/0000-0002-0718-1663, Pinnock, MA et al. (3 more authors) (2020) Prostate Motion Modelling Using Biomechanically-Trained Deep Neural Networks on Unstructured Nodes. In: Lecture Notes in Computer Science. MICCAI 2020: Medical Image Computing and Computer Assisted Intervention – MICCAI 2020, 04-08 Oct 2020, Lima, Peru. Springer Verlag , pp. 650-659. ISBN 9783030597184

Fernandez, S, Beasley, M, Lilley, J et al. (2 more authors) (2021) Establishing a Link Between Commonly Reported Toxicities and Tumour Location in Brain Tumour Patients Treated With Volumetric-modulated Arc Radiotherapy. Clinical Oncology, 33 (1). e97-e98. ISSN 0936-6555

Theophanous, S, Samuel, R, Lilley, J et al. (4 more authors) (2022) Prognostic factors for patients with anal cancer treated with conformal radiotherapy—a systematic review. BMC Cancer, 22 (1). 607. ISSN 1471-2407

Møller, DS, Lutz, CM, Khalil, AA et al. (8 more authors) (2022) Survival benefits for non-small cell lung cancer patients treated with adaptive radiotherapy. Radiotherapy and Oncology. ISSN 0167-8140

A29039

Driscoll, CB, Schuelke, MR, Kottke, T et al. (17 more authors) (2020) APOBEC3B-mediated Corruption of the Tumor Cell Immunopeptidome Induces Heteroclitic Neoepitopes for Cancer Immunotherapy. Nature Communications, 11. 790. ISSN 2041-1723

Liu, JKH, Irvine, AF, Jones, RL et al. (1 more author) (2022) Immunotherapies for hepatocellular carcinoma. Cancer Medicine, 11 (3). pp. 571-591. ISSN 2045-7634

A29067

Nana, G, Mitra, S orcid.org/0000-0002-9378-1496, Watson, H et al. (8 more authors) (2021) Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy. The Journal of nutrition. nxab113. ISSN 0022-3166

Pleguezuelos-Manzano, C, Puschhof, J, Rosendahl Huber, A et al. (25 more authors) (2020) Mutational signature in colorectal cancer caused by genotoxic pks⁺ E. coli. Nature, 580 (7802). pp. 269-273. ISSN 0028-0836

A29212

Ahmed, S orcid.org/0000-0003-4912-746X, Glover, P, Taylor, J et al. (8 more authors) (2021) Comparative analysis of gene expression platforms for cell‐of‐origin classification of diffuse large B‐cell lymphoma shows high concordance. British Journal of Haematology, 192 (3). bjh.17246. pp. 599-604. ISSN 0007-1048

Robinson, E, Care, M orcid.org/0000-0001-6584-5889, Walker, K orcid.org/0000-0002-6694-2979 et al. (3 more authors) (2022) A System for In Vitro Generation of Mature Murine Plasma Cells Uncovers Differential Blimp-1/Prdm1 Promoter Usage. Journal of Immunology, 208 (2). pp. 514-525. ISSN 0022-1767

Award Ref: 30

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

BB/K000306/1

Schumann, S, Baquero-Perez, B and Whitehouse, A orcid.org/0000-0003-3866-7110 (2016) Interactions between KSHV ORF57 and the novel human TREX proteins, CHTOP and CIP29. Journal of General Virology, 97. pp. 1904-1910. ISSN 0022-1317

BB/L023113/1

Burgess, SG orcid.org/0000-0003-0361-0691, Mukherjee, M, Sabir, S orcid.org/0000-0003-0611-6226 et al. (10 more authors) (2018) Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix. EMBO Journal, 37 (8). e97902. ISSN 0261-4189

Mukherjee, M, Sampson, J, Sabir, S et al. (8 more authors) (2017) Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells. In: Molecular Biology of the Cell. ASCB | EMBO 2017 Meeting, 02-06 Dec 2017, Philadelphia, PA. American Society for Cell Biology , T-361-T-362.

BB/M006557/1

Schumann, S, Baquero-Perez, B and Whitehouse, A orcid.org/0000-0003-3866-7110 (2016) Interactions between KSHV ORF57 and the novel human TREX proteins, CHTOP and CIP29. Journal of General Virology, 97. pp. 1904-1910. ISSN 0022-1317

C1010/A2915

Brownhill, SC and Burchill, SA (2017) PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers – Focus on neuroblastoma. Practical Laboratory Medicine, 7. pp. 41-44. ISSN 2352-5517

C11071/A20105

Taylor, A orcid.org/0000-0003-2295-2611 and Rudd, CE (2019) Commentary: Small Molecule Inhibition of PD-1 Transcription is an Effective Alternative to Antibody Blockade in Cancer Therapy. Journal of Immunological Sciences, 3 (1). pp. 9-12. ISSN 2578-3009

Taylor, A orcid.org/0000-0003-2295-2611 and Rudd, CE (2017) Glycogen synthase kinase 3 (GSK-3) inactivation compensates for the lack of CD28 in the priming of CD8+ cytotoxic T-cells: implications for anti-PD-1 immunotherapy. Frontiers in Immunology, 8 (Dec). ARTN 1653. ISSN 1664-3224

Krueger, J, Taylor, A orcid.org/0000-0003-2295-2611, Kazanova, A et al. (4 more authors) (2020) Inhibition of Glycogen Synthase Kinase 3 (GSK-3) synergizes with anti-PD-1 by potentiating tumor-infiltrated CD8+T-cells. In: Cancer Immunology Research. AACR Special Conference on Tumor Immunology and Immunotherapy, 17-20 Nov 2019, Boston, Massachusetts, USA. American Association for Cancer Research Inc. , pp. 60-61.

Taylor, A orcid.org/0000-0003-2295-2611, Rothstein, D and Rudd, CE (2018) Small molecule inhibition of PD-1 transcription is an effective alternative to antibody blockade in cancer therapy. Cancer Research, 78 (3). pp. 706-717. ISSN 0008-5472

Rudd, CE, Chanthong, K and Taylor, A orcid.org/0000-0003-2295-2611 (2020) Small Molecule Inhibition of Glycogen Synthase Kinase 3 (GSK-3) Specifically Inhibits the Transcription of Inhibitory Co-Receptor LAG-3 for Enhanced Anti-Tumor Immunity. Cell Reports, 30 (7). pp. 2075-2082. ISSN 2211-1247

Steele, L, Mannion, AJ, Shaw, G et al. (4 more authors) (2021) Non-redundant activity of GSK-3α and GSK-3β in T cell-mediated tumor rejection. iScience, 24 (6). 102555. ISSN 2589-0042

C18027/A13762

Munir, T, Howard, D orcid.org/0000-0003-3333-9783, McParland, L et al. (10 more authors) (2018) Obinutuzumab as consolidation after chemo-immunotherapy is highly effective in achieving MRD clearance from bone marrow and peripheral blood-Initial results of UK NCRI Phase II/III GALACTIC trial. In: British Journal of Haematology. 58th Annual Scientific Meeting of the British Society for Haematology, 16-18 Apr 2018, Liverpool, UK. Wiley , p. 79.

C18803/A7264

Ahmedzai, SH, Snowden, JA, Ashcroft, AJ et al. (19 more authors) (2019) Patient-Reported Outcome Results From the Open-Label, Randomized Phase III Myeloma X Trial Evaluating Salvage Autologous Stem-Cell Transplantation in Relapsed Multiple Myeloma. Journal of Clinical Oncology, 37 (19). pp. 1617-1628. ISSN 0732-183X

C22090/A7329

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

C23065/A11891

DeFilipp, Z., Duarte, R.F., Snowden, J.A. et al. (34 more authors) (2016) Metabolic syndrome and cardiovascular disease following hematopoietic cell transplantation: screening and preventive practice recommendations from CIBMTR and EBMT. Bone Marrow Transplantation. ISSN 0268-3369

Swain, J, Smith, I, Smith, A et al. (3 more authors) (2015) TRYMS: The ethical and practical considerations of a double-blind placebo controlled randomised clinical trial. In: 3rd International Clinical Trials Methodology Conference, 16-17 Nov 2015, Glasgow, UK. (Unpublished)

Smith, I, Swain, J, Marshall, HC et al. (4 more authors) (2015) Testosterone Replacement in Young Male cancer Survivors (TRYMS) – pragmatic adaptation of trial design for a trial struggling with recruitment. In: 3rd International Clinical Trials Methodology Conference, 16-17 Nov 2015, Glasgow. (Unpublished)

Walsh, JS, Marshall, H orcid.org/0000-0003-0944-0152, Smith, IL et al. (9 more authors) (2019) Testosterone replacement in young male cancer survivors: A 6-month double-blind randomised placebo-controlled trial. PLOS Medicine, 16 (11). e1002960. ISSN 1549-1277

C23434/A23706

Downing, A orcid.org/0000-0002-0335-7801, Hall, P, Birch, R orcid.org/0000-0003-1579-1397 et al. (6 more authors) (2021) Data Resource Profile: The COloRECTal cancer data repository (CORECT-R). International Journal of Epidemiology, 50 (5). 1418-1418k. ISSN 0300-5771

Araghi, M, Soerjomataram, I, Jenkins, M et al. (4 more authors) (2019) Global trends in colorectal cancer mortality: projections to the year 2035. International Journal of Cancer, 144 (12). pp. 2992-3000. ISSN 0020-7136

Birch, R orcid.org/0000-0003-1579-1397, Burr, N, Subramanian, V et al. (8 more authors) (2022) IBD-associated CRC epidemiology and outcomes: an English population-based study. The American Journal of Gastroenterology. ISSN 0002-9270

Morris, E orcid.org/0000-0002-1075-6544 and Treasure, T (2017) If a picture is worth a thousand words, take a good look at the picture: survival after liver metastasectomy for colorectal cancer. Cancer Epidemiology, 49. pp. 152-155. ISSN 1877-7821

Syriopoulou, E, Morris, E orcid.org/0000-0002-1075-6544, Finan, PJ et al. (2 more authors) (2019) Understanding the impact of socioeconomic differences in colorectal cancer survival: potential gain in life-years. British Journal of Cancer, 120 (11). pp. 1052-1058. ISSN 0007-0920

Rutter, MD, Beintaris, I, Valori, R et al. (19 more authors) (2018) World Endoscopy Organization Consensus Statements on Post-Colonoscopy and Post-Imaging Colorectal Cancer. Gastroenterology, 155 (3). 909-925.e3. ISSN 0016-5085

Sjoquist, KM, Renfro, LA, Simes, RJ et al. (31 more authors) (2017) Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 10 (6). djx253. ISSN 0027-8874

Birch, RJ orcid.org/0000-0003-1579-1397, Taylor, JC orcid.org/0000-0002-2518-5799, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2019) Rectal cancer in old age –is it appropriately managed? Evidence from population-based analysis of routine data across the English national health service. European Journal of Surgical Oncology, 45 (7). pp. 1196-1204. ISSN 0748-7983

Birch, R orcid.org/0000-0003-1579-1397, Taylor, J orcid.org/0000-0002-2518-5799, Downing, A orcid.org/0000-0002-0335-7801 et al. (3 more authors) (2018) The management of rectal cancer in older patients in England - a retrospective population based study a patients diagnosed between April 2009 and December 2014. In: European Journal of Surgical Oncology. 38th European Society of Surgical Oncology Congress (ESSO 38), 10-12 Oct 2018, Budapest, Hungary. ESSO .

Battisti, NML, Wallington, M, Ring, A et al. (12 more authors) (2018) Is age a barrier to chemotherapy? Rates of treatment in older patients with breast, colon or lung cancer in England in 2014: A national registry study. In: Annals of Oncology. 43rd ESMO Congress (ESMO 2018), 19-23 Oct 2018, Munich, Germany. Oxford University Press .

Downing, A orcid.org/0000-0002-0335-7801, Glaser, AW, Finan, PJ et al. (7 more authors) (2019) Functional Outcomes and Health-Related Quality of Life After Curative Treatment for Rectal Cancer: A Population-Level Study in England. International Journal of Radiation Oncology*Biology*Physics, 103 (5). pp. 1132-1142. ISSN 0360-3016

Levick, BA orcid.org/0000-0002-6371-8744, Gilbert, AJ, Spencer, KL orcid.org/0000-0002-6846-4341 et al. (5 more authors) (2020) Time to Surgery Following Short-Course Radiotherapy in Rectal Cancer and its Impact on Postoperative Outcomes. A Population-Based Study Across the English National Health Service, 2009–2014. Clinical Oncology, 32. e46-e52. ISSN 0936-6555

Wilkins, E, Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2020) Evidence from big data in obesity research: International case studies. International Journal of Obesity, 44 (5). pp. 1028-1040. ISSN 0307-0565

Hull, MA orcid.org/0000-0001-7414-1576, Markar, SR and Morris, EJA orcid.org/0000-0002-1075-6544 (2018) Cancer risk after bariatric surgery - is colorectal cancer a special case? Nature reviews. Gastroenterology & hepatology, 15 (11). pp. 635-654. ISSN 1759-5045

Taylor, JC orcid.org/0000-0002-2518-5799, Swinson, D, Seligmann, JF et al. (8 more authors) (2021) Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: can a regional intervention promote national change? International Journal of Cancer, 148 (4). pp. 845-856. ISSN 0020-7136

Morris, EJA, Goldacre, R, Spata, E et al. (18 more authors) (2021) Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study. The Lancet Gastroenterology & Hepatology. ISSN 2468-1253

Fenton, HM orcid.org/0000-0001-7824-2614, Finan, PJ, Milton, R et al. (4 more authors) (2020) National variation in pulmonary metastasectomy for colorectal cancer. Colorectal Disease. ISSN 1462-8910

Brown, PJ, Rossington, H orcid.org/0000-0002-4570-2730, Taylor, J orcid.org/0000-0002-2518-5799 et al. (5 more authors) (2019) Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice. European Radiology, 29 (9). pp. 5121-5128. ISSN 0938-7994

Fenton, HM orcid.org/0000-0001-7824-2614, Taylor, JC orcid.org/0000-0002-2518-5799, Lodge, JPA et al. (4 more authors) (2019) Variation in the Use of Resection for Colorectal Cancer Liver Metastases. Annals of Surgery, 270 (5). pp. 892-898. ISSN 0003-4932

