Items where authors include "Renshaw, S.A."

Article

Tooke, A.K. orcid.org/0000-0002-8719-5263, Hodges, R.E. orcid.org/0000-0001-6805-1523, Pyrah, J.F. orcid.org/0000-0002-4299-2488 et al. (3 more authors) (2024) Tetracycline and oxacillin act synergistically on biofilms and display increased efficacy in vivo against staphylococcus aureus. Current Microbiology, 81. 447. ISSN 0343-8651

Hibbert, T.M., Whiteley, M., Renshaw, S.A. orcid.org/0000-0003-1790-1641 et al. (2 more authors) (2024) Emerging strategies to target virulence in Pseudomonas aeruginosa respiratory infections. Critical Reviews in Microbiology, 50 (6). pp. 1037-1052. ISSN 1040-841X

Alves, J. orcid.org/0000-0003-3131-9834, Vrieling, M., Ring, N. et al. (5 more authors) (2024) Experimental evolution of Staphylococcus aureus in macrophages: dissection of a conditional adaptive trait promoting intracellular survival. mBio, 15 (6). e0034624. ISSN 2150-7511

Rutherford, H.A., Candeias, D. orcid.org/0009-0001-9108-4929, Duncan, C.J.A. orcid.org/0000-0003-4181-2315 et al. (2 more authors) (2024) Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model. Proceedings of the National Academy of Sciences, 121 (21). e2321496121. ISSN 0027-8424

Speirs, Z.C., Loynes, C.A., Mathiessen, H. et al. (3 more authors) (2024) What can we learn about fish neutrophil and macrophage response to immune challenge from studies in zebrafish. Fish & Shellfish Immunology, 148. 109490. ISSN 1050-4648

Jubber, I. orcid.org/0000-0002-4558-2521, Morhardt, D.R., Griffin, J. orcid.org/0000-0003-3969-7637 et al. (10 more authors) (2023) Analysis of the distal urinary tract in larval and adult zebrafish reveals homology to the human system. Disease Models & Mechanisms, 16 (7). dmm050110. ISSN 1754-8403

Morsli, S. orcid.org/0000-0002-0371-0732, Henriques, C.M. orcid.org/0000-0003-1882-756X, Ellis, P.S. et al. (5 more authors) (2023) A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo. Aging Cell, 22 (6). e13835. ISSN 1474-9718

Elworthy, S. orcid.org/0000-0002-9739-1540, Rutherford, H.A. orcid.org/0000-0002-6227-0271, Prajsnar, T.K. orcid.org/0000-0001-6562-8630 et al. (4 more authors) (2023) Activated PI3K Delta Syndrome-1 mutations cause neutrophilia in zebrafish larvae. Disease Models & Mechanisms, 16 (3). dmm049841. ISSN 1754-8403

Pidwill, G.R., Pyrah, J.F., Sutton, J.A.F. orcid.org/0000-0002-0440-610X et al. (3 more authors) (2023) Clonal population expansion of Staphylococcus aureus occurs due to escape from a finite number of intraphagocyte niches. Scientific Reports, 13 (1). 1188. pp. 1-11.

Herman, K.D., Wright, C.G., Marriott, H.M. orcid.org/0000-0003-1070-0054 et al. (5 more authors) (2022) The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages. Frontiers in Immunology, 13. 956991. ISSN 1664-3224

Ellis, P.S., Martins, R.R., Thompson, E.J. et al. (3 more authors) (2022) A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish. Immunity & Ageing, 19 (1). 31. ISSN 1742-4933

Prajsnar, T.K., Michno, B.J., Pooranachandran, N. et al. (4 more authors) (2022) Phagosomal acidification Is required to kill Streptococcus pneumoniae in a Zebrafish model. Cellular Microbiology, 2022. 9429516. ISSN 1462-5814

Gibson, J.F., Bojarczuk, A., Evans, R.J. et al. (7 more authors) (2022) Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection. PLoS Pathogens, 18 (4). e1010389. ISSN 1553-7366

