Items where Funder is CANCER RESEARCH UK (CRUK).

The University of Sheffield

Guo, X., Long, J., Zeng, C. et al. (112 more authors) (2015) Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk. Cancer Epidemiology, Biomarkers and Prevention, 24 (11). pp. 1680-1691. ISSN 1055-9965

Day, F.R., Thompson, D.J., Helgason, H. et al. (219 more authors) (2017) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6). pp. 834-841. ISSN 1061-4036

Westbrook, J.A., Cairns, D.A., Peng, J. et al. (10 more authors) (2016) CAPG and gipc1: Breast cancer biomarkers for bone metastasis development and treatment. Journal of the National Cancer Institute, 108 (4). ISSN 0027-8874

Moore, H.J., Nixon, C., Tariq, A. et al. (10 more authors) (2016) Evaluating a computer aid for assessing stomach symptoms (ECASS): study protocol for a randomised controlled trial. Trials, 17 (1). ISSN 1745-6215

Muthana, M., Kennerley, A.J., Hughes, R. et al. (12 more authors) (2015) Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting. Nature Communications, 6. 8009.

Reynolds, S. orcid.org/0000-0002-6463-8471, Metcalf, S., Cochrane, E.J. et al. (4 more authors) (2017) Direct Arterial Injection of Hyperpolarized 13C-Labeled Substrates into Rat Tumors for Rapid MR Detection of Metabolism with Minimal Substrate Dilution. Magnetic Resonance in Medicine. ISSN 0740-3194

Wang, N., Docherty, F., Brown, H.K. et al. (7 more authors) (2015) Mitotic quiescence, but not unique "stemness," marks the phenotype of bone metastasis-initiating cells in prostate cancer. FASEB Journal, 29 (8). pp. 3141-3150. ISSN 0892-6638

Johnson, C.A. and Collis, S.J. orcid.org/0000-0002-7874-1891 (2016) Ciliogenesis and the DNA damage response: A stressful relationship. Cilia, 5 (19). ISSN 2046-2530

Staples, C.J., Barone, G., Myers, K.N. et al. (10 more authors) (2016) MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response. Cell Reports, 16. pp. 1-11. ISSN 2211-1247

Myers, K.N., Barone, G., Ganesh, A. et al. (6 more authors) (2016) The bornavirus-derived human protein EBLN1 promotes efficient cell cycle transit, microtubule organisation and genome stability. Scientific Reports, 6. p. 35548. ISSN 2045-2322

Brown, A.W., Fisher, M., Tozer, G.M. et al. (2 more authors) (2016) Sydnone Cycloaddition Route to Pyrazole-Based Analogs of Combretastatin A4. Journal of Medicinal Chemistry, 59 (20). pp. 9473-9488. ISSN 0022-2623

Patterson, K., Arya, L., Bottomley, S. et al. (4 more authors) (2016) Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy. Oncotarget, 7. pp. 76140-76150. ISSN 1949-2553

Whyte, S. orcid.org/0000-0002-7963-2523, Pollard, D. and Cree, I. (2016) Generic Cancer Screen - Economic modelling report. Report. Health Economics & Decision Science (HEDS) Discussion Paper Series (16:11). ScHARR, University of Sheffield , University of Sheffield.

Wyszynski, A., Hong, C.C., Lam, K. et al. (107 more authors) (2016) An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Human Molecular Genetics , 25 (17). pp. 3863-3876. ISSN 0964-6906

Buykx, P., Li, J., Gavens, L. et al. (3 more authors) (2018) Self-reported knowledge, correct knowledge and use of UK drinking guidelines among a representative sample of the English population. Alcohol and Alcoholism, 53 (4). pp. 453-460. ISSN 0735-0414

Cree, I., Uttley, L., Woods, H.B. et al. (11 more authors) (2017) The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review. BMC Cancer, 17. 697.