Burr, NE orcid.org/0000-0003-1988-2982, Derbyshire, E, Taylor, J orcid.org/0000-0002-2518-5799 et al. (6 more authors) (2019) Variation in post-colonoscopy colorectal cancer across colonoscopy providers in English National Health Service: population based cohort study. BMJ, 367. l6090. ISSN 1759-2151

Taylor, JC orcid.org/0000-0002-2518-5799, Iversen, LH, Burke, D orcid.org/0000-0002-4342-7464 et al. (7 more authors) (2021) Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease, 23 (12). pp. 3152-3161. ISSN 1462-8910

C23434/A9805

Spencer, KL, Morris, E, Dugdale, E et al. (5 more authors) (2015) 30 day mortality in adult palliative radiotherapy - A retrospective population based study of 14,972 treatment episodes. Radiotherapy and Oncology, 115 (2). 264 - 271. ISSN 0167-8140

Downing, A orcid.org/0000-0002-0335-7801, Morris, EJA orcid.org/0000-0002-1075-6544, Corrigan, N et al. (13 more authors) (2017) High hospital research participation and improved colorectal cancer survival outcomes: a population-based study. Gut, 66 (1). pp. 89-96. ISSN 0017-5749

Morris, EJA, Finan, PJ, Spencer, K et al. (7 more authors) (2016) Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service. Clinical Oncology, 28 (8). pp. 522-531. ISSN 0936-6555

C24098/A9294

Birch, RJ, Morris, EJA, Stark, DP et al. (4 more authors) (2014) Geographical Factors Affecting the Admission of Teenagers and Young Adults to Age-Specialist Inpatient Cancer Care in England. Journal of Adolescent and Young Adult Oncology, 3 (1). 28 - 36 (9). ISSN 2156-5333

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

C24461/A12772

Burgess, SG orcid.org/0000-0003-0361-0691, Mukherjee, M, Sabir, S orcid.org/0000-0003-0611-6226 et al. (10 more authors) (2018) Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix. EMBO Journal, 37 (8). e97902. ISSN 0261-4189

Burgess, SG orcid.org/0000-0003-0361-0691, Oleksy, A, Cavazza, T et al. (4 more authors) (2016) Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain. Open Biology, 6 (7). 160089. ISSN 2046-2441

Colombano, G, Caldwell, JJ, Matthews, TP et al. (18 more authors) (2019) Binding to an unusual inactive kinase conformation by highly selective inhibitors of inositol-requiring enzyme 1a kinase-endoribonuclease. Journal of Medicinal Chemistry, 62 (5). pp. 2447-2465. ISSN 0022-2623

Concilio, MG, Fielding, AJ, Bayliss, RWA orcid.org/0000-0003-0604-2773 et al. (1 more author) (2016) Density functional theory studies of MTSL nitroxide side chain conformations attached to an activation loop. Theoretical Chemistry Accounts: Theory, Computation, and Modeling, 135 (97). ISSN 1432-881X

Burgess, SG, Grazia Concilio, M, Bayliss, R orcid.org/0000-0003-0604-2773 et al. (1 more author) (2016) Detection of Ligand-induced Conformational Changes in the Activation Loop of Aurora-A Kinase by PELDOR Spectroscopy. ChemistryOpen, 5 (6). pp. 531-534.

Chavali, PL, Stojic, L, Meredith, LW et al. (13 more authors) (2017) Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science, 357 (6346). pp. 83-88. ISSN 0036-8075

Coxon, CR, Wong, C, Bayliss, RWA orcid.org/0000-0003-0604-2773 et al. (14 more authors) (2017) Structure-guided design of purine-based probes for selective Nek2 inhibition. Oncotarget, 8 (12). pp. 19089-19124. ISSN 1949-2553

Bachmann, G, Richards, MW, Winter, A et al. (3 more authors) (2016) A closed conformation of the Caenorhabditis elegans separase-securin complex. Open Biology, 6 (4). ISSN 2046-2441

McIntyre, PJ, Collins, PM, Vrzal, L et al. (11 more authors) (2017) Characterization of three druggable hot-spots in the Aurora-A/TPX2 interaction using biochemical, biophysical and fragment-based approaches. ACS Chemical Biology, 12 (11). pp. 2906-2914. ISSN 1554-8929

Richards, MW orcid.org/0000-0003-1108-2825, Burgess, S orcid.org/0000-0003-0361-0691, Poon, E et al. (4 more authors) (2016) Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors. Proceedings of the National Academy of Sciences, 113 (48). pp. 13726-13731. ISSN 0027-8424

C24461/A23302

Burgess, SG orcid.org/0000-0003-0361-0691, Mukherjee, M, Sabir, S orcid.org/0000-0003-0611-6226 et al. (10 more authors) (2018) Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix. EMBO Journal, 37 (8). e97902. ISSN 0261-4189

Mukherjee, M, Sampson, J, Sabir, S et al. (8 more authors) (2017) Mitotic phosphorylation of Hsp72 uncouples ATP binding from substrate release and clusters amplified centrosomes in cancer cells. In: Molecular Biology of the Cell. ASCB | EMBO 2017 Meeting, 02-06 Dec 2017, Philadelphia, PA. American Society for Cell Biology , T-361-T-362.

Matheson, CJ, Coxon, CR, Bayliss, R orcid.org/0000-0003-0604-2773 et al. (13 more authors) (2020) 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase. RSC Medicinal Chemistry, 11 (6). pp. 707-731. ISSN 2632-8682

O'Regan, L, Barone, G, Adib, R et al. (10 more authors) (2020) EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. Journal of Cell Science. jcs.241505. jcs.241505-jcs.241505. ISSN 0021-9533

Lucken, K, O'Regan, L, Choi, J et al. (5 more authors) (2022) EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research, 20 (6). pp. 854-866. ISSN 1541-7786

Sabir, SR orcid.org/0000-0003-0611-6226, Yeoh, S, Jackson, G et al. (1 more author) (2017) EML4-ALK variants: biological and molecular properties, and the implications for patients. Cancers, 9 (9). 118. ISSN 2072-6694

Sampson, J orcid.org/0000-0002-0147-6014, Ju, H-M, Song, J-Y et al. (3 more authors) (2022) A Polytherapy Strategy Using Vincristine and ALK Inhibitors to Sensitise EML4-ALK-Positive NSCLC. Cancers, 14 (3). 779. ISSN 2072-6694

McIntyre, PJ, Collins, PM, Vrzal, L et al. (11 more authors) (2017) Characterization of three druggable hot-spots in the Aurora-A/TPX2 interaction using biochemical, biophysical and fragment-based approaches. ACS Chemical Biology, 12 (11). pp. 2906-2914. ISSN 1554-8929

C25425/A27718

Ryan, EL, Shelford, J, Massam-Wu, T et al. (2 more authors) (2021) Defining endogenous TACC3–chTOG–clathrin–GTSE1 interactions at the mitotic spindle using induced relocalization. Journal of Cell Science, 134 (3). jcs255794. ISSN 0021-9533

C25574/A24321

Howard, F. orcid.org/0000-0001-9899-3079, Conner, J., Danson, S. orcid.org/0000-0002-3593-2890 et al. (1 more author) (2022) Inconsistencies in modeling the efficacy of the oncolytic virus HSV1716 reveal potential predictive biomarkers for tolerability. Frontiers in Molecular Biosciences, 9. 889395.

Howard, F.H.N. orcid.org/0000-0001-9899-3079, Kwan, A., Winder, N. et al. (3 more authors) (2022) Understanding immune responses to viruses—do underlying Th1/Th2 cell biases predict outcome? Viruses, 14 (7). 1493.

Iscaro, A., Jones, C., Forbes, N. et al. (10 more authors) (2022) Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus. Nanomedicine: Nanotechnology, Biology and Medicine, 40. 102506. ISSN 1549-9634

C26253/A16367

Taggart, D, Andreou, T, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (7 more authors) (2018) Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking. Proceedings of the National Academy of Sciences of the United States of America, 115 (7). E1540-E1549. ISSN 0027-8424

C26441/A8944

Hutchins, GGA orcid.org/0000-0002-1707-4415, Davarzani, N, West, NP orcid.org/0000-0002-0346-6709 et al. (8 more authors) (2018) Defining the Clinical Value of Pathological Lymph Node Status and Primary Tumour Regression Grading Following Neoadjuvant Therapy in Oesophageal Cancer: Results from the MRC OE02 Trial. In: Journal of Pathology. Maastricht Pathology 2018: 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht, the Netherlands. Wiley , S16-S16.

Kloft, M, Ruisch, J, Raghuram, G et al. (2 more authors) (2018) Largest Negative Lymph Node Diameter: A Novel Predictor of Good Prognosis in Patients with Oesophageal Cancer. In: Journal of Pathology. Maastricht Pathology 2018: 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht, the Netherlands. Wiley , S30-S30.

Hale, MD, Nankivell, M, Hutchins, GG et al. (11 more authors) (2016) Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma –results from the UK MRC OE02 trial. Oncotarget, 7 (47). pp. 77565-77575. ISSN 1949-2553

C26441/A9687

Athauda, A, Nankivell, M, Langley, RE et al. (6 more authors) (2020) Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). European Journal of Cancer, 137. pp. 45-56. ISSN 0959-8049

C28106/A9844

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

C34080/A16438

Birch, RJ orcid.org/0000-0003-1579-1397, Taylor, JC orcid.org/0000-0002-2518-5799, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2019) Rectal cancer in old age –is it appropriately managed? Evidence from population-based analysis of routine data across the English national health service. European Journal of Surgical Oncology, 45 (7). pp. 1196-1204. ISSN 0748-7983

Birch, R orcid.org/0000-0003-1579-1397, Taylor, J orcid.org/0000-0002-2518-5799, Downing, A orcid.org/0000-0002-0335-7801 et al. (3 more authors) (2018) The management of rectal cancer in older patients in England - a retrospective population based study a patients diagnosed between April 2009 and December 2014. In: European Journal of Surgical Oncology. 38th European Society of Surgical Oncology Congress (ESSO 38), 10-12 Oct 2018, Budapest, Hungary. ESSO .

Battisti, NML, Wallington, M, Ring, A et al. (12 more authors) (2018) Is age a barrier to chemotherapy? Rates of treatment in older patients with breast, colon or lung cancer in England in 2014: A national registry study. In: Annals of Oncology. 43rd ESMO Congress (ESMO 2018), 19-23 Oct 2018, Munich, Germany. Oxford University Press .

Spencer, K orcid.org/0000-0002-6846-4341, Ellis, R, Birch, R orcid.org/0000-0003-1579-1397 et al. (6 more authors) (2017) Caution is required in the implementation of 90-day mortality indicators for radiotherapy in a curative setting: A retrospective population-based analysis of over 16,000 episodes. Radiotherapy and Oncology, 125 (1). pp. 140-146. ISSN 0167-8140

C37059/A11941

Burghel, GJ, Hurst, CD, Watson, CM et al. (4 more authors) (2015) Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms. BioMed Research International, 2015. 478017. ISSN 2314-6133

C37059/A12513

O'Shea, SJ, Merchant, W, Laye, J et al. (5 more authors) (2017) Transcriptomic profiling the microenvironment in primary melanoma. Pigment Cell and Melanoma Research, 30 (1). p. 127. ISSN 1755-148X

C42785/A17965

Sestak, I, Smith, SG orcid.org/0000-0003-1983-4470, Howell, A et al. (2 more authors) (2018) Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II. Annals of Oncology, 29 (2). pp. 504-509. ISSN 0923-7534

Sestak, I, Smith, S orcid.org/0000-0003-1983-4470, Sleeth, M et al. (2 more authors) (2018) Participant-reported symptoms as predictors of long-term adherence of endocrine therapy in the International breast cancer intervention studies 2 (IBIS-2). In: Cancer Research. 2017 San Antonio Breast Cancer Symposium, 05-09 Dec 2017, San Antonio, Texas. American Association for Cancer Research .

Hackett, J, Thorneloe, R orcid.org/0000-0002-7522-221X, Side, L et al. (4 more authors) (2018) Uptake of breast cancer preventive therapy in the UK: results from a multicentre prospective survey and qualitative interviews. Breast Cancer Research and Treatment, 170 (3). pp. 633-640. ISSN 0167-6806

Smith, SG orcid.org/0000-0003-1983-4470, Beard, E, McGowan, JA et al. (5 more authors) (2018) The development of a tool to assess beliefs about mythical causes of cancer: the Cancer Awareness Measure Mythical Causes Scale. BMJ Open, 8 (12). e022825. ISSN 2044-6055

Noonan, S, Pasa, A, Fontana, V et al. (6 more authors) (2018) A survey among breast cancer specialists on the low uptake of therapeutic prevention with tamoxifen or raloxifene. Cancer Prevention Research, 11 (1). pp. 38-43. ISSN 1940-6207

C43420/A17904; C5410/A7315; C5410/A15588

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

C43832/A14246

Wasson, CW, Morgan, EL, Muller, M orcid.org/0000-0002-2878-464X et al. (4 more authors) (2017) Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle. Oncotarget, 8 (61). pp. 103581-103600. ISSN 1949-2553

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

C44620/A23517

Stevens, C, Vrinten, C, Smith, SG orcid.org/0000-0003-1983-4470 et al. (2 more authors) (2019) Acceptability of receiving lifestyle advice at cervical, breast and bowel cancer screening. Preventive Medicine, 120. pp. 19-25. ISSN 0091-7435

Hall, LH, Thorneloe, R, Rodriguez-Lopez, R et al. (7 more authors) (2021) Delivering brief physical activity interventions in primary care: a systematic review of the prevalence, and factors associated with delivery, receipt, and patient receptivity. British Journal of General Practice. ISSN 0960-1643

Claire, S, Smith, SG, Quaife, SL et al. (3 more authors) (2019) Interest in lifestyle advice at lung cancer screening: Determinants and preferences. Lung Cancer, 128. pp. 1-5. ISSN 0169-5002

Stevens, C, Smith, SG orcid.org/0000-0003-1983-4470, Vrinten, C et al. (2 more authors) (2019) Lifestyle changes associated with participation in colorectal cancer screening: Prospective data from the English Longitudinal Study of Ageing. Journal of Medical Screening, 26 (2). pp. 84-91. ISSN 0969-1413

