Browse by Academic Unit (A-Z)

Article

Aubrey, L.D. orcid.org/0000-0003-0420-8274, Ninkina, N. orcid.org/0000-0001-8570-5648, Ulamec, S.M. et al. (16 more authors) (2024) Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. Proceedings of the National Academy of Sciences, 121 (2). e2309700120. ISSN 0027-8424

Azam, AA, Kinder, JM, Khan, GN et al. (9 more authors) (2018) Production of membrane proteins for characterisation of their pheromone-sensing and antimicrobial resistance functions. European Biophysics Journal, 47 (7). pp. 723-737. ISSN 0175-7571

Baum, J, Chiti, F, De Simone, A et al. (9 more authors) (2019) Homage to Chris Dobson. Frontiers in Molecular Biosciences, 6. 137. ISSN 2296-889X

Benseny-Cases, N, Karamanos, TK, Hoop, CL et al. (2 more authors) (2019) Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation. The Journal of biological chemistry, 294. pp. 9392-9401. ISSN 0021-9258

Berry, A orcid.org/0000-0003-3502-0426 and Radford, SE orcid.org/0000-0002-3079-8039 (2018) Richard Nelson Perham. 27 April 1937—14 February 2015. Biographical Memoirs of Fellows of the Royal Society, 65. pp. 317-339. ISSN 0080-4606

Brown, MR, Radford, SE orcid.org/0000-0002-3079-8039 and Hewitt, E orcid.org/0000-0002-6238-6303 (2020) Modulation of β-amyloid fibril formation in Alzheimer’s disease by microglia and infection. Frontiers in Molecular Neuroscience, 13. 609073. ISSN 1662-5099

Bunce, SJ, Wang, Y, Radford, SE orcid.org/0000-0002-3079-8039 et al. (2 more authors) (2021) Structural insights into peptide self-assembly using photo-induced crosslinking experiments and discontinuous molecular dynamics. AIChE Journal, 67 (3). e17101. ISSN 0001-1541

Bunce, SJ, Wang, Y, Stewart, KL et al. (4 more authors) (2019) Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β₄₀ (Aβ₄₀) by the peptide fragment Aβ₁₆-₂₂. Science Advances, 5 (6). eaav8216. ISSN 2375-2548

Byrd, EJ orcid.org/0000-0002-9876-1400, Wilkinson, M orcid.org/0000-0001-5490-613X, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2023) Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry, 34 (3). pp. 493-504. ISSN 1044-0305

Byrne, MJ orcid.org/0000-0001-8111-4605, Steele, JFC, Hesketh, EL et al. (4 more authors) (2019) Combining Transient Expression and Cryo-EM to Obtain High-Resolution Structures of Luteovirid Particles. Structure, 27 (12). 1761-1770.e3. ISSN 0969-2126

Byrne, MJ orcid.org/0000-0001-8111-4605, Iadanza, MG, Perez, MA et al. (7 more authors) (2021) Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane. Nature Communications, 12 (1). 2791. ISSN 2041-1723

Calabrese, AN, Jackson, SM, Jones, LN et al. (10 more authors) (2017) Topological dissection of the membrane transport protein Mhp1 derived from cysteine accessibility and mass spectrometry. Analytical Chemistry, 89 (17). pp. 8844-8852. ISSN 0003-2700

Calabrese, AN and Radford, SE orcid.org/0000-0002-3079-8039 (2018) Mass spectrometry-enabled structural biology of membrane proteins. Methods, 147. pp. 187-205. ISSN 1046-2023

Cawood, E, Guthertz, N, Ebo, JS orcid.org/0000-0002-5684-4355 et al. (3 more authors) (2020) Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules. Journal of the American Chemical Society, 142 (49). pp. 20845-20854. ISSN 0002-7863

Cawood, EE, Karamanos, TK orcid.org/0000-0003-2297-540X, Wilson, AJ orcid.org/0000-0001-9852-6366 et al. (1 more author) (2021) Visualizing and trapping transient oligomers in amyloid assembly pathways. Biophysical Chemistry, 268. 106505. ISSN 0301-4622

