A standardised approach to the pathological dissection and reporting of pelvic exenteration specimens: recommendations from the UK Pelvic Exenteration Network (UKPEN)

Pelvic exenterations are complex operations associated with significant morbidity and resource implications. Resection is undertaken with curative intent and achieving clear margins is paramount to successful oncological outcomes. Comprehensive pathological reporting is essential, yet there are no internationally agreed guidelines describing an optimal approach. This article presents a standardised approach to the pathological dissection and reporting of pelvic exenteration specimens, endorsed by the UK Pelvic Exenteration Network (UKPEN). This includes all relevant steps of the clinical pathway, from acknowledging the importance of pathology involvement in preoperative radiological planning to post-operative correlation meetings. Key recommendations are exemplified with illustrative examples. Standardisation of pelvic exenteration pathology will contribute to optimal patient care, enhance multidisciplinary learning and service development, provide quality assurance and auditable standards, and facilitate national and international research.