Mehryar, P, Shourijeh, MS, Rezaeian, T orcid.org/0000-0002-7083-0945 et al. (5 more authors) (2020) Differences in muscle synergies between healthy subjects and transfemoral amputees during normal transient-state walking speed. Gait & Posture, 76. pp. 98-103. ISSN 0966-6362
Abstract
Background
Lower limb amputation is a major public health issue globally, and its prevalence is increasing significantly around the world. Previous studies on lower limb amputees showed analogous complexity implemented by the neurological system which does not depend on the level of amputation.
Research question
What are the differences in muscle synergies between healthy subjects (HS) and transfemoral amputees (TFA) during self-selected normal transient-state walking speed?
Methods
thirteen male HS and eleven male TFA participated in this study. Surface electromyography (sEMG) data were collected from HS dominant leg and TFA intact limb. Concatenated non-negative matrix factorization (CNMF) was used to extract muscle synergy components synergy vectors (S) and activation coefficient profiles (C). Correlation between a pair of synergy vectors from HS and TFA was analyzed by means of the coefficient of determination (R2). Statistical parametric mapping (SPM) was used to compare the temporal components of the muscle synergies between groups.
Results
the highest correlation was perceived in synergy 2 (S2) and 3 (S3) and the lowest in synergy 1 (S1) and 4 (S4) between HS and TFA. Statistically significant differences were observed in all of the activation coefficients, particularly during the stance phase. Significant lag in the activation coefficient of S2 (due mainly to activated plantarflexors) resulted in a statistically larger portion of the gait cycle (GC) in stance phase in TFA.
Significance
Understanding the activation patterns of lower limb amputees’ muscles that control their intact leg (IL) and prosthetic leg (PL) joints could lead to greater knowledge of neuromuscular compensation strategies in amputees. Studying the low-dimensional muscle synergy patterns in the lower limbs can further this understanding. The findings in this study could contribute to improving gait rehabilitation of lower limb amputees and development of the new generation of prostheses.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | Surface electromyography; Muscle synergy/modular motor control; Non-negative matrix factorization; Non-amputees/healthy; Transfemoral/above knee amputees; Transient-state gait; Statistical parametric mapping |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Engineering Systems and Design (iESD) (Leeds) The University of Leeds > Faculty of Biological Sciences (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Rehabilitation Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 21 Apr 2021 15:22 |
Last Modified: | 20 Jun 2021 08:38 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.gaitpost.2019.10.034 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:173144 |