ABCTB Investigators, EMBRACE, GEMO Study Collaborators et al. (3 more authors) (2017) Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics, 49 (12). pp. 1767-1778. ISSN 1061-4036

NBCS Collaborators, ABCTB Investigators and ConFab/AOCS Investigators (2017) Association analysis identifies 65 new breast cancer risk loci. Nature, 551. pp. 92-94. ISSN 0028-0836

Rudolf, A., Song, M., Brook, M.N. et al. (48 more authors) (2018) Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. International Journal of Epidemiology, 47 (2). pp. 526-536. ISSN 0300-5771

Jiao, X., Aravidis, C., Marikkannu, R. et al. (103 more authors) (2017) PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget, 8. pp. 102769-102782. ISSN 1949-2553

O'Connor, J.P.B., Aboagye, E.O., Adams, J.E. et al. (74 more authors) (2017) Imaging biomarker roadmap for cancer studies. Nature Reviews Clinical Oncology, 14. pp. 169-186. ISSN 1759-4774

Bluff, J.E., Reynolds, S. orcid.org/0000-0002-6463-8471, Metcalf, S. et al. (8 more authors) (2015) Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate. Radiotherapy and Oncology, 116 (3). pp. 392-399. ISSN 0167-8140

Kanthou, C., Dachs, G.U., Lefley, D.V. et al. (8 more authors) (2014) Tumour Cells Expressing Single VEGF Isoforms Display Distinct Growth, Survival and Migration Characteristics. PLoS ONE, 9 (8). e104015. ISSN 1932-6203

Li, Y., Xiao, X., Han, Y. et al. (73 more authors) (2018) Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population. Carcinogenesis, 39 (3). pp. 336-346. ISSN 0143-3334

Daniels, S.L., Burghel, G.J., Chambers, P. et al. (9 more authors) (2016) Levels of DNA methylation vary at CpG sites across the BRCA1 promoter, and differ according to triple negative and "BRCA-like" status, in both blood and tumour DNA. PLoS One. ISSN 1932-6203

Barone, G., Staples, C.J., Ganesh, A. et al. (9 more authors) (2016) Human CDK18 promotes replication stress signaling and genome stability. Nucleic Acids Research. ISSN 0305-1048

Li, Y., Xiao, X., Bossé, Y. et al. (77 more authors) (2019) Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development. Oncotarget, 10 (19). pp. 1760-1774. ISSN 1949-2553

Gotham, V.J., Hobbs, M.C., Burgin, R. et al. (3 more authors) (2016) Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay. Organic & Biomolecular Chemistry, 14 (5). pp. 1559-1563. ISSN 1477-0520

Sung, H., Garcia-Closas, M., Chang-Claude, J. et al. (33 more authors) (2016) Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers. British Journal of Cancer, 114 (3). pp. 298-304. ISSN 0007-0920

Gennarini, G. and Furley, A. orcid.org/0000-0001-5549-8668 (2017) Cell adhesion molecules in neural development and disease. Molecular and Cellular Neuroscience, 81. pp. 1-3. ISSN 1044-7431

Bossé, Y., Li, Z., Xia, J. et al. (45 more authors) (2020) Transcriptome‐wide association study reveals candidate causal genes for lung cancer. International Journal of Cancer, 146 (7). pp. 1862-1878. ISSN 0020-7136

Ferreiro-Iglesias, A., Lesseur, C., McKay, J. et al. (70 more authors) (2018) Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. Nature Communications, 9 (1). 3927. ISSN 2041-1723

Lei, J., Rudolph, A., Moysich, K.B. et al. (67 more authors) (2016) Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium. Human Genetics, 135 (1). pp. 137-154. ISSN 0340-6717

Hamdi, Y., Soucy, P., Adoue, V. et al. (93 more authors) (2016) Association of Breast Cancer Risk with Genetic Variants Showing Differential Allelic Expression: Identification of a Novel Breast Cancer Susceptibility Locus at 4q21. Oncotarget, 7. pp. 80140-80163. ISSN 1949-2553

Zeng, C., Guo, X., Long, J. et al. (234 more authors) (2016) Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research, 18 (1). 64. ISSN 1465-542X

Barrdahl, M. orcid.org/0000-0003-4661-0763, Rudolph, A. orcid.org/0000-0001-7520-2035, Hopper, J.L. et al. (45 more authors) (2017) Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium. International Journal of Cancer, 141 (9). pp. 1830-1840. ISSN 0020-7136

