Items where authors include "Radford, SE"

Article

Haysom, SF, Machin, J, Whitehouse, JM et al. (9 more authors) (2023) Darobactin B Stabilises a Lateral‐Closed Conformation of the BAM Complex in E. coli Cells. Angewandte Chemie International Edition, 62 (34). ISSN 1433-7851

Radford, SE orcid.org/0000-0002-3079-8039 and Summers, MF (2023) Changing Shape of Molecules. Journal of Molecular Biology, 435 (11). 168092. ISSN 0022-2836

Leistner, C, Wilkinson, M, Burgess, A et al. (7 more authors) (2023) The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain. Nature Communications, 14. 2833. ISSN 2041-1723

Marcuccio, F orcid.org/0000-0003-4816-2896, Soulias, D orcid.org/0000-0003-4700-6744, Chau, CCC orcid.org/0000-0002-3134-6798 et al. (4 more authors) (2023) Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer–Electrolyte Nanopore. ACS Nanoscience Au, 3 (2). pp. 172-181. ISSN 2694-2496

Wilkinson, M orcid.org/0000-0001-5490-613X, Gallardo, RU, Martinez, RM et al. (5 more authors) (2023) Disease-relevant β2-microglobulin variants share a common amyloid fold. Nature Communications, 14. 1190. ISSN 2041-1723

Byrd, EJ orcid.org/0000-0002-9876-1400, Wilkinson, M orcid.org/0000-0001-5490-613X, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2023) Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry, 34 (3). pp. 493-504. ISSN 1044-0305

Chau, C orcid.org/0000-0002-3134-6798, Marcuccio, F orcid.org/0000-0003-4816-2896, Soulias, D orcid.org/0000-0003-4700-6744 et al. (5 more authors) (2022) Probing RNA Conformations Using a Polymer–Electrolyte Solid-State Nanopore. ACS Nano, 16 (12). pp. 20075-20085. ISSN 1936-0851

Maya-Martinez, R, Xu, Y, Guthertz, N et al. (5 more authors) (2022) Dimers of D76N-β₂-microglobulin display potent antiamyloid aggregation activity. Journal of Biological Chemistry, 298 (12). 102659. ISSN 0021-9258

Ruff, KM, Choi, YH, Cox, D et al. (6 more authors) (2022) Sequence grammar underlying the unfolding and phase separation of globular proteins. Molecular Cell, 82 (17). 3193-3208.e8. ISSN 1097-2765

Ulamec, SM, Maya-Martinez, R, Byrd, EJ orcid.org/0000-0002-9876-1400 et al. (9 more authors) (2022) Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature Communications, 13. 4986. ISSN 2041-1723

Wu, K, Minshull, TC, Radford, SE orcid.org/0000-0002-3079-8039 et al. (2 more authors) (2022) Trigger factor both holds and folds its client proteins. Nature Communications, 13. 4126. ISSN 2041-1723

Schiffrin, B, Machin, JM, Karamanos, TK orcid.org/0000-0003-2297-540X et al. (4 more authors) (2022) Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding. Communications Biology, 5. 560. ISSN 2399-3642

Mclure, RJ, Radford, SE orcid.org/0000-0002-3079-8039 and Brockwell, DJ orcid.org/0000-0002-0802-5937 (2022) High-throughput directed evolution: a golden era for protein science. Trends in Chemistry, 4 (5). pp. 378-391. ISSN 2589-5974

Karamanos, TK orcid.org/0000-0003-2297-540X, Kalverda, AP and Radford, SE orcid.org/0000-0002-3079-8039 (2022) Generating Ensembles of Dynamic Misfolding Proteins. Frontiers in Neuroscience, 16. 881534. ISSN 1662-453X

Xu, Y, Maya-Martinez, R, Guthertz, N et al. (6 more authors) (2022) Tuning the rate of aggregation of hIAPP into amyloid using smallmolecule modulators of assembly. Nature Communications, 13. 1040. ISSN 2041-1723

Good, SG, Dewison, KM, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2021) Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans. International Journal of Molecular Sciences, 22 (19). 10752. ISSN 1661-6596

Cornwell, O, Ault, JR orcid.org/0000-0002-5131-438X, Bond, NJ et al. (2 more authors) (2021) An investigation of D76N β₂-microglobulin using protein footprinting and structural mass spectrometry. Journal of the American Society for Mass Spectrometry, 32 (7). pp. 1583-1592. ISSN 1044-0305