C47778/A30039

Bourn, M, Batchelor, DVB orcid.org/0000-0001-6489-9578, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2020) Organ on chip models for the evaluation of microbubble based therapeutic delivery. In: Proceedings of Microfluidics, BioMEMS, and Medical Microsystems XVIII. Microfluidics, BioMEMS, and Medical Microsystems XVIII, 01-06 Feb 2020, San Francisco, California, USA. Society of Photo-optical Instrumentation Engineers . ISBN 9781510632332

C50189/A22951

Samson, A orcid.org/0000-0002-3081-7850, Scott, KJ orcid.org/0000-0002-5790-9579, Taggart, D et al. (36 more authors) (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine, 10 (422). eaam7577. ISSN 1946-6234

Jennings, VA, Scott, GB orcid.org/0000-0003-0021-9400, Rose, AMS et al. (13 more authors) (2019) Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition. Molecular Therapy, 27 (6). pp. 1139-1152. ISSN 1525-0016

C5273/A8986

McVeigh, LE, Wijetunga, I, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2019) Development of orthotopic tumour models using ultrasound-guided intrahepatic injection. Scientific Reports, 9. 9904. ISSN 2045-2322

Giancane, G, Diggle, CP, Legger, EG et al. (7 more authors) (2015) Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment. Journal of Rheumatology, 42 (11). 2211 - 2214. ISSN 0315-162X

C5410/A12152

Woll, P., Gaunt, P., Danson, S. et al. (8 more authors) (2022) Olaparib as maintenance treatment in patients with chemosensitive small cell lung cancer (STOMP) : a randomised, double-blind, placebo-controlled phase II trial. Lung Cancer, 171. pp. 26-33. ISSN 0169-5002

C55663/A23269

Brownlie, RJ orcid.org/0000-0003-4897-1044, Wright, D, Zamoyska, R et al. (1 more author) (2019) Deletion of PTPN22 improves effector and memory CD8+ T cell responses to tumors. JCI Insight, 4 (16). e127847. ISSN 2379-3708

Brownlie, RJ, Zamoyska, R and Salmond, RJ orcid.org/0000-0002-1807-1056 (2018) Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22. Immunology, 154 (3). pp. 377-382. ISSN 0019-2805

Brownlie, RJ orcid.org/0000-0003-4897-1044, Garcia, C, Ravasz, M et al. (3 more authors) (2017) Resistance to TGFβ suppression and improved anti-tumor responses in CD8⁺ T cells lacking PTPN22. Nature Communications, 8. 1343. ISSN 2041-1723

Hope, HC, Pickersgill, G, Ginefra, P et al. (3 more authors) (2022) TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8+ T cells. Frontiers in Immunology, 13. 913184. ISSN 1664-3224

Carrasco Hope, H and Salmond, RJ orcid.org/0000-0002-1807-1056 (2019) Targeting the tumour microenvironment and T cell metabolism for effective cancer immunotherapy. European Journal of Immunology, 49 (8). pp. 1147-1152. ISSN 0014-2980

Salmond, RJ orcid.org/0000-0002-1807-1056 (2018) mTOR Regulation of Glycolytic Metabolism in T Cells. Frontiers in Cell and Developmental Biology, 6. 122. ISSN 2296-634X

Hope, HC, Brownlie, RJ orcid.org/0000-0003-4897-1044, Fife, CM et al. (3 more authors) (2021) Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation. JCI Insight, 6 (9). ISSN 2379-3708

C57233/A22536/A23770

Ladbury, JE orcid.org/0000-0002-6328-7200 (2019) Receptor Tyrosine Kinase Signalling in the Absence of Kinase Activity and Cancer of Non-Genetic Origin. In: The Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S8-S8.

C57775/A22182

Okan, Y orcid.org/0000-0001-7963-1363, Garcia-Retamero, R, Cokely, ET et al. (1 more author) (2018) Biasing and debiasing health decisions with bar graphs: Costs and benefits of graph literacy. Quarterly Journal of Experimental Psychology, 71 (12). pp. 2506-2519. ISSN 1747-0218

Okan, Y orcid.org/0000-0001-7963-1363, Petrova, D, Smith, SG orcid.org/0000-0003-1983-4470 et al. (2 more authors) (2019) How Do Women Interpret the NHS Information Leaflet about Cervical Cancer Screening? Medical Decision Making, 39 (7). pp. 738-754. ISSN 0272-989X

Okan, Y orcid.org/0000-0001-7963-1363, Smith, SG and Bruine de Bruin, W orcid.org/0000-0002-1601-789X (2019) How is cervical cancer screening information communicated in UK websites? A cross-sectional analysis of content and quantitative presentation formats. BMJ Open, 9. e029551. ISSN 2044-6055

Okan, Y orcid.org/0000-0001-7963-1363, Stone, ER and Bruine de Bruin, W orcid.org/0000-0002-1601-789X (2018) Designing Graphs that Promote Both Risk Understanding and Behavior Change. Risk Analysis, 38 (5). pp. 929-946. ISSN 0272-4332

Okan, Y orcid.org/0000-0001-7963-1363, Stone, ER, Parillo, J et al. (2 more authors) (2020) Probability Size Matters: The Effect of Foreground‐Only versus Foreground+Background Graphs on Risk Aversion Diminishes with Larger Probabilities. Risk Analysis, 40 (4). pp. 771-788. ISSN 0272-4332

C588/A10589

Del Castillo Velasco-Herrera, M, Van der Weyden, L, Nsengimana, J et al. (6 more authors) (2018) Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis. Molecular Oncology, 12 (2). pp. 239-255. ISSN 1574-7891

Rogers, Z, Elliott, F, Kasparian, NA et al. (3 more authors) (2016) Psychosocial, clinical and demographic features related to worry in patients with melanoma. Melanoma Research, 26 (5). pp. 497-504. ISSN 0960-8931

Chubb, D, Broderick, P, Dobbins, SE et al. (12 more authors) (2016) Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. Nature Communications, 7. 11883. ISSN 2041-1723

Litchfield, K, Loveday, C, Levy, M et al. (9 more authors) (2018) Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene. European Urology, 73 (6). pp. 828-831. ISSN 0302-2838

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Law, M, Bishop, DT orcid.org/0000-0002-8752-8785, Lee, JE et al. (78 more authors) (2015) Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nature Genetics, 47 (9). pp. 987-995. ISSN 1061-4036

Harland, M, Petljak, M, Robles-Espinoza, CD et al. (13 more authors) (2016) Germline TERT promoter mutations are rare in familial melanoma. Familial Cancer, 15 (1). pp. 139-144. ISSN 1389-9600

Nsengimana, J, Laye, J, Filia, A et al. (15 more authors) (2018) β-catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. Journal of Clinical Investigation, 128 (5). pp. 2048-2063. ISSN 0021-9738

C588/A4994

Metri, R, Mohan, A, Nsengimana, J et al. (5 more authors) (2017) Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach. Scientific Reports, 7. 17314. ISSN 2045-2322

Filia, A, Droop, A, Harland, M et al. (10 more authors) (2019) High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material. Scientific Reports, 9 (1). ARTN: 8908. ISSN 2045-2322

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Muralidhar, S, Filia, A, Nsengimana, J et al. (11 more authors) (2019) Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity. Cancer Research, 79 (23). pp. 5986-5998. ISSN 0008-5472

Cust, AE, Drummond, M, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (15 more authors) (2019) Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure. Journal of the European Academy of Dermatology and Venereology, 33 (10). pp. 1874-1885. ISSN 0926-9959

Vuong, K, Armstrong, BK, Drummond, M et al. (12 more authors) (2020) Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines. The British Journal of Dermatology, 182 (5). pp. 1262-1268. ISSN 0007-0963

Nsengimana, J, Laye, J, Filia, A et al. (15 more authors) (2018) β-catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. Journal of Clinical Investigation, 128 (5). pp. 2048-2063. ISSN 0021-9738

C6003/A10079

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

C6003/A15546

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

C6003/A3830

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Salem, ME, Yin, J, Weinberg, BA et al. (18 more authors) (2018) Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. European Journal of Cancer, 103. pp. 205-213. ISSN 0959-8049

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

C6003/A6407

Sjoquist, KM, Renfro, LA, Simes, RJ et al. (31 more authors) (2017) Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 10 (6). djx253. ISSN 0027-8874

Sjoquist, KM, Renfro, LA, Simes, RJ et al. (31 more authors) (2017) Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 10 (6). djx253. ISSN 0027-8874

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Bosch, LJW, Trooskens, G, Snaebjornsson, P et al. (21 more authors) (2017) Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. Oncotarget, 8 (38). pp. 63140-63154. ISSN 1949-2553

Bosch, LJW, Trooskens, G, Snaebjornsson, P et al. (21 more authors) (2017) Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. Oncotarget, 8 (38). pp. 63140-63154. ISSN 1949-2553

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

C6003/A7367

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Bosch, LJW, Trooskens, G, Snaebjornsson, P et al. (21 more authors) (2017) Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. Oncotarget, 8 (38). pp. 63140-63154. ISSN 1949-2553

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

C6003/A7686

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Seymour, M orcid.org/0000-0002-2441-9629 (2019) Choosing the right strategy based on individualized treatment effect predictions: combination versus sequential chemotherapy in patients with metastatic colorectal cancer. Acta Oncologica, 58 (3). pp. 326-333. ISSN 0284-186X

Davidson, M, Chau, I, Cunningham, D et al. (5 more authors) (2017) Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer. World Journal of Gastrointestinal Oncology, 9 (8). pp. 333-340. ISSN 1948-5204

Salem, ME, Yin, J, Weinberg, BA et al. (18 more authors) (2018) Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. European Journal of Cancer, 103. pp. 205-213. ISSN 0959-8049

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

C6228/A12512

Giedl, J, Rogler, A, Wild, A et al. (9 more authors) (2016) TERT Core Promotor Mutations In Early-Onset Bladder Cancer. Journal of Cancer, 7 (8). pp. 915-920. ISSN 1837-9664

Pouessel, D, Neuzillet, Y, Mertens, LS et al. (35 more authors) (2016) Tumor Heterogeneity of Fibroblast Growth Factor Receptor 3 (FGFR3) Mutations in Invasive Bladder Cancer: Implications for Peri-Operative anti-FGFR3 Treatment. Annals of Oncology, 27 (7). pp. 1311-1316. ISSN 0923-7534

Turner, LD, Trinh, CH orcid.org/0000-0002-5087-5011, Hubball, RA et al. (5 more authors) (2022) From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. Journal of Medicinal Chemistry, 65 (2). pp. 1481-1504. ISSN 0022-2623

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

C6228/A5433

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

C6228/A5569

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

C63579/A26206

Santos, Á.D., Fili, N., Pearson, D.S. et al. (2 more authors) (2021) High throughput mechanobiology : force modulation of ensemble biochemical and cell-based assays. Biophysical Journal, 120 (4). pp. 631-641. ISSN 0006-3495

C64904/A27744

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

Barducci, L, Norton, J orcid.org/0000-0001-9981-5936, Sarker, S et al. (4 more authors) (2020) Fundamentals of the gut for capsule engineers. Progress in Biomedical Engineering, 2 (4). 042002. ISSN 2516-1091

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

Martin, JW orcid.org/0000-0002-4450-8127, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, JC orcid.org/0000-0001-9981-5936 et al. (4 more authors) (2020) Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation. Nature Machine Intelligence, 2 (10). pp. 595-606. ISSN 2522-5839

C7775/A14384

Kennedy, F orcid.org/0000-0002-4910-2505, Absolom, K orcid.org/0000-0002-5477-6643, Clayton, B et al. (6 more authors) (2020) Electronic Patient Reporting of Adverse Events and Quality of Life: A Prospective Feasibility Study in General Oncology. JCO Oncology Practice, 17 (3). e386-e396. ISSN 2688-1527

C7775/A7424

Santana, MJ, Haverman, L, Absolom, K orcid.org/0000-0002-5477-6643 et al. (4 more authors) (2015) Training clinicians in how to use patient-reported outcome measures in routine clinical practice. Quality of Life Research, 24 (7). pp. 1707-1718. ISSN 0962-9343

Taylor, RM, Fern, LA, Barber, J et al. (11 more authors) (2021) Specialist cancer services for teenagers and young adults in England: BRIGHTLIGHT research programme. Programme Grants for Applied Research, 9 (12). ISSN 2050-4322

Lindner, OC orcid.org/0000-0001-5442-8393, Velikova, G orcid.org/0000-0003-1899-5942 and Stark, DP orcid.org/0000-0002-6172-733X (2019) Digitally enabled patient-reported outcome measures in cancer care. The Lancet Oncology, 20 (1). e2-e2. ISSN 1470-2045

Lindner, OC orcid.org/0000-0001-5442-8393, Velikova, G orcid.org/0000-0003-1899-5942 and Stark, DP orcid.org/0000-0002-6172-733X (2019) Digitally enabled patient-reported outcome measures in cancer care. The Lancet Oncology, 20 (1). e2-e2. ISSN 1470-2045

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

C7845/A10066

Painter, D, Barrans, S, Lacy, S et al. (8 more authors) (2019) Cell‐of‐origin in diffuse large B‐cell lymphoma: findings from the UK's population‐based Haematological Malignancy Research Network. British Journal of Haematology, 185 (4). pp. 781-784. ISSN 0007-1048

Arumugakani, G, Stephenson, SJ, Newton, DJ orcid.org/0000-0002-0214-1486 et al. (5 more authors) (2017) Early emergence of CD19-negative human antibody secreting cells at the plasmablast to plasma cell transition. Journal of Immunology, 198 (12). pp. 4618-4628. ISSN 0022-1767

C7845/A17723

Shrimpton, J, Care, MA orcid.org/0000-0001-6584-5889, Carmichael, J et al. (7 more authors) (2020) TLR-mediated activation of Waldenström macroglobulinemia B cells reveals an uncoupling from plasma cell differentiation. Blood Advances, 4 (12). pp. 2821-2836. ISSN 2473-9529

Bigley, V, Maisuria, S, Cytlak, U et al. (20 more authors) (2018) Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation. Journal of Allergy and Clinical Immunology, 141 (6). pp. 2234-2248. ISSN 0091-6749

