Items where authors include "Pollard, A.J."

Article

Booth, J.S., Rapaka, R.R., McArthur, M.A. et al. (8 more authors) (2024) Role of circulating T follicular helper subsets following Ty21a immunization and oral challenge with wild type S. Typhi in humans. Frontiers in Immunology, 15. 1384642. ISSN 1664-3224

Toapanta, F.R., Hu, J., Shirey, K.A. et al. (6 more authors) (2024) Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria. Frontiers in Immunology, 15. 1454857. ISSN 1664-3224

Dyson, Z.A. orcid.org/0000-0002-8887-3492, Ashton, P.M., Khanam, F. et al. (39 more authors) (2024) Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study. The Lancet Microbe, 5 (8). 100841. ISSN 2666-5247

Meiring, J.E. orcid.org/0000-0001-9183-5174, Khanam, F., Basnyat, B. et al. (12 more authors) (2023) Typhoid fever. Nature Reviews Disease Primers, 9 (1). 71. ISSN 2056-676X

Barnes, M.V.C. orcid.org/0000-0001-5474-3262, Mandla, A., Smith, E. et al. (37 more authors) (2023) Human infection challenge in the pandemic era and beyond, HIC-Vac annual meeting report, 2022. Immunotherapy Advances, 3 (1). ltad024. ISSN 2732-4303

Barton, A. orcid.org/0000-0001-8313-8643, Hill, J., O'Connor, D. et al. (11 more authors) (2023) Early transcriptional responses to human enteric fever challenge. Infection and Immunity, 19 (10). e0010823. ISSN 0019-9567

Fachrul, M. orcid.org/0000-0003-2199-5900, Karkey, A., Shakya, M. et al. (44 more authors) (2023) Direct inference and control of genetic population structure from RNA sequencing data. Communications Biology, 6 (1). 804. ISSN 2399-3642

Moore, S.C. orcid.org/0000-0001-8610-2806, Kronsteiner, B., Longet, S. et al. (61 more authors) (2023) Evolution of long-term vaccine-induced and hybrid immunity in healthcare workers after different COVID-19 vaccine regimens. Med, 4 (3). 191-215.e9. ISSN 2666-6340

Huo, J., Dijokaite-Guraliuc, A., Liu, C. et al. (34 more authors) (2023) A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75. Cell Reports, 42 (1). 111903. ISSN 2211-1247

Mentzer, A.J. orcid.org/0000-0002-4502-2209, O’Connor, D. orcid.org/0000-0002-6902-9886, Bibi, S. et al. (66 more authors) (2023) Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection. Nature Medicine, 29 (1). pp. 147-157. ISSN 1078-8956

Salerno-Gonçalves, R., Fresnay, S., Magder, L. et al. (7 more authors) (2022) Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever. Cellular Immunology, 378. 104572. ISSN 0008-8749

Barton, A., Hill, J., Bibi, S. et al. (12 more authors) (2022) Genetic susceptibility to enteric fever in experimentally challenged human volunteers. Infection and Immunity, 90 (4). ISSN 0019-9567

Khanam, F., Darton, T.C. orcid.org/0000-0003-2209-9956, Meiring, J.E. et al. (8 more authors) (2021) Salmonella Typhi stool shedding by enteric fever patients and asymptomatic chronic carriers in an endemic urban setting. Journal of Infectious Diseases, 224 (Supplement_7). S759-S763. ISSN 0022-1899

Meiring, J.E. orcid.org/0000-0001-9183-5174, Shakya, M., Khanam, F. et al. (20 more authors) (2021) Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study. The Lancet Global Health, 9 (12). e1688-e1696. ISSN 2572-116X

Phillips, M.T., Meiring, J.E. orcid.org/0000-0001-9183-5174, Voysey, M. et al. (14 more authors) (2021) A Bayesian approach for estimating typhoid fever incidence from large‐scale facility‐based passive surveillance data. Statistics in Medicine, 40 (26). pp. 5853-5870. ISSN 0277-6715

Khanam, F., Darton, T.C. orcid.org/0000-0003-2209-9956, Ross, A.G.P. et al. (4 more authors) (2021) Case report : typhoid fever complicated by ileal perforation in an urban slum of Dhaka, Bangladesh. The American Journal of Tropical Medicine and Hygiene, 104 (5). pp. 1755-1757. ISSN 0002-9637

