Clarke, A. orcid.org/0000-0003-0693-0340, Hallett, N. orcid.org/0000-0003-3115-8831, Brown, Y. et al. (5 more authors) (2026) Key protective factors that mitigate the impact of childhood trauma on poor mental health in adulthood: a scoping review protocol. BMJ Open, 16 (2). e112097. ISSN: 2044-6055
Abstract
Introduction
A significant proportion of adults in England and Wales report experiencing childhood trauma, which is often associated with poor health and negative social outcomes including a significant increase in the risk of poor mental health outcomes in adulthood. This proposed scoping review adopts a broad definition of childhood trauma and applies both a salutogenic framework and ecological systems theory to explore how protective factors at five ecological levels can support mental well-being. The review will also examine how protective factors vary across different population groups and contexts.
Methods and analysis
The scoping review will follow the Joanna Briggs Institute (JBI) protocol for scoping reviews. The databases that will be searched are Embase, PubMed, Web of Science, PsycINFO, CINAHL and Medline. Studies will be included if they include protective factors and involve adults aged 18 and over who have experienced childhood trauma, whether self-identified, retrospectively self-reported or measured using a validated instrument. Studies will be excluded if they focus on participants under the age of 18.
All search results will be uploaded to Covidence, duplicates removed, and titles/abstracts screened by at least two reviewers based on inclusion criteria. Full texts of potentially relevant sources will be imported into EndNote 21. Reasons for exclusions will be documented and disagreements resolved through discussion or a third reviewer. The full process will be reported using a Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram. Data will be extracted by at least two reviewers using a tool developed by the team based on the JBI guidance. A best-fit framework analysis will be used, using a matrix developed by the researchers including the four salutogenic domains and the five levels of the ecological framework.
Ethics and dissemination
Formal ethical approval is not necessary for this scoping review as it does not involve the collection of primary data. The outcomes of this study will be disseminated through peer-reviewed journal articles, conference/seminar presentations, and developed into resources for stakeholders and collaborators.
Trial registration number
Open Science Framework (DOI 10.17605/OSF.IO/CJRUY).
Metadata
| Item Type: | Article |
|---|---|
| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © Author(s) (or their employer(s)) 2026. Re-use permitted under CC BY. Published by BMJ Group. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. https://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Adverse events; Child; MENTAL HEALTH; Humans; Scoping Reviews as Topic; Mental Health; Adult; Protective Factors; Research Design; Child; Adverse Childhood Experiences; Mental Disorders |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Social Sciences (Sheffield) > School of Sociological Studies, Politics and International Relations |
| Date Deposited: | 25 Feb 2026 09:48 |
| Last Modified: | 25 Feb 2026 09:48 |
| Status: | Published |
| Publisher: | BMJ |
| Refereed: | Yes |
| Identification Number: | 10.1136/bmjopen-2025-112097 |
| Related URLs: | |
| Sustainable Development Goals: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:238362 |
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Filename: e112097.full.pdf
Licence: CC-BY 4.0


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