Holen, I. orcid.org/0000-0002-8759-6913, Walker, M., Nutter, F. et al. (4 more authors) (2016) Oestrogen receptor positive breast cancer metastasis to bone: inhibition by targeting the bone microenvironment in vivo. Clinical & Experimental Metastasis, 33 (3). pp. 211-224. ISSN 0262-0898

Schmidt, M.J., Cox, A. orcid.org/0000-0002-5138-1099, Hogervorst, F. et al. (81 more authors) (2016) Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. Journal of Clinical Oncology, 34 (23). pp. 2750-2760. ISSN 0732-183X

Zhao, Z., Wen, W., Michailidou, K. et al. (115 more authors) (2016) Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry. Cancer Causes and Control. pp. 1-15. ISSN 0957-5243

Ghoussaini, M, French, J.D., Michailidou, K. et al. (122 more authors) (2016) Evidence that the 5p12 variant rs10941679 confers susceptibility to estrogen receptor positive breast cancer through FGF10 and MRPS30 regulation. American Journal of Human Genetics, 99 (4). pp. 903-911. ISSN 0002-9297

Horne, H.N., Chung, C.E., Zhang, H. et al. (112 more authors) (2016) Fine-mapping of the 1p11.2 breast cancer susceptibility locus. PLoS One, 11 (8). e0160316. ISSN 1932-6203

Shi, J., Zhang, Y., Zheng, W. et al. (125 more authors) (2016) Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer. International Journal of Cancer, 139 (6). pp. 1303-1317. ISSN 0020-7136

Lawrenson, K., Cox, A. orcid.org/0000-0002-5138-1099 and et al. (2016) Functional Mechanisms Underlying Pleiotropic Risk Alleles At The 19p13.1 Breast-Ovarian Cancer Susceptibility Locus. Nature Communications. ISSN 2041-1723

Muranen, T.A., Greco, D., Blomqvist, C et al. (10 more authors) (2016) Genetic modifiers of CHEK2*1100delC-associated breast cancer risk. Genetics in Medicine. ISSN 1098-3600

Guo, Y., Warren Andersen, S., Shu, X.O. et al. (108 more authors) (2016) Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. PLoS Medicine, 13 (8). e1002105. ISSN 1549-1277

Kar, S.P., Beesley, J., Cox, A. orcid.org/0000-0002-5138-1099 et al. (1 more author) (2016) Genome-wide Meta-analyses of Breast, Ovarian and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by At Least Two Cancer Types. Cancer Discovery, 6 (9). pp. 1052-1067. ISSN 2159-8274

Couch, F.J., Kuchenbaecker, K.B. orcid.org/0000-0002-5138-1099 and Et al (2016) Identification of four novel susceptibility loci for estrogen receptor negative breast cancer. Nature Communications, 7. 11375 . ISSN 2041-1723

Day, FR, Ruth, KS, Thompson, DJ et al. (240 more authors) (2015) Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47 (11). ISSN 1061-4036

Southey, M.C., Goldgar, D., Cox, A. orcid.org/0000-0002-5138-1099 et al. (1 more author) (2016) PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. Journal of Medical Genetics. 103839. ISSN 0022-2593

Pelttari, L.M., Khan, S. orcid.org/0000-0002-5138-1099 and et al. (2016) RAD51B in Familial Breast Cancer. PLoS One, 11 (5). e0153788. ISSN 1932-6203

Liu, J, Lončar, I, Collée, JM et al. (97 more authors) (2016) rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. Scientific Reports, 6. p. 36874. ISSN 2045-2322

Petridis, C., Brook, M.N., Shah, V. et al. (92 more authors) (2016) Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Research, 18 (1). 22. ISSN 1465-542X

Berndt, S.I., Camp, N.J., Skibola, C.F. et al. (123 more authors) (2016) Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nature Communications, 7. 10933. ISSN 2041-1723

Camp, N.J., Lin, W.Y., Bigelow, A. et al. (23 more authors) (2016) Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus. Cancer Research, 76 (7). pp. 1916-1925. ISSN 0008-5472