Mace, EM, Bigley, V, Gunesch, JT et al. (30 more authors) (2017) Biallelic mutations in IRF8 impair human NK cell maturation and function. Journal of Clinical Investigation, 127 (1). pp. 306-320. ISSN 0021-9738

Cucco, F, Barrans, S, Sha, C et al. (21 more authors) (2020) Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit. Leukemia, 34. pp. 1329-1341. ISSN 0887-6924

Davies, A, Cummin, TE, Barrans, S et al. (21 more authors) (2019) Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial. The Lancet Oncology, 20 (5). pp. 649-662. ISSN 1470-2045

Stephenson, S, Care, MA orcid.org/0000-0001-6584-5889, Fan, I et al. (4 more authors) (2019) Growth factor-like gene regulation is separable from survival and maturation in antibody secreting cells. Journal of Immunology, 202 (4). pp. 1287-1300. ISSN 0022-1767

Care, MA, Stephenson, SJ, Barnes, NA et al. (7 more authors) (2016) Network analysis identifies proinflammatory plasma cell polarization for secretion of ISG15 in human autoimmunity. Journal of Immunology, 197 (4). pp. 1447-1459. ISSN 0022-1767

Lupino, L, Perry, T, Margielewska, S et al. (18 more authors) (2019) Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma. Leukemia, 33. pp. 2884-2897. ISSN 0887-6924

Robinson, E, Care, M orcid.org/0000-0001-6584-5889, Walker, K orcid.org/0000-0002-6694-2979 et al. (3 more authors) (2022) A System for In Vitro Generation of Mature Murine Plasma Cells Uncovers Differential Blimp-1/Prdm1 Promoter Usage. Journal of Immunology, 208 (2). pp. 514-525. ISSN 0022-1767

Arumugakani, G, Stephenson, SJ, Newton, DJ orcid.org/0000-0002-0214-1486 et al. (5 more authors) (2017) Early emergence of CD19-negative human antibody secreting cells at the plasmablast to plasma cell transition. Journal of Immunology, 198 (12). pp. 4618-4628. ISSN 0022-1767

Sha, C, Barrans, S, Cucco, F et al. (20 more authors) (2019) Molecular high-grade B cell lymphoma: defining a poor risk group requiring different approaches to therapy. Journal of Clinical Oncology, 37 (3). pp. 202-213. ISSN 0732-183X

C7852/A19772

Randon, G, Yaeger, R, Hechtman, JF et al. (23 more authors) (2021) EGFR Amplification in Metastatic Colorectal Cancer. Journal of the National Cancer Institute (JNCI), 113 (11). pp. 1561-1569. ISSN 0027-8874

Seligmann, JF and Seymour, MT orcid.org/0000-0002-2441-9629 (2017) Editorial: Use of Gene Expression Profiles to Distinguish Molecular Subtypes in Colorectal Cancer: Progression Toward Primetime. JNCI: Journal of the National Cancer Institute, 109 (7). djx019. ISSN 0027-8874

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Battisti, NML, Wallington, M, Ring, A et al. (12 more authors) (2018) Is age a barrier to chemotherapy? Rates of treatment in older patients with breast, colon or lung cancer in England in 2014: A national registry study. In: Annals of Oncology. 43rd ESMO Congress (ESMO 2018), 19-23 Oct 2018, Munich, Germany. Oxford University Press .

Adams, RA, Fisher, DJ, Graham, J et al. (19 more authors) (2021) Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. Journal of Clinical Oncology. JCO.21.01436-JCO.21.01436. ISSN 0732-183X

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Westwood, AC, Hemmings, GJ, Bottomley, D et al. (7 more authors) (2018) Comparison of Mismatch Repair Protein Expression Between Biopsies and Resections in Advanced Colon Cancer from the Phase II Group of the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S26-S26.

C8175/A7672

Hornigold, N, Dunn, KR, Craven, RA et al. (22 more authors) (2020) Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion. British Journal of Cancer, 123 (1). pp. 137-147. ISSN 0007-0920

Hornigold, N, Dunn, KR, Craven, RA et al. (22 more authors) (2020) Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion. British Journal of Cancer, 123 (1). pp. 137-147. ISSN 0007-0920

C8216/A11963

Wong, K, Robles-Espinoza, CD, Rodriguez, D et al. (22 more authors) (2019) Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma. JAMA dermatology, 155 (5). pp. 604-609. ISSN 2168-6068

C8216/A6129

Hardie, CM, Elliott, F, Chan, M et al. (3 more authors) (2020) Environmental exposures such as smoking and low vitamin D are predictive of poor outcome in cutaneous melanoma rather than other deprivation measures. Journal of Investigative Dermatology, 140 (2). pp. 327-337. ISSN 0022-202X

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Poźniak, J, Nsengimana, J, Laye, JP et al. (15 more authors) (2019) Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma. Cancer Research, 79 (10). pp. 2684-2696. ISSN 0008-5472

C8216/A8777

Hardie, CM, Elliott, F, Chan, M et al. (3 more authors) (2020) Environmental exposures such as smoking and low vitamin D are predictive of poor outcome in cutaneous melanoma rather than other deprivation measures. Journal of Investigative Dermatology, 140 (2). pp. 327-337. ISSN 0022-202X

Muralidhar, S, Filia, A, Nsengimana, J et al. (11 more authors) (2019) Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity. Cancer Research, 79 (23). pp. 5986-5998. ISSN 0008-5472

C8525/A21082

Chen, X. orcid.org/0000-0001-6987-5540, Hughes, R., Mullin, N. et al. (4 more authors) (2021) Atomic force microscopy reveals the mechanical properties of breast cancer bone metastases. bioRxiv. (Submitted)

Chen, X. orcid.org/0000-0001-6987-5540, Hughes, R., Mullin, N. et al. (4 more authors) (2021) Atomic force microscopy reveals the mechanical properties of breast cancer bone metastases. Nanoscale, 13 (43). pp. 18237-18246. ISSN 2040-3364

Hughes, R., Chen, X. orcid.org/0000-0001-6987-5540, Hunter, K.D. orcid.org/0000-0002-7873-0877 et al. (3 more authors) (2019) Bone marrow osteoprogenitors are depleted whereas osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid. The FASEB Journal, 33 (11). pp. 12768-12779. ISSN 0892-6638

Chen, X. orcid.org/0000-0001-6987-5540, Hughes, R., Mullin, N. et al. (4 more authors) (2020) Mechanical heterogeneity in the bone microenvironment as characterised by atomic force microscopy. bioRxiv. (Submitted)

Allocca, G., Hughes, R., Wang, N. orcid.org/0000-0002-2663-7515 et al. (4 more authors) (2019) The bone metastasis niche in breast cancer– potential overlap with the haematopoietic stem cell niche in vivo. Journal of Bone Oncology, 17. 100244. ISSN 2212-1374

C9267/A25152

Feng, H, Gusev, A, Pasaniuc, B et al. (249 more authors) (2020) Transcriptome‐wide association study of breast cancer risk by estrogen‐receptor status. Genetic Epidemiology, 44 (5). pp. 442-468. ISSN 0741-0395

Yaacob, H., Walters, K. orcid.org/0000-0002-5718-5734 and Cox, A. orcid.org/0000-0002-5138-1099 (2019) Utilizing the information from GWAS data to inform priors in Bayesian fine-mapping association studies. In: Human Heredity. 47th European Mathematical Genetics Meeting (EMGM), 08-09 Apr 2019, Dublin, Ireland. Karger , p. 247.

Kapoor, PM, Lindström, S, Behrens, S et al. (147 more authors) (2020) Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium. International Journal of Epidemiology, 49 (1). pp. 216-232. ISSN 0300-5771

Shu, X, Wu, L, Khankari, NK et al. (203 more authors) (2019) Associations of obesity and circulating insulin and glucose with breast cancer risk : a Mendelian randomization analysis. International Journal of Epidemiology, 48 (3). pp. 795-806. ISSN 0300-5771

Kramer, I, Hooning, MJ, Mavaddat, N et al. (264 more authors) (2020) Breast cancer polygenic risk score and contralateral breast cancer risk. The American Journal of Human Genetics, 107 (5). pp. 837-848. ISSN 0002-9297

Baxter, JS, Johnson, N, Tomczyk, K et al. (180 more authors) (2021) Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element. The American Journal of Human Genetics, 108 (7). pp. 1190-1203. ISSN 0002-9297

Zhang, R, Shen, S, Wei, Y et al. (48 more authors) (2022) A large-scale genome-wide gene-gene interaction study of lung cancer susceptibility in Europeans with a trans-ethnic validation in Asians. Journal of Thoracic Oncology, 17 (8). pp. 974-990.

Robertson, J.F.R., Coleman, R.E. orcid.org/0000-0002-4275-1043, Cheung, K.-L. et al. (21 more authors) (2020) Proliferation and AKT activity biomarker analyses after capivasertib (AZD5363) treatment of patients with ER+ invasive breast cancer (STAKT). Clinical Cancer Research, 26 (7). pp. 1574-1585. ISSN 1078-0432

CA101A

Robertson, J.F.R., Coleman, R.E. orcid.org/0000-0002-4275-1043, Cheung, K.-L. et al. (21 more authors) (2020) Proliferation and AKT activity biomarker analyses after capivasertib (AZD5363) treatment of patients with ER+ invasive breast cancer (STAKT). Clinical Cancer Research, 26 (7). pp. 1574-1585. ISSN 1078-0432

CA115

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

CH160052

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

CRUK 04 05 BUDGET

Salem, ME, Yin, J, Weinberg, BA et al. (18 more authors) (2018) Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. European Journal of Cancer, 103. pp. 205-213. ISSN 0959-8049

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

CRUK 05 06 BUDGET

Seymour, M orcid.org/0000-0002-2441-9629 (2019) Choosing the right strategy based on individualized treatment effect predictions: combination versus sequential chemotherapy in patients with metastatic colorectal cancer. Acta Oncologica, 58 (3). pp. 326-333. ISSN 0284-186X

Davidson, M, Chau, I, Cunningham, D et al. (5 more authors) (2017) Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer. World Journal of Gastrointestinal Oncology, 9 (8). pp. 333-340. ISSN 1948-5204

Salem, ME, Yin, J, Weinberg, BA et al. (18 more authors) (2018) Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. European Journal of Cancer, 103. pp. 205-213. ISSN 0959-8049

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Ferraro, DA, Zalcberg, JR, Shi, Q et al. (3 more authors) (2018) Associations of incidence of common adverse events (AEs) and survival outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first line chemotherapy: Findings from 9,812 pts in the ARCAD database. In: Journal of Clinical Oncology. 2018 Gastrointestinal Cancers Symposium, 18-20 Jan 2018, San Francisco, CA, USA. American Society of Clinical Oncology .

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

CRUK-A18349

Brown, S.R., Hall, A., Buckley, H.L. et al. (9 more authors) (2019) Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial. BMC Cancer, 19 (1). 582. ISSN 1471-2407

DRF-2012-05-201

Downing, A orcid.org/0000-0002-0335-7801, Glaser, AW, Finan, PJ et al. (7 more authors) (2019) Functional Outcomes and Health-Related Quality of Life After Curative Treatment for Rectal Cancer: A Population-Level Study in England. International Journal of Radiation Oncology*Biology*Physics, 103 (5). pp. 1132-1142. ISSN 0360-3016

DRF-2016-09-084

Smith, AF orcid.org/0000-0001-7709-1869, Shinkins, B orcid.org/0000-0001-5350-1018, Hall, PS et al. (2 more authors) (2019) Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomes. Clinical Chemistry, 65 (11). pp. 1363-1374. ISSN 0009-9147

DRIKXHAAS

Speight, R, Schmidt, M, Liney, G et al. (6 more authors) (2019) A 2018 IPEM audit of M RI in external beam radiotherapy treatment planning in the UK. In: Radiotherapy and Oncology. ESTRO 38, 26-30 Apr 2019, Milan, Italy. Elsevier BV , S317-S318.

Brown, S, Van Herk, M, Chuter, R et al. (18 more authors) (2018) Advanced Radiotherapy Technologies Network in the UK (ART-NET) - focus on lung cancer. In: Lung Cancer. 16th Annual British Thoracic Oncology Group Conference 2018, 24-26 Jan 2018, Dublin, Ireland. Elsevier , S60-S60.

Morris, C, Gooding, MJ, Henry, A orcid.org/0000-0002-5379-6618 et al. (1 more author) (2017) EP-1739: The feasibility of atlas-based automatic segmentation of MRI for prostate radiotherapy planning. In: ESTRO 36, Vienna, Austria.

Johnstone, E, Wyatt, J, Henry, A orcid.org/0000-0002-5379-6618 et al. (8 more authors) (2018) EP-2136: Assessing the stability of MRI geometric distortions on multiple scanners. In: Radiotherapy and Oncology. ESTRO 37, 20-24 Apr 2018, Barcelona, Spain. Elsevier , S1177-S1177.

Speight, R, Dubec, M, Eccles, C et al. (7 more authors) (2021) IPEM Guidelines on the use of MRI for external beam radiotherapy treatment planning. In: ESTRO 2021, 28-31 Aug 2021, Madrid, Spain & Online.

Speight, R, Schmidt, MA, Liney, G et al. (6 more authors) (2019) IPEM Topical Report: A 2018 IPEM survey of MRI use for external beam radiotherapy treatment planning in the UK. Physics in Medicine and Biology, 64 (17). ARTN: 175021. ISSN 0031-9155

Speight, R, Tyyger, M, Schmidt, MA et al. (16 more authors) (2021) IPEM Topical Report: An international IPEM survey of MRI use for external beam radiotherapy treatment planning. Physics in Medicine & Biology. ISSN 0031-9155

Speight, R, Dubec, M, Eccles, CL et al. (7 more authors) (2021) IPEM topical report: guidance on the use of MRI for external beam radiotherapy treatment planning. Physics in Medicine & Biology. ISSN 0031-9155

Slevin, F, Beasley, M, Needham, A et al. (4 more authors) (2019) Image quality of cone beam CT used as image-guidance for pelvic Stereotactic Ablative Radiotherapy. In: Radiotherapy and Oncology. ESTRO 38, 26-30 Apr 2019, Milan, Italy. Elsevier BV , S303-S303.