Rutherford, H.A., Clarke, A., Chambers, E.V. et al. (7 more authors) (2022) A zebrafish reporter line reveals immune and neuronal expression of endogenous retrovirus. Disease Models & Mechanisms, 15 (4). dmm048921. ISSN 1754-8403

Salamaga, B., Kong, L., Pasquina-Lemonche, L. et al. (17 more authors) (2021) Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics. Proceedings of the National Academy of Sciences, 118 (44). e2106022118. ISSN 0027-8424

Gibson, J.F., Pidwill, G.R. orcid.org/0000-0002-5193-3631, Carnell, O.T. et al. (13 more authors) (2021) Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species. PLoS Pathogens, 17 (9). e1009880. ISSN 1553-7366

Isles, H.M., Loynes, C.A., Alasmari, S. et al. (11 more authors) (2021) Pioneer neutrophils release chromatin within in vivo swarms. eLife, 10. e68755.

Gibson, J.F., Prajsnar, T.K., Hill, C.J. et al. (8 more authors) (2021) Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish. Autophagy, 17 (6). pp. 1448-1457. ISSN 1554-8627

Sutton, J.A.F., Carnell, O.T., Lafage, L. orcid.org/0000-0002-8105-5083 et al. (13 more authors) (2021) Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction. PLoS Pathogens, 17 (3). e1009468. ISSN 1553-7366

Pidwill, G.R. orcid.org/0000-0002-5193-3631, Gibson, J.F. orcid.org/0000-0002-4299-2488, Cole, J. et al. (2 more authors) (2021) The role of macrophages in Staphylococcus aureus infection. Frontiers in Immunology, 11. 620339. ISSN 1664-3224

Weatherley, N.D. orcid.org/0000-0001-5589-2219, Eaden, J.A., Hughes, P.J.C. et al. (7 more authors) (2021) Quantification of pulmonary perfusion in idiopathic pulmonary fibrosis with first pass dynamic contrast-enhanced perfusion MRI. Thorax, 76 (2). pp. 144-151. ISSN 1468-3296

Foulkes, M.J., Tolliday, F.H., Henry, K.M. et al. (2 more authors) (2020) Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish. PLOS ONE, 15 (10). e0240231.

Bernut, A., Loynes, C.A., Floto, R.A. et al. (1 more author) (2020) Deletion of cftr leads to an excessive neutrophilic response and defective tissue repair in a zebrafish model of sterile inflammation. Frontiers in Immunology, 11 (1). 1733.

Fenaroli, F., Robertson, J.D., Scarpa, E. et al. (16 more authors) (2020) Polymersomes eradicating intracellular bacteria. ACS Nano, 14 (7). pp. 8287-8298. ISSN 1936-0851

Hamilton, N. orcid.org/0000-0002-3299-9133, Rutherford, H.A., Petts, J.J. et al. (6 more authors) (2020) The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2-deficient leukoencephalopathy. Glia, 68 (7). pp. 1531-1545. ISSN 0894-1491

Eaden, J.A. orcid.org/0000-0002-9314-7233, Barber, C.M., Renshaw, S.A. orcid.org/0000-0003-1790-1641 et al. (2 more authors) (2020) Real world experience of response to pirfenidone in patients with idiopathic pulmonary fibrosis: a two centre retrospective study. Sarcoidosis Vasculitis and Diffuse Lung Diseases, 37 (2). pp. 218-224. ISSN 1124-0490

Watson, K., Russell, C.D., Baillie, J.K. et al. (6 more authors) (2020) Developing novel host-based therapies targeting microbicidal responses in macrophages and neutrophils to combat bacterial antimicrobial resistance. Frontiers in Immunology, 11. 786.

