Items where authors include "Cubbon, RM"
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Brown, OI, Drozd, M, McGowan, H et al. (13 more authors) (2023) Relationship among diabetes, obesity and cardiovascular disease phenotypes: a UK Biobank cohort study. Diabetes Care. dc230294. ISSN 0149-5992
Endesh, N, Chuntharpursat-BON, E, Revill, C et al. (11 more authors) (2023) Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver International. ISSN 1478-3223
Straw, S orcid.org/0000-0002-2942-4574, Cole, CA, McGinlay, M et al. (9 more authors) (2023) Guideline-directed medical therapy is similarly effective in heart failure with mildly reduced ejection fraction. Clinical Research in Cardiology, 112 (1). pp. 111-122. ISSN 1861-0684
Imrie, H, Viswambharan, H orcid.org/0000-0002-7616-5026, Haywood, NJ et al. (14 more authors) (2022) Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity. Adipocyte, 11 (1). pp. 366-378. ISSN 2162-3945
Gierula, J orcid.org/0000-0001-9588-191X, Cole, CA, Drozd, M orcid.org/0000-0003-0255-4624 et al. (18 more authors) (2022) Atrial fibrillation and risk of progressive heart failure in patients with preserved ejection fraction heart failure. ESC Heart Failure, 9 (5). pp. 3254-3263. ISSN 2055-5822
Jex, N, Chowdhary, A, Thirunavukarasu, S et al. (13 more authors) (2022) Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy. Diabetes Care, 45 (8). pp. 1852-1862. ISSN 0149-5992
Drozd, M orcid.org/0000-0003-0255-4624, Pujades-Rodriguez, M, Morgan, AW et al. (4 more authors) (2022) Systemic inflammation is associated with future risk of fatal infection: an observational cohort study. The Journal of Infectious Diseases. ISSN 0022-1899
Malik, A, Garland, E, Drozd, M orcid.org/0000-0003-0255-4624 et al. (11 more authors) (2022) Diabetes mellitus and the causes of hospitalisation in people with heart failure. Diabetes and Vascular Disease Research, 19 (1). pp. 1-7. ISSN 1479-1641
Paton, MF orcid.org/0000-0001-8517-4621, Gierula, J orcid.org/0000-0001-9588-191X, Lowry, JE et al. (9 more authors) (2021) Personalised reprogramming to prevent progressive pacemaker-related left ventricular dysfunction: A phase II randomised, controlled clinical trial. PLoS ONE, 16 (12). e0259450. ISSN 1932-6203
Drozd, M, Pujades-Rodriguez, M, Sun, F et al. (5 more authors) (2021) Causes of death in people with cardiovascular disease: a UK Biobank cohort study. Journal of the American Heart Association, 10 (22). e023188. ISSN 2047-9980
Straw, S orcid.org/0000-0002-2942-4574, McGinlay, M, Gierula, J et al. (9 more authors) (2021) Impact of QRS duration on left ventricular remodelling and survival in patients with heart failure. Journal of Cardiovascular Medicine, 22 (11). pp. 848-856. ISSN 1558-2027
Thirunavukarasu, S, Jex, N, Chowdhary, A et al. (13 more authors) (2021) Empagliflozin Treatment is Associated With Improvements in Cardiac Energetics and Function and Reductions in Myocardial Cellular Volume in Patients With Type 2 Diabetes. Diabetes. ISSN 0012-1797
Warmke, N, Platt, F, Bruns, AF et al. (11 more authors) (2021) Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling. Endocrinology. ISSN 0013-7227
Viswambharan, H orcid.org/0000-0002-7616-5026, Yuldasheva, NY, Imrie, H et al. (22 more authors) (2021) Novel Paracrine Action of Endothelium enhances Glucose Uptake in Muscle and Fat. Circulation Research. ISSN 0009-7330
Walker, AMN orcid.org/0000-0003-0380-7283, Warmke, N, Mercer, B et al. (13 more authors) (2021) Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis. Endocrinology, 162 (8). bqab104. ISSN 0013-7227
Drozd, M orcid.org/0000-0003-0255-4624, Pujades-Rodriguez, M, Lillie, P et al. (5 more authors) (2021) Non-communicable disease, sociodemographic factors, and risk of death from infection: a UK Biobank observational cohort study infection death: a UK Biobank observational cohort study. The Lancet Infectious Diseases, 21 (8). pp. 1184-1191. ISSN 1473-3099