White, P, Haysom, SF, Iadanza, MG et al. (12 more authors) (2021) The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nature Communications, 12. 4174. ISSN 2041-1723

Nahass, GR, Sun, Y, Xu, Y et al. (12 more authors) (2021) Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium. Journal of Molecular Biology, 433 (8). 166878. ISSN 0022-2836

Bunce, SJ, Wang, Y, Radford, SE orcid.org/0000-0002-3079-8039 et al. (2 more authors) (2021) Structural insights into peptide self-assembly using photo-induced crosslinking experiments and discontinuous molecular dynamics. AIChE Journal, 67 (3). e17101. ISSN 0001-1541

Vorobieva, AA, White, P orcid.org/0000-0001-7536-4552, Liang, B et al. (16 more authors) (2021) De novo design of transmembrane β-barrels. Science, 371 (6531). eabc8182. ISSN 0036-8075

Milardi, D, Gazit, E, Radford, SE orcid.org/0000-0002-3079-8039 et al. (7 more authors) (2021) Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes. Chemical Reviews. ISSN 0009-2665

Cawood, EE, Karamanos, TK orcid.org/0000-0003-2297-540X, Wilson, AJ orcid.org/0000-0001-9852-6366 et al. (1 more author) (2021) Visualizing and trapping transient oligomers in amyloid assembly pathways. Biophysical Chemistry, 268. 106505. ISSN 0301-4622

Iadanza, MG, Schiffrin, B, White, P orcid.org/0000-0001-7536-4552 et al. (9 more authors) (2020) Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs. Communications Biology, 3. 766. ISSN 2399-3642

Cawood, E, Guthertz, N, Ebo, JS orcid.org/0000-0002-5684-4355 et al. (3 more authors) (2020) Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules. Journal of the American Chemical Society, 142 (49). pp. 20845-20854. ISSN 0002-7863

Ulamec, SM, Brockwell, DJ orcid.org/0000-0002-0802-5937 and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins. Frontiers in Neuroscience, 14 (611285). ISSN 1662-4548

Brown, MR, Radford, SE orcid.org/0000-0002-3079-8039 and Hewitt, E orcid.org/0000-0002-6238-6303 (2020) Modulation of β-amyloid fibril formation in Alzheimer’s disease by microglia and infection. Frontiers in Molecular Neuroscience, 13. 609073. ISSN 1662-5099

Gallardo, R orcid.org/0000-0003-1584-3564, Iadanza, MG, Xu, Y et al. (4 more authors) (2020) Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nature Structural & Molecular Biology, 27 (11). pp. 1048-1056. ISSN 1545-9993

Lauwers, E, Lalli, G, Brandner, S et al. (34 more authors) (2020) Potential human transmission of amyloid β pathology: surveillance and risks. Lancet Neurology, 19 (10). pp. 872-878. ISSN 1474-4422

Rodríguez-Alonso, R, Létoquart, J, Nguyen, VS et al. (7 more authors) (2020) Structural insight into the formation of lipoprotein-β-barrel complexes. Nature Chemical Biology, 16. pp. 1019-1025. ISSN 1552-4450

Schiffrin, B, Radford, SE orcid.org/0000-0002-3079-8039, Brockwell, DJ orcid.org/0000-0002-0802-5937 et al. (1 more author) (2020) PyXlinkViewer: A flexible tool for visualization of protein chemical crosslinking data within the PyMOL molecular graphics system. Protein Science, 29 (8). pp. 1851-1857. ISSN 0961-8368

Smith, HI, Guthertz, N, Cawood, EE et al. (3 more authors) (2020) The role of the IT-state in D76N β2-microglobulin amyloid assembly: a crucial intermediate or an innocuous bystander? Journal of Biological Chemistry. jbc.RA120.014901. ISSN 0021-9258

Chau, CC orcid.org/0000-0002-3134-6798, Radford, SE orcid.org/0000-0002-3079-8039, Hewitt, EW orcid.org/0000-0002-6238-6303 et al. (1 more author) (2020) Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore. Nano Letters, 20 (7). pp. 5553-5561. ISSN 1530-6984

Horne, JE, Brockwell, DJ orcid.org/0000-0002-0802-5937 and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Role of the lipid bilayer in outer membrane protein folding in Gram negative bacteria. Journal of Biological Chemistry. jbc.REV120.011473. ISSN 0021-9258

