Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial

Brown, SR, Hall, A, Buckley, H orcid.org/0000-0002-9829-5817 et al. (9 more authors) (2019) Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial. BMC Cancer, 19 (1). ARTN: 582. ISSN 1471-2407

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Iodine refractory differentiated thyroid cancer; MEK inhibitor; Selumetinib; Radioiodoine therapy; Phase II; Dosimetry
Dates:
  • Accepted: 8 May 2019
  • Published (online): 14 June 2019
  • Published: 14 June 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Clinical Trials Research (LICTR) (Leeds)
Funding Information:
FunderGrant number
Cancer Research UKRS 8441 Selimetry Trial
Depositing User: Symplectic Publications
Date Deposited: 14 Jun 2019 09:19
Last Modified: 25 Jun 2023 21:52
Status: Published
Publisher: BioMed Central
Identification Number: https://doi.org/10.1186/s12885-019-5541-4

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