Items where authors include "Leake, Mark Christian"

Article

Payne-Dwyer, Alex orcid.org/0000-0001-8802-352X, Kumar, Gaurav, Barrett, James et al. (6 more authors) (2024) Predicting Rubisco : Linker condensation from titration in the dilute phase. Physical Review Letters. ISSN 1079-7114 (In Press)

Shepherd, Jack, Guilbaud, Sébastien, Zhou, Zhaokun et al. (7 more authors) (2024) Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA. Nature Communications. 2748. ISSN 2041-1723

Wollman, Adam J.M., Syeda, Aisha Haneea orcid.org/0000-0003-3201-4135, Howard, Jamieson Anthony Leyland orcid.org/0000-0002-4694-5427 et al. (7 more authors) (2024) Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks. Journal of Molecular Biology. 168369. ISSN 0022-2836

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2023) Constructive Ignorance in the Physics of Life Network. Nature Physics. ISSN 1745-2473

Evans, Dominique, Khamas, Amanda B, Marcussen, Lisbeth et al. (7 more authors) (2023) GFP fusions of Sec-routed extracellular proteins in _Staphylococcus aureus_ reveals surface-associated coagulase in biofilms. Microbial Cell. ISSN 2311-2638 (In Press)

Fosado, Yair A G, Jamieson, Howard, Weir, Simon et al. (3 more authors) (2023) Fluidification of entanglements by a DNA bending protein. Physical Review Letters. 058203. ISSN 1079-7114

Jin, Xin, Zhang, Xiaowei, Ding, Xuejing et al. (7 more authors) (2023) Sensitive bacterial Vm sensors revealed the excitability of bacterial Vm and its role in antibiotic tolerance. Proceedings of the National Academy of Sciences of the United States of America. e2208348120. ISSN 1091-6490

Leake, Mark Christian orcid.org/0000-0002-1715-1249 and Quinn, Steven orcid.org/0000-0003-3442-4103 (2022) A Guide to Small Fluorescent Probes for Single-Molecule Biophysics. Chemical Physics Reviews. ISSN 2688-4070 (In Press)

Quinn, Steven orcid.org/0000-0003-3442-4103, Dresser, Lara, Graham, Sarah et al. (3 more authors) (2022) Crowding induced morphological changes in synthetic lipid vesicles determined using smFRET. Frontiers in Bioengineering and Biotechnology. (In Press)

Watson, George Daniel orcid.org/0000-0002-6524-0828, Chan, Elliot, Leake, Mark Christian orcid.org/0000-0002-1715-1249 et al. (1 more author) (2022) Structural interplay between DNA-shape protein recognition and supercoiling : the case of IHF. Computational and Structural Biotechnology Journal. pp. 5264-5274. ISSN 2001-0370

Lecinski, Sarah, Shepherd, Jack, Bunting, Kate et al. (4 more authors) (2022) Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes : in vitro and in vivo. Interface Focus. ISSN 2042-8898 (In Press)

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2022) Surviving Early Career Research and Beyond in Biophysics/Biological Physics : a concise user guide. Physical Biology. 050201. ISSN 1478-3975

Dresser, Lara, Graham, Sarah, Miller, Lisa Margaret orcid.org/0000-0003-3667-3840 et al. (5 more authors) (2022) Tween-20 Induces the Structural Remodeling of Single Lipid Vesicles. JOURNAL OF PHYSICAL CHEMISTRY LETTERS. 5341–5350. ISSN 1948-7185

Schnitzer, Barbara, Welkenhuysen, Niek, Leake, Mark Christian orcid.org/0000-0002-1715-1249 et al. (2 more authors) (2022) The effect of stress on biophysical characteristics of misfolded protein aggregates in living Saccharomyces cerevisiae cells. Experimental gerontology. 111755. ISSN 1873-6815

Reith, Patrick, Braam, Svenja, Welkenhuysen, Niek et al. (7 more authors) (2022) The effect of lithium on the budding yeast Saccharomyces cerevisiae upon stress adaptation. Microorganisms. ISSN 2076-2607

