Pluck, G., Lekka, N.P., Sarkar, S. et al. (4 more authors) (2013) Clinical and neuropsychological aspects of non-fatal self-harm in schizophrenia. European Psychiatry, 28 (6). 344 - 348.
Abstract
Purpose To investigate demographic, clinical and neuropsychological aspects of self-harm in schizophrenia and identify which are independently predictive of and therefore the most relevant to clinical intervention.
Subjects and methods Eighty-seven patients with schizophrenia were interviewed regarding substance misuse, depression, hopelessness, negative/positive symptoms and illness insight. Neuropsychological assessment included premorbid IQ, continuous performance test, cognitive-motor and trait impulsivity. A prospective three-month review of medical records was also undertaken.
Results Fifty-nine patients (68%) reported past self-harm (including attempted suicide). Those with past self-harm, compared to those without, were significantly more likely to report depression, hopelessness, impulsivity, a family history of self-harm, polysubstance abuse and had higher premorbid IQ. Logistic regression revealed that depression, higher premorbid IQ and polysubstance abuse were independently linked to self-harm. Five participants attempted self-harm during the 3-month prospective follow-up period. These all had a history of past self-harm and were significantly more likely to have been depressed at the initial interview than those who did not go on to self-harm.
Discussion and conclusions Independent predictors of self-harm in schizophrenia are premorbid IQ and polysubstance abuse. In addition, depression was both independently associated with past self-harm and predictive of self-harm in the follow-up period.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2013 Elsevier. This is an author produced version of a paper subsequently published in European Psychiatry. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Schizophrenia; Self-harm; Depression; Substance abuse; IQ; Suicide |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Social Sciences (Sheffield) > Information School (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Apr 2014 14:34 |
Last Modified: | 11 Apr 2017 10:03 |
Published Version: | http://dx.doi.org/10.1016/j.eurpsy.2012.08.003 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.eurpsy.2012.08.003 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:78618 |