Ulamec, SM and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Spot the Difference: Function versus Toxicity in Amyloid Fibrils. Trends in Biochemical Sciences. ISSN 0968-0004

Calabrese, AN, Schiffrin, B, Watson, M et al. (11 more authors) (2020) Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients. Nature Communications, 11. 2155. ISSN 2041-1723

Willis, LF orcid.org/0000-0001-6616-3716, Kumar, A, Jain, T et al. (6 more authors) (2020) The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies. Engineering Reports, 2 (5). e12147. ISSN 2577-8196

Ebo, JS orcid.org/0000-0002-5684-4355, Saunders, JC, Devine, PWA et al. (12 more authors) (2020) An in vivo platform to select and evolve aggregation-resistant proteins. Nature Communications, 11. 1816. ISSN 2041-1723

Doherty, CPA, Ulamec, SM, Maya-Martinez, R et al. (6 more authors) (2020) A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function. Nature Structural & Molecular Biology, 27. pp. 249-259. ISSN 1545-9993

Gallardo, R orcid.org/0000-0003-1584-3564, Ranson, NA orcid.org/0000-0002-3640-5275 and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Amyloid Structures: Much More Than Just A Cross-β Fold. Current Opinion in Structural Biology, 60. pp. 7-16. ISSN 0959-440X

Ebo, JS, Guthertz, N, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2020) Using Protein Engineering to Understand and Modulate Aggregation. Current Opinion in Structural Biology, 60. pp. 157-166. ISSN 0959-440X

Hoop, CL, Zhu, J, Bhattacharya, S et al. (3 more authors) (2020) Collagen I weakly interacts with the β-sheets of β2-microglobulin and enhances conformational exchange to induce amyloid formation. Journal of the American Chemical Society, 142 (3). pp. 1321-1331. ISSN 0002-7863

Baum, J, Chiti, F, De Simone, A et al. (9 more authors) (2019) Homage to Chris Dobson. Frontiers in Molecular Biosciences, 6. 137. ISSN 2296-889X

Cornwell, O, Bond, NJ, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2019) Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS. Analytical Chemistry, 91 (23). pp. 15163-15170. ISSN 0003-2700

Karamanos, TK, Jackson, MP, Calabrese, AN et al. (6 more authors) (2019) Structural mapping of oligomeric intermediates in an amyloid assembly pathway. eLife, 8. e46574. ISSN 2050-084X

Benseny-Cases, N, Karamanos, TK, Hoop, CL et al. (2 more authors) (2019) Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation. The Journal of biological chemistry, 294. pp. 9392-9401. ISSN 0021-9258

Bunce, SJ, Wang, Y, Stewart, KL et al. (4 more authors) (2019) Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β₄₀ (Aβ₄₀) by the peptide fragment Aβ₁₆-₂₂. Science Advances, 5 (6). eaav8216. ISSN 2375-2548

Shen, K, Gamerdinger, M, Chan, R et al. (12 more authors) (2019) Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. Molecular Cell, 74 (4). 729-741.e7. ISSN 1097-2765

Humes, JR orcid.org/0000-0002-1407-7880, Schiffrin, B, Calabrese, AN et al. (4 more authors) (2019) The Role of SurA PPIase Domains in Preventing Aggregation of the Outer Membrane Proteins tOmpA and OmpT. Journal of Molecular Biology, 431 (6). pp. 1267-1283. ISSN 0022-2836

Walko, M, Hewitt, E orcid.org/0000-0002-6238-6303, Radford, SE orcid.org/0000-0001-9668-6366 et al. (1 more author) (2019) Design and Synthesis of Cysteine-Specific Labels for Photo-Crosslinking Studies. RSC Advances, 9 (14). pp. 7610-7614. ISSN 2046-2069

Wang, Y, Bunce, SJ, Radford, SE orcid.org/0000-0001-9668-6366 et al. (3 more authors) (2019) Thermodynamic phase diagram of amyloid-β (16-22) peptide. Proceedings of the National Academy of Sciences of the United States of America, 116 (6). pp. 2091-2096. ISSN 0027-8424

Horne, J, Walko, M, Calabrese, A et al. (5 more authors) (2018) Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers. Angewandte Chemie - International Edition, 57 (51). pp. 16688-16692. ISSN 1433-7851

