Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedication of anxious children (the MAGIC trial)

Hyslop, M.C. orcid.org/0009-0005-7078-4933, Papaioannou, D.E. orcid.org/0000-0002-6259-0822, Bolt, R. orcid.org/0009-0007-1705-8400 et al. (10 more authors) (2025) Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedication of anxious children (the MAGIC trial). BJA Open, 13. 100375. ISSN 2772-6096

Abstract

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Item Type: Article
Authors/Creators:
Copyright, Publisher and Additional Information:

© 2025 The Author(s). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Keywords: early termination of clinical trials; general anaesthesia; paediatric anxiety; perioperative care; poor recruitment; reasons for recruitment failure
Dates:
  • Submitted: 5 June 2024
  • Accepted: 21 December 2024
  • Published (online): 4 February 2025
  • Published: March 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
The University of Sheffield > Faculty of Social Sciences (Sheffield) > School of Education
Funding Information:
Funder
Grant number
NIHR Evaluation Trials and Studies Coordinating Centre
16/80/08
NATIONAL INSTITUTE FOR HEALTH RESEARCH
16/80/08
Depositing User: Symplectic Sheffield
Date Deposited: 01 Jul 2025 07:29
Last Modified: 01 Jul 2025 07:29
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.bjao.2024.100375
Related URLs:
Sustainable Development Goals:
  • Sustainable Development Goals: Goal 3: Good Health and Well-Being
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