Integrated eicosanoid lipidomics and gene expression reveal decreased prostaglandin catabolism and increased 5‐lipoxygenase expression in aggressive subtypes of endometrial cancer

Cummings, M, Massey, KA, Mappa, G et al. (10 more authors) (2018) Integrated eicosanoid lipidomics and gene expression reveal decreased prostaglandin catabolism and increased 5‐lipoxygenase expression in aggressive subtypes of endometrial cancer. Journal of Pathology, 247 (1). pp. 21-34. ISSN 0022-3417

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Copyright, Publisher and Additional Information: © 2018 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. This is an author produced version of a paper published in Journal of Pathology. Uploaded in accordance with the publisher's self-archiving policy. This article may be used for non-commercial purposes in accordance with the Wiley Terms and Conditions for Self-Archiving.
Keywords: lipidomics; eicosanoids; gene expression; endometrial cancer; cyclooxygenase; COX; LOX; 5-lipoxygenase; 15-PGDH; 15-hydroxyprostaglandin dehydrogenase; prognostic; endometrium
Dates:
  • Accepted: 26 August 2018
  • Published (online): 31 August 2018
  • Published: 17 December 2018
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mathematics (Leeds) > Statistics (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) > Obstetrics & Gynaecology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Pathology & Tumour Biology (Leeds)
Funding Information:
FunderGrant number
Wellbeing of WomenRG1210
Yorkshire Cancer ResearchLPP053
Depositing User: Symplectic Publications
Date Deposited: 31 Aug 2018 10:44
Last Modified: 31 Aug 2019 00:41
Status: Published
Publisher: Wiley
Identification Number: https://doi.org/10.1002/path.5160

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