Horne, JE, Walko, M, Calabrese, AN et al. (5 more authors) (2018) Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers. Angewandte Chemie, 130 (51). pp. 16930-16934. ISSN 0044-8249

Cornwell, O, Radford, SE orcid.org/0000-0001-9668-6366, Ashcroft, AE orcid.org/0000-0002-1676-123X et al. (1 more author) (2018) Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β₂-Microglobulin. Journal of The American Society for Mass Spectrometry, 29 (12). pp. 2413-2426. ISSN 1044-0305

Berry, A orcid.org/0000-0003-3502-0426 and Radford, SE orcid.org/0000-0002-3079-8039 (2018) Richard Nelson Perham. 27 April 1937—14 February 2015. Biographical Memoirs of Fellows of the Royal Society, 65. pp. 317-339. ISSN 0080-4606

Iadanza, MG, Silvers, R, Boardman, J et al. (7 more authors) (2018) The structure of a β₂-microglobulin fibril suggests a molecular basis for its amyloid polymorphism. Nature Communications, 9. 4517. ISSN 2041-1723

Townsend, D, Hughes, E, Stewart, KL et al. (3 more authors) (2018) Orientation of a Diagnostic Ligand Bound to Macroscopically Aligned Amyloid-ß Fibrils Determined by Solid-state NMR. Journal of Physical Chemistry Letters, 9 (22). pp. 6611-6615. ISSN 1948-7185

Iadanza, MG, Jackson, MP, Hewitt, EW orcid.org/0000-0002-6238-6303 et al. (2 more authors) (2018) A new era for understanding amyloid structures and disease. Nature Reviews Molecular Cell Biology, 19 (12). pp. 755-773. ISSN 1471-0072

Calabrese, AN and Radford, SE orcid.org/0000-0002-3079-8039 (2018) Mass spectrometry-enabled structural biology of membrane proteins. Methods, 147. pp. 187-205. ISSN 1046-2023

Doherty, CPA orcid.org/0000-0001-5685-4716, Young, LM, Karamanos, TK et al. (4 more authors) (2018) A peptide‐display protein scaffold to facilitate single molecule force studies of aggregation‐prone peptides. Protein Science, 27 (7). pp. 1205-1217. ISSN 0961-8368

Hethershaw, EL orcid.org/0000-0002-4366-278X, Adamson, PJ, Smith, KA orcid.org/0000-0001-5695-7117 et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933

Fessl, T orcid.org/0000-0001-6969-4870, Watkins, D, Oatley, P et al. (7 more authors) (2018) Dynamic action of the Sec machinery during initiation, protein translocation and termination. eLife, 7. e35112. ISSN 2050-084X

Martin, EM, Jackson, MP, Gamerdinger, M et al. (6 more authors) (2018) Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins. Journal of Biological Chemistry, 293 (22). pp. 8554-8568. ISSN 0021-9258

Townsend, D, Hughes, E, Akien, G et al. (4 more authors) (2018) Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin. Journal of Biological Chemistry, 293 (33). pp. 12877-12893. ISSN 0021-9258

Willis, LF orcid.org/0000-0001-6616-3716, Kumar, A, Dobson, J et al. (6 more authors) (2018) Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules. Biotechnology and Bioengineering, 115 (5). pp. 1216-1225. ISSN 0006-3592

Knight, PD, Karamanos, TK, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2018) Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. European Journal of Mass Spectrometry, 24 (1). pp. 129-140. ISSN 1469-0667

Schiffrin, B, Brockwell, DJ orcid.org/0000-0002-0802-5937 and Radford, SE orcid.org/0000-0002-3079-8039 (2017) Outer membrane protein folding from an energy landscape perspective. BMC Biology, 15 (1). 123. ISSN 1741-7007

Schiffrin, R, Calabrese, AN, Higgins, AJ et al. (5 more authors) (2017) Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding. Journal of Molecular Biology, 429. pp. 3776-3792. ISSN 0022-2836

Devine, PWA, Fisher, HC, Calabrese, AN et al. (6 more authors) (2017) Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. Journal of The American Society for Mass Spectrometry, 28 (9). pp. 1855-1862. ISSN 1044-0305

Calabrese, AN, Jackson, SM, Jones, LN et al. (10 more authors) (2017) Topological dissection of the membrane transport protein Mhp1 derived from cysteine accessibility and mass spectrometry. Analytical Chemistry, 89 (17). pp. 8844-8852. ISSN 0003-2700