Brown, S, Beasley, M, Aznar, MC et al. (9 more authors) (2021) The Impact of Intra-thoracic Anatomical Changes upon the Delivery of Lung Stereotactic Ablative Radiotherapy. Clinical Oncology, 33 (10). e413-e421. ISSN 0936-6555

Slevin, F, Beasley, M, Lilley, J et al. (3 more authors) (2019) Inter and intra-fraction bowel motion during abdomino-pelvic stereotactic ablative radiotherapy. In: Radiotherapy and Oncology. ESTRO 38, 26-30 Apr 2019, Milan, Italy. Elsevier BV , S1082-S1083.

Harrington, K, Hall, E, Hawkins, M et al. (11 more authors) (2017) Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET). Clinical Oncology, 29 (11). pp. 707-710. ISSN 0936-6555

Johnstone, E, Wyatt, JJ, Henry, AM orcid.org/0000-0002-5379-6618 et al. (6 more authors) (2018) Systematic Review of Synthetic Computed Tomography Generation Methodologies for Use in Magnetic Resonance Imaging–Only Radiation Therapy. International Journal of Radiation Oncology - Biology - Physics, 100 (1). pp. 199-217. ISSN 0360-3016

Brown, S, Beasley, M, McNair, H et al. (5 more authors) (2019) The UK lung SABR survey on behalf of the Advanced Radiotherapy Technologies Network. In: Radiotherapy and Oncology. ESTRO 38, 26-30 Apr 2019, Milan, Italy. Elsevier BV , S619-S619.

Beasley, M, Brown, S, McNair, H et al. (5 more authors) (2019) The advanced radiotherapy network (ART-NET) UK lung stereotactic ablative radiotherapy survey: national provision and a focus on image guidance. The British Journal of Radiology, 92 (1098). ARTN 20180988. ISSN 0007-1285

Slevin, F orcid.org/0000-0002-7176-904X, Beasley, M, Zhong, J et al. (5 more authors) (2021) A feasibility study of hyoscine butylbromide (buscopan) to improve image quality of cone beam computed tomography during abdominal/pelvic Stereotactic Ablative Radiotherapy. BJR open, 3 (1). 20210045. p. 20210045. ISSN 2513-9878

Brown, S, Beasley, M, Chuter, R et al. (5 more authors) (2019) The impact of intra-thoracic anatomical changes upon the delivery of lung stereotactic ablative radiotherapy. In: Lung Cancer. 17th Annual British Thoracic Oncology Group Conference 2019, 23-25 Jan 2019, Dublin, Ireland. Elsevier , S74-S75.

ECMC

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

EMSG1J3R

Lloyd, KE, Hall, LH, Ziegler, L et al. (5 more authors) (2022) Primary care physicians’ willingness t o prescribe aspirin for cancer preventive therapy: A randomised vignette study. In: 2022 ABM Annual Meeting, 06 Apr 2022.

EP/P023266/1

McVeigh, LE, Wijetunga, I, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2019) Development of orthotopic tumour models using ultrasound-guided intrahepatic injection. Scientific Reports, 9. 9904. ISSN 2045-2322

EP/P027938/1

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

EP/P51097X/1

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

EP/R045291/1

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

EP/S001069/1

Bourn, M, Batchelor, DVB orcid.org/0000-0001-6489-9578, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2020) Organ on chip models for the evaluation of microbubble based therapeutic delivery. In: Proceedings of Microfluidics, BioMEMS, and Medical Microsystems XVIII. Microfluidics, BioMEMS, and Medical Microsystems XVIII, 01-06 Feb 2020, San Francisco, California, USA. Society of Photo-optical Instrumentation Engineers . ISBN 9781510632332

EP/V047914/1

Barducci, L, Scaglioni, B, Martin, J et al. (2 more authors) (2022) Active Stabilization of Interventional Tasks Utilizing a Magnetically Manipulated Endoscope. Frontiers in Robotics and AI, 9. 854081. ISSN 2296-9144

ES/L011891/1

Wilkins, E, Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2020) Evidence from big data in obesity research: International case studies. International Journal of Obesity, 44 (5). pp. 1028-1040. ISSN 0307-0565

ES/N00941X/1

Wilkins, E, Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2020) Evidence from big data in obesity research: International case studies. International Journal of Obesity, 44 (5). pp. 1028-1040. ISSN 0307-0565

ES/S007164/1

Wilkins, E, Aravani, A orcid.org/0000-0002-3976-7888, Downing, A orcid.org/0000-0002-0335-7801 et al. (6 more authors) (2020) Evidence from big data in obesity research: International case studies. International Journal of Obesity, 44 (5). pp. 1028-1040. ISSN 0307-0565

Fund No IT01

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

HEALTH-F4-2010-241669

Perron, G, Jandaghi, P, Solanki, S et al. (15 more authors) (2018) A General Framework for Interrogation of mRNA Stability Programs Identifies RNA-Binding Proteins that Govern Cancer Transcriptomes. Cell Reports, 23 (6). pp. 1639-1650. ISSN 2211-1247

L004PhD

Taggart, D, Andreou, T, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (7 more authors) (2018) Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking. Proceedings of the National Academy of Sciences of the United States of America, 115 (7). E1540-E1549. ISSN 0027-8424

L339

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

L346

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

L354 PA

Westwood, AC, Bottomley, D, Hemmings, GJ et al. (11 more authors) (2018) Comparison of Mutational Status in the EGFR Pathway Across Four Different Platforms in the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S15-S15.

Westwood, AC, Hemmings, GJ, Bottomley, D et al. (7 more authors) (2018) Comparison of Mismatch Repair Protein Expression Between Biopsies and Resections in Advanced Colon Cancer from the Phase II Group of the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S26-S26.

L367

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

L372

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

L376PA

Hurst, CD orcid.org/0000-0001-7719-1325, Alder, O orcid.org/0000-0002-7975-9727, Platt, FM et al. (15 more authors) (2017) Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency. Cancer Cell, 32 (5). pp. 701-715. ISSN 1535-6108

Turner, LD, Trinh, CH orcid.org/0000-0002-5087-5011, Hubball, RA et al. (5 more authors) (2022) From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. Journal of Medicinal Chemistry, 65 (2). pp. 1481-1504. ISSN 0022-2623

Hornigold, N, Dunn, KR, Craven, RA et al. (22 more authors) (2020) Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion. British Journal of Cancer, 123 (1). pp. 137-147. ISSN 0007-0920

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

L386

Bosch, LJW, Trooskens, G, Snaebjornsson, P et al. (21 more authors) (2017) Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer. Oncotarget, 8 (38). pp. 63140-63154. ISSN 1949-2553

Hale, MD, Nankivell, M, Hutchins, GG et al. (11 more authors) (2016) Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma –results from the UK MRC OE02 trial. Oncotarget, 7 (47). pp. 77565-77575. ISSN 1949-2553

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

Westwood, AC, Bottomley, D, Hemmings, GJ et al. (11 more authors) (2018) Comparison of Mutational Status in the EGFR Pathway Across Four Different Platforms in the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S15-S15.

Turnbull, SJ, West, E, Scott, K et al. (3 more authors) (2018) Chemotherapy to reverse diminished immune responses (IRs) associated with a raised neutrophil lymphocyte ratio (NLR) in patients with advanced colorectal cancer (aCRC). In: Journal of Clinical Oncology. American Society of Clinical Oncology, 24 May 2018. American Society of Clinical Oncology .

Bach, SP, Gilbert, A orcid.org/0000-0002-9142-1227, Brock, K et al. (20 more authors) (2021) Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study. The Lancet Gastroenterology and Hepatology, 6 (2). pp. 92-105. ISSN 2468-1253

Murakami, K, West, N orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041 et al. (6 more authors) (2019) Central Pathological Review of the International Phase III FOxTROT Trial: Comparison with the Local Pathological Evaluation. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S39-S39.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041 et al. (6 more authors) (2019) The Effect of Pre-Operative FOLFOX Chemotherapy in Advanced Colon Cancer on Histopathological Features: Analysis of the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S38-S38.

West, NP orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041, Magill, L et al. (5 more authors) (2019) FOxTROT: An International Randomised Controlled Trial Evaluating Neoadjuvant Chemotherapy for Colon Cancer in 1,052 Patients. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S20-S20.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Westwood, AC et al. (10 more authors) (2019) The Relationship Between DNA Mismatch Repair and Response to FOLFOX-based Pre-operative Chemotherapy in the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S17-S17.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Ide, R et al. (7 more authors) (2019) The Relationship Between Tumour Immune Profile and Response to FOLFOX-Based Pre-Operative Chemotherapy in the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley-Blackwell , S37-S37.

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

Westwood, AC, Hemmings, GJ, Bottomley, D et al. (7 more authors) (2018) Comparison of Mismatch Repair Protein Expression Between Biopsies and Resections in Advanced Colon Cancer from the Phase II Group of the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S26-S26.

L394

Levick, BA orcid.org/0000-0002-6371-8744, Gilbert, AJ, Spencer, KL orcid.org/0000-0002-6846-4341 et al. (5 more authors) (2020) Time to Surgery Following Short-Course Radiotherapy in Rectal Cancer and its Impact on Postoperative Outcomes. A Population-Based Study Across the English National Health Service, 2009–2014. Clinical Oncology, 32. e46-e52. ISSN 0936-6555

Taylor, JC orcid.org/0000-0002-2518-5799, Swinson, D, Seligmann, JF et al. (8 more authors) (2021) Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: can a regional intervention promote national change? International Journal of Cancer, 148 (4). pp. 845-856. ISSN 0020-7136

Morris, EJA, Goldacre, R, Spata, E et al. (18 more authors) (2021) Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study. The Lancet Gastroenterology & Hepatology. ISSN 2468-1253

Fenton, HM orcid.org/0000-0001-7824-2614, Finan, PJ, Milton, R et al. (4 more authors) (2020) National variation in pulmonary metastasectomy for colorectal cancer. Colorectal Disease. ISSN 1462-8910

Brown, PJ, Rossington, H orcid.org/0000-0002-4570-2730, Taylor, J orcid.org/0000-0002-2518-5799 et al. (5 more authors) (2019) Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice. European Radiology, 29 (9). pp. 5121-5128. ISSN 0938-7994

Fenton, HM orcid.org/0000-0001-7824-2614, Taylor, JC orcid.org/0000-0002-2518-5799, Lodge, JPA et al. (4 more authors) (2019) Variation in the Use of Resection for Colorectal Cancer Liver Metastases. Annals of Surgery, 270 (5). pp. 892-898. ISSN 0003-4932

Burr, NE orcid.org/0000-0003-1988-2982, Derbyshire, E, Taylor, J orcid.org/0000-0002-2518-5799 et al. (6 more authors) (2019) Variation in post-colonoscopy colorectal cancer across colonoscopy providers in English National Health Service: population based cohort study. BMJ, 367. l6090. ISSN 1759-2151

Taylor, JC orcid.org/0000-0002-2518-5799, Iversen, LH, Burke, D orcid.org/0000-0002-4342-7464 et al. (7 more authors) (2021) Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease, 23 (12). pp. 3152-3161. ISSN 1462-8910

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

LPP034

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

LPP041

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

M14-0138:1

Okan, Y orcid.org/0000-0001-7963-1363, Stone, ER and Bruine de Bruin, W orcid.org/0000-0002-1601-789X (2018) Designing Graphs that Promote Both Risk Understanding and Behavior Change. Risk Analysis, 38 (5). pp. 929-946. ISSN 0272-4332

Okan, Y orcid.org/0000-0001-7963-1363, Stone, ER, Parillo, J et al. (2 more authors) (2020) Probability Size Matters: The Effect of Foreground‐Only versus Foreground+Background Graphs on Risk Aversion Diminishes with Larger Probabilities. Risk Analysis, 40 (4). pp. 771-788. ISSN 0272-4332

MAWE1415R61

Munir, T, Howard, D orcid.org/0000-0003-3333-9783, McParland, L et al. (10 more authors) (2018) Obinutuzumab as consolidation after chemo-immunotherapy is highly effective in achieving MRD clearance from bone marrow and peripheral blood-Initial results of UK NCRI Phase II/III GALACTIC trial. In: British Journal of Haematology. 58th Annual Scientific Meeting of the British Society for Haematology, 16-18 Apr 2018, Liverpool, UK. Wiley , p. 79.

MR/K012665/1

Wasson, CW, Morgan, EL, Muller, M orcid.org/0000-0002-2878-464X et al. (4 more authors) (2017) Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle. Oncotarget, 8 (61). pp. 103581-103600. ISSN 1949-2553

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

MR/L01629X/1

Sha, C, Barrans, S, Cucco, F et al. (20 more authors) (2019) Molecular high-grade B cell lymphoma: defining a poor risk group requiring different approaches to therapy. Journal of Clinical Oncology, 37 (3). pp. 202-213. ISSN 0732-183X

Robles-Espinoza, CD, Roberts, ND, Chen, S et al. (8 more authors) (2016) Germline MC1R status influences somatic mutation burden in melanoma. Nature Communications, 7. 12064.

