Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times

Abstract

A universal multi-stage cascade CSTR has been developed which is suitable for a wide range of continuous-flow processes. Coined by our group the ‘Freactor’ (free-to-access reactor), the new reactor integrates the efficiency of pipe-flow processing with the advanced mixing of a CSTR, delivering a general ‘plug-and-play’ reactor platform which is well-suited to multiphasic continuous-flow chemistry. Importantly, the reactor geometry is easily customized to accommodate reactions requiring long residence times (≥ 3 hours tested).

Metadata

Authors/Creators:

Chapman, MR
Kwan, MHT
King, G
Jolley, KE
Hussain, M
Hussain, S
Salama, IE
González Nino, C
Thompson, LA https://orcid.org/0000-0003-1128-7927
Bayana, ME https://orcid.org/0000-0001-9613-2937
Clayton, A https://orcid.org/0000-0002-4634-8008
Nguyen, BN https://orcid.org/0000-0002-0254-025X
Turner, NJ
Kapur, N https://orcid.org/0000-0003-1041-8390
Blacker, AJ https://orcid.org/0000-0003-4898-2712

© 2017 American Chemical Society. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

Dates:

Accepted: 11 May 2017
Published (online): 28 June 2017
Published: 15 September 2017

Institution:

The University of Leeds

Academic Units:

The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds)
The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Mechanical Engineering (Leeds) > Institute of Engineering Thermofluids, Surfaces & Interfaces (iETSI) (Leeds)
The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds)

Funding Information:

Funder	Grant number
Royal Academy of Engineering	GMS100835
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360
EU - European Union	115360

Depositing User:

Symplectic Publications

Date Deposited:

21 Jul 2017 11:54

Last Modified:

20 Jun 2021 08:37

Status:

Published

Publisher:

American Chemical Society

Identification Number:

https://doi.org/10.1021/acs.oprd.7b00173

CORE (COnnecting REpositories)

Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times

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