Items where authors include "Michel, M."

Article

Luttens, A. orcid.org/0000-0003-2915-7901, Vo, D.D., Scaletti, E.R. et al. (22 more authors) (2025) Virtual fragment screening for DNA repair inhibitors in vast chemical space. Nature Communications, 16. 1741. ISSN 2041-1723

Zhang, S.M., Paulin, C.B.J., Shu, H. et al. (24 more authors) (2024) Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel. iScience, 27 (2). 108907. ISSN 2589-0042

Jemth, A.-S., Scaletti, E.R., Homan, E. et al. (3 more authors) (2022) Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir. Journal of Biological Chemistry, 298 (8). 102169. ISSN 0021-9258

Benitéz‐Buelga, C., Helleday, T. and Michel, M. (2022) Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies. Clinical and Translational Medicine, 12 (8). e1035. ISSN 2001-1326

Patterson, N., Isakov, M., Booth, T. et al. (220 more authors) (2022) Large-scale migration into Britain during the Middle to Late Bronze Age. Nature. pp. 588-594. ISSN 0028-0836

Hanna, B.M.F., Michel, M., Helleday, T. orcid.org/0000-0002-7384-092X et al. (1 more author) (2021) NEIL1 and NEIL2 are recruited as potential backup for OGG1 upon OGG1 depletion or inhibition by TH5487. International Journal of Molecular Sciences, 22 (9). 4542. ISSN 1661-6596

Baquero, J.M., Benítez-Buelga, C., Rajagopal, V. et al. (13 more authors) (2021) Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects. Scientific Reports, 11 (1). 3490.

Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048

Michel, M., Homan, E.J., Wiita, E. et al. (6 more authors) (2020) In silico druggability assessment of the NUDIX hydrolase protein family as a workflow for target prioritization. Frontiers in Chemistry, 8. 443.

Michel, M., Visnes, T., Homan, E.J. et al. (12 more authors) (2019) Computational and experimental druggability assessment of human DNA glycosylases. ACS Omega, 4 (7). pp. 11642-11656. ISSN 2470-1343