Plant, T., Eamsamarng, S., Sanchez-Garcia, M.A. et al. (20 more authors) (2020) Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. Journal of Clinical Investigation, 130 (6). pp. 3221-3237. ISSN 0021-9738

Prajsnar, T.K., Serba, J.J., Dekker, B.M. et al. (6 more authors) (2020) The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils. Autophagy, 17 (4). pp. 888-902. ISSN 1554-8627

Batalha, I.L. orcid.org/0000-0002-7917-3865, Bernut, A., Schiebler, M. et al. (10 more authors) (2019) Polymeric nanobiotics as a novel treatment for mycobacterial infections. Journal of Controlled Release, 314. pp. 116-124. ISSN 0168-3659

Rahman, A., Henry, K.M., Herman, K.D. et al. (17 more authors) (2019) Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation. eLife, 8. 50990.

Hamilton, N. orcid.org/0000-0002-3299-9133, Rutherford, H.A., Isles, H.M. et al. (6 more authors) (2019) Failure to clear developmental apoptosis contributes to the pathology of RNASET2-deficient leukoencephalopathy. bioRxiv. (Submitted)

Isles, H.M., Herman, K.D., Robertson, A.L. et al. (4 more authors) (2019) The CXCL12/CXCR4 signaling axis retains neutrophils at inflammatory sites in zebrafish. Frontiers in Immunology, 10. 1784.

Buchan, K.D. orcid.org/0000-0002-1934-3287, Prajsnar, T.K. orcid.org/0000-0001-6562-8630, Ogryzko, N.V. orcid.org/0000-0003-0199-5567 et al. (6 more authors) (2019) A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase. PLoS ONE, 14 (4). e0215592. ISSN 1932-6203

Weatherley, N.D. orcid.org/0000-0001-5589-2219, Stewart, N.J., Chan, H.-F. et al. (9 more authors) (2019) Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF. Thorax, 74 (5). pp. 500-502. ISSN 0040-6376

Evans, R.J. orcid.org/0000-0003-0678-6510, Pline, K. orcid.org/0000-0002-6415-7141, Loynes, C.A. orcid.org/0000-0002-7163-4938 et al. (11 more authors) (2019) 15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection. PLoS Pathogens, 15 (3). e1007597. ISSN 1553-7366

Bernut, A. orcid.org/0000-0002-1928-8329, Dupont, C., Ogryzko, N.V. et al. (5 more authors) (2019) CFTR protects against Mycobacterium abscessus infection by fine-tuning host oxidative defenses. Cell Reports, 26 (7). 1828-1840.e4. ISSN 2211-1247

Ogryzko, N.V. orcid.org/0000-0003-0199-5567, Lewis, A. orcid.org/0000-0002-1156-3592, Wilson, H.L. orcid.org/0000-0002-7892-3425 et al. (3 more authors) (2019) Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish. Journal of Immunology, 202 (2). pp. 494-502. ISSN 0022-1767

Loynes, C., Lee, J., Robertson, A. et al. (6 more authors) (2018) PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo. Science Advances, 4 (9). eaar8320. ISSN 2375-2548

Boldock, E. orcid.org/0000-0001-7150-7990, Surewaard, B.G.J., Shamarina, D. et al. (15 more authors) (2018) Human skin commensals augment Staphylococcus aureus pathogenesis. Nature Microbiology, 3 (8). pp. 881-890. ISSN 2058-5276

Hamilton, N. orcid.org/0000-0002-3299-9133, Sabroe, I. orcid.org/0000-0001-9750-8975 and Renshaw, S.A. orcid.org/0000-0003-1790-1641 (2018) A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models. F1000Research, 7 (594). ISSN 2046-1402

Lee, J.A., Chico, T.J.A. orcid.org/0000-0002-7458-5481 and Renshaw, S.A. (2017) The triune of intestinal microbiome, genetics and inflammatory status and its impact on lower gastrointestinal anastomosis healing. FEBS Journal, 285 (7). pp. 1212-1225. ISSN 1742-464X

Connolly, J., Boldock, E., Prince, L.R. et al. (3 more authors) (2017) The identification of Staphylococcus aureus factors required for pathogenicity and growth in human blood. Infection and Immunity, 85 (11). ISSN 0019-9567

Prince, L.R., Dannewitz Prosseda, S., Higgins, K. et al. (10 more authors) (2017) NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival. Blood, 130 (8). pp. 1014-1025. ISSN 0006-4971