Chau, CC orcid.org/0000-0002-3134-6798, Radford, SE orcid.org/0000-0002-3079-8039, Hewitt, EW orcid.org/0000-0002-6238-6303 et al. (1 more author) (2020) Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore. Nano Letters, 20 (7). pp. 5553-5561. ISSN 1530-6984

Chau, C orcid.org/0000-0002-3134-6798, Marcuccio, F orcid.org/0000-0003-4816-2896, Soulias, D orcid.org/0000-0003-4700-6744 et al. (5 more authors) (2022) Probing RNA Conformations Using a Polymer–Electrolyte Solid-State Nanopore. ACS Nano, 16 (12). pp. 20075-20085. ISSN 1936-0851

Ciano, L, Paradisi, A, Hemsworth, GR orcid.org/0000-0002-8226-1380 et al. (3 more authors) (2020) Insights from semi-oriented EPR spectroscopy studies into the interaction of lytic polysaccharide monooxygenases with cellulose. Dalton Transactions, 49 (11). pp. 3413-3422. ISSN 1477-9226

Cornwell, O, Bond, NJ, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2019) Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS. Analytical Chemistry, 91 (23). pp. 15163-15170. ISSN 0003-2700

Cornwell, O, Radford, SE orcid.org/0000-0001-9668-6366, Ashcroft, AE orcid.org/0000-0002-1676-123X et al. (1 more author) (2018) Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β₂-Microglobulin. Journal of The American Society for Mass Spectrometry, 29 (12). pp. 2413-2426. ISSN 1044-0305

Cornwell, O, Ault, JR orcid.org/0000-0002-5131-438X, Bond, NJ et al. (2 more authors) (2021) An investigation of D76N β₂-microglobulin using protein footprinting and structural mass spectrometry. Journal of the American Society for Mass Spectrometry, 32 (7). pp. 1583-1592. ISSN 1044-0305

Crossley, J.A. orcid.org/0000-0002-6656-1578, Allen, W.J. orcid.org/0000-0002-9513-4786, Watkins, D.W. orcid.org/0000-0003-3825-5036 et al. (5 more authors) (2024) Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec translocon. The EMBO Journal, 43 (1). pp. 1-13.

Deville, K, Gold, VAM, Robson, A et al. (5 more authors) (2011) The Oligomeric State and Arrangement of the Active Bacterial Translocon. Journal of Biological Chemistry, 286 (6). pp. 4659-4669. ISSN 0021-9258

Devine, PWA, Fisher, HC, Calabrese, AN et al. (6 more authors) (2017) Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. Journal of The American Society for Mass Spectrometry, 28 (9). pp. 1855-1862. ISSN 1044-0305

Dewison, K.M., Rowlinson, B., Machin, J.M. et al. (9 more authors) (2024) Residues 2-7 of α-synuclein regulate amyloid formation via lipid-dependent and -independent pathways. Proceedings of the National Academy of Sciences of USA. ISSN 0027-8424 (In Press)

Dobson, CL, Devine, PWA, Phillips, JJ et al. (24 more authors) (2016) Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Scientific Reports, 6. 38644. ISSN 2045-2322

Drulyte, I orcid.org/0000-0003-1117-7699, Obajdin, J, Trinh, CH et al. (4 more authors) (2019) Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. IUCrJ, 6 (6). pp. 1120-1133. ISSN 2052-2525

Farrance, OE, Paci, E orcid.org/0000-0002-4891-2768, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2015) Extraction of Accurate Biomolecular Parameters from Single-Molecule Force Spectroscopy Experiments. ACS Nano, 9 (2). pp. 1315-1324. ISSN 1936-0851

Fessl, T orcid.org/0000-0001-6969-4870, Watkins, D, Oatley, P et al. (7 more authors) (2018) Dynamic action of the Sec machinery during initiation, protein translocation and termination. eLife, 7. e35112. ISSN 2050-084X