McGinlay, M, Straw, S orcid.org/0000-0002-2942-4574, Byrom-Goulthorp, R et al. (5 more authors) (2021) Suboptimal Dosing of β-Blockers in Chronic Heart Failure: A Missed Opportunity? Journal of Cardiovascular Nursing. ISSN 0889-4655
Duval, C orcid.org/0000-0002-4870-6542, Baranauskas, A, Feller, T et al. (14 more authors) (2021) Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences, 118 (27). e2103226118. ISSN 0027-8424
Haywood, NJ orcid.org/0000-0002-8762-7257, Luk, C orcid.org/0000-0002-6828-5423, Bridge, KI et al. (20 more authors) (2021) Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity. EMBO Reports, 22 (5). e50767. ISSN 1469-221X
Kearney, J, Drozd, M orcid.org/0000-0003-0255-4624, Walker, AMN et al. (9 more authors) (2021) Diabetes, gender and deterioration in estimated glomerular filtration rate in patients with chronic heart failure: ten-year prospective cohort study. Diabetes and Vascular Disease Research, 18 (1). pp. 1-7. ISSN 1479-1641
Straw, S orcid.org/0000-0002-2942-4574, McGinlay, M, Drozd, M orcid.org/0000-0003-0255-4624 et al. (13 more authors) (2021) Advanced care planning during the COVID-19 pandemic: ceiling of care decisions and their implications for observational data. BMC Palliative Care, 20 (1). 10. ISSN 1472-684X
Pujades-Roderiguez, M, Morgan, AW orcid.org/0000-0003-1109-624X, Cubbon, RM orcid.org/0000-0001-7844-3600 et al. (1 more author) (2020) Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study. PLoS Medicine, 17 (12). e1003432. ISSN 1549-1277
Straw, S orcid.org/0000-0002-2942-4574, McGinlay, M, Relton, SD orcid.org/0000-0003-0634-4587 et al. (9 more authors) (2020) Effect of disease-modifying agents and their association with mortality in multi-morbid patients with heart failure with reduced ejection fraction. ESC Heart Failure, 7 (6). pp. 3859-3870. ISSN 2055-5822
Drozd, M orcid.org/0000-0003-0255-4624, Relton, SD orcid.org/0000-0003-0634-4587, Walker, AMN et al. (13 more authors) (2020) Association of heart failure and its comorbidities with loss of life expectancy. Heart. ISSN 1355-6037
Koshy, AO, Gallivan, ER, McGinlay, M et al. (7 more authors) (2020) Prioritizing symptom management in the treatment of chronic heart failure. ESC Heart Failure, 7 (5). pp. 2193-2207. ISSN 2055-5822
Caspi, T, Straw, S orcid.org/0000-0002-2942-4574, Cheng, C orcid.org/0000-0002-2873-0828 et al. (14 more authors) (2020) Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy. Journal of the American Heart Association. ISSN 2047-9980
Gierula, J orcid.org/0000-0001-9588-191X, Lowry, JE orcid.org/0000-0002-9793-1519, Paton, MF orcid.org/0000-0001-8517-4621 et al. (12 more authors) (2020) Personalized Rate-Response Programming Improves Exercise Tolerance After 6 Months in People With Cardiac Implantable Electronic Devices and Heart Failure: A Phase II Study. Circulation, 141 (21). pp. 1693-1703. ISSN 0009-7322
Maqbool, A, Watt, N, Haywood, N et al. (17 more authors) (2020) Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance related vascular damage. American Journal of Physiology: Cell Physiology. ISSN 0363-6143
Drozd, M orcid.org/0000-0003-0255-4624, Garland, E, Walker, AMN et al. (10 more authors) (2020) Infection-Related Hospitalization in Heart Failure With Reduced Ejection Fraction: A Prospective Observational Cohort Study. Circulation: Heart Failure, 13 (5). e006746. ISSN 1941-3289
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Espino-Gonzalez, E et al. (10 more authors) (2020) Chronic heart failure with diabetes mellitus is characterized by a severe skeletal muscle pathology. Journal of Cachexia, Sarcopenia and Muscle, 11 (2). pp. 394-404. ISSN 2190-5991