Salamaga, B., Prajsnar, T.K., Jareño-Martinez, A. et al. (8 more authors) (2017) Bacterial size matters: multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis. PLoS Pathogens, 13 (7). e1006526. ISSN 1553-7366

Robertson, J.D., Ward, J.R., Avila-Olias, M. et al. (2 more authors) (2017) Targeting Neutrophilic Inflammation using Polymersome-Mediated Cellular Delivery. Journal of Immunology, 189 (9). pp. 3596-3604. ISSN 0022-1767

Robertson, J.D., Rizzello, L., Avila-Olias, M. et al. (5 more authors) (2016) Purification of Nanoparticles by Size and Shape. Scientific Reports, 6. 27494. ISSN 2045-2322

Robertson, A., Ogryzko, N., Henry, K. et al. (14 more authors) (2016) Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen. Disease Models and Mechanisms, 9 (6). pp. 621-632. ISSN 1754-8403

Bojarczuk, A., Miller, K.A., Hotham, R. et al. (9 more authors) (2016) Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection. Scientific Reports, 6. 21489. ISSN 2045-2322

Keatinge, M., Bui, H., Menke, A. et al. (23 more authors) (2015) Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Human Molecular Genetics, 24 (23). pp. 6640-6652. ISSN 0964-6906

Messad, N., Prajsnar, T.K., Lina, G. et al. (9 more authors) (2015) Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers. Diabetes, 64 (8). pp. 2991-2995. ISSN 0012-1797

Schiebler, M., Brown, K., Hegyi, K. et al. (19 more authors) (2015) Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion. EMBO Molecular Medicine, 7 (2). 127 - 139. ISSN 1757-4676

Hepburn, L., Prajsnar, T.K., Klapholz, C. et al. (29 more authors) (2014) A Spaetzle-like role for nerve growth factor beta in vertebrate immunity to Staphylococcus aureus. SCIENCE, 346 (6209). pp. 641-646. ISSN 0036-8075

Candel, S., de Oliveira, S., Lopez-Munoz, A. et al. (11 more authors) (2014) Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress-Induced Inflammation. PLoS Biology, 12 (5). ISSN 1545-7885

McVicker, G., Prajsnar, T.K., Williams, A. et al. (4 more authors) (2014) Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention. PLoS Pathogens, 10 (2). ARTN e1003959. ISSN 1553-7366

Robertson, A.L., Holmes, G.R., Bojarczuk, A.N. et al. (18 more authors) (2014) A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism. Science Translational Medicine , 6 (225). 225ra29. ISSN 1946-6234

Ogryzko, N.V., Hoggett, E.E., Solaymani-Kohal, S. et al. (4 more authors) (2014) Zebrafish tissue injury causes upregulation of interleukin-1 and caspase-dependent amplification of the inflammatory response. Disease Models & Mechanisms, 7 (2). pp. 259-264. ISSN 1754-8403

Wang, X., Robertson, A.L., Li, J. et al. (9 more authors) (2014) Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. Disease Models & Mechanisms, 7 (1). pp. 163-169. ISSN 1754-8403

Elks, P.M., Brizee, S., van der Vaart, M. et al. (4 more authors) (2013) Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism. PLoS Pathogens, 9 (12). ISSN 1553-7374

Henry, K.M., Pase, L., Ramos-Lopez, C.F. et al. (3 more authors) (2013) PhagoSight: An Open-Source MATLAB (R) Package for the Analysis of Fluorescent Neutrophil and Macrophage Migration in a Zebrafish Model. PLoS ONE, 8 (8). e72636. ISSN 1932-6203

Prajsnar, T.K., Hamilton, R., Garcia-Lara, J. et al. (5 more authors) (2012) A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model. Cellular Microbiology, 14 (10). pp. 1600-1619. ISSN 1462-5814