Foley, MH, Déjean, G, Hemsworth, GR orcid.org/0000-0002-8226-1380 et al. (3 more authors) (2019) A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus. Journal of Molecular Biology, 431 (5). pp. 981-995. ISSN 0022-2836

Fowler, CA, Hemsworth, GR orcid.org/0000-0002-8226-1380, Cuskin, F et al. (5 more authors) (2018) Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae. Acta Crystallographica Section D: Structural Biology, 74 (10). pp. 946-955. ISSN 2059-7983

Fowler, CA, Sabbadin, F, Ciano, L et al. (6 more authors) (2019) Discovery, activity and characterisation of an AA10 lytic polysaccharide oxygenase from the shipworm symbiont Teredinibacter turnerae. Biotechnology for Biofuels, 12. ARTN: 232. ISSN 1754-6834

Frandsen, KEH, Tovborg, M, Jørgensen, CI et al. (15 more authors) (2019) Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. The Journal of Biological Chemistry, 294 (45). pp. 17117-17130. ISSN 0021-9258

Gallardo, R orcid.org/0000-0003-1584-3564, Ranson, NA orcid.org/0000-0002-3640-5275 and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Amyloid Structures: Much More Than Just A Cross-β Fold. Current Opinion in Structural Biology, 60. pp. 7-16. ISSN 0959-440X

Gallardo, R orcid.org/0000-0003-1584-3564, Iadanza, MG, Xu, Y et al. (4 more authors) (2020) Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nature Structural & Molecular Biology, 27 (11). pp. 1048-1056. ISSN 1545-9993

Good, SG, Dewison, KM, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2021) Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans. International Journal of Molecular Sciences, 22 (19). 10752. ISSN 1661-6596

Gregory, RC, Hemsworth, GR orcid.org/0000-0002-8226-1380, Turkenburg, JP et al. (3 more authors) (2016) Activity, stability and 3-D structure of the Cu(II) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens. Dalton Transactions, 45 (42). pp. 16904-16912. ISSN 1477-9226

Guthertz, N, van der Kant, R, Martinez, RM et al. (7 more authors) (2022) The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proceedings of the National Academy of Sciences (PNAS), 119 (22). e2200468119. ISSN 0027-8424

Haysom, SF, Machin, J, Whitehouse, JM et al. (9 more authors) (2023) Darobactin B Stabilises a Lateral‐Closed Conformation of the BAM Complex in E. coli Cells. Angewandte Chemie International Edition, 62 (34). ISSN 1433-7851

Heirbaut, M, Lermyte, F, Martin, EM et al. (4 more authors) (2017) Specific Sequences in the N-terminal Domain of Human Small Heat Shock Protein HSPB6 Dictate Preferential Heterooligomerization with the Orthologue HSPB1. Journal of Biological Chemistry, 292 (24). pp. 9944-9957. ISSN 0021-9258

Heirbaut, M, Lermyte, F, Martin, EM et al. (5 more authors) (2016) The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain. Archives of Biochemistry and Biophysics, 610. pp. 41-50. ISSN 0003-9861

Hemsworth, GR orcid.org/0000-0002-8226-1380, Ciano, L, Davies, GJ et al. (1 more author) (2018) Chapter Three - Production and spectroscopic characterization of lytic polysaccharide monooxygenases. Methods in Enzymology, 613. pp. 63-90. ISSN 0076-6879

Hemsworth, GR orcid.org/0000-0002-8226-1380, Moroz, OV, Fogg, MJ et al. (4 more authors) (2011) The Crystal Structure of the Leishmania major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine. Journal of Biological Chemistry, 286 (18). pp. 16470-16481. ISSN 0021-9258

Hethershaw, EL orcid.org/0000-0002-4366-278X, Adamson, PJ, Smith, KA orcid.org/0000-0001-5695-7117 et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933

Hoop, CL, Zhu, J, Bhattacharya, S et al. (3 more authors) (2020) Collagen I weakly interacts with the β-sheets of β2-microglobulin and enhances conformational exchange to induce amyloid formation. Journal of the American Chemical Society, 142 (3). pp. 1321-1331. ISSN 0002-7863

