Items where authors include "Thomas, J.A."

Article

Glover, C., Fairbanks, S., Robertson, C.C. et al. (3 more authors) (2025) An optical ratiometric approach using enantiopure luminescent metal complexes indicates changes in the average quadruplex DNA content as primary cells undergo multiple divisions. Dalton Transactions. ISSN 1477-9226

Varney, A.M. orcid.org/0000-0002-5943-161X, Smitten, K.L., Southam, H.M. et al. (4 more authors) (2024) In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions. ACS Infectious Diseases, 10 (9). pp. 3346-3357. ISSN 2373-8227

Noakes, F.F., Smitten, K.L., Maple, L.E.C. et al. (7 more authors) (2024) Phenazine cations as anticancer theranostics. Journal of the American Chemical Society, 146 (18). pp. 12836-12849. ISSN 0002-7863

Aderinto, S.O., John, T. orcid.org/0000-0001-6059-5964, Onawole, A. et al. (2 more authors) (2024) Iridium(iii)-based minor groove binding complexes as DNA photocleavage agents. Dalton Transactions, 53 (17). pp. 7282-7291. ISSN 1477-9226

Saeed, H.K. orcid.org/0000-0002-5430-3942, Jarman, P.J., Sreedharan, S. et al. (6 more authors) (2023) From chemotherapy to phototherapy – changing the therapeutic action of a metallo-intercalating RuII-ReI luminescent system by switching its sub-cellular location. Chemistry – A European Journal, 29 (34). e202300617. ISSN 0947-6539

Yusoh, N.A., Tiley, P.R., James, S.D. et al. (7 more authors) (2023) Discovery of ruthenium(II) metallocompound and olaparib synergy for cancer combination therapy. Journal of Medicinal Chemistry, 66 (10). pp. 6922-6937. ISSN 0022-2623

Aderinto, S.O. orcid.org/0000-0003-4489-2162, Thomas, J.A. orcid.org/0000-0002-8662-7917 and Robertson, C.C. (2023) 2,2′:4,4′′:4′,4′′′-Quaterpyridine: synthesis, crystal-structure description, and Hirshfeld surface analysis. Acta Crystallographica Section E Crystallographic Communications, 79 (4). pp. 356-360. ISSN 2056-9890

Smitten, K., Southam, H.M., Fairbanks, S. et al. (3 more authors) (2023) Clearing an ESKAPE pathogen in a model organism; a polypyridyl ruthenium(II) complex theranostic that treats a resistant Acinetobacter baumannii infection in Galleria mellonella. Chemistry – A European Journal, 29 (11). e202203555. ISSN 0947-6539

Pramanik, S.K. orcid.org/0000-0002-0294-8829, Sreedharan, S. orcid.org/0000-0001-9523-0404, Tiwari, R. et al. (7 more authors) (2022) Nanoparticles for super-resolution microscopy: intracellular delivery and molecular targeting. Chemical Society Reviews, 51 (24). pp. 9882-9916. ISSN 0306-0012

Gill, M.R., Jarman, P.J., Hearnden, V. et al. (6 more authors) (2022) A ruthenium(II) polypyridyl complex disrupts actin cytoskeleton assembly and blocks cytokinesis. Angewandte Chemie International Edition, 61 (27). e202117449. ISSN 1433-7851

Zubi, A., Alnafisah, H.A., Turega, S. et al. (4 more authors) (2022) Being positive is not everything – experimental and computational studies on the selectivity of a self‐assembled, multiple redox‐state receptor that binds anions with up to picomolar affinities. Chemistry – A European Journal, 28 (5). e202102465. ISSN 0947-6539

Dröge, F., Noakes, F.F., Archer, S.A. et al. (11 more authors) (2021) A dinuclear osmium(II) complex near-infrared nanoscopy probe for nuclear DNA. Journal of the American Chemical Society, 143 (48). pp. 20442-20453. ISSN 0002-7863

Newton, M.D., Fairbanks, S.D., Thomas, J.A. orcid.org/0000-0002-8662-7917 et al. (1 more author) (2021) A minimal load-and-lock Ru II luminescent DNA probe. Angewandte Chemie International Edition, 60 (38). pp. 20952-20959. ISSN 1433-7851

Newton, M.D., Fairbanks, S.D., Thomas, J.A. orcid.org/0000-0002-8662-7917 et al. (1 more author) (2021) A minimal load‐and‐lock Ru II luminescent DNA probe. Angewandte Chemie (German Edition), 133 (38). pp. 21120-21127. ISSN 0044-8249