McNally, BD, Moran, A, Watt, NT et al. (8 more authors) (2020) Inorganic Nitrate Promotes Glucose Uptake and Oxidative Catabolism in White Adipose Tissue through the XOR Catalyzed Nitric Oxide Pathway. Diabetes. db190892. ISSN 0012-1797
Garnham, JO, Roberts, LD orcid.org/0000-0002-1455-5248, Caspi, T et al. (10 more authors) (2020) Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure. Journal of Cachexia, Sarcopenia and Muscle, 11 (1). pp. 79-88. ISSN 2190-5991
Haywood, NJ orcid.org/0000-0002-8762-7257, Slater, TA orcid.org/0000-0001-9213-5559, Drozd, M orcid.org/0000-0003-0255-4624 et al. (12 more authors) (2020) IGFBP-1 in Cardiometabolic Pathophysiology—Insights From Loss-of-Function and Gain-of-Function Studies in Male Mice. Journal of the Endocrine Society, 4 (1). bvz006. ISSN 2472-1972
Cubbon, RM orcid.org/0000-0001-7844-3600, Lowry, JE, Drozd, M orcid.org/0000-0003-0255-4624 et al. (8 more authors) (2019) Vitamin D deficiency is an independent predictor of mortality in patients with chronic heart failure. European Journal of Nutrition, 58 (6). pp. 2535-2543. ISSN 1436-6207
Paton, MF orcid.org/0000-0001-8517-4621, Gierula, J orcid.org/0000-0001-9588-191X, Jamil, HA et al. (9 more authors) (2019) Optimising pacemaker therapy and medical therapy in pacemaker patients for heart failure: protocol for the OPT-PACE randomised controlled trial. BMJ open, 9 (7). e028613. ISSN 2044-6055
Gierula, J orcid.org/0000-0001-9588-191X, Cubbon, RM orcid.org/0000-0001-7844-3600, Paton, MF et al. (15 more authors) (2019) Prospective evaluation and long term follow up of patients referred to secondary care based upon natriuretic peptide levels in primary care. European Heart Journal - Quality of Care and Clinical Outcomes, 5 (3). pp. 218-224. ISSN 2058-5225
Jamil, HA, Mohammed, SA, Gierula, J orcid.org/0000-0001-9588-191X et al. (5 more authors) (2019) Prognostic Significance of Incidental Nonsustained Ventricular Tachycardia Detected on Pacemaker Interrogation. American Journal of Cardiology, 123 (3). pp. 409-413. ISSN 0002-9149
Mercer, BN, Koshy, A, Drozd, M orcid.org/0000-0003-0255-4624 et al. (9 more authors) (2018) Ischemic Heart Disease Modifies the Association of Atrial Fibrillation With Mortality in Heart Failure With Reduced Ejection Fraction. Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 7 (20). e009770. ISSN 2047-9980
Walker, AMN, Drozd, M orcid.org/0000-0003-0255-4624, Hall, M et al. (10 more authors) (2018) Prevalence and Predictors of Sepsis Death in Patients With Chronic Heart Failure and Reduced Left Ventricular Ejection Fraction. Journal of the American Heart Association, 7 (20). e009684. ISSN 2047-9980
Sengupta, A, Patel, PA, Yuldasheva, NY orcid.org/0000-0001-6213-6358 et al. (13 more authors) (2018) Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice. Endocrinology, 159 (8). pp. 2917-2925. ISSN 0013-7227
Witte, KK orcid.org/0000-0002-7146-7105, Patel, PA, Walker, AMN et al. (8 more authors) (2018) Socioeconomic deprivation and mode-specific outcomes in patients with chronic heart failure. Heart, 104 (12). pp. 993-998. ISSN 1355-6037
Pedicini, L, Miteva, KT, Hawley, V et al. (7 more authors) (2018) Homotypic endothelial nanotubes induced by wheat germ agglutinin and thrombin. Scientific Reports, 8. 7569. ISSN 2045-2322
Aziz, A, Haywood, NJ orcid.org/0000-0002-8762-7257, Cordell, PA et al. (11 more authors) (2018) Insulinlike Growth Factor-Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance. Endocrinology, 159 (2). pp. 696-709. ISSN 0013-7227
Gierula, J orcid.org/0000-0001-9588-191X, Paton, MF, Lowry, JE et al. (8 more authors) (2018) Rate-Response Programming Tailored to the Force-Frequency Relationship Improves Exercise Tolerance in Chronic Heart Failure. JACC: Heart Failure, 6 (2). pp. 105-113. ISSN 2213-1779