Iadanza, MG, Jackson, MP, Hewitt, EW orcid.org/0000-0002-6238-6303 et al. (2 more authors) (2018) A new era for understanding amyloid structures and disease. Nature Reviews Molecular Cell Biology, 19 (12). pp. 755-773. ISSN 1471-0072

Iadanza, MG, Silvers, R, Boardman, J et al. (7 more authors) (2018) The structure of a β₂-microglobulin fibril suggests a molecular basis for its amyloid polymorphism. Nature Communications, 9. 4517. ISSN 2041-1723

Iadanza, MG, Schiffrin, B, White, P orcid.org/0000-0001-7536-4552 et al. (9 more authors) (2020) Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs. Communications Biology, 3. 766. ISSN 2399-3642

Jackson, MP and Hewitt, EW orcid.org/0000-0002-6238-6303 (2017) Why are Functional Amyloids Non-Toxic in Humans? Biomolecules, 7 (4). 71. ISSN 2218-273X

Karamanos, TK, Jackson, MP, Calabrese, AN et al. (6 more authors) (2019) Structural mapping of oligomeric intermediates in an amyloid assembly pathway. eLife, 8. e46574. ISSN 2050-084X

Karamanos, TK, Kalverda, AP, Thompson, GS et al. (1 more author) (2014) Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly. Molecular Cell, 55 (2). pp. 214-226. ISSN 1097-2765

Karamanos, TK, Pashley, CL, Kalverda, AP et al. (4 more authors) (2016) A population shift between sparsely populated folding intermediates determines amyloidogenicity. Journal of the American Chemical Society, 138 (19). pp. 6271-6280. ISSN 0002-7863

Karamanos, TK orcid.org/0000-0003-2297-540X, Kalverda, AP and Radford, SE orcid.org/0000-0002-3079-8039 (2022) Generating Ensembles of Dynamic Misfolding Proteins. Frontiers in Neuroscience, 16. 881534. ISSN 1662-453X

Knight, PD, Karamanos, TK, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2018) Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. European Journal of Mass Spectrometry, 24 (1). pp. 129-140. ISSN 1469-0667

Kontziampasis, D orcid.org/0000-0002-6787-8892, Klebl, DP, Iadanza, MG et al. (7 more authors) (2019) A cryo-EM grid preparation device for time-resolved structural studies. IUCrJ, 6 (6). ISSN 2052-2525

Lauwers, E, Lalli, G, Brandner, S et al. (34 more authors) (2020) Potential human transmission of amyloid β pathology: surveillance and risks. Lancet Neurology, 19 (10). pp. 872-878. ISSN 1474-4422

Louros, N. orcid.org/0000-0002-4030-1022, Wilkinson, M. orcid.org/0000-0001-5490-613X, Tsaka, G. et al. (14 more authors) (2024) Local structural preferences in shaping tau amyloid polymorphism. Nature Communications, 15. 1028. ISSN 2041-1723

Machin, J.M., Kalli, A.C. orcid.org/0000-0001-7156-9403, Ranson, N.A. orcid.org/0000-0002-3640-5275 et al. (1 more author) (2023) Protein–lipid charge interactions control the folding of outer membrane proteins into asymmetric membranes. Nature Chemistry, 15 (12). pp. 1754-1764. ISSN 1755-4330

Marcuccio, F orcid.org/0000-0003-4816-2896, Soulias, D orcid.org/0000-0003-4700-6744, Chau, CCC orcid.org/0000-0002-3134-6798 et al. (4 more authors) (2023) Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer–Electrolyte Nanopore. ACS Nanoscience Au, 3 (2). pp. 172-181. ISSN 2694-2496

Martin, EM, Jackson, MP, Gamerdinger, M et al. (6 more authors) (2018) Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins. Journal of Biological Chemistry, 293 (22). pp. 8554-8568. ISSN 0021-9258

Maya-Martinez, R, Xu, Y, Guthertz, N et al. (5 more authors) (2022) Dimers of D76N-β₂-microglobulin display potent antiamyloid aggregation activity. Journal of Biological Chemistry, 298 (12). 102659. ISSN 0021-9258