Ramasamy, M.N., Minassian, A.M., Ewer, K.J. et al. (418 more authors) (2020) Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial. The Lancet, 396 (10267). pp. 1979-1993. ISSN 0140-6736

Thindwa, D., Farooq, Y.G., Shakya, M. et al. (8 more authors) (2020) Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia [version 2; peer review: 2 approved, 2 approved with reservations]. Wellcome Open Research, 5. 66. ISSN 2398-502X

Gibani, M.M., Jin, C., Shrestha, S. et al. (22 more authors) (2020) Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model. PLOS Neglected Tropical Diseases, 14 (10). e0008783. ISSN 1935-2727

Rapaka, R.R, Wahid, R., Fresnay, S. et al. (7 more authors) (2020) Human Salmonella Typhi exposure generates differential multifunctional cross‐reactive T‐cell memory responses against Salmonella Paratyphi and invasive nontyphoidal Salmonella. Clinical & Translational Immunology, 9 (9). e1178. ISSN 2050-0068

Carey, M.E., MacWright, W.R., Im, J. et al. (36 more authors) (2020) The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) population-based enteric fever studies: a review of methodological similarities and differences. Clinical Infectious Diseases, 71 (Supplement_2). S102-S110. ISSN 1058-4838

Carter, M.J., Gurung, P., Jones, C. et al. (22 more authors) (2020) Assessment of an antibody-in-lymphocyte supernatant assay for the etiological diagnosis of pneumococcal pneumonia in children. Frontiers in Cellular and Infection Microbiology, 9. 459.

Meiring, J.E. orcid.org/0000-0001-9183-5174, Giubilini, A., Savulescu, J. et al. (2 more authors) (2019) Generating the evidence for typhoid vaccine introduction: considerations for global disease burden estimates and vaccine testing through human challenge. Clinical Infectious Diseases, 69 (Supplement_5). S402-S407. ISSN 1058-4838

Oguti, B., Gibani, M., Darlow, C. et al. (7 more authors) (2019) Factors influencing participation in controlled human infection models : a pooled analysis from six enteric fever studies [under peer review]. Wellcome Open Research, 4. 153.

Blohmke, C.J., Muller, J., Gibani, M.M. et al. (15 more authors) (2019) Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases. EMBO Molecular Medicine, 11 (10). e10431. ISSN 1757-4676

Gibani, M.M., Voysey, M., Jin, C. et al. (13 more authors) (2018) The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies. Clinical Infectious Diseases, 68 (8). pp. 1265-1273. ISSN 1058-4838

Zhang, Y., Brady, A., Jones, C. et al. (9 more authors) (2018) Compositional and functional differences in the human gut microbiome correlate with clinical outcome following infection with wild-type Salmonella enterica serovar Typhi. mBio, 9 (3). e00686-18. ISSN 2150-7511

Juel, H.B., Thomaides-Brears, H.B., Darton, T.C. orcid.org/0000-0003-2209-9956 et al. (12 more authors) (2018) Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model. Frontiers in Immunology, 8. 1916.

Jin, C., Gibani, M.M., Moore, M. et al. (13 more authors) (2017) Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial. The Lancet, 390 (10111). pp. 2472-2480. ISSN 0140-6736

Darton, T.C. orcid.org/0000-0003-2209-9956, Jones, C., Dongol, S. et al. (12 more authors) (2017) Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal. Frontiers in Microbiology, 8. 2031.

Blohmke, C.J., Hill, J., Darton, T.C. orcid.org/0000-0003-2209-9956 et al. (8 more authors) (2017) Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever. Frontiers in Immunology, 8. 1276. ISSN 1664-3224

Darton, T.C. orcid.org/0000-0003-2209-9956, Baker, S., Randall, A. et al. (18 more authors) (2017) Identification of novel serodiagnostic signatures of typhoid fever using a Salmonella proteome array. Frontiers in Microbiology, 8. 1794. ISSN 1664-302X

Meiring, J.E., Gibani, M., Basnyat, B. et al. (23 more authors) (2017) The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26-27 October 2016, Oxford, UK. Vaccine, 35 (38). pp. 5081-5088. ISSN 0264-410X

Darton, T.C., Meiring, J.E. orcid.org/0000-0001-9183-5174, Tonks, S. et al. (18 more authors) (2017) The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. BMJ Open, 7 (6). e016283.