Fairbanks, S.D., Pamanik, S.K., Thomas, J.A. orcid.org/0000-0002-8662-7917 et al. (2 more authors) (2021) The management of mercury from dental amalgam in wastewater effluent. Environmental Technology Reviews, 10 (1). pp. 213-223. ISSN 2162-2515

Grayson, J.D., Baumgartner, M.P., Santos Souza, C.D. et al. (20 more authors) (2021) Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo–PrPC binding and downstream pathways. Chemical Science, 12 (10). pp. 3768-3785. ISSN 2041-6520

Varney, A.M., Smitten, K.L., Thomas, J.A. orcid.org/0000-0002-8662-7917 et al. (1 more author) (2021) Transcriptomic analysis of the activity and mechanism of action of a ruthenium(II)-based antimicrobial that induces minimal evolution of pathogen resistance. ACS Pharmacology & Translational Science, 4 (1). pp. 168-178. ISSN 2575-9108

Sreedharan, S., Tiwari, R., Tyde, D. et al. (4 more authors) (2021) Nanocarriers used as probes for super-resolution microscopy. Materials Chemistry Frontiers, 5 (3). pp. 1268-1282.

Gill, M.R., Walker, M.G., Able, S. et al. (8 more authors) (2020) An 111In-labelled bis-ruthenium(ii) dipyridophenazine theranostic complex: mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells. Chemical Science, 11 (33). pp. 8936-8944. ISSN 2041-6520

Smitten, K.L., Thick, E.J., Southam, H.M. et al. (3 more authors) (2020) Mononuclear ruthenium(ii) theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA. Chemical Science, 11 (33). pp. 8828-8838. ISSN 2041-6520

Smitten, K.L., Scattergood, P.A., Kiker, C. et al. (2 more authors) (2020) Triazole-based osmium(II) complexes displaying red/near-IR luminescence : antimicrobial activity and super-resolution imaging. Chemical Science, 11 (33). pp. 8928-8935. ISSN 2041-6520

Singh, H., Sreedharan, S., Oyarzabal, E. et al. (7 more authors) (2020) Mitochondriotropic lanthanide nanorods : implications for multimodal imaging. Chemical Communications, 56 (57). pp. 7945-7948. ISSN 1359-7345

Raza, A., Archer, S.A., Fairbanks, S.D. et al. (5 more authors) (2020) A dinuclear ruthenium(II) complex excited by near-infrared light through two-photon absorption induces phototoxicity deep within hypoxic regions of melanoma cancer spheroids. Journal of the American Chemical Society, 142 (10). pp. 4639-4647. ISSN 0002-7863

Saeed, H.K., Sreedharan, S. and Thomas, J.A. orcid.org/0000-0002-8662-7917 (2020) Photoactive metal complexes that bind DNA and other biomolecules as cell probes, therapeutics, and theranostics. Chemical Communications, 56 (10). pp. 1464-1480. ISSN 1359-7345

Saeed, H., Sreedharan, S., Jarman, P.J. et al. (11 more authors) (2020) Making the right link to theranostics : the photophysical and biological properties of dinuclear Ru^II-Re^I dppz complexes depend on their tether. Journal of the American Chemical Society, 142 (2). pp. 1101-1111. ISSN 0002-7863

Smitten, K.L., Fairbanks, S.D., Robertson, C.C. et al. (3 more authors) (2019) Ruthenium based antimicrobial theranostics – using nanoscopy to identify therapeutic targets and resistance mechanisms in staphylococcus aureus. Chemical Science. ISSN 2041-6520

Smitten, K.L., Southam, H.M., de la Serna, J.B. orcid.org/0000-0002-1396-3338 et al. (5 more authors) (2019) Using nanoscopy to probe the biological activity of antimicrobial leads that display potent activity against pathogenic, multidrug resistant, gram-negative bacteria. ACS Nano, 13 (5). pp. 5133-5146. ISSN 1936-0851

Archer, S., Raza, A., Dröge, F. et al. (9 more authors) (2019) A dinuclear ruthenium(II) phototherapeutic that targets duplex and quadruplex DNA. Chemical Science, 10 (12). pp. 3502-3513. ISSN 2041-6520

Fairbanks, S.D. orcid.org/0000-0002-5063-1367, Robertson, C.C., Keene, F.R. orcid.org/0000-0001-7759-0465 et al. (2 more authors) (2019) Structural investigation into the threading intercalation of a chiral dinuclear ruthenium(II) polypyridyl complex through a B-DNA oligonucleotide. Journal of the American Chemical Society, 141 (11). pp. 4644-4652. ISSN 0002-7863

