Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times

Abstract

A universal multi-stage cascade CSTR has been developed which is suitable for a wide range of continuous-flow processes. Coined by our group the ‘Freactor’ (free-to-access reactor), the new reactor integrates the efficiency of pipe-flow processing with the advanced mixing of a CSTR, delivering a general ‘plug-and-play’ reactor platform which is well-suited to multiphasic continuous-flow chemistry. Importantly, the reactor geometry is easily customized to accommodate reactions requiring long residence times (≥ 3 hours tested).

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Item Type:	Article
Authors/Creators:	Chapman, MR Kwan, MHT King, G Jolley, KE Hussain, M Hussain, S Salama, IE González Nino, C Thompson, LA https://orcid.org/0000-0003-1128-7927 Bayana, ME https://orcid.org/0000-0001-9613-2937 Clayton, A https://orcid.org/0000-0002-4634-8008 Nguyen, BN https://orcid.org/0000-0002-0254-025X Turner, NJ Kapur, N https://orcid.org/0000-0003-1041-8390 Blacker, AJ https://orcid.org/0000-0003-4898-2712
Copyright, Publisher and Additional Information:	© 2017 American Chemical Society. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
Dates:	Accepted: 11 May 2017 Published (online): 28 June 2017 Published: 15 September 2017
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Engineering Thermofluids, Surfaces & Interfaces (iETSI) (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds)
Funding Information:	Funder Grant number Royal Academy of Engineering GMS100835 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360 EU - European Union 115360
Depositing User:	Symplectic Publications
Date Deposited:	21 Jul 2017 11:54
Last Modified:	20 Jun 2021 08:37
Status:	Published
Publisher:	American Chemical Society
Identification Number:	10.1021/acs.oprd.7b00173
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:119272

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Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times

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