Kadirkamanathan, V. orcid.org/0000-0002-4243-2501, Anderson, S.R., Billings, S.A. et al. (5 more authors) (2012) The Neutrophil's Eye-View: Inference and Visualisation of the Chemoattractant Field Driving Cell Chemotaxis In Vivo. PLoS ONE, 7 (4). ARTN e35182. ISSN 1932-6203

McGrath, E.E., Lawrie, A., Marriott, H.M. et al. (11 more authors) (2012) Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis. Thorax, 67 (9). 796 - 803. ISSN 0040-6376

Holmes, G.R., Dixon, G., Anderson, S.R. et al. (6 more authors) (2012) Drift-Diffusion Analysis of Neutrophil Migration during Inflammation Resolution in a Zebrafish Model. Advances in Hematology, 2012. 792163.

Dixon, G., Elks, P.M. orcid.org/0000-0003-1683-0749, Loynes, C.A. et al. (2 more authors) (2012) A method for the in vivo measurement of zebrafish tissue neutrophil lifespan. ISRN Hematology, 2012. 915868. ISSN 2090-441X

Wardle, D.J., Burgon, J., Sabroe, I. et al. (3 more authors) (2011) Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation. Plos One, 6 (1). Art no.e15768. ISSN 1932-6203

Ward, J.R., Heath, P.R., Catto, J.W. et al. (3 more authors) (2011) Regulation of neutrophil senescence by microRNAs. Plos One, 6 (1). Art no.e15810. ISSN 1932-6203

Gray, C., Loynes, C.A., Whyte, M.K.B. et al. (3 more authors) (2011) Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish. Thrombosis and Haemostasis, 105 (5). pp. 811-819. ISSN 0340-6245

Renshaw, S.A. and Ingham, P.W. (2010) Zebrafish models of the immune response: taking it on the ChIn. BMC Biology, 8. 148. ISSN 1741-7007

Proceedings Paper

Eaden, J.A. orcid.org/0000-0002-9314-7233, Chan, H.-F. orcid.org/0000-0002-5382-2097, Hughes, P.J.C. orcid.org/0000-0002-7979-5840 et al. (15 more authors) (2019) S125 Quantitative CT and hyperpolarised 129-xenon diffusion-weighted MRI in interstitial lung disease. In: Thorax. British Thoracic Society Winter Meeting 2019, 04-06 Dec 2019, Westminster, London, United Kingdom. BMJ Publishing Group Ltd and British Thoracic Society , a79.

Weatherley, N.D. orcid.org/0000-0001-5589-2219, Stewart, N.J., Chan, H.F. orcid.org/0000-0002-5382-2097 et al. (10 more authors) (2018) Probing diffusion and perfusion in idiopathic pulmonary fibrosis with hyperpolarised xenon and dynamic contrast-enhanced magnetic resonance imaging. In: Thorax. British Thoracic Society Winter Meeting 2018, 05-07 Dec 2018, London, UK. BMJ Publishing , A44-A45.

Kadochnikova, A., Isles, H.M., Renshaw, S.A. orcid.org/0000-0003-1790-1641 et al. (1 more author) (2018) Estimation of hidden chemoattractant field from observed cell migration patterns. In: Rojas, C., (ed.) IFAC-PapersOnLine. 18th IFAC Symposium on System Identification SYSID 2018, 09-11 Jul 2018, Stockholm, Sweden. IFAC , pp. 766-771.

Weatherley, N. orcid.org/0000-0001-5589-2219, Chan, H.-F. orcid.org/0000-0002-5382-2097, Stewart, N. et al. (9 more authors) (2017) Late breaking abstract - Hyperpolarised gas MRI demonstrates sub-clinical progression in IPF over 6 months. In: European Respiratory Journal. ERS International Congress 2017, 09-13 Sep 2017, Milan, Italy. European Respiratory Society .

Plant, T., Eamsamarng, S., Loynes, C. et al. (4 more authors) (2014) The Role Of Semaphorin3f (sema3f) In Neutrophilic Inflammation. In: American Journal of Respiratory and Critical Care Medicine. American Thoracic Society 2014 International Conference, 16-21 May 2014, San Diego. American Thoracic Society .