Singh, H., Sreedharan, S., Tiwari, K. et al. (5 more authors) (2019) Two photon excitable graphene quantum dots for structured illumination microscopy and imaging application: lysosome specificity and tissue-dependent imaging. Chemical Communications, 55 (4). pp. 521-524. ISSN 1359-7345

Pramanik, S.K., Sreedharan, S., Singh, H. et al. (6 more authors) (2018) Mitochondria Targeting Non-isocyanate-based Polyurethane Nanocapsules for Enzyme-Triggered Drug Release. Bioconjugate Chemistry, 29 (11). pp. 3532-3543. ISSN 1043-1802

Singh, H., Sreedharan, S., Tiwari, R. et al. (5 more authors) (2018) A fluorescent chemodosimeter for organelle-specific imaging of nucleoside polyphosphate dynamics in living cells. Crystal Growth and Design, 18 (11). pp. 7199-7206. ISSN 1528-7483

Derrat, H.S. orcid.org/0000-0002-8662-7917, Robertson, C.C. orcid.org/0000-0002-1419-9618, Meijer, A.J.H.M. orcid.org/0000-0003-4803-3488 et al. (1 more author) (2018) Turning intercalators into groove binders: synthesis, photophysics and DNA binding properties of tetracationic mononuclear ruthenium(ii)-based chromophore-quencher complexes. Dalton Transactions, 47 (35). pp. 12300-12307. ISSN 1477-9226

Gill, M.R., Menon, J.U., Jarman, P.J. orcid.org/0000-0002-6932-341X et al. (6 more authors) (2018) In-111-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells. Nanoscale, 10 (22). pp. 10596-10608. ISSN 2040-3364

Hoskere, A.A., Sreedharan, S., Ali, F. et al. (3 more authors) (2018) Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging. Chemical Communications, 54 (30). pp. 3735-3738. ISSN 1359-7345

Sreedharan, S., Sinopoli, A., Jarman, P.J. orcid.org/0000-0002-6932-341X et al. (7 more authors) (2018) Mitochondria-localising DNA-binding biscyclometalated phenyltriazole iridium(III) dipyridophenazene complexes: syntheses and cellular imaging properties. Dalton Transactions, 47 (14). pp. 4931-4940. ISSN 1477-9226

Ali, F., Aute, S., Sreedharan, S. et al. (5 more authors) (2018) Tracking HOCl concentrations across cellular organelles in real time using a super resolution microscopy probe. Chemical Communications, 54 (15). pp. 1849-1852. ISSN 1359-7345

Gill, M.R., Jarman, P.J. orcid.org/0000-0002-6932-341X, Swagata, H. et al. (6 more authors) (2018) A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(II) metallo-intercalator. Chemical Science, 9 (4). pp. 841-849. ISSN 2041-6520

Ali, F., Sreedharan, S., Ashoka, A.H. et al. (4 more authors) (2017) A super resolution probe to monitor HNO levels in the endoplasmic reticulum of cells. Analytical Chemistry , 89 (22). pp. 12087-12093. ISSN 0003-2700

Sreedharan, S., Gill, M., Garcia, E. et al. (9 more authors) (2017) Multimodal super-resolution optical microscopy using a transition metal-based probe provides unprecedented capabilities for imaging both nucle-ar chromatin and mitochondria. Journal of the American Chemical Society, 139 (44). pp. 15907-15913. ISSN 0002-7863

Saeed, H., Jarman, P., Archer, S. et al. (7 more authors) (2017) Homo- and heteroleptic phototoxic dinuclear metallo-intercalators based on RuII(dppn) intercalating moieties: synthesis, optical and biological studies. Angewandte Chemie International Edition, 56 (41). pp. 12628-12633. ISSN 1433-7851

Rabelo, R., Valdo, A.K., Robertson, C. et al. (7 more authors) (2017) Synthesis, crystal structure and magnetic properties of [Co(bpcam) 2 ]ClO 4 ·dmso·H 2 O, [Co(bpcam) 2 ] 2 [Co(NCS) 4 ]·dmso·H 2 O and [Ni(bpcam) 2 ]·H 2 O [Hbpcam = bis(2-pyrimidylcarbonyl)amide]. New Journal of Chemistry , 41 (14). pp. 6911-6921. ISSN 1144-0546

