Obaida, S.M.B. orcid.org/0000-0002-4713-081X and Harrity, J.P.A. orcid.org/0000-0001-5038-5699 (2025) Base-mediated annulation strategy to naphthol boronic ester derivatives. The Journal of Organic Chemistry, 90 (44). pp. 15867-15870. ISSN: 0022-3263
Abstract
The base-promoted annulation reaction of homophthalic anhydrides with potassium ynone trifluoroborate salts offers a convenient method to access a range of ortho-acylphenol derivatives with complete regiocontrol. The products can be further functionalized chemoselectively by cross-coupling, O-alkylation, and oxidative coupling processes.
Metadata
| Item Type: | Article |
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| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2025 American Chemical Society. This is an author-produced version of a paper subsequently published in The Journal of Organic Chemistry. Uploaded in accordance with the publisher's self-archiving policy. |
| Keywords: | Annulations; Aromatic compounds; Functionalization; Organic compounds; Reaction products |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Mathematical and Physical Sciences The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
| Date Deposited: | 20 Nov 2025 12:01 |
| Last Modified: | 20 Nov 2025 12:01 |
| Status: | Published |
| Publisher: | American Chemical Society (ACS) |
| Refereed: | Yes |
| Identification Number: | 10.1021/acs.joc.5c02223 |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:234730 |
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Filename: Harrity Manuscript.pdf

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