Witte, KK orcid.org/0000-0002-7146-7105, Drozd, M orcid.org/0000-0003-0255-4624, Walker, AMN et al. (9 more authors) (2018) Mortality Reduction Associated With β-Adrenoceptor Inhibition in Chronic Heart Failure Is Greater in Patients With Diabetes. Diabetes Care, 41 (1). pp. 136-142. ISSN 0149-5992
Watt, NT, Gage, MC, Patel, PA et al. (15 more authors) (2017) Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance. Diabetes, 66 (11). pp. 2808-2821. ISSN 0012-1797
Nelson, CP, Goel, A, Butterworth, A et al. (62 more authors) (2017) Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nature Genetics, 49 (9). pp. 1385-1391. ISSN 1061-4036
Rode, B, Shi, J, Endesh, N et al. (22 more authors) (2017) Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance. Nature Communications, 8. 350. ISSN 2041-1723
Viswambharan, VH orcid.org/0000-0002-7616-5026, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Sengupta, A et al. (18 more authors) (2017) Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop. Circulation Research, 120 (5). pp. 784-798. ISSN 0009-7330
Haywood, NJ orcid.org/0000-0002-8762-7257, Cordell, PA, Tang, KY et al. (8 more authors) (2017) Insulin-Like Growth Factor Binding Protein 1 Could Improve Glucose Regulation and Insulin Sensitivity Through Its RGD Domain. Diabetes, 66 (2). pp. 287-299. ISSN 0012-1797
Warmke, N, Griffin, KJ and Cubbon, RM orcid.org/0000-0001-7844-3600 (2016) Pericytes in diabetes-associated vascular disease. Journal of Diabetes and its Complications, 30 (8). pp. 1643-1650. ISSN 1056-8727
Walker, AMN, Patel, PA, Rajwani, A et al. (7 more authors) (2016) Diabetes mellitus is associated with adverse structural and functional cardiac remodelling in chronic heart failure with reduced ejection fraction. Diabetes and Vascular Disease Research, 13 (5). pp. 331-340. ISSN 1479-1641
Witte, KK orcid.org/0000-0002-7146-7105, Byrom, R, Gierula, J et al. (14 more authors) (2016) Effects of Vitamin D on Cardiac Function in Patients With Chronic HF: The VINDICATE Study. Journal of the American College of Cardiology, 67 (22). pp. 2593-2603. ISSN 0735-1097
Cubbon, RM, Witte, KK, Kearney, LC et al. (11 more authors) (2016) Performance of 2014 NICE defibrillator implantation guidelines in heart failure risk stratification. Heart, 102 (10). pp. 735-740. ISSN 1355-6037
Jamil, HA, Gierula, J, Paton, MF et al. (6 more authors) (2016) Chronotropic incompetence does not limit exercise capacity in chronic heart failure. Journal of the American College of Cardiology, 67 (16). pp. 1885-1896. ISSN 0735-1097
Cubbon, RM, Ruff, N, Groves, D et al. (15 more authors) (2016) Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure. Heart, 102 (3). pp. 223-229. ISSN 1355-6037
Gierula, J, Cubbon, RM, Jamil, HA et al. (5 more authors) (2015) Patients with long-term permanent pacemakers have a high prevalence of left ventricular dysfunction. Journal of Cardiovascular Medicine, 16 (11). 743 - 750. ISSN 1558-2027
Cubbon, RM, Thomas, CH, Drozd, M et al. (6 more authors) (2015) Calcium, phosphate and calcium phosphate product are markers of outcome in patients with chronic heart failure. Journal of Nephrology, 28 (2). dx.doi.org/10.1007/s40620-014-0075-y. pp. 209-215. ISSN 1121-8428
Li, J, Hou, B, Tumova, S orcid.org/0000-0003-2044-4998 et al. (25 more authors) (2014) Piezo1 integration of vascular architecture with physiological force. Nature, 515. pp. 279-282. ISSN 0028-0836
Cubbon, RM orcid.org/0000-0001-7844-3600, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Viswambharan, H orcid.org/0000-0002-7616-5026 et al. (20 more authors) (2014) Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential. Stem Cells, 32 (10). pp. 2714-2723. ISSN 1066-5099
Cubbon, RM, Woolston, A, Adams, B et al. (11 more authors) (2014) Prospective development and validation of a model to predict heart failure hospitalisation. Heart, 100 (12). 923 - 929. ISSN 1355-6037
