Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial

Brown, S.R., Hall, A., Buckley, H.L. et al. (9 more authors) (2019) Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial. BMC Cancer, 19 (1). 582. ISSN 1471-2407

Abstract

Metadata

Authors/Creators:
  • Brown, S.R.
  • Hall, A.
  • Buckley, H.L.
  • Flanagan, L.
  • Gonzalez de Castro, D.
  • Farnell, K.
  • Moss, L.
  • Gregory, R.
  • Newbold, K.
  • Du, Y.
  • Flux, G.
  • Wadsley, J.
Copyright, Publisher and Additional Information: © The Author(s). 2019. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Iodine refractory differentiated thyroid cancer; MEK inhibitor; Selumetinib; Radioiodoine therapy; Phase II; Dosimetry
Dates:
  • Accepted: 28 March 2019
  • Published (online): 14 June 2019
  • Published: 14 June 2019
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
FunderGrant number
Cancer Research UKCRUK-A18349
Depositing User: Symplectic Sheffield
Date Deposited: 30 Nov 2020 11:41
Last Modified: 30 Nov 2020 11:41
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: https://doi.org/10.1186/s12885-019-5541-4
Related URLs:

Share / Export

Statistics