Items where authors include "Klenerman, D."

Article

Bruggeman, E. orcid.org/0000-0001-6100-1443, Zhang, O. orcid.org/0000-0001-7318-2130, Needham, L.-M. et al. (12 more authors) (2024) POLCAM: instant molecular orientation microscopy for the life sciences. Nature Methods, 21. pp. 1873-1883. ISSN 1548-7091

Xia, Z., Prescott, E.E., Urbanek, A. et al. (28 more authors) (2024) Co-aggregation with apolipoprotein E modulates the function of amyloid-β in Alzheimer's disease. Nature Communications, 15. 4695. ISSN 2041-1723

Daly, S. orcid.org/0000-0002-8559-3161, Ferreira Fernandes, J. orcid.org/0000-0002-8161-6709, Bruggeman, E. orcid.org/0000-0001-6100-1443 et al. (11 more authors) (2024) High-density volumetric super-resolution microscopy. Nature Communications, 15 (1). 1940. ISSN 2041-1723

Basu, S. orcid.org/0000-0002-1080-979X, Shukron, O., Hall, D. orcid.org/0000-0001-5284-609X et al. (33 more authors) (2023) Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD. Nature Structural & Molecular Biology, 30 (11). pp. 1628-1639. ISSN 1545-9993

Basu, S. orcid.org/0000-0002-1080-979X, Shukron, O., Hall, D. orcid.org/0000-0001-5284-609X et al. (33 more authors) (2023) Publisher Correction: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD. Nature Structural & Molecular Biology. ISSN 1545-9993

Emin, D., Zhang, Y.P., Lobanova, E. et al. (16 more authors) (2022) Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease. Nature Communications, 13 (1). 5512. ISSN 2041-1723

Choi, M.L. orcid.org/0000-0001-9414-8214, Chappard, A. orcid.org/0000-0002-9522-2575, Singh, B.P. et al. (27 more authors) (2022) Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity. Nature Neuroscience, 25. pp. 1134-1148. ISSN 1097-6256

Meng, J.X., Zhang, Y., Saman, D. et al. (15 more authors) (2022) Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses. Nature Communications, 13. 2692. ISSN 2041-1723

Angelova, P.R., Choi, M.L., Berezhnov, A.V. et al. (16 more authors) (2020) Alpha synuclein aggregation drives ferroptosis : an interplay of iron, calcium and lipid peroxidation. Cell Death & Differentiation, 27 (10). pp. 2781-2796. ISSN 1350-9047

Flagmeier, P., De, S. orcid.org/0000-0003-1675-0773, Michaels, T.C.T. et al. (8 more authors) (2020) Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation. Nature Structural & Molecular Biology, 27 (10). pp. 886-891. ISSN 1545-9993

Whiten, D.R., Brownjohn, P.W., Moore, S. et al. (6 more authors) (2020) TNF induces increased production of extracellular amyloid-β- and α-synuclein-containing aggregates by human Alzheimer’s disease neurons. Brain Communications, 2 (2). fcaa146. ISSN 2632-1297

Sanderson, J.B., De, S. orcid.org/0000-0003-1675-0773, Jiang, H. et al. (14 more authors) (2020) Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with lewy bodies. Brain Communications, 2 (1).

De, S. orcid.org/0000-0003-1675-0773 and Klenerman, D. (2019) Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1867 (10). pp. 870-878. ISSN 1570-9639

De, S. orcid.org/0000-0003-1675-0773, Whiten, D.R., Ruggeri, F.S. et al. (14 more authors) (2019) Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression. Acta Neuropathologica Communications, 7 (1). 120. ISSN 2051-5960

Sang, J.C., Lee, J.-E., Dear, A.J. et al. (6 more authors) (2019) Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species. Chemical Science, 10 (17). pp. 4588-4597. ISSN 2041-6520

De, S. orcid.org/0000-0003-1675-0773, Wirthensohn, D.C., Flagmeier, P. et al. (14 more authors) (2019) Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms. Nature Communications, 10 (1). 1541. ISSN 2041-1723

Lee, J.-E., Sang, J.C., Rodrigues, M. et al. (9 more authors) (2018) Mapping surface hydrophobicity of α-synuclein oligomers at the nanoscale. Nano Letters, 18 (12). pp. 7494-7501. ISSN 1530-6984

Iljina, M., Dear, A.J., Garcia, G.A. et al. (9 more authors) (2018) Quantifying co-oligomer formation by α-synuclein. ACS Nano, 12 (11). pp. 10855-10866. ISSN 1936-0851

Whiten, D.R., Zuo, Y., Calo, L. et al. (14 more authors) (2018) Nanoscopic characterisation of individual endogenous protein aggregates in human neuronal cells. ChemBioChem, 19 (19). pp. 2033-2038. ISSN 1439-4227

Whiten, D.R., Cox, D., Horrocks, M.H. et al. (9 more authors) (2018) Single-molecule characterization of the interactions between extracellular chaperones and toxic α-synuclein oligomers. Cell Reports, 23 (12). pp. 3492-3500. ISSN 2211-1247

Varela, J.A., Rodrigues, M., De, S. et al. (5 more authors) (2018) Optical structural analysis of individual α-synuclein oligomers. Angewandte Chemie International Edition, 57 (18). pp. 4886-4890. ISSN 1433-7851

Kundel, F., De, S. orcid.org/0000-0003-1675-0773, Flagmeier, P. et al. (6 more authors) (2018) Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity. ACS Chemical Biology, 13 (3). pp. 636-646. ISSN 1554-8929

Drews, A., De, S. orcid.org/0000-0003-1675-0773, Flagmeier, P. et al. (14 more authors) (2017) Inhibiting the Ca 2+ influx induced by human CSF. Cell Reports, 21 (11). pp. 3310-3316. ISSN 2211-1247

Flagmeier, P., De, S. orcid.org/0000-0003-1675-0773, Wirthensohn, D.C. et al. (7 more authors) (2017) Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates. Angewandte Chemie International Edition, 56 (27). pp. 7750-7754. ISSN 1433-7851