Stewart, KL orcid.org/0000-0001-8845-9155, Hughes, E, Yates, EA et al. (2 more authors) (2017) Molecular Origins of the Compatibility Between Glycosaminoglycans and Aβ40 Amyloid Fibrils. Journal of Molecular Biology, 429 (16). pp. 2449-2462. ISSN 0022-2836

Stewart, KL orcid.org/0000-0001-8845-9155 and Radford, SE orcid.org/0000-0002-3079-8039 (2017) Amyloid Plaques Beyond Aβ: A Survey of the Diverse Modulators of Amyloid Aggregation. Biophysical Reviews, 9 (4). pp. 405-419. ISSN 1867-2450

Young, LM, Ashcroft, AE and Radford, SE orcid.org/0000-0002-3079-8039 (2017) Small molecule probes of protein aggregation. Current Opinion in Chemical Biology, 39. pp. 90-99. ISSN 1367-5931

Young, LM, Tu, LH, Raleigh, D et al. (2 more authors) (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science, 8 (7). pp. 5030-5040. ISSN 2041-6520

Dobson, J, Kumar, A, Willis, LF orcid.org/0000-0001-6616-3716 et al. (8 more authors) (2017) Inducing protein aggregation by extensional flow. Proceedings of the National Academy of Sciences, 114 (18). pp. 4673-4678. ISSN 0027-8424

Watkinson, TG, Calabrese, AN, Ault, JR orcid.org/0000-0002-5131-438X et al. (2 more authors) (2017) FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins. Journal of the American Society for Mass Spectrometry, 28 (1). pp. 50-55. ISSN 1044-0305

Dobson, CL, Devine, PWA, Phillips, JJ et al. (24 more authors) (2016) Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Scientific Reports, 6. 38644. ISSN 2045-2322

Iadanza, MG, Higgins, AJ, Schiffrin, R et al. (5 more authors) (2016) Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. Nature Communications, 7. 12865.

Schiffrin, B, Calabrese, AN, Devine, PWA et al. (4 more authors) (2016) Skp is a multivalent chaperone of outer membrane proteins. Nature Structural and Molecular Biology, 23 (9). pp. 786-793. ISSN 1545-9993

Stewart, KL, Hughes, E, Yates, EA et al. (8 more authors) (2016) Atomic Details of the Interactions of Glycosaminoglycans with Amyloid-β Fibrils. Journal of the American Chemical Society, 138 (27). pp. 8328-8331. ISSN 0002-7863

Horne, JE and Radford, SE orcid.org/0000-0002-3079-8039 (2016) A growing toolbox of techniques for studying β-barrel outer membrane protein folding and biogenesis. Biochemical Society Transactions, 44 (3). pp. 802-809. ISSN 0300-5127

Karamanos, TK, Pashley, CL, Kalverda, AP et al. (4 more authors) (2016) A population shift between sparsely populated folding intermediates determines amyloidogenicity. Journal of the American Chemical Society, 138 (19). pp. 6271-6280. ISSN 0002-7863

Allen, WJ, Corey, RA, Oatley, P et al. (5 more authors) (2016) Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation. eLife, 5. e15598. ISSN 2050-084X

Young, LM, Saunders, JC, Mahood, RA et al. (4 more authors) (2016) ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules. Methods, 95. pp. 62-69. ISSN 1046-2023

Pashley, CL, Hewitt, E and Radford, SE (2016) Comparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formation. Journal of Molecular Biology, 428 (3). pp. 631-643. ISSN 0022-2836

Iadanza, MG, Jackson, MP, Radford, SE et al. (1 more author) (2016) MpUL-multi: Software for Calculation of Amyloid Fibril Mass per Unit Length from TB-TEM Images. Scientific Reports, 6. 21078. ISSN 2045-2322

Saunders, JC, Young, LM, Mahood, RA et al. (7 more authors) (2016) An in vivo platform for identifying inhibitors of protein aggregation. Nature Chemical Biology, 12 (2). pp. 94-101. ISSN 1552-4450

Stull, F, Koldewey, P, Humes, JR orcid.org/0000-0002-1407-7880 et al. (2 more authors) (2016) Substrate protein folds while it is bound to the ATP-independent chaperone Spy. Nature Structural & Molecular Biology, 23 (1). pp. 53-58. ISSN 1545-9993