Mclure, RJ, Radford, SE orcid.org/0000-0002-3079-8039 and Brockwell, DJ orcid.org/0000-0002-0802-5937 (2022) High-throughput directed evolution: a golden era for protein science. Trends in Chemistry, 4 (5). pp. 378-391. ISSN 2589-5974

Milardi, D, Gazit, E, Radford, SE orcid.org/0000-0002-3079-8039 et al. (7 more authors) (2021) Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes. Chemical Reviews. ISSN 0009-2665

Nahass, GR, Sun, Y, Xu, Y et al. (12 more authors) (2021) Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium. Journal of Molecular Biology, 433 (8). 166878. ISSN 0022-2836

Radford, SE orcid.org/0000-0002-3079-8039 and Summers, MF (2023) Changing Shape of Molecules. Journal of Molecular Biology, 435 (11). 168092. ISSN 0022-2836

Rodríguez-Alonso, R, Létoquart, J, Nguyen, VS et al. (7 more authors) (2020) Structural insight into the formation of lipoprotein-β-barrel complexes. Nature Chemical Biology, 16. pp. 1019-1025. ISSN 1552-4450

Roth, C, Chan, S, Offen, WA et al. (7 more authors) (2017) Structural and functional insight into human O-GlcNAcase. Nature Chemical Biology, 13 (6). pp. 610-612. ISSN 1552-4469

Ruff, KM, Choi, YH, Cox, D et al. (6 more authors) (2022) Sequence grammar underlying the unfolding and phase separation of globular proteins. Molecular Cell, 82 (17). 3193-3208.e8. ISSN 1097-2765

Sabbadin, F, Hemsworth, GR orcid.org/0000-0002-8226-1380, Ciano, L et al. (17 more authors) (2018) An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion. Nature Communications, 9. 756. ISSN 2041-1723

Santos, J., Cuellar, J., Pallares, I. et al. (15 more authors) (2024) A targetable N-terminal motif orchestrates α-Synuclein oligomer to fibril conversion. Journal of the American Chemical Society. ISSN 0002-7863 (In Press)

Scarff, CA orcid.org/0000-0001-6168-0060, Fuller, MJG, Thompson, RF et al. (1 more author) (2018) Variations on Negative Stain Electron Microscopy Methods: Tools for Tackling Challenging Systems. Journal of Visualized Experiments (132). e57199.

Schiffrin, B, Machin, JM, Karamanos, TK orcid.org/0000-0003-2297-540X et al. (4 more authors) (2022) Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding. Communications Biology, 5. 560. ISSN 2399-3642

Schiffrin, B, Radford, SE orcid.org/0000-0002-3079-8039, Brockwell, DJ orcid.org/0000-0002-0802-5937 et al. (1 more author) (2020) PyXlinkViewer: A flexible tool for visualization of protein chemical crosslinking data within the PyMOL molecular graphics system. Protein Science, 29 (8). pp. 1851-1857. ISSN 0961-8368

Shen, K, Gamerdinger, M, Chan, R et al. (12 more authors) (2019) Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. Molecular Cell, 74 (4). 729-741.e7. ISSN 1097-2765

Smith, HI, Guthertz, N, Cawood, EE et al. (3 more authors) (2020) The role of the IT-state in D76N β2-microglobulin amyloid assembly: a crucial intermediate or an innocuous bystander? Journal of Biological Chemistry. jbc.RA120.014901. ISSN 0021-9258

Stewart, KL orcid.org/0000-0001-8845-9155, Hughes, E, Yates, EA et al. (2 more authors) (2017) Molecular Origins of the Compatibility Between Glycosaminoglycans and Aβ40 Amyloid Fibrils. Journal of Molecular Biology, 429 (16). pp. 2449-2462. ISSN 0022-2836

