Ismail, S.D., Riou, C., Joseph, S.B. et al. (15 more authors) (2021) Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size. Clinical Infectious Diseases, 73 (8). pp. 1528-1531. ISSN 1058-4838
Abstract
Understanding what shapes the latent human immunodeficiency virus type 1 (HIV-1) reservoir is critical for developing strategies for cure. We measured frequency of persistent HIV-1 infection after 5 years of suppressive antiretroviral therapy initiated during chronic infection. Pretreatment CD8+ T-cell activation, nadir CD4 count, and CD4:CD8 ratio predicted reservoir size.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | HIV-1, replication-competent virus, reservoir, T-cell activation |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mathematics (Leeds) > Applied Mathematics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 17 Feb 2025 10:25 |
Last Modified: | 17 Feb 2025 10:25 |
Status: | Published |
Publisher: | Oxford University Press |
Identification Number: | 10.1093/cid/ciab587 |
Sustainable Development Goals: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:223365 |
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