Gierula, J, Cubbon, RM, Jamil, HA et al. (7 more authors) (2013) Cardiac resynchronization therapy in pacemaker-dependent patients with left ventricular dysfunction. Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 15 (11). 1609 - 1614. ISSN 1099-5129
Sukumar, P orcid.org/0000-0002-3294-989X, Viswambharan, H orcid.org/0000-0002-7616-5026, Imrie, H orcid.org/0000-0002-1940-6604 et al. (14 more authors) (2013) Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction. Diabetes, 62 (6). pp. 2130-2134. ISSN 0012-1797
Rakobowchuk, M, Harris, E, Taylor, A et al. (2 more authors) (2013) Moderate and heavy metabolic stress interval training improve arterial stiffness and heart rate dynamics in humans. European Journal of Applied Physiology, 113 (4). 839 - 849. ISSN 1439-6319
Imrie, H orcid.org/0000-0002-1940-6604, Viswambharan, H orcid.org/0000-0002-7616-5026, Sukumar, P et al. (16 more authors) (2012) Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice. Diabetes, 61 (9). pp. 2359-2368. ISSN 0012-1797
Rakobowchuk, M, Harris, E, Taylor, A et al. (4 more authors) (2012) Heavy and moderate interval exercise training alters low-flow-mediated constriction but does not increase circulating progenitor cells in healthy humans. Experimental Physiology, 97 (3). pp. 375-385. ISSN 0958-0670
Abbas, A, Imrie, H orcid.org/0000-0002-1940-6604, Viswambharan, H orcid.org/0000-0002-7616-5026 et al. (14 more authors) (2011) The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium. Diabetes, 60 (8). pp. 2169-2178. ISSN 0012-1797
Kahn, MB, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Cubbon, RM orcid.org/0000-0001-7844-3600 et al. (12 more authors) (2011) Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration. Diabetes, 60 (4). pp. 1295-1303. ISSN 0012-1797
Cubbon, RM orcid.org/0000-0001-7844-3600, Abbas, A, Wheatcroft, SB orcid.org/0000-0002-6741-9012 et al. (7 more authors) (2008) Diabetes Mellitus and Mortality after Acute Coronary Syndrome as a First or Recurrent Cardiovascular Event. PLoS One, 3 (10). e3483. ISSN 1932-6203
Book Section
Clavane, EM, Taylor, HA, Cubbon, RM orcid.org/0000-0001-7844-3600 et al. (1 more author) (2022) Endothelial Cell Fibrin Gel Angiogenesis Bead Assay. In: Benest, AV, (ed.) Angiogenesis: Methods and Protocols. Methods in Molecular Biology, 2441 . Springer , New York, USA , pp. 321-327. ISBN 978-1-0716-2058-8
Proceedings Paper
Drozd, M orcid.org/0000-0003-0255-4624, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Maqbool, A et al. (9 more authors) (2018) Increasing endothelial insulin-like growth factor-1 receptor expression reduces circulating leukocytes and protects against atherosclerosis. In: Cardiovascular Research. Annual meeting of the British Atherosclerosis Society, 06-07 Sep 2018, Cambridge. Oxford University Press , S3-S3.
Warmke, N orcid.org/0000-0001-8037-2186, Griffin, KJ, Slater, CI et al. (3 more authors) (2017) Reduced pericyte insulin signalling causes abnormal developmental angiogenesis. In: Heart. BCS Annual Conference - Cardiology at the Extremes, 05-07 Jun 2017, Manchester, UK. BMJ Publishing Group , A127-A128.
Mercer, BN, Walker, AMN, Warmke, N orcid.org/0000-0001-8037-2186 et al. (10 more authors) (2016) Systemic insulin resistance without dysglycaemia impairs angiogenesis. In: Heart. BSCR Autumn 2016 - Cardiovascular Disease and Diabetes, 05-06 Sep 2016, Leeds, UK. BMJ Publishing Group , A1-A1.
Walker, AMN, Yuldasheva, N orcid.org/0000-0001-6213-6358, Sengupta, A et al. (14 more authors) (2016) Vascular repair and regeneration are improved with reduced expression of the insulin-like growth factor-1 receptor in whole body insulin resistance. In: Heart. BSCR Autumn 2016, 05-06 Sep 2016, Leeds, UK. BMJ Publishing Group , A7-A7.