Items where authors include "Rudd, S.G."
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Zhang, S.M., Paulin, C.B.J., Shu, H. et al. (24 more authors) (2024) Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel. iScience, 27 (2). 108907. ISSN 2589-0042
Helleday, T. and Rudd, S.G. (2022) Targeting the DNA damage response and repair in cancer through nucleotide metabolism. Molecular Oncology, 16 (21). pp. 3792-3810. ISSN 1574-7891
Rehling, D., Zhang, S.M., Jemth, A.-S. et al. (15 more authors) (2021) Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity. Journal of Biological Chemistry, 296. 100568. ISSN 0021-9258
Zhang, S.M., Desroses, M., Hagenkort, A. et al. (34 more authors) (2020) Development of a chemical probe against NUDT15. Nature Chemical Biology, 16 (10). pp. 1120-1128. ISSN 1552-4450
Rudd, S.G., Gad, H. orcid.org/0000-0001-6530-1443, Sanjiv, K. et al. (7 more authors) (2020) MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG. Cancer Research, 80 (17). pp. 3530-3541. ISSN 0008-5472
Herr, P. orcid.org/0000-0003-2945-966X, Boström, J., Rullman, E. et al. (6 more authors) (2020) Cell cycle profiling reveals protein oscillation, phosphorylation, and localization dynamics. Molecular & Cellular Proteomics, 19 (4). pp. 608-623. ISSN 1535-9476
Rudd, S.G., Tsesmetzis, N., Sanjiv, K. et al. (32 more authors) (2020) Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy. EMBO Molecular Medicine, 12 (3). e10419. ISSN 1757-4676
Rudd, S.G. orcid.org/0000-0002-4368-3855, Gad, H., Amaral, N. et al. (6 more authors) (2019) MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression. bioRxiv. (Submitted)
Page, B.D.G., Valerie, N.C.K., Wright, R.H.G. et al. (22 more authors) (2018) Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nature Communications, 9 (1). 250. ISSN 2041-1723
Eshtad, S., Mavajian, Z., Rudd, S.G. et al. (4 more authors) (2016) hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia. Oncogenesis, 5 (12). e275. ISSN 2157-9024