Items where authors include "Brockhurst, M.A."

Article

Wright, R.C.T., Wood, A.J., Bottery, M.J. et al. (5 more authors) (2024) A chromosomal mutation is superior to a plasmid-encoded mutation for plasmid fitness cost compensation. PLOS Biology, 22 (12). e3002926. ISSN 1544-9173

Buddle, J.E., Thompson, L.M., Williams, A.S. et al. (6 more authors) (2024) Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits. PLOS Biology, 22 (8). e3002741. ISSN 1545-7885

Brockhurst, M.A. orcid.org/0000-0003-0362-820X, Cameron, D.D. and Beckerman, A.P. orcid.org/0000-0002-4797-9143 (2024) Fitness trade-offs and the origins of endosymbiosis. PLOS Biology, 22 (4). e3002580. ISSN 1545-7885

Bird, S.M., Ford, S., Thompson, C.M.A. et al. (6 more authors) (2023) Compensatory mutations reducing the fitness cost of plasmid carriage occur in plant rhizosphere communities. FEMS Microbiology Ecology, 99 (4). fiad027. ISSN 0168-6496

Carrilero, L., Dunn, S.J., Moran, R.A. et al. (2 more authors) (2023) Evolutionary responses to acquiring a multidrug resistance plasmid are dominated by metabolic functions across diverse Escherichia coli lineages. mSystems, 8 (1). e0071322. ISSN 2379-5077

Thompson, C.M.A. orcid.org/0000-0002-0069-2727, Hall, J.P.J., Chandra, G. et al. (11 more authors) (2023) Plasmids manipulate bacterial behaviour through translational regulatory crosstalk. PLOS Biology, 21 (2). e3001988. ISSN 1544-9173

Hull, R.C., Wright, R.C.T., Sayers, J.R. orcid.org/0000-0002-5082-1443 et al. (5 more authors) (2022) Antibiotics limit adaptation of drug-resistant Staphylococcus aureus to hypoxia. Antimicrobial Agents and Chemotherapy, 66 (12). e00926-22. ISSN 0066-4804

Coyte, K.Z., Stevenson, C., Knight, C.G. et al. (3 more authors) (2022) Horizontal gene transfer and ecological interactions jointly control microbiome stability. PLoS Biology, 20 (11). e3001847-e3001847. ISSN 1544-9173

Brockhurst, M.A. and Harrison, E. orcid.org/0000-0002-2050-4631 (2022) Ecological and evolutionary solutions to the plasmid paradox. Trends in Microbiology, 30 (6). pp. 534-543. ISSN 0966-842X

White, N.J. orcid.org/0000-0002-0898-760X, Beckerman, A.P. orcid.org/0000-0002-4797-9143, Snook, R.R. et al. (3 more authors) (2022) Experimental evolution of local adaptation under unidimensional and multidimensional selection. Current Biology, 32 (6). 1310-1318.e4. ISSN 0960-9822

Billane, K., Harrison, E. orcid.org/0000-0002-2050-4631, Cameron, D. et al. (1 more author) (2022) Why do plasmids manipulate the expression of bacterial phenotypes? Philosophical Transactions of the Royal Society B: Biological Sciences, 377 (1842). ISSN 0962-8436

Hall, J.P.J., Wright, R.C.T., Harrison, E. orcid.org/0000-0002-2050-4631 et al. (4 more authors) (2021) Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation. PLoS Biology, 19 (10). e3001225. ISSN 1544-9173

Sørensen, M.E.S., Wood, A.J., Cameron, D.D. orcid.org/0000-0002-5439-6544 et al. (1 more author) (2021) Rapid compensatory evolution can rescue low fitness symbioses following partner switching. Current Biology, 31 (17). 3721-3728.e4. ISSN 0960-9822

Kottara, A., Carrilero, L., Harrison, E. orcid.org/0000-0002-2050-4631 et al. (2 more authors) (2021) The dilution effect limits plasmid horizontal transmission in multispecies bacterial communities. Microbiology, 167 (9). 001086. ISSN 1350-0872