Tipping, KW, Van Oosten-Hawle, P, Hewitt, EW et al. (1 more author) (2015) Amyloid fibres: inert end-stage aggregates or key players in disease? Trends in Biochemical Sciences, 40 (12). pp. 719-727. ISSN 0968-0004

Watkinson, TG, Calabrese, AN, Giusti, F et al. (3 more authors) (2015) Systematic analysis of the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry. International Journal of Mass Spectrometry, 391. pp. 54-61. ISSN 1387-3806

Calabrese, AN, Ault, JR, Radford, SE et al. (1 more author) (2015) Using hydroxyl radical footprinting to explore the free energy landscape of protein folding. Methods, 89. 38 - 44. ISSN 1046-2023

Karamanos, TK, Kalverda, AP, Thompson, GS et al. (1 more author) (2015) Mechanisms of amyloid formation revealed by solution NMR. Progress in Nuclear Magnetic Resonance Spectroscopy, 2015 (88-89). 10.1016/j.pnmrs.2015.05.002. 86 - 104 (17). ISSN 0079-6565

Rajabi, K, Reuther, J, Deuerling, E et al. (2 more authors) (2015) A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry. Protein science : a publication of the Protein Society, 24 (8). 1282 - 1291. ISSN 0961-8368

Young, LM, Mahood, RA, Saunders, JC et al. (4 more authors) (2015) Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry. Analyst, 140. 6990 - 6999. ISSN 0003-2654

Tipping, KW, Karamanos, TK orcid.org/0000-0003-2297-540X, Jakhria, T et al. (6 more authors) (2015) pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers. Proceedings of the National Academy of Sciences, 112 (18). pp. 5691-5696. ISSN 0027-8424

Scarff, CA, Almeida, B, Fraga, J et al. (3 more authors) (2015) Examination of ataxin-3 (atx-3) aggregation by structural mass spectrometry techniques: A rationale for expedited aggregation upon polyglutamine (polyQ) expansion. Molecular and Cellular Proteomics, 14 (5). 1241 - 1253. ISSN 1535-9476

Farrance, OE, Paci, E orcid.org/0000-0002-4891-2768, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2015) Extraction of Accurate Biomolecular Parameters from Single-Molecule Force Spectroscopy Experiments. ACS Nano, 9 (2). pp. 1315-1324. ISSN 1936-0851

Chen, Y, Radford, SE and Brockwell, DJ (2015) Force-induced remodelling of proteins and their complexes. Current Opinion in Structural Biology, 30. 89 - 99. ISSN 0959-440X

Calabrese, AN, Watkinson, TG, Henderson, PJF et al. (2 more authors) (2015) Amphipols outperform dodecylmaltoside micelles in stabilizing membrane protein structure in the gas phase. Analytical Chemistry, 87 (2). 1118 - 1126. ISSN 0003-2700

Young, LM, Saunders, JC, Mahood, RA et al. (6 more authors) (2015) Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry. Nature Chemistry, 7 (1). pp. 73-81. ISSN 1755-4330

Jakhria, T, Hellewell, AL, Porter, MY et al. (5 more authors) (2014) β2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes. Journal of Biological Chemistry, 289 (52). 35781 - 35794. ISSN 0021-9258

McMorran, LM, Brockwell, DJ and Radford, SE (2014) Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date? Archives of Biochemistry and Biophysics, 564. 265 - 280. ISSN 0003-9861

Zhuravleva, A and Radford, SE (2014) How tric folds tricky proteins. Cell, 159 (6). 1251 - 1252. ISSN 0092-8674

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Book Section

Fessl, T, Crossley, JA, Watkins, D et al. (6 more authors) (2021) Dynamics of Membrane Proteins Monitored by Single-Molecule Fluorescence Across Multiple Timescales. In: Postis, VLG and Goldman, A, (eds.) Biophysics of Membrane Proteins: Methods and Protocols. Methods in Molecular Biology, 2168 . Humana , New York, NY , pp. 273-297. ISBN 978-1-0716-0723-7

Scarff, CA orcid.org/0000-0001-6168-0060, Ashcroft, AE orcid.org/0000-0002-1676-123X and Radford, SE orcid.org/0000-0002-3079-8039 (2016) Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS). In: Eliezer, D, (ed.) Protein Amyloid Aggregation: methods and protocols. Methods in Molecular Biology, 1345 . Springer (Humana Press) , New York, N.Y., U.S.A. , pp. 115-132. ISBN 978-1-4939-2977-1