Stewart, KL orcid.org/0000-0001-8845-9155 and Radford, SE orcid.org/0000-0002-3079-8039 (2017) Amyloid Plaques Beyond Aβ: A Survey of the Diverse Modulators of Amyloid Aggregation. Biophysical Reviews, 9 (4). pp. 405-419. ISSN 1867-2450

Stull, F, Koldewey, P, Humes, JR orcid.org/0000-0002-1407-7880 et al. (2 more authors) (2016) Substrate protein folds while it is bound to the ATP-independent chaperone Spy. Nature Structural & Molecular Biology, 23 (1). pp. 53-58. ISSN 1545-9993

Tamura, K, Hemsworth, GR orcid.org/0000-0002-8226-1380, Dejean, G et al. (7 more authors) (2017) Molecular mechanism by which prominent human gut Bacteroidetes utilize mixed-linkage beta-glucans, major health-promoting cereal polysaccharides. Cell Reports, 21 (2). pp. 417-430. ISSN 2211-1247

Tamura, K, Hemsworth, GR orcid.org/0000-0002-8226-1380, Déjean, G et al. (7 more authors) (2017) Correction to: Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides. Cell Reports, 21 (7). p. 2030. ISSN 2211-1247

Thompson, RF, Iadanza, MG, Hesketh, EL et al. (2 more authors) (2018) Collection, pre-processing and on-the-fly analysis of data for high-resolution, single-particle cryo-electron microscopy. Nature Protocols, 14. pp. 100-118. ISSN 1754-2189

Thuenemann, EC, Byrne, MJ orcid.org/0000-0001-8111-4605, Peyret, H et al. (9 more authors) (2021) A Replicating Viral Vector Greatly Enhances Accumulation of Helical Virus-Like Particles in Plants. Viruses, 13 (5). 885. ISSN 1999-4915

Tipping, KW, Karamanos, TK orcid.org/0000-0003-2297-540X, Jakhria, T et al. (6 more authors) (2015) pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers. Proceedings of the National Academy of Sciences, 112 (18). pp. 5691-5696. ISSN 0027-8424

Townsend, D, Hughes, E, Akien, G et al. (4 more authors) (2018) Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin. Journal of Biological Chemistry, 293 (33). pp. 12877-12893. ISSN 0021-9258

Townsend, D, Hughes, E, Stewart, KL et al. (3 more authors) (2018) Orientation of a Diagnostic Ligand Bound to Macroscopically Aligned Amyloid-ß Fibrils Determined by Solid-state NMR. Journal of Physical Chemistry Letters, 9 (22). pp. 6611-6615. ISSN 1948-7185

Ulamec, SM, Brockwell, DJ orcid.org/0000-0002-0802-5937 and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins. Frontiers in Neuroscience, 14 (611285). ISSN 1662-4548

Ulamec, SM, Maya-Martinez, R, Byrd, EJ orcid.org/0000-0002-9876-1400 et al. (9 more authors) (2022) Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature Communications, 13. 4986. ISSN 2041-1723

Ulamec, SM and Radford, SE orcid.org/0000-0002-3079-8039 (2020) Spot the Difference: Function versus Toxicity in Amyloid Fibrils. Trends in Biochemical Sciences. ISSN 0968-0004

Vorobieva, AA, White, P orcid.org/0000-0001-7536-4552, Liang, B et al. (16 more authors) (2021) De novo design of transmembrane β-barrels. Science, 371 (6531). eabc8182. ISSN 0036-8075

Walko, M, Hewitt, E orcid.org/0000-0002-6238-6303, Radford, SE orcid.org/0000-0001-9668-6366 et al. (1 more author) (2019) Design and Synthesis of Cysteine-Specific Labels for Photo-Crosslinking Studies. RSC Advances, 9 (14). pp. 7610-7614. ISSN 2046-2069

Wang, Y, Bunce, SJ, Radford, SE orcid.org/0000-0001-9668-6366 et al. (3 more authors) (2019) Thermodynamic phase diagram of amyloid-β (16-22) peptide. Proceedings of the National Academy of Sciences of the United States of America, 116 (6). pp. 2091-2096. ISSN 0027-8424