McVeigh, LE, Wijetunga, I, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2019) Development of orthotopic tumour models using ultrasound-guided intrahepatic injection. Scientific Reports, 9. 9904. ISSN 2045-2322

MR/M016587/1

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

MR/M020606/1; MR/M020606/2

Santos, Á.D., Fili, N., Pearson, D.S. et al. (2 more authors) (2021) High throughput mechanobiology : force modulation of ensemble biochemical and cell-based assays. Biophysical Journal, 120 (4). pp. 631-641. ISSN 0006-3495

MR/N021339/1

Spencer, K orcid.org/0000-0002-6846-4341, Ellis, R, Birch, R orcid.org/0000-0003-1579-1397 et al. (6 more authors) (2017) Caution is required in the implementation of 90-day mortality indicators for radiotherapy in a curative setting: A retrospective population-based analysis of over 16,000 episodes. Radiotherapy and Oncology, 125 (1). pp. 140-146. ISSN 0167-8140

MR/N029976/1

Cocco, P, Ayaz-Shah, A orcid.org/0000-0001-6258-947X, Messenger, MP et al. (2 more authors) (2020) Target Product Profiles for medical tests: a systematic review of current methods. BMC Medicine, 8. 119. ISSN 1741-7015

MR/P026206/1

Hope, HC, Brownlie, RJ orcid.org/0000-0003-4897-1044, Fife, CM et al. (3 more authors) (2021) Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation. JCI Insight, 6 (9). ISSN 2379-3708

N/A

Brown, PJ, Zhong, J, Frood, R orcid.org/0000-0003-2681-9922 et al. (5 more authors) (2019) Prediction of outcome in anal squamous cell carcinoma using radiomic feature analysis of pre-treatment FDG PET-CT. European Journal of Nuclear Medicine and Molecular Imaging, 46 (13). pp. 2790-2799. ISSN 1619-7070

Gilbert, A, Drinkwater, K, McParland, L et al. (7 more authors) (2020) UK national cohort of anal cancer treated with intensity-modulated radiotherapy: One-year oncological and patient-reported outcomes. European Journal of Cancer, 128. pp. 7-16. ISSN 0959-8049

Ji, X, Mukherjee, S, Landi, MT et al. (108 more authors) (2020) Protein-altering germline mutations implicate novel genes related to lung cancer development. Nature Communications, 11 (1). 2220.

Levick, BA orcid.org/0000-0002-6371-8744, Gilbert, AJ, Spencer, KL orcid.org/0000-0002-6846-4341 et al. (5 more authors) (2020) Time to Surgery Following Short-Course Radiotherapy in Rectal Cancer and its Impact on Postoperative Outcomes. A Population-Based Study Across the English National Health Service, 2009–2014. Clinical Oncology, 32. e46-e52. ISSN 0936-6555

NAF\R2\180782

Simonin-Wilmer, I, Orozco-del-Pino, P, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (2 more authors) (2021) An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations. Frontiers in Genetics, 12. 703901. ISSN 1664-8021

Avitabile, M, Succoio, M, Testori, A et al. (25 more authors) (2020) Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Carcinogenesis, 41 (3). pp. 284-295. ISSN 0143-3334

NCRN CC

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Selby, P, Liu, L, Downing, A orcid.org/0000-0002-0335-7801 et al. (10 more authors) (2019) How can clinical research improve European health outcomes in cancer? Journal of Cancer Policy, 20. ARTN 100182. ISSN 2213-5383

Adams, R, Brown, E, Brown, L et al. (14 more authors) (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. Lancet Gastroenterology and Hepatology, 3 (3). pp. 162-171. ISSN 2468-1253

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NCRN-EORTC-CR-UK LIASION

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NIHR 129268

Lee, RW, Danson, S, Elliot, M et al. (8 more authors) (2022) Importance of clinical research for the UK's 10-year cancer plan. The Lancet Oncology. ISSN 1470-2045

NIHR Surgical MIC MF

Cocco, P, Ayaz-Shah, A orcid.org/0000-0001-6258-947X, Messenger, MP et al. (2 more authors) (2020) Target Product Profiles for medical tests: a systematic review of current methods. BMC Medicine, 8. 119. ISSN 1741-7015

Bradley, SH orcid.org/0000-0002-2038-2056, Abraham, S, Callister, MEJ et al. (5 more authors) (2019) Sensitivity of chest X-ray for detecting lung cancer in people presenting with symptoms: a systematic review. British Journal of General Practice, 69 (689). e827-e835. ISSN 0960-1643

Smith, AF orcid.org/0000-0001-7709-1869, Shinkins, B orcid.org/0000-0001-5350-1018, Hall, PS et al. (2 more authors) (2019) Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomes. Clinical Chemistry, 65 (11). pp. 1363-1374. ISSN 0009-9147

NO EXT REF GIVEN

Lindner, OC orcid.org/0000-0001-5442-8393, Velikova, G orcid.org/0000-0003-1899-5942 and Stark, DP orcid.org/0000-0002-6172-733X (2019) Digitally enabled patient-reported outcome measures in cancer care. The Lancet Oncology, 20 (1). e2-e2. ISSN 1470-2045

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

NON GIVEN

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

NONE GIVEN

Arumugakani, G, Stephenson, SJ, Newton, DJ orcid.org/0000-0002-0214-1486 et al. (5 more authors) (2017) Early emergence of CD19-negative human antibody secreting cells at the plasmablast to plasma cell transition. Journal of Immunology, 198 (12). pp. 4618-4628. ISSN 0022-1767

Brownhill, SC and Burchill, SA (2017) PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers – Focus on neuroblastoma. Practical Laboratory Medicine, 7. pp. 41-44. ISSN 2352-5517

NOT GIVEN

Sjoquist, KM, Renfro, LA, Simes, RJ et al. (31 more authors) (2017) Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. Journal of the National Cancer Institute, 10 (6). djx253. ISSN 0027-8874

Athauda, A, Nankivell, M, Langley, RE et al. (6 more authors) (2020) Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03). European Journal of Cancer, 137. pp. 45-56. ISSN 0959-8049

Hoorn, ST, Sommeijer, DW, Elliot, F et al. (12 more authors) (2021) Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone. British Journal of Cancer. ISSN 0007-0920

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Yin, J, Cohen, R, Jin, Z et al. (23 more authors) (2021) Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. Journal of the National Cancer Institute. ISSN 0027-8874

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Yin, J, Cohen, R, Jin, Z et al. (16 more authors) (2020) Prognostic and predictive impact of primary tumor sidedness in first-line trials for advanced colorectal cancer: An analysis of 7,828 patients in the ARCAD database. In: 2020 Gastrointestinal Cancers Symposium, 23-25 Jan 2020, San Francisco, California.

Burzykowski, T, Coart, E, Saad, ED et al. (24 more authors) (2019) Evaluation of Continuous Tumor-Size–Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Network Open, 2 (9). e1911750.

Seligmann, JF, Hatch, AJ, Richman, SD orcid.org/0000-0003-3993-5041 et al. (8 more authors) (2018) Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer. JAMA Oncology, 4 (4). pp. 564-568. ISSN 2374-2437

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

Lindner, OC orcid.org/0000-0001-5442-8393, Velikova, G orcid.org/0000-0003-1899-5942 and Stark, DP orcid.org/0000-0002-6172-733X (2019) Digitally enabled patient-reported outcome measures in cancer care. The Lancet Oncology, 20 (1). e2-e2. ISSN 1470-2045

Brown, LC, Graham, J, Fisher, D et al. (15 more authors) (2022) Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer. Clinical Trials, 19 (2). pp. 146-157. ISSN 1740-7745

No Ext Ref

Taylor, JC orcid.org/0000-0002-2518-5799, Iversen, LH, Burke, D orcid.org/0000-0002-4342-7464 et al. (7 more authors) (2021) Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease, 23 (12). pp. 3152-3161. ISSN 1462-8910

No Ext Ref Given

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Taggart, D, Andreou, T, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (7 more authors) (2018) Anti-PD-1/anti-CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8+ T cell trafficking. Proceedings of the National Academy of Sciences of the United States of America, 115 (7). E1540-E1549. ISSN 0027-8424

Taylor, RM, Fern, LA, Barber, J et al. (11 more authors) (2021) Specialist cancer services for teenagers and young adults in England: BRIGHTLIGHT research programme. Programme Grants for Applied Research, 9 (12). ISSN 2050-4322

Lindner, OC orcid.org/0000-0001-5442-8393, Velikova, G orcid.org/0000-0003-1899-5942 and Stark, DP orcid.org/0000-0002-6172-733X (2019) Digitally enabled patient-reported outcome measures in cancer care. The Lancet Oncology, 20 (1). e2-e2. ISSN 1470-2045

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

No Ref

Brownhill, SC and Burchill, SA (2017) PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers – Focus on neuroblastoma. Practical Laboratory Medicine, 7. pp. 41-44. ISSN 2352-5517

No ref given

Fernandez, S, Beasley, M, Lilley, J et al. (2 more authors) (2021) Establishing a Link Between Commonly Reported Toxicities and Tumour Location in Brain Tumour Patients Treated With Volumetric-modulated Arc Radiotherapy. Clinical Oncology, 33 (1). e97-e98. ISSN 0936-6555

Not Known

Samson, A orcid.org/0000-0002-3081-7850, Scott, KJ orcid.org/0000-0002-5790-9579, Taggart, D et al. (36 more authors) (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine, 10 (422). eaam7577. ISSN 1946-6234

Bradley, S orcid.org/0000-0002-2038-2056, Bhartia, BSK, Callister, MEJ et al. (7 more authors) (2021) Chest x-ray sensitivity and lung cancer outcomes: A retrospective observational study. British Journal of General Practice, 71 (712). e862-e868. ISSN 0960-1643

Renzi, C, Kaushal, A, Emery, J et al. (8 more authors) (2019) Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms. Nature Reviews Clinical Oncology, 16 (12). pp. 746-761. ISSN 1759-4774

Savage, R, Messenger, M orcid.org/0000-0002-4975-0158, Neal, RD et al. (12 more authors) (2022) Development and validation of multivariable machine learning algorithms to predict risk of cancer in symptomatic patients referred urgently from primary care: a diagnostic accuracy study. BMJ Open, 12 (4). e053590. ISSN 2044-6055

Walter, FM, Thompson, MJ, Wellwood, I et al. (12 more authors) (2019) Evaluating diagnostic strategies for early detection of cancer: the CanTest framework. BMC CANCER, 19. ARTN 586. ISSN 1471-2407

Calanzani, N, Druce, PE, Snudden, C et al. (10 more authors) (2021) Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Upper Gastrointestinal Cancers: A Systematic Review. Advances in Therapy, 38 (2). pp. 3032-3065. ISSN 0741-238X

di Martino, E, Smith, L, Bradley, SH orcid.org/0000-0002-2038-2056 et al. (6 more authors) (2022) Incidence trends for twelve cancers in younger adults-a rapid review. British Journal of Cancer, 126. pp. 1374-1386. ISSN 0007-0920

Neal, RD orcid.org/0000-0002-3544-2744, Sun, F, Emery, JD et al. (1 more author) (2019) Lung cancer. BMJ, 365. ARTN l1725. ISSN 0959-8138

Hatton, N, Bhartia, B, Aslam, R et al. (9 more authors) (2021) A Prospective Cohort Evaluation of the Sensitivity and Specificity of the Chest X-Ray for the Detection of Lung Cancer in Symptomatic Adults. In: Journal of Thoracic Oncology. 2021 World Conference on Lung Cancer Worldwide Virtual Event, 08-14 Sep 2021, Online. Elsevier , S1180-S1181.

Bradley, S orcid.org/0000-0002-2038-2056, Kennedy, MPT and Neal, RD orcid.org/0000-0002-3544-2744 (2018) Recognising Lung Cancer in Primary Care. Advances in Therapy. ISSN 1865-8652

Craig, Z orcid.org/0000-0001-9930-6648, Swain, J, Batman, E et al. (16 more authors) (2020) NET-02 trial protocol: a multicentre, randomised, parallel group, open-label, phase II, single-stage selection trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients with progressive poorly differentiated extrapulmonary neuroendocrine carcinoma (NEC). BMJ Open, 10 (2). e034527. ISSN 2044-6055

McNamara, MG, Swain, J, Craig, Z et al. (11 more authors) (2019) NET-02: A multi-center, randomised, phase II trial of liposomal irinotecan (nal-IRI) and 5-fluorouracil (5-FU)/folinic acid or docetaxel as second-line therapy in patients (pts) with progressive poorly differentiated extra-pulmonary neuroendocrine carcinoma (PD-EP-NEC). In: Journal of Clinical Oncology. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), 31 May - 04 Jun 2019, Chicago, IL, USA. American Society of Clinical Oncology .

Brownhill, SC and Burchill, SA (2017) PCR-based amplification of circulating RNAs as prognostic and predictive biomarkers – Focus on neuroblastoma. Practical Laboratory Medicine, 7. pp. 41-44. ISSN 2352-5517

Theophanous, S, Samuel, R, Lilley, J et al. (4 more authors) (2022) Prognostic factors for patients with anal cancer treated with conformal radiotherapy—a systematic review. BMC Cancer, 22 (1). 607. ISSN 1471-2407

Møller, DS, Lutz, CM, Khalil, AA et al. (8 more authors) (2022) Survival benefits for non-small cell lung cancer patients treated with adaptive radiotherapy. Radiotherapy and Oncology. ISSN 0167-8140

Adams, RA, Fisher, DJ, Graham, J et al. (19 more authors) (2021) Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial. Journal of Clinical Oncology. JCO.21.01436-JCO.21.01436. ISSN 0732-183X

Corrias, MV, Parodi, S, Tchirkov, A et al. (14 more authors) (2018) Event‐free survival of infants and toddlers enrolled in the HR‐NBL‐1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis. Pediatric Blood and Cancer, 65 (7). e27052. ISSN 1545-5009

Howard, DR, Hockaday, A, Brown, JM orcid.org/0000-0002-2719-7064 et al. (6 more authors) (2021) A platform trial in practice: adding a new experimental research arm to the ongoing confirmatory FLAIR trial in chronic lymphocytic leukaemia. Trials, 22 (1). 38. ISSN 1745-6215

Cocco, P, Ayaz-Shah, A orcid.org/0000-0001-6258-947X, Messenger, MP et al. (2 more authors) (2020) Target Product Profiles for medical tests: a systematic review of current methods. BMC Medicine, 8. 119. ISSN 1741-7015

Cocco, P, Ayaz-Shah, A orcid.org/0000-0001-6258-947X, Messenger, MP et al. (2 more authors) (2020) Target Product Profiles for medical tests: a systematic review of current methods. BMC Medicine, 8. 119. ISSN 1741-7015

Giancane, G, Diggle, CP, Legger, EG et al. (7 more authors) (2015) Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment. Journal of Rheumatology, 42 (11). 2211 - 2214. ISSN 0315-162X

Coulson, AB, Royle, K-L orcid.org/0000-0003-0225-1199, Pawlyn, C et al. (22 more authors) (2022) Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial. BMJ Open, 12 (6). e056147. ISSN 2044-6055

Bradley, SH orcid.org/0000-0002-2038-2056, Abraham, S, Callister, MEJ et al. (5 more authors) (2019) Sensitivity of chest X-ray for detecting lung cancer in people presenting with symptoms: a systematic review. British Journal of General Practice, 69 (689). e827-e835. ISSN 0960-1643

Bradley, SH orcid.org/0000-0002-2038-2056, Abraham, S, Callister, MEJ et al. (5 more authors) (2019) Sensitivity of chest X-ray for detecting lung cancer in people presenting with symptoms: a systematic review. British Journal of General Practice, 69 (689). e827-e835. ISSN 0960-1643

Smith, AF orcid.org/0000-0001-7709-1869, Shinkins, B orcid.org/0000-0001-5350-1018, Hall, PS et al. (2 more authors) (2019) Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomes. Clinical Chemistry, 65 (11). pp. 1363-1374. ISSN 0009-9147

Smith, AF orcid.org/0000-0001-7709-1869, Shinkins, B orcid.org/0000-0001-5350-1018, Hall, PS et al. (2 more authors) (2019) Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomes. Clinical Chemistry, 65 (11). pp. 1363-1374. ISSN 0009-9147

Sodergren, SC, Vassiliou, V, Dennis, K et al. (7 more authors) (2015) Systematic Review of the Quality of Life issues associated with Anal Cancer and its treatment with Radiochemotherapy. Supportive Care in Cancer, 23 (12). 3613 - 3623. ISSN 0941-4355

Liyanage, UE, Law, MH, Han, X et al. (8 more authors) (2019) Abstract 1592: Genome-wide meta-analysis of keratinocytic cancers identifies 26 novel risk loci. In: AACR Annual Meeting 2019, 29 Mar - 03 Apr 2019, Atlanta, GA, USA.