Carrilero, L., Kottara, A., Guymer, D. et al. (3 more authors) (2021) Positive selection inhibits plasmid coexistence in bacterial genomes. mBio, 12 (3). e00558-21. ISSN 2161-2129

Evans, R., Beckerman, A.P. orcid.org/0000-0002-4797-9143, Wright, R.C.T. et al. (3 more authors) (2020) Eco-evolutionary dynamics set the tempo and trajectory of metabolic evolution in multispecies communities. Current Biology, 30 (24). 4984-4988.e4. ISSN 0960-9822

Hall, J.P.J., Harrison, E. orcid.org/0000-0002-2050-4631, Pärnänen, K. et al. (2 more authors) (2020) The impact of mercury selection and conjugative genetic elements on community structure and resistance gene transfer. Frontiers in Microbiology, 11. 01846.

Frost, C.L., Siozios, S., Nadal-Jimenez, P. et al. (4 more authors) (2020) The hypercomplex genome of an insect reproductive parasite highlights the importance of lateral gene transfer in symbiont biology. mBio, 11 (2). e02590-19. ISSN 2150-7511

Sørensen, M.E.S., Wood, A.J., Minter, E.J.A. et al. (3 more authors) (2020) Comparison of independent evolutionary origins reveals both convergence and divergence in the metabolic mechanisms of symbiosis. Current Biology, 30 (2). 328-334.e4. ISSN 0960-9822

Brockhurst, M.A., Harrison, E., Hall, J.P.J. et al. (3 more authors) (2019) The ecology and evolution of pangenomes. Current Biology, 29 (20). R1094-R1103. ISSN 0960-9822

Hall, J.P.J., Wright, R.C.T., Guymer, D. et al. (2 more authors) (2019) Extremely fast amelioration of plasmid fitness costs by multiple functionally diverse pathways. Microbiology, 166 (1). pp. 56-62. ISSN 1350-0872

O'Brien, S., Kümmerli, R., Paterson, S. et al. (2 more authors) (2019) Transposable temperate phages promote the evolution of divergent social strategies in Pseudomonas aeruginosa populations. Proceedings of the Royal Society B: Biological Sciences, 286 (1912). ISSN 0962-8452

Wright, R.C.T., Friman, V.P., Smith, M.C.M. et al. (1 more author) (2019) Resistance evolution against phage combinations depends on the timing and order of exposure. mBio, 10 (5). 01652-19.

Sørensen, M.E.S., Lowe, C.D., Minter, E.J.A. et al. (3 more authors) (2019) The role of exploitation in the establishment of mutualistic microbial symbioses. FEMS Microbiology Letters, 366 (12). ISSN 0378-1097

Tariq, M.A., Everest, F.L.C., Cowley, L.A. et al. (13 more authors) (2019) Temperate bacteriophages from chronic Pseudomonas aeruginosa lung infections show disease-specific changes in host range and modulate antimicrobial susceptibility. mSystems, 4 (4). ISSN 2379-5077

Brockhurst, M.A., Harrison, F., Veening, J.-W. et al. (4 more authors) (2019) Assessing evolutionary risks of resistance for new antimicrobial therapies. Nature Ecology and Evolution, 3 (4). pp. 515-517. ISSN 2397-334X

Bottery, M., Wood, J. and Brockhurst, M.A. (2019) Temporal dynamics of bacteria-plasmid coevolution under antibiotic selection. ISME Journal, 13 (2). pp. 559-562. ISSN 1751-7362

Zwanzig, M., Harrison, E., Brockhurst, M.A. et al. (3 more authors) (2019) Mobile compensatory mutations promote plasmid survival. mSystems, 4 (1). e00186-18. ISSN 2379-5077

Hall, J., Harrison, E.A. and Brockhurst, M.A. (2018) Competitive species interactions constrain abiotic adaptation in a bacterial soil community. Evolution Letters, 2 (6). pp. 580-589. ISSN 2056-3744

Wright, R.C.T., Friman, V.-P., Smith, M.C.M. et al. (1 more author) (2018) Cross-resistance is modular in bacteria-phage interactions. PLoS Biology, 16 (10). e2006057. ISSN 1545-7885

Minter, E.J.A., Lowe, C.D., Sorensen, M.E.S. et al. (3 more authors) (2018) Variation and asymmetry in host-symbiont dependence in a microbial symbiosis. BMC Evolutionary Biology, 18. 108.