Watkinson, TG, Calabrese, AN, Ault, JR orcid.org/0000-0002-5131-438X et al. (2 more authors) (2017) FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins. Journal of the American Society for Mass Spectrometry, 28 (1). pp. 50-55. ISSN 1044-0305

White, P, Haysom, SF, Iadanza, MG et al. (12 more authors) (2021) The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nature Communications, 12. 4174. ISSN 2041-1723

Wilkinson, M orcid.org/0000-0001-5490-613X, Gallardo, RU, Martinez, RM et al. (5 more authors) (2023) Disease-relevant β2-microglobulin variants share a common amyloid fold. Nature Communications, 14. 1190. ISSN 2041-1723

Willis, L.F. orcid.org/0000-0001-6616-3716, Toprani, V., Wijetunge, S. et al. (7 more authors) (2024) Exploring a Role for Flow-Induced Aggregation Assays in Platform Formulation Optimisation for Antibody-Based Proteins. Journal of Pharmaceutical Sciences, 113 (3). pp. 625-636. ISSN 0022-3549

Willis, LF orcid.org/0000-0001-6616-3716, Kumar, A, Jain, T et al. (6 more authors) (2020) The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies. Engineering Reports, 2 (5). e12147. ISSN 2577-8196

Wu, K, Minshull, TC, Radford, SE orcid.org/0000-0002-3079-8039 et al. (2 more authors) (2022) Trigger factor both holds and folds its client proteins. Nature Communications, 13. 4126. ISSN 2041-1723

Xu, Y, Maya-Martinez, R, Guthertz, N et al. (6 more authors) (2022) Tuning the rate of aggregation of hIAPP into amyloid using smallmolecule modulators of assembly. Nature Communications, 13. 1040. ISSN 2041-1723

Xu, Y, Maya-Martinez, R and Radford, S orcid.org/0000-0002-3079-8039 (2022) Controlling amyloid formation of intrinsically disordered proteins and peptides: Slowing down or speeding up? Essays in Biochemistry, 66 (7). pp. 959-975. ISSN 0071-1365

Young, LM, Ashcroft, AE and Radford, SE orcid.org/0000-0002-3079-8039 (2017) Small molecule probes of protein aggregation. Current Opinion in Chemical Biology, 39. pp. 90-99. ISSN 1367-5931

Young, LM, Saunders, JC, Mahood, RA et al. (6 more authors) (2015) Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry. Nature Chemistry, 7 (1). pp. 73-81. ISSN 1755-4330

Young, LM, Tu, LH, Raleigh, D et al. (2 more authors) (2017) Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers. Chemical Science, 8 (7). pp. 5030-5040. ISSN 2041-6520

Book Section

Fessl, T, Crossley, JA, Watkins, D et al. (6 more authors) (2021) Dynamics of Membrane Proteins Monitored by Single-Molecule Fluorescence Across Multiple Timescales. In: Postis, VLG and Goldman, A, (eds.) Biophysics of Membrane Proteins: Methods and Protocols. Methods in Molecular Biology, 2168 . Humana , New York, NY , pp. 273-297. ISBN 978-1-0716-0723-7

Scarff, CA orcid.org/0000-0001-6168-0060, Ashcroft, AE orcid.org/0000-0002-1676-123X and Radford, SE orcid.org/0000-0002-3079-8039 (2016) Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS). In: Eliezer, D, (ed.) Protein Amyloid Aggregation: methods and protocols. Methods in Molecular Biology, 1345 . Springer (Humana Press) , New York, N.Y., U.S.A. , pp. 115-132. ISBN 978-1-4939-2977-1