Tran Vu Thieu, N., Trinh Van, T., Tran Tuan, A. et al. (26 more authors) (2017) An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever. Journal of Infection, 75 (2). pp. 104-114.

Salerno-Goncalves, R., Luo, D., Fresnay, S. et al. (9 more authors) (2017) Challenge of humans with wild-type Salmonella enterica serovar Typhi elicits changes in the activation and homing characteristics of mucosal-associated invariant T cells. Frontiers in Immunology, 8. 398. ISSN 1664-3224

Fresnay, S., McArthur, M.A., Magder, L.S. et al. (8 more authors) (2017) Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model. Frontiers in Immunology, 8. 208.

Dobinson, H.C., Gibani, M.M., Jones, C. et al. (21 more authors) (2017) Evaluation of the clinical and microbiological response to Salmonella Paratyphi A infection in the first paratyphoid human challenge model. Clinical Infectious Diseases. ISSN 1058-4838

Darton, T.C. orcid.org/0000-0003-2209-9956, Zhou, L., Blohmke, C.J. et al. (4 more authors) (2017) Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia. Journal of Infection. ISSN 0163-4453

Darton, T.C. orcid.org/0000-0003-2209-9956, Jones, C., Blohmke, C.J. et al. (20 more authors) (2016) Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a. PLoS Negl Trop Dis, 10 (8). e0004926. ISSN 1935-2727

Toapanta, F.R., Bernal, P.J., Fresnay, S. et al. (9 more authors) (2016) Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease. PLoS Neglected Tropical Diseases, 10 (6). e0004766. ISSN 1935-2727

Blohmke, C.J., Darton, T.C. orcid.org/0000-0003-2209-9956, Jones, C. et al. (24 more authors) (2016) Interferon-driven alterations of the host's amino acid metabolism in the pathogenesis of typhoid fever. Journal of Experimental Medicine, 213 (6). pp. 1061-1077. ISSN 0022-1007

Zhou, L., Jones, C., Gibani, M.M. et al. (6 more authors) (2016) Development and Evaluation of a Blood Culture PCR Assay for Rapid Detection of Salmonella Paratyphi A in Clinical Samples. PLoS One, 11 (3). e0150576. ISSN 1932-6203

Fresnay, S., McArthur, M.A., Magder, L. et al. (8 more authors) (2016) Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans. Journal of Translational Medicine, 14. 62. ISSN 1479-5876

Gibani, M.M., Jin, C., Darton, T.C. et al. (1 more author) (2015) Control of Invasive Salmonella Disease in Africa: Is There a Role for Human Challenge Models? Clinical Infectious Diseases, 61 (4). S266 - S271. ISSN 1058-4838

Darton, T.C., Blohmke, C.J., Giannoulatou, E. et al. (7 more authors) (2015) Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans. PLoS Neglected Tropical Diseases, 9 (9). e0004029. - . ISSN 1935-2727

McCullagh, D., Dobinson, H.C., Darton, T. et al. (10 more authors) (2015) Understanding paratyphoid infection: study protocol for the development of a human model of Salmonella enterica serovar Paratyphi A challenge in healthy adult volunteers. BMJ Open, 5. e007481. - . ISSN 2044-6055

Toapanta, F.R., Bernal, P.J., Fresnay, S. et al. (9 more authors) (2015) Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease. PLoS Neglected Tropical Diseases, 9 (6). e0003837. ISSN 1935-2727

McArthur, M.A., Fresnay, S., Magder, L.S. et al. (9 more authors) (2015) Activation of salmonella typhi-specific regulatory T cells in typhoid disease in a wild-type s. Typhi challenge model. PLoS Pathogens, 11 (5). e1004914. ISSN 1553-7366

Jones, C., Darton, T.C. and Pollard, A.J. (2014) Why the development of effective typhoid control measures requires the use of human challenge studies. Frontiers in Microbiology, 5. 707. .

Reynolds, C.J., Jones, C., Blohmke, C.J. et al. (7 more authors) (2014) The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles. Immunology, 143 (3). 438 - 446.

Waddington, C.S., Darton, T.C., Angus, B. et al. (1 more author) (2014) Reply to Farmakiotis et al. Clinical Infectious Diseases, 59 (8). 1198 - 1199. ISSN 1058-4838

Waddington, C.S., Darton, T.C., Jones, C. et al. (16 more authors) (2014) An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution. Clinical Infectious Diseases, 58 (9). 1230 - 1240. ISSN 1058-4838