Thomas, J.A. orcid.org/0000-0002-8662-7917, Walker, M., Ramu, V. et al. (2 more authors) (2017) A ratiometric sensor for DNA based on a dual emission Ru(dppz) light-switch complex. Dalton Transactions, 46 (18). ISSN 1477-9226

Saeed, H.K., Saeed, I.Q., Buurma, N.J. et al. (1 more author) (2017) Inside Cover: The Structure of Linkers Affects the DNA Binding Properties of Tethered Dinuclear Ruthenium(II) Metallo-Intercalators (Chem. Eur. J. 23/2017). Chemistry - A European Journal, 23 (23). p. 5389. ISSN 0947-6539

Saaed, H.K., Saeed, I.Q., Buurma, N. et al. (1 more author) (2017) The structure of linkers affects the DNA binding properties of tethered dinuclear ruthenium (II) metallo-intercalator. Chemistry - A European Journal, 23 (23). pp. 5467-5477. ISSN 0947-6539

Ramu, V., Aute, S., Taye, N. et al. (7 more authors) (2017) Photo-Induced Cytotoxicity and Anti-Metastatic Activity of Ruthenium(II)-Polypyridyl Complexes Functionalized with Tyrosine or Tryptophan. Dalton Transactions, 46. pp. 6634-6644. ISSN 1477-9226

Walker, M.G., Jarman, P.J., Gill, M.R. et al. (9 more authors) (2016) A self-Assembled Metallomacrocycle Singlet Oxygen Sensitizer for Photodynamic Therapy. Chemistry - A European Journal, 22 (17). pp. 5996-6000. ISSN 0947-6539

Song, L., Guo, Y., Roebuck, D. et al. (10 more authors) (2015) Terminal PEGylated DNA-Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents. ACS Applied Materials and Interfaces, 7 (33). pp. 18707-18716. ISSN 1944-8244

Thomas, J.A. (2015) Optical imaging probes for biomolecules: an introductory perspective. Chemical Society Reviews, 44 (14). pp. 4494-4500. ISSN 0306-0012

Ramu, V., Gill, M.R., Jarman, P.J. et al. (4 more authors) (2015) A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase by up-regulating p27^KIP1. Chemistry - A European Journal, 21 (25). 9185 - 9197. ISSN 0947-6539

Zubi, A., Wragg, A., Turega, S. et al. (4 more authors) (2015) Correction: Modulating the electron-transfer properties of a mixed-valence system through host–guest chemistry. Chemical Science, 6 (7). pp. 4373-4374. ISSN 2041-6520

Ramu, V., Gill, M.R., Jarman, P.J. et al. (4 more authors) (2015) A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase by up-regulating p27KIP1. Chemistry - A European Journal, 21 (25). pp. 9185-9197. ISSN 0947-6539

Stimpson, S., Jenkinson, D.R. orcid.org/0000-0002-2237-4578, Sadler, A. et al. (4 more authors) (2015) Tuning the excited state of water-soluble IrIII-based DNA intercalators that are isostructural with [RuII(NN)2(dppz)] light-switch complexes. Angewandte Chemie International Edition, 54 (10). pp. 3000-3003. ISSN 1433-7851

Zubi, A., Wragg, A., Turega, S. et al. (4 more authors) (2015) Modulating the electron-transfer properties of a mixed-valence system through host-guest chemistry. Chemical Science, 6 (2). pp. 1334-1340. ISSN 2041-6520

Baggaley, E., Gill, M.R., Green, N.H. et al. (7 more authors) (2014) Dinuclear Ruthenium( II) Complexes as Two- Photon, Time- Resolved Emission Microscopy Probes for Cellular DNA. Angewandte Chemie International Edition, 53 (13). 3367 - 3371. ISSN 1433-7851

Baggaley, E., Gill, M.R., Green, N.H. orcid.org/0000-0001-5413-0642 et al. (7 more authors) (2014) Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA. Angewandte Chemie, 126 (13). pp. 3435-3439. ISSN 0044-8249

Gill, M., Cecchin, D., Walker, M.G. et al. (4 more authors) (2013) Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(II) polypyridyl complex. Chemical Science , 4. pp. 4512-4519. ISSN 2041-6520

Thomas, J.A. orcid.org/0000-0002-8662-7917 (2013) Tuning electronic interactions in mixed valence ruthenium systems incorporating thiacrown ligands. Coordination Chemistry Reviews, 257 (9-10). pp. 1555-1563. ISSN 0010-8545