Williams, D., Fothergill, J.L., Evans, B. et al. (6 more authors) (2018) Transmission and lineage displacement drive rapid population genomic flux in cystic fibrosis airway infections of a Pseudomonas aeruginosa epidemic strain. Microbial Genomics, 4 (3).

Stevenson, C., Hall, J., Brockhurst, M.A. et al. (1 more author) (2018) Plasmid stability is enhanced by higher-frequency pulses of positive selection. Proceedings of the Royal Society B: Biological Sciences, 285 (1870). ISSN 0962-8452

Kottara, A., Hall, J.P.J., Harrison, E. et al. (1 more author) (2018) Variable plasmid fitness effects and mobile genetic element dynamics across Pseudomonas species. Fems Microbiology Ecology, 94 (1). fix172. ISSN 0168-6496

Hall, J.P.J., Brockhurst, M.A. and Harrison, E. orcid.org/0000-0002-2050-4631 (2017) Sampling the mobile gene pool : innovation via horizontal gene transfer in bacteria. Philosophical Transactions of the Royal Society B: Biological Sciences, 372 (1735). ISSN 0962-8436

Harrison, E. and Brockhurst, M.A. (2017) Ecological and Evolutionary Benefits of Temperate Phage: What Does or Doesn't Kill You Makes You Stronger. Bioessays, 39 (12). 1700112. ISSN 0265-9247

Stevenson, C., Hall, J.P.J., Harrison, E. et al. (2 more authors) (2017) Gene mobility promotes the spread of resistance in bacterial populations. ISME Journal, 11 (8). pp. 1930-1932. ISSN 1751-7362

Bottery, M.J., Wood, A.J. and Brockhurst, M.A. (2017) Adaptive modulation of antibiotic resistance through intragenomic coevolution. Nature Ecology and Evolution, 1. pp. 1364-1369. ISSN 2397-334X

Evans, R., Alessi, A.M., Bird, S. et al. (3 more authors) (2017) Defining the functional traits that drive bacterial decomposer community productivity. ISME Journal, 11 (7). pp. 1680-1687. ISSN 1751-7362

Hall, J.P.J., Brockhurst, M.A., Dytham, C. et al. (1 more author) (2017) The evolution of plasmid stability: Are infectious transmission and compensatory evolution competing evolutionary trajectories? Plasmid, 91. pp. 90-95. ISSN 0147-619X

Harrison, E.A., Hall, J.P.G., Paterson, S. et al. (2 more authors) (2017) Conflicting selection alters the trajectory of molecular evolution in a tripartite bacteria-plasmid-phage interaction. Molecular Ecology. ISSN 0962-1083

O'Brien, S., Williams, D., Fothergill, J.L. et al. (3 more authors) (2017) High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections. BMC Microbiology, 17 (30).

Davies, E.V., James, C.E., Brockhurst, M.A. et al. (1 more author) (2017) Evolutionary diversification of Pseudomonas aeruginosa in an artificial sputum model. BMC Microbiology, 17 (1). p. 3.

Hall, J.P., Williams, D., Paterson, S. et al. (2 more authors) (2017) Positive selection inhibits gene mobilization and transfer in soil bacterial communities. Nature Ecology and Evolution, 1. 1348-1353 . ISSN 2397-334X

Wright, R.C., Brockhurst, M.A. and Harrison, E. (2016) Ecological conditions determine extinction risk in co-evolving bacteria-phage populations. BMC Evolutionary Biology, 16 (1). p. 227.