Yoshua, Samuel B, Watson, George Daniel orcid.org/0000-0002-6524-0828, Howard, Jamieson Anthony Leyland orcid.org/0000-0002-4694-5427 et al. (3 more authors) (2021) Integration host factor bends and bridges DNA in a multiplicity of binding modes with varying specificity. Nucleic Acids Research. 8684–8698. ISSN 0305-1048

Shepherd, Jack, Lecinski, Sarah, Wragg, Jasmine et al. (3 more authors) (2021) Molecular crowding in single eukaryotic cells : using cell environment biosensing and single-molecule optical microscopy to probe dependence on extracellular ionic strength, local glucose conditions, and sensor copy number. Methods. pp. 54-61. ISSN 1046-2023

Backer, Adam S, King, Graeme A, Biebricher, Andreas S et al. (6 more authors) (2021) Elucidating the Role of Topological Constraint on the Structure of Overstretched DNA using Fluorescence Polarization Microscopy. The Journal of Physical Chemistry. pp. 8351-8361.

Shepherd, Jack, Higgins, Edward, Wollman, Adam J.M. et al. (1 more author) (2021) PySTACHIO: Python Single-molecule TrAcking stoiCHiometry Intensity and simulatiOn, a flexible, extensible, beginner-friendly and optimized program for analysis of single-molecule microscopy. Computational and Structural Biotechnology Journal. pp. 4049-4058. ISSN 2001-0370

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2021) Correlative approaches in single-molecule biophysics: a review of the progress in methods and applications. Methods. pp. 1-4. ISSN 1046-2023

Saldivia, Manuel, Wollman, Adam J.M., Carnielli, Juliana B.T. et al. (5 more authors) (2021) A CLK1-KKT2 signaling pathway regulating kinetochore assembly in Trypanosoma brucei. MBio. e00687-21. ISSN 2150-7511

Shepherd, Jack, Payne-Dwyer, Alex orcid.org/0000-0001-8802-352X, Lee, Ji-Eun et al. (2 more authors) (2021) Combining single-molecule super-resolved localization microscopy with fluorescence polarization imaging to study cellular processes. Journal of Physics: Photonics. 034010. ISSN 2515-7647

Dienerowitz, Maria, Howard, Jamieson Anthony Leyland orcid.org/0000-0002-4694-5427, Quinn, Steven orcid.org/0000-0003-3442-4103 et al. (2 more authors) (2021) Single-molecule FRET dynamics of molecular motors in an ABEL Trap. Methods. pp. 96-106. ISSN 1046-2023

Laidlaw, Kamilla M.E., Bisinsk, Daniel D., Shashkova, Sviatlana et al. (4 more authors) (2021) A glucose starvation response governs endocytic trafficking and eisosomal retention of surface cargoes in budding yeast. Journal of Cell Science. 257733. ISSN 0021-9533

Shashkova, Sviatlana, Nyström, Thomas, Leake, Mark Christian orcid.org/0000-0002-1715-1249 et al. (1 more author) (2020) Correlative single-molecule fluorescence barcoding of gene regulation in Saccharomyces cerevisiae. Methods. ISSN 1046-2023

Juan-Colas, Jose orcid.org/0000-0002-1031-915X, Dresser, Lara, Morris, Katie et al. (7 more authors) (2020) The Mechanism of Vesicle Solubilization by the Detergent Sodium Dodecyl Sulfate. Langmuir. ISSN 1520-5827

Velasco Berrelleza, Victor, Burman, Matthew, Shepherd, Jack et al. (3 more authors) (2020) SerraNA : a program to determine nucleic acids elasticity from simulation data. Physical Chemistry Chemical Physics. pp. 19254-19266. ISSN 1463-9084

Coles, Mark Christopher orcid.org/0000-0001-8079-9358, O'Toole, Peter John orcid.org/0000-0001-5295-2001, Lacey, Charles John Nash orcid.org/0000-0001-9250-2638 et al. (28 more authors) (2020) B-cell Zone Reticular Cell Microenvironments Shape CXCL13 Gradient Formation. Nature Communications. 3677. ISSN 2041-1723