Dusingize, JC, Olsen, CM, An, J et al. (10 more authors) (2020) Body mass index and height and risk of cutaneous melanoma: Mendelian randomization analyses. International Journal of Epidemiology, 49 (4). pp. 1236-1245. ISSN 0300-5771

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Correction to: Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (5). p. 963. ISSN 0001-6322

Lindstrom, S, Kar, S, Wang, L et al. (25 more authors) (2020) Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions. In: AACR Annual Meeting 2020, 27 Apr - 24 Jun 2020, Philadelphia, PA, USA.

Feng, H, Majumdar, A, Pasaniuc, B et al. (20 more authors) (2020) Cross-cancer cross-tissue Transcriptome-wide Association Study (TWAS) of 11 cancers identifies 56 novel genes. In: AACR Annual Meeting 2020, 27 Apr 2020, Philadelphia, PA, USA.

Olsen, CM, Pandeya, N, Law, MH et al. (7 more authors) (2020) Does polygenic risk influence associations between sun exposure and melanoma?: a prospective cohort analysis. British Journal of Dermatology, 183 (2). pp. 303-310. ISSN 0007-0963

Cardinale, A, Cantalupo, S, Lasorsa, VA et al. (20 more authors) (2021) Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Human Molecular Genetics. ISSN 0964-6906

Chen, H, Majumdar, A, Wang, L et al. (75 more authors) (2021) Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances, 2 (3). 100041. ISSN 2666-2477

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (2). pp. 347-364. ISSN 0001-6322

Xu, M, Mehl, L, Zhang, T et al. (25 more authors) (2021) A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics, 108 (9). pp. 1611-1630. ISSN 0002-9297

Avitabile, M, Succoio, M, Testori, A et al. (25 more authors) (2020) Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Carcinogenesis, 41 (3). pp. 284-295. ISSN 0143-3334

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

Martin, JW orcid.org/0000-0002-4450-8127, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, JC orcid.org/0000-0001-9981-5936 et al. (4 more authors) (2020) Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation. Nature Machine Intelligence, 2 (10). pp. 595-606. ISSN 2522-5839

Stevens, C, Vrinten, C, Smith, SG orcid.org/0000-0003-1983-4470 et al. (2 more authors) (2019) Acceptability of receiving lifestyle advice at cervical, breast and bowel cancer screening. Preventive Medicine, 120. pp. 19-25. ISSN 0091-7435

Hall, LH, Thorneloe, R, Rodriguez-Lopez, R et al. (7 more authors) (2021) Delivering brief physical activity interventions in primary care: a systematic review of the prevalence, and factors associated with delivery, receipt, and patient receptivity. British Journal of General Practice. ISSN 0960-1643

Claire, S, Smith, SG, Quaife, SL et al. (3 more authors) (2019) Interest in lifestyle advice at lung cancer screening: Determinants and preferences. Lung Cancer, 128. pp. 1-5. ISSN 0169-5002

Stevens, C, Smith, SG orcid.org/0000-0003-1983-4470, Vrinten, C et al. (2 more authors) (2019) Lifestyle changes associated with participation in colorectal cancer screening: Prospective data from the English Longitudinal Study of Ageing. Journal of Medical Screening, 26 (2). pp. 84-91. ISSN 0969-1413

Jennings, VA, Scott, GB orcid.org/0000-0003-0021-9400, Rose, AMS et al. (13 more authors) (2019) Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition. Molecular Therapy, 27 (6). pp. 1139-1152. ISSN 1525-0016

Pallin, ND, Beeken, RJ orcid.org/0000-0001-8287-9351, Pritchard-Jones, K et al. (3 more authors) (2020) Therapeutic radiographers’ delivery of health behaviour change advice to those living with and beyond cancer: a qualitative study. BMJ Open, 10 (8). e039909. ISSN 2044-6055

Pallin, ND, Beeken, RJ orcid.org/0000-0001-8287-9351, Pritchard-Jones, K et al. (3 more authors) (2020) Therapeutic radiographers’ delivery of health behaviour change advice to those living with and beyond cancer: a qualitative study. BMJ Open, 10 (8). e039909. ISSN 2044-6055

Di Martino, E, Tomlinson, DC orcid.org/0000-0003-4134-7484, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

PB-PG-1207-15237

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

PCI-32765CLL3003 Ibrutin

Collett, L, Howard, DR orcid.org/0000-0003-3333-9783, Munir, T et al. (11 more authors) (2017) Assessment of ibrutinib plus rituximab in front-line CLL (FLAIR trial): study protocol for a phase III randomised controlled trial. Trials, 18. 387. ISSN 1745-6215

PHE

Morris, EJA, Finan, PJ, Spencer, K et al. (7 more authors) (2016) Wide Variation in the Use of Radiotherapy in the Management of Surgically Treated Rectal Cancer Across the English National Health Service. Clinical Oncology, 28 (8). pp. 522-531. ISSN 0936-6555

PP015

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

PPS WS56

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

PROJECT GRANT 12-0023

Filia, A, Droop, A, Harland, M et al. (10 more authors) (2019) High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material. Scientific Reports, 9 (1). ARTN: 8908. ISSN 2045-2322

RCS REF 08-0843 SUBCONTR

Seymour, MT orcid.org/0000-0002-2441-9629 and Morton, D (2019) FOxTROT: an international randomised controlled trial in 1052 patients (pts) evaluating neoadjuvant chemotherapy (NAC) for colon cancer. In: Journal of Clinical Oncology. ASCO 2019, 31 May - 04 Jun 2019, Chicago. American Society of Clinical Oncology (ASCO) , p. 3504.

Westwood, AC, Bottomley, D, Hemmings, GJ et al. (11 more authors) (2018) Comparison of Mutational Status in the EGFR Pathway Across Four Different Platforms in the Fluoropyrimidine Oxaliplatin and Targeted Receptor Pre-Operative Therapy (FOxTROT) Trial. In: Journal of Pathology. Maastricht Pathology 2018. 11th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 19-22 Jun 2018, Maastricht. Wiley , S15-S15.

Murakami, K, West, N orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041 et al. (6 more authors) (2019) Central Pathological Review of the International Phase III FOxTROT Trial: Comparison with the Local Pathological Evaluation. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S39-S39.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041 et al. (6 more authors) (2019) The Effect of Pre-Operative FOLFOX Chemotherapy in Advanced Colon Cancer on Histopathological Features: Analysis of the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S38-S38.

West, NP orcid.org/0000-0002-0346-6709, Richman, SD orcid.org/0000-0003-3993-5041, Magill, L et al. (5 more authors) (2019) FOxTROT: An International Randomised Controlled Trial Evaluating Neoadjuvant Chemotherapy for Colon Cancer in 1,052 Patients. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S20-S20.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Westwood, AC et al. (10 more authors) (2019) The Relationship Between DNA Mismatch Repair and Response to FOLFOX-based Pre-operative Chemotherapy in the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley , S17-S17.

Murakami, K, West, NP orcid.org/0000-0002-0346-6709, Ide, R et al. (7 more authors) (2019) The Relationship Between Tumour Immune Profile and Response to FOLFOX-Based Pre-Operative Chemotherapy in the International Phase III FOxTROT Trial. In: Journal of Pathology. Leeds Pathology 2019. 12th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 02-04 Jul 2019, Leeds. Wiley-Blackwell , S37-S37.

RFPB: PB-PG-0107-12048

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

RP-PG-0611-20008

Kennedy, F orcid.org/0000-0002-4910-2505, Absolom, K orcid.org/0000-0002-5477-6643, Clayton, B et al. (6 more authors) (2020) Electronic Patient Reporting of Adverse Events and Quality of Life: A Prospective Feasibility Study in General Oncology. JCO Oncology Practice, 17 (3). e386-e396. ISSN 2688-1527

RP-PG-1209-10013

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

RS 8441 Selimetry Trial

Brown, SR, Hall, A, Buckley, H orcid.org/0000-0002-9829-5817 et al. (9 more authors) (2019) Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial. BMC Cancer, 19 (1). ARTN: 582. ISSN 1471-2407

S501

O'Shea, SJ orcid.org/0000-0002-1588-6022, Davies, JR and Newton-Bishop, JA (2016) Vitamin D, Vitamin A, the primary melanoma transcriptome and survival. British Journal of Dermatology, 175 (S2). pp. 30-34. ISSN 0007-0963

SP2/CHOICES/2010

Bekker, HL orcid.org/0000-0003-1978-5795, Winterbottom, AE, Butow, P et al. (6 more authors) (2013) Do personal stories make patient decision aids more effective? A critical review of theory and evidence. BMC Medical Informatics and Decision Making, 13(Suppl2). S9. ISSN 1472-6947

Brown, EA, Bekker, HL orcid.org/0000-0003-1978-5795, Davison, SN et al. (2 more authors) (2016) Supportive Care: Communication Strategies to Improve Cultural Competence in Shared Decision Making. Clinical Journal of the American Society of Nephrology, 11 (10). pp. 1902-1908. ISSN 1555-9041

Winterbottom, AE, Gavaruzzi, T, Mooney, A et al. (8 more authors) (2016) Patient Acceptability of the Yorkshire Dialysis Decision Aid (YoDDA) Booklet: A Prospective Non-Randomized Comparison Study Across 6 Predialysis Services. Peritoneal Dialysis International, 36 (4). pp. 374-381. ISSN 0896-8608

Marley, S, Bekker, HL orcid.org/0000-0003-1978-5795 and Bewick, BM (2016) Responding to personalised social norms feedback from a web-based alcohol reduction intervention for students: Analysis of think-aloud verbal protocols. Psychology and Health, 31 (9). pp. 1007-1024. ISSN 0887-0446

SUPAC 004

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

TB2017SHEF

Kapoor, PM, Lindström, S, Behrens, S et al. (147 more authors) (2020) Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium. International Journal of Epidemiology, 49 (1). pp. 216-232. ISSN 0300-5771

Shu, X, Wu, L, Khankari, NK et al. (203 more authors) (2019) Associations of obesity and circulating insulin and glucose with breast cancer risk : a Mendelian randomization analysis. International Journal of Epidemiology, 48 (3). pp. 795-806. ISSN 0300-5771

TB2017SHEF; TB2O19BAR

Feng, H, Gusev, A, Pasaniuc, B et al. (249 more authors) (2020) Transcriptome‐wide association study of breast cancer risk by estrogen‐receptor status. Genetic Epidemiology, 44 (5). pp. 442-468. ISSN 0741-0395

TB2O19BAR

Kramer, I, Hooning, MJ, Mavaddat, N et al. (264 more authors) (2020) Breast cancer polygenic risk score and contralateral breast cancer risk. The American Journal of Human Genetics, 107 (5). pp. 837-848. ISSN 0002-9297

Baxter, JS, Johnson, N, Tomczyk, K et al. (180 more authors) (2021) Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element. The American Journal of Human Genetics, 108 (7). pp. 1190-1203. ISSN 0002-9297

TRYMS

Swain, J., Smith, I., Smith, A. et al. (3 more authors) (2015) TRYMS : the ethical and practical considerations of a double-blind placebo controlled randomised clinical trial. In: Trials. 3rd International Clinical Trials Methodology Conference, 16-17 Nov 2015, Glasgow, UK. BioMed Central .

Smith, I., Swain, J., Marshall, H. et al. (4 more authors) (2015) Testosterone replacement in young male cancer survivors (TRYMS) - pragmatic adaptation of trial design for a trial struggling with recruitment. Trials, 16 (S2). O79. ISSN 1745-6215

TYA CAN COHORT STY G569

Stark, D, Bowen, D, Dunwoodie, E et al. (5 more authors) (2015) Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups. European Journal of Cancer, 51 (17). pp. 2643-2654. ISSN 0959-8049

Taylor, RM, Fern, LA, Barber, JA et al. (10 more authors) (2020) Longitudinal cohort study of the impact of specialist cancer services for teenagers and young adults on quality of life: outcomes from the BRIGHTLIGHT study. BMJ Open, 10 (11). e038471. ISSN 2044-6055

Lindner, OC orcid.org/0000-0001-5442-8393, Boon, IS, Joffe, J et al. (1 more author) (2020) Evaluation of the “Shared Community Follow‐up” after a germ cell tumour—A novel initiative for remote cancer follow‐up enhanced by online patient‐reported outcome measures. European Journal of Cancer Care, 29 (5). e13264. ISSN 0961-5423

X120

Hall, P, Swinson, D, Lord, S et al. (23 more authors) (2019) Optimizing Chemotherapy for Frail and Elderly Patients with Advanced Gastroesophageal Cancer (aGOAC): the GO2 Phase III Trial. In: 2019 NCRI Cancer Conference of National Cancer Research Institute, 03-05 Nov 2019, Glasgow, Scotland, UK.