Conference or Workshop Item

Radford, S. orcid.org/0000-0002-3079-8039 60 years of the Colworth Medal: a view across the decades (part 3). In: Webinar to celebrate 60th anniversary of the Biochemistry Society Colworth Medal, 14 Sep 2023, Online. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Building a wall: Molecular insights into how bacteria do it. In: American Chemical Society Spring 2023 Meeting, 23-26 Mar 2023, Indianapolis, USA. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Combatting Amyloid Formation by Targeting Early Interactions in Assembly. In: Biophysics Society & Cell Press Webinar: Biophysics of neurodegenerative diseases, 09 Mar 2023, Online. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Early Steps in Amyloid Assembly: The Achilles Heel of a Disease Mechanism? In: Seminar: Early Steps in Amyloid Assembly: The Achilles Heel of a Disease Mechanism?, 26 Jan 2023, Stockholm University, Sweden. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Folding a Protein: Nature’s Origami. In: Seminar: Folding a Protein: Nature’s Origami, 18 Mar 2022, Faculty of Science, University of Liège, Belgium. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 How does an IDP aggregate into amyloid? Insights from structural approaches. In: Proteostasis Consortium 2023 Seminars, 11 Oct 2023, Online. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 JMB symposium and full editorial board meeting, Surveying the Energy Landscape of Amyloid Formation. In: Journal of Molecular Biology symposium and full board meeting, 15-16 Jun 2023, San Diego, CA, USA. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Keynote 1: Sticking together: the molecular mechanisms of protein self-assembly and how can it be controlled. In: EMBO Workshop on Protein Quality Control: From molecular mechanisms to therapeutic intervention, 21-26 May 2023, Srebreno-Dubrovnik, Croatia. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Protein Folding Symposium as part of the International Conference on Biological Physics (ICBP), Seoul, South Korea, main meeting, “Building a wall: Molecular insights into how bacteria do it". In: International Conference on Biological Physics (ICBP), 14-18 Aug 2023, Seoul, Korea. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Protein Folding Symposium as part of the International Conference on Biological Physics (ICBP), Seoul, South Korea, satellite meeting, “Tricks of the Trade: How to probe amyloid formation mechanisms and unleash opportunities for intervention (for the satellite meeting), 14 August 2023. In: International Conference on Biological Physics (ICBP), 14-18 Aug 2023, Seoul, South Korea. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Protein Folding, Aggregation and Compartmentalization, “Seeing amyloid: beautiful structures and complex assembly mechanisms". In: FEBS Summer School, 01-08 Sep 2023, Spetses, Greece. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Rare events and increasing opportunities: Towards combating amyloid disease. In: BioSoft Colloquium, 23 Feb 2023, Forschungszentrum Jülich (Online). (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Seeing the structural mechanism of amyloid formation. In: 49th Lorne Conference on Protein Structure and Function 2024, 04-08 Feb 2024, Lorne, Australia. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Sequence and structural features that control aggregation into amyloid. In: 5th Düsseldorf-Jülich Symposium on Neurodegenerative Diseases: "Amyloid, from early aggregation steps to clinical trials and new concepts", 07 Dec 2023, Düsseldorf, Germany. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Surveying the Structural Mechanisms of Amyloid Formation. In: Seminar at University of Cambridge for Ritwick Sarwarkar, 27 Nov 2023, Cambridge, UK. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Surveying the energy landscape of amyloid formation. In: PhasAGE International Conference, 18-20 Oct 2023, Porto, Portugal. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Watching Amyloid Formation: Structural Insights and Opportunities for Intervention in Disease. In: Seminar for UCLouvain, Brussels, 26 Oct 2023, UCLouvain, Brussels. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Watching the structural evolution of a protein into amyloid: A feat of protein folding. In: American Chemical Society Spring 2023 Meeting, 23-28 Mar 2023, Indianapolis, USA. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 Webinar for AFMB, Marseille, “Sequence and structural features that control aggregation into amyloid". In: Webinar for The Architecture et Fonction des Macromolécules Biologiques (AFMB), Marseille, “Sequence and structural features that control aggregation into amyloid", 26 Jun 2023, Online. (Unpublished)

Radford, S. orcid.org/0000-0002-3079-8039 What a difference a day/residue makes. In: Cellular Machineries of Protein Folding, Assembly and Transport: Ulrich and Manajit Hartl birthday/retirement symposium, 25-28 Feb 2024, Schloss Ringberg, Germany. (Unpublished)