Wollman, Adam orcid.org/0000-0002-5501-8131, Muchováb, Katarina, Chromikováb, Zuzana et al. (3 more authors) (2020) Single-molecule optical microscopy of protein dynamics and computational analysis of images to determine cell structure development in differentiating Bacillus subtilis. Computational and Structural Biotechnology Journal. ISSN 2001-0370 (In Press)

Shashkova, Sviatlana, Andersson, Mikael, Hohmann, Stefan et al. (1 more author) (2020) Correlating single-molecule characteristics of the yeast aquaglyceroporin Fps1 with environmental perturbations directly in living cells. Methods. pp. 46-53. ISSN 1046-2023

Miller, Helen, Contera, Sonia, Wollman, Adam J.M. et al. (5 more authors) (2020) Biophysical characterization of DNA origami nanostructures reveals inaccessibility to intercalation binding sites. Nanotechnology. 235605. ISSN 0957-4484

Shepherd, Jack, Greenall, Robert James orcid.org/0000-0002-0922-1243, Probert, Matt orcid.org/0000-0002-1130-9316 et al. (2 more authors) (2020) The emergence of sequence-dependent structural motifs in stretched, torsionally 2 constrained DNA. Nucleic Acids Research. gkz1227. 1748–1763. ISSN 0305-1048

Syeda, Aisha Haneea orcid.org/0000-0003-3201-4135, Wollman, Adam orcid.org/0000-0002-5501-8131, Hargreaves, Alexander Leighton orcid.org/0000-0001-8802-352X et al. (4 more authors) (2019) Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome. Nucleic Acids Research. pp. 6287-6298. ISSN 0305-1048

Sun, Yaqi, Wollman, Adam orcid.org/0000-0002-5501-8131, Huang, Fang et al. (2 more authors) (2019) Single-Organelle Quantification Reveals Stoichiometric and Structural Variability of Carboxysomes Dependent on the Environment. The Plant Cell. pp. 1648-1664. ISSN 1532-298X

Wollman, Adam orcid.org/0000-0002-5501-8131, Hedlund, Erik Goran, Shashkova, Sviatlana et al. (1 more author) (2019) Towards mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells. Methods. ISSN 1046-2023

Haapasalo, Karita, Wollman, Adam orcid.org/0000-0002-5501-8131, de Haas, Carla et al. (3 more authors) (2019) Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration. The FASEB Journal. pp. 3807-3824. ISSN 1530-6860

Stracy, Mathew, Wollman, Adam orcid.org/0000-0002-5501-8131, Kaja, Elzbieta et al. (9 more authors) (2019) Single-molecule imaging of DNA gyrase activity in living Escherichia coli. Nucleic Acids Research. pp. 210-220. ISSN 0305-1048

Pu, Yingying, Li, Yingxing, Jin, Xin et al. (10 more authors) (2019) ATP-dependent dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic tolerance. Molecular Cell. 143-156.e4. ISSN 1097-2765

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2018) Transcription factors in eukaryotic cells can functionally regulate gene expression by acting in oligomeric assemblies formed from an intrinsically disordered protein phase transition enabled by molecular crowding. Transcription. pp. 298-306.

Leake, Mark Christian orcid.org/0000-0002-1715-1249 and Hoogenboom, Bart W. (2018) The case for biophysics super-groups in physics departments. Physical Biology. 060201. pp. 1-7. ISSN 1478-3975

Miller, Helen Louise, Cosgrove, Jason, Wollman, Adam orcid.org/0000-0002-5501-8131 et al. (5 more authors) (2018) High-speed single-molecule tracking of CXCL13 in the B-Follicle. Frontiers in immunology. 1073. p. 1073. ISSN 1664-3224

Foster, Simon, Lund, Victoria A, Wacnik, Katarzyna et al. (11 more authors) (2018) Molecular coordination of Staphylococcus aureus cell division. eLife. pp. 1-31. ISSN 2050-084X

Miller, Helen Louise, Zhou, Zhaokun, Shepherd, Jack William et al. (2 more authors) (2018) Single-molecule techniques in biophysics : a review of the progress in methods and applications. Reports on progress in physics. ISSN 0034-4885