Davies, E.V., James, C.E., Kukavica-Ibrulj, I. et al. (3 more authors) (2016) Temperate phages enhance pathogen fitness in chronic lung infection. The ISME Journal, 10 (10). pp. 2553-2555. ISSN 1751-7362

Dean, A.D., Minter, E.J.A., Sørensen, M.E.S. et al. (4 more authors) (2016) Host control and nutrient trading in a photosynthetic symbiosis. Journal of Theoretical Biology, 405. pp. 82-93. ISSN 0022-5193

King, K.C., Brockhurst, M.A., Vasieva, O. et al. (7 more authors) (2016) Rapid evolution of microbe-mediated protection against pathogens in a worm host. ISME Journal, 10 (8). pp. 1915-1924. ISSN 1751-7362

Hall, J.P.J., Wood, A.J., Harrison, E. et al. (1 more author) (2016) Source-sink plasmid transfer dynamics maintain gene mobility in soil bacterial communities. Proceedings of the National Academy of Sciences, 113 (29). pp. 8260-8265.

Davies, E.V., James, C.E., Williams, D. et al. (6 more authors) (2016) Temperate phages both mediate and drive adaptive evolution in pathogen biofilms. Proceedings of the National Academy of Sciences, 113 (29). pp. 8266-8271.

Winstanley, C., O’Brien, S. and Brockhurst, M.A. (2016) Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections. Trends in Microbiology, 24 (5). pp. 327-337. ISSN 0966-842X

Harrison, E., Dytham, C., Hall, J.P. et al. (4 more authors) (2016) Rapid compensatory evolution promotes the survival of conjugative plasmids. Mobile Genetic Elements, 6 (3). e1179074. ISSN 2159-2543

Kottara, A., Hall, J.P., Harrison, E. et al. (1 more author) (2016) Multi-host environments select for host-generalist conjugative plasmids. BMC Evolutionary Biology, 16. 70. ISSN 1471-2148

Bottery, M.J., Wood, A.J. and Brockhurst, M.A. (2016) Selective Conditions for a Multidrug Resistance Plasmid Depend on the Sociality of Antibiotic Resistance. Antimicrobial Agents and Chemotherapy, 60 (4). pp. 2524-2527. ISSN 0066-4804

Sørensen, M.E.S., Cameron, D.D. orcid.org/0000-0002-5439-6544, Brockhurst, M.A. et al. (1 more author) (2016) Metabolic constraints for a novel symbiosis. Royal Society Open Science, 3 (3). p. 150708.

Lowe, C.D., Minter, E.J., Cameron, D.D. et al. (1 more author) (2016) Shining a Light on Exploitative Host Control in a Photosynthetic Endosymbiosis. Current Biology, 26 (2). pp. 207-211. ISSN 0960-9822

Hall, J.P., Harrison, E., Lilley, A.K. et al. (3 more authors) (2015) Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects. Environmental Microbiology, 17 (12). pp. 5008-5022. ISSN 1462-2912

Harrison, E., Guymer, D., Spiers, A.J. et al. (2 more authors) (2015) Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum. Current Biology, 25 (15). pp. 2034-2039. ISSN 0960-9822

Harrison, E., Wood, A.J., Dytham, C. et al. (5 more authors) (2015) Bacteriophages limit the existence conditions for conjugative plasmids. MBio, 6 (3). e00586. ISSN 2150-7511

Williams, D., Evans, B., Haldenby, S. et al. (4 more authors) (2015) Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections. American Journal of Respiratory and Critical Care Medicine , 191 (7). pp. 775-785. ISSN 1073-449X

Taylor, T.B., Mulley, G., Dills, A.H. et al. (7 more authors) (2015) Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system. Science, 347 (6225). pp. 1014-1017. ISSN 0036-8075

Harrison, E., Laine, A.-L., Hietala, M. et al. (1 more author) (2013) Rapidly fluctuating environments constrain coevolutionary arms races by impeding selective sweeps. Proceedings of the Royal Society B: Biological Sciences, 280 (1764). 20130937. ISSN 0962-8452

Preprint

Buddle, J.E. orcid.org/0000-0002-7259-0527, Wright, R.C.T. orcid.org/0000-0002-8095-8256, Turner, C.E. orcid.org/0000-0002-4458-9748 et al. (3 more authors) (2023) Multiple evolutionary pathways lead to vancomycin resistance in Clostridioides difficile. [Preprint] (Submitted)