Items where authors include "Southam, H.M."

Article

Varney, A.M. orcid.org/0000-0002-5943-161X, Smitten, K.L., Southam, H.M. et al. (4 more authors) (2024) In vitro and in vivo studies on a mononuclear ruthenium complex reveals it is a highly effective, fast-acting, broad-spectrum antimicrobial in physiologically relevant conditions. ACS Infectious Diseases, 10 (9). pp. 3346-3357. ISSN 2373-8227

Smitten, K., Southam, H.M., Fairbanks, S. et al. (3 more authors) (2023) Clearing an ESKAPE pathogen in a model organism; a polypyridyl ruthenium(II) complex theranostic that treats a resistant Acinetobacter baumannii infection in Galleria mellonella. Chemistry – A European Journal, 29 (11). e202203555. ISSN 0947-6539

Lyon, R.F., Southam, H.M., Trevitt, C.R. et al. (4 more authors) (2022) CORM-3 induces DNA damage through Ru(II) binding to DNA. Biochemical Journal, 479 (13). pp. 1429-1439. ISSN 0264-6021

Southam, H.M., Williamson, M.P. orcid.org/0000-0001-5572-1903, Chapman, J.A. et al. (4 more authors) (2021) ‘Carbon-monoxide-releasing molecule-2 (CORM-2)’ is a misnomer: ruthenium toxicity, not CO release, accounts for Its antimicrobial effects. Antioxidants, 10 (6). 915. ISSN 2076-3921

Betts, J.W., Roth, P., Pattrick, C.A. et al. (4 more authors) (2020) Antibacterial activity of Mn(i) and Re(i) tricarbonyl complexes conjugated to a bile acid carrier molecule. Metallomics, 12 (10). pp. 1563-1575. ISSN 1756-5901

Smitten, K.L., Thick, E.J., Southam, H.M. et al. (3 more authors) (2020) Mononuclear ruthenium(ii) theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA. Chemical Science, 11 (33). pp. 8828-8838. ISSN 2041-6520

Smitten, K.L., Southam, H.M., de la Serna, J.B. orcid.org/0000-0002-1396-3338 et al. (5 more authors) (2019) Using nanoscopy to probe the biological activity of antimicrobial leads that display potent activity against pathogenic, multidrug resistant, gram-negative bacteria. ACS Nano, 13 (5). pp. 5133-5146. ISSN 1936-0851

Wareham, L.K., Southam, H.M. and Poole, R.K. orcid.org/0000-0002-4664-6689 (2018) Do nitric oxide, carbon monoxide and hydrogen sulfide really qualify as 'gasotransmitters' in bacteria? Biochemical Society Transactions, 46 (5). pp. 1107-1118. ISSN 0300-5127

Liu, X., Sun, B., Kell, R.E.M. et al. (6 more authors) (2018) The Antimicrobial Activity of Mononuclear Ruthenium(II) Complexes Containing the dppz Ligand. ChemPlusChem, 83 (7). pp. 643-650.

Southam, H.M., Smith, T.W., Lyon, R.L. et al. (10 more authors) (2018) A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3. Redox Biology, 18. pp. 114-123.

Sun, B., Southam, H.M., Butler, J.A. et al. (5 more authors) (2018) Synthesis, isomerisation and biological properties of mononuclear ruthenium complexes containing the bis[4(4 '-methyl-2,2 '-bipyridyl)]-1,7-heptane ligand. Dalton Transactions, 47 (7). pp. 2422-2434. ISSN 1477-9226