Shashkova, Sviatlana and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2018) Systems biophysics : Single-molecule optical proteomics in single living cells. Current Opinion in Systems Biology. pp. 26-35. ISSN 2452-3100

Shashkova, Sviatlana, Wollman, Adam orcid.org/0000-0002-5501-8131, Hohmann, Stefan et al. (1 more author) (2018) Characterising maturation of GFP and mCherry of genomically integrated fusions in Saccharomyces cerevisiae. Bio-protocol. ISSN 2331-8325

Wollman, Adam orcid.org/0000-0002-5501-8131, Shashkova, Sviatlana, Hedlund, Erik Goran et al. (3 more authors) (2017) Transcription factor clusters regulate genes in eukaryotic cells. eLife. e27451. ISSN 2050-084X

Carrascosa, Jose L and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2017) Imaging the cell. Biophysical Reviews. ISSN 1867-2450

Shashkova, Sviatlana and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2017) Single-molecule fluorescence microscopy review : shedding new light on old problems. Bioscience Reports. ISSN 0144-8463

Shashkova, Sviatlana, Wollman, Adam orcid.org/0000-0002-5501-8131, Leake, Mark Christian orcid.org/0000-0002-1715-1249 et al. (1 more author) (2017) The yeast Mig1 transcriptional repressor is dephosphorylated by glucosedependent and independent mechanisms. FEMS microbiology letters. ISSN 0378-1097

Beattie, Thomas R., Kapadia, Nitin, Nicolas, Emilien et al. (4 more authors) (2017) Frequent exchange of the DNA polymerase during bacterial chromosome replication. eLife. e21763. ISSN 2050-084X

Dunn, Katherine Elizabeth orcid.org/0000-0002-5068-4354, Leake, Mark Christian orcid.org/0000-0002-1715-1249, Wollman, Adam orcid.org/0000-0002-5501-8131 et al. (3 more authors) (2017) An experimental study of the putative mechanism of a synthetic autonomous rotary DNA nanomotor. Royal Society Open Science. 160767. ISSN 2054-5703

Badrinarayanan, Anjana and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2016) Using Fluorescence Recovery After Photobleaching (FRAP) to study dynamics of the Structural Maintenance of Chromosome (SMC) complex in vivo. Methods in Molecular Biology. pp. 37-46. ISSN 1064-3745

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2016) The Biophysics of Infection. Advances in experimental medicine and biology. ISSN 0065-2598

Leake, Mark Christian orcid.org/0000-0002-1715-1249 and Zhou, Zhaokun (2016) Force spectroscopy in studying infection. Advances in experimental medicine and biology. pp. 307-327. ISSN 0065-2598

Miller, Helen Louise, Wollman, Adam orcid.org/0000-0002-5501-8131 and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2016) Designing a single-molecule biophysics tool for characterizing DNA damage for techniques that kill infectious pathogens through DNA damage effects. Advances in experimental medicine and biology. pp. 115-127. ISSN 0065-2598

Lenn, Tchern and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2016) Single-molecule studies of the dynamics and interactions of bacterial OXPHOS complexes. Biochimica et Biophysica Acta. Bioenergetics. pp. 224-231. ISSN 0005-2728

Wollman, Adam orcid.org/0000-0002-5501-8131 and Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2015) Millisecond single-molecule localization microscopy combined with convolution analysis and automated image segmentation to determine protein concentrations in complexly structured, functional cells, one cell at a time. FARADAY DISCUSSIONS. pp. 401-424. ISSN 1364-5498

Bryan, Samantha J, Burroughs, Nigel J, Shevela, Dmitriy et al. (11 more authors) (2014) Localisation and interactions of the Vipp1 protein in cyanobacteria. Molecular Microbiology. pp. 1179-1195. ISSN 0950-382X

Book Section

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2016) New advances in chromosome architecture. In: Leake, Mark C., (ed.) Chromosome Architecture. Methods in Molecular Biology . Springer .

Conference or Workshop Item

Leake, Mark Christian orcid.org/0000-0002-1715-1249 (2015) Innovative Science : The London Times, Letter to the Editor. In: UNSPECIFIED.