Items where authors include "Vocadlo, David J."

Article

Alteen, Matthew G., Meek, Richard W., Kolappan, Subramania et al. (7 more authors) (2023) Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase. PNAS. e2303690120. ISSN 1091-6490

Calvelo, Martín, Males, Alexandra orcid.org/0000-0002-7250-8300, Alteen, Matthew G. et al. (4 more authors) (2023) Human O-GlcNAcase Uses a Preactivated Boat-like Substrate Conformation for Catalysis : Evidence from X-ray Crystallography and QM/MM Metadynamics. ACS Catalysis. 13672–13678. ISSN 2155-5435

Doherty, Gareth G., Ler, Geraldine Jia Ming, Wimmer, Norbert et al. (9 more authors) (2023) Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase**. Chembiochem. e202200619. ISSN 1439-7633

Alteen, Matthew G., Peacock, Hayden, Meek, Richard W. et al. (5 more authors) (2023) Potent De Novo Macrocyclic Peptides That Inhibit O-GlcNAc Transferase through an Allosteric Mechanism. Angewandte Chemie - International Edition. e202215671. ISSN 1433-7851

González-Cuest, Manuel, Sidhu, Peter, Ashmus, Roger A. et al. (10 more authors) (2022) Bicyclic picomolar OGA inhibitors enable chemoproteomic mapping of its endogenous post-translational modifications. Journal of the American Chemical Society. 832–844. ISSN 1520-5126

Meek, Richard W., Blaza, James N. orcid.org/0000-0001-5420-2116, Busmann, Jil A. et al. (3 more authors) (2021) Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT. Nature Communications. 6508. ISSN 2041-1723

Alteen, Matthew G., Gros, Christina, Meek, Richard W. et al. (11 more authors) (2020) A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High‐Throughput Screening : Application to O‐GlcNAc Transferase. Angewandte Chemie International Edition. pp. 9601-9609. ISSN 1433-7851

Deen, Matthew C., Proceviat, Cameron, Shan, Xiaoyang et al. (4 more authors) (2020) Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates. ACS Chemical Biology. ISSN 1554-8937

Tan, Hong Yee, Eskandari, Razieh, Shen, David et al. (6 more authors) (2018) Direct One-Step Fluorescent Labeling of O-GlcNAc-Modified Proteins in Live Cells Using Metabolic Intermediates. Journal of the American Chemical Society. pp. 15300-15308. ISSN 1520-5126

Roth, Christian orcid.org/0000-0001-5806-0987, Chan, Oi Yi, Offen, Wendy Anne orcid.org/0000-0002-2758-4531 et al. (7 more authors) (2017) Structural and functional insight into human O-GlcNAcase. NATURE CHEMICAL BIOLOGY. pp. 610-612. ISSN 1552-4450