Hall, PS, Swinson, D, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (32 more authors) (2021) Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer: The GO2 Phase 3 Randomized Clinical Trial. JAMA oncology, 7 (6). pp. 869-877. ISSN 2374-2437

X160111

Coulson, AB, Royle, K-L orcid.org/0000-0003-0225-1199, Pawlyn, C et al. (22 more authors) (2022) Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial. BMJ Open, 12 (6). e056147. ISSN 2044-6055

c588/A19167

O'Shea, SJ orcid.org/0000-0002-1588-6022, Davies, JR and Newton-Bishop, JA (2016) Vitamin D, Vitamin A, the primary melanoma transcriptome and survival. British Journal of Dermatology, 175 (S2). pp. 30-34. ISSN 0007-0963

Váraljai, R, Wistuba-Hamprecht, K, Seremet, T et al. (18 more authors) (2019) Application of circulating cell-free tumor DNA profiles for therapeutic monitoring and outcome prediction in genetically heterogeneous metastatic melanoma. JCO Precision Oncology. ISSN 2473-4284

Burn, J, Sheth, H, Elliott, F et al. (20 more authors) (2020) Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial. The Lancet, 395 (10240). pp. 1855-1863. ISSN 0140-6736

Zhang, T, Choi, J, Dilshat, R et al. (14 more authors) (2021) Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms. American Journal of Human Genetics (AJHG), 108 (9). pp. 1631-1646. ISSN 0002-9297

Nsengimana, J and Bishop, DT orcid.org/0000-0002-8752-8785 (2017) Design Considerations for Genetic Linkage and Association Studies. In: Statistical Human Genetics: Methods and Protocols. Methods in Molecular Biology, 1666 . Humana Press , New York , pp. 257-281. ISBN 9781493972739

Kato, S, Weng, QY, Insco, ML et al. (20 more authors) (2020) Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis. Cancer Discovery, 10 (7). pp. 980-997. ISSN 2159-8274

Tian, Y, Kim, AE, Bien, SA et al. (74 more authors) (2022) Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk. Journal of the National Cancer Institute. ISSN 0027-8874

O'Shea, SJ, Mitra, A, Graham, JL et al. (4 more authors) (2016) Histopathology of melanocytic lesions in a family with an inherited BAP1 mutation. Journal of Cutaneous Pathology, 43 (3). pp. 287-289. ISSN 0303-6987

Pluta, J, Pyle, LC, Nead, KT et al. (54 more authors) (2021) Identification of 22 susceptibility loci associated with testicular germ cell tumors. Nature Communications, 12. 4487. ISSN 2041-1723

Adams, DJ, Bishop, DT orcid.org/0000-0002-8752-8785 and Robles-Espinoza, CD (2020) Melanoma predisposition—A limited role for germline BRCA1 and BRCA2 variants. Pigment Cell & Melanoma Research, 33 (1). pp. 6-7. ISSN 1755-1471

Liyanage, U, MacGregor, S, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (24 more authors) (2022) Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma. The Journal of investigative dermatology, 142 (8). pp. 1607-1616. ISSN 0022-202X

Lu, Y, Bishop, DT and et al (2016) New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications, 7. 10495. ISSN 2041-1723

Artomov, M, Stratigos, AJ, Kim, I et al. (21 more authors) (2017) Rare Variant, Gene-Based Association Study of Hereditary Melanoma Using Whole-Exome Sequencing. JNCI: Journal of the National Cancer Institute, 109 (12). djx083. ISSN 0027-8874

Simonin-Wilmer, I, Orozco-del-Pino, P, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (2 more authors) (2021) An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations. Frontiers in Genetics, 12. 703901. ISSN 1664-8021

Filia, A, Droop, A, Harland, M et al. (10 more authors) (2019) High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material. Scientific Reports, 9 (1). ARTN: 8908. ISSN 2045-2322

Litchfield, K, Loveday, C, Levy, M et al. (9 more authors) (2018) Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene. European Urology, 73 (6). pp. 828-831. ISSN 0302-2838

Wong, K, Robles-Espinoza, CD, Rodriguez, D et al. (22 more authors) (2019) Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma. JAMA dermatology, 155 (5). pp. 604-609. ISSN 2168-6068

Hardie, CM, Elliott, F, Chan, M et al. (3 more authors) (2020) Environmental exposures such as smoking and low vitamin D are predictive of poor outcome in cutaneous melanoma rather than other deprivation measures. Journal of Investigative Dermatology, 140 (2). pp. 327-337. ISSN 0022-202X

Thakur, R, Laye, JP, Lauss, M et al. (14 more authors) (2019) Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma. Clinical Cancer Research, 25 (24). pp. 7424-7435. ISSN 1078-0432

Poźniak, J, Nsengimana, J, Laye, JP et al. (15 more authors) (2019) Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma. Cancer Research, 79 (10). pp. 2684-2696. ISSN 0008-5472

Steinberg, J, Iles, MM orcid.org/0000-0002-2603-6509, Lee, JY et al. (11 more authors) (2022) Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts. British Journal of Dermatology, 186 (5). pp. 823-834. ISSN 0007-0963

Laskar, R, Ferreiro‐Iglesias, A, Bishop, DT et al. (11 more authors) (2020) Risk factors for melanoma by anatomical site: an evaluation of aetiological heterogeneity. British Journal of Dermatology. ISSN 0007-0963

Juraleviciute, M, Pozniak, J, Nsengimana, J et al. (11 more authors) (2020) MX 2 is a novel regulator of cell cycle in melanoma cells. Pigment Cell & Melanoma Research, 33 (3). pp. 446-457. ISSN 1755-1471

Muralidhar, S, Filia, A, Nsengimana, J et al. (11 more authors) (2019) Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity. Cancer Research, 79 (23). pp. 5986-5998. ISSN 0008-5472

Robles-Espinoza, CD, Roberts, ND, Chen, S et al. (8 more authors) (2016) Germline MC1R status influences somatic mutation burden in melanoma. Nature Communications, 7. 12064.

Bishop, DT, Iles, MM orcid.org/0000-0002-2603-6509, Newton-Bishop, JA et al. (16 more authors) (2018) Abstract 234: Understanding melanoma susceptibility through GWAS of risk phenotypes. In: Cancer Research. AACR Annual Meeting 2018, 14-18 Apr 2018, Chicago, Illinois. American Association for Cancer Research .

Cust, AE, Drummond, M, Kanetsky, PA et al. (18 more authors) (2018) Assessing the incremental contribution of common genomic variants to melanoma risk prediction in two population-based studies. Journal of Investigative Dermatology, 138 (12). pp. 2617-2624. ISSN 0022-202X

Mangantig, E, Iles, MM orcid.org/0000-0002-2603-6509, Newton-Bishop, JA et al. (2 more authors) (2017) Combining Genetic, Transcriptomic and Clinical Variables to Predict Melanoma-specific Survival. In: Genetic Epidemiology. The 2017 Annual Meeting of the International Genetic Epidemiology Society, 09-11 Sep 2017, Cambridge, UK. Wiley , p. 688.

Gu, F, Chen, T-H, Pfeiffer, RM et al. (27 more authors) (2018) Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Human Molecular Genetics, 27 (23). pp. 4145-4156. ISSN 0964-6906

Visconti, A, Duffy, DL, Liu, F et al. (19 more authors) (2018) Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. Nature Communications, 9 (1). 1684. p. 1684. ISSN 2041-1723

Choi, J, Zhang, T, Vu, A et al. (21 more authors) (2019) Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion. Working Paper. Cold Spring Harbor Laboratory (Submitted)

Law, MH, Aoude, LG, Duffy, DL et al. (19 more authors) (2020) Multiplex melanoma families are enriched for polygenic risk. Human Molecular Genetics. ISSN 0964-6906

Duffy, DL, Zhu, G, Li, X et al. (42 more authors) (2018) Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 9. 4774. ISSN 2041-1723

Liyanage, UE, Law, MH, Ong, JS et al. (7 more authors) (2018) Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis. International Journal of Cancer, 143 (3). pp. 508-514. ISSN 0020-7136

Duffy, DL, Zhu, G, Li, X et al. (42 more authors) (2019) Publisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature Communications, 10. 299. ISSN 2041-1723

Fang, J, Jia, J, Makowski, M et al. (38 more authors) (2018) Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 9. p. 16159.

Choi, J, Xu, M, Makowski, MM et al. (16 more authors) (2017) A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. Nature Genetics, 49 (9). pp. 1287-1413. ISSN 1061-4036

Harland, M, Petljak, M, Robles-Espinoza, CD et al. (13 more authors) (2016) Germline TERT promoter mutations are rare in familial melanoma. Familial Cancer, 15 (1). pp. 139-144. ISSN 1389-9600

Cust, AE, Drummond, M, Bishop, DT orcid.org/0000-0002-8752-8785 et al. (15 more authors) (2019) Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure. Journal of the European Academy of Dermatology and Venereology, 33 (10). pp. 1874-1885. ISSN 0926-9959

Vuong, K, Armstrong, BK, Drummond, M et al. (12 more authors) (2020) Development and external validation study of a melanoma risk prediction model incorporating clinically assessed naevi and solar lentigines. The British Journal of Dermatology, 182 (5). pp. 1262-1268. ISSN 0007-0963

Nsengimana, J, Laye, J, Filia, A et al. (15 more authors) (2018) β-catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas. Journal of Clinical Investigation, 128 (5). pp. 2048-2063. ISSN 0021-9738

Liyanage, UE, Law, MH, Han, X et al. (8 more authors) (2019) Abstract 1592: Genome-wide meta-analysis of keratinocytic cancers identifies 26 novel risk loci. In: AACR Annual Meeting 2019, 29 Mar - 03 Apr 2019, Atlanta, GA, USA.

Dusingize, JC, Olsen, CM, An, J et al. (10 more authors) (2020) Body mass index and height and risk of cutaneous melanoma: Mendelian randomization analyses. International Journal of Epidemiology, 49 (4). pp. 1236-1245. ISSN 0300-5771

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Correction to: Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (5). p. 963. ISSN 0001-6322

Lindstrom, S, Kar, S, Wang, L et al. (25 more authors) (2020) Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions. In: AACR Annual Meeting 2020, 27 Apr - 24 Jun 2020, Philadelphia, PA, USA.

Feng, H, Majumdar, A, Pasaniuc, B et al. (20 more authors) (2020) Cross-cancer cross-tissue Transcriptome-wide Association Study (TWAS) of 11 cancers identifies 56 novel genes. In: AACR Annual Meeting 2020, 27 Apr 2020, Philadelphia, PA, USA.

Olsen, CM, Pandeya, N, Law, MH et al. (7 more authors) (2020) Does polygenic risk influence associations between sun exposure and melanoma?: a prospective cohort analysis. British Journal of Dermatology, 183 (2). pp. 303-310. ISSN 0007-0963

Cardinale, A, Cantalupo, S, Lasorsa, VA et al. (20 more authors) (2021) Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Human Molecular Genetics. ISSN 0964-6906

Chen, H, Majumdar, A, Wang, L et al. (75 more authors) (2021) Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances, 2 (3). 100041. ISSN 2666-2477

Dube, U, Ibanez, L, Budde, JP et al. (9 more authors) (2020) Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathologica, 139 (2). pp. 347-364. ISSN 0001-6322

Xu, M, Mehl, L, Zhang, T et al. (25 more authors) (2021) A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics, 108 (9). pp. 1611-1630. ISSN 0002-9297

Avitabile, M, Succoio, M, Testori, A et al. (25 more authors) (2020) Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Carcinogenesis, 41 (3). pp. 284-295. ISSN 0143-3334

ep/k034537/2

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

m16-4

Burr, NE orcid.org/0000-0003-1988-2982, Derbyshire, E, Taylor, J orcid.org/0000-0002-2518-5799 et al. (6 more authors) (2019) Variation in post-colonoscopy colorectal cancer across colonoscopy providers in English National Health Service: population based cohort study. BMJ, 367. l6090. ISSN 1759-2151

n/a

Woll, P., Gaunt, P., Danson, S. et al. (8 more authors) (2022) Olaparib as maintenance treatment in patients with chemosensitive small cell lung cancer (STOMP) : a randomised, double-blind, placebo-controlled phase II trial. Lung Cancer, 171. pp. 26-33. ISSN 0169-5002

Zhang, R, Shen, S, Wei, Y et al. (48 more authors) (2022) A large-scale genome-wide gene-gene interaction study of lung cancer susceptibility in Europeans with a trans-ethnic validation in Asians. Journal of Thoracic Oncology, 17 (8). pp. 974-990.

wm150122

Barducci, L, Norton, J orcid.org/0000-0001-9981-5936, Sarker, S et al. (4 more authors) (2020) Fundamentals of the gut for capsule engineers. Progress in Biomedical Engineering, 2 (4). 042002. ISSN 2516-1091

Martin, J, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, J orcid.org/0000-0001-9981-5936 et al. (2 more authors) (2019) Toward Autonomous Robotic Colonoscopy: Motion Strategies for Magnetic Capsule Navigation. In: 2018 IEEE International Conference on Cyborg and Bionic Systems (CBS). CBS 2018, 25-27 Oct 2018, Shenzen, China. IEEE , pp. 240-244. ISBN 9781538673553

Mamunes, AP, Campisano, F, Martin, J et al. (4 more authors) (2021) Magnetic flexible endoscope for colonoscopy: an initial learning curve analysis. Endoscopy International Open, 09 (02). E171-E180. ISSN 2364-3722

Onaizah, O, Koszowska, Z, Winters, C et al. (5 more authors) (2021) Guidelines for Robotic Flexible Endoscopy at the Time of COVID-19. Frontiers in Robotics and AI, 8. 612852. ISSN 2296-9144

Martin, JW orcid.org/0000-0002-4450-8127, Scaglioni, B orcid.org/0000-0003-4891-8411, Norton, JC orcid.org/0000-0001-9981-5936 et al. (4 more authors) (2020) Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation. Nature Machine Intelligence, 2 (10). pp. 595-606. ISSN 2522-5839

This list was generated on Fri May 3 04:18:30 2024 BST.