Simpson, E.L. orcid.org/0000-0001-7353-5979, Essat, M., Wong, R. et al. (2 more authors) (2025) Effectiveness of psychosocial interventions for adults with substance use disorder that have a co‐occurring common mental health disorder: an umbrella review. Drug and Alcohol Review. ISSN: 0959-5236
Abstract
Issues
People with substance use disorders can have co-occurring mental disorders.
Approach
An umbrella review was conducted to identify evidence of the effectiveness of psychosocial interventions for adults (aged 18+) with substance use disorders and co-occurring common mental health disorders. Systematic reviews were sought of randomised controlled trials of psychosocial interventions compared to each other, treatment as usual or wait-list. Five databases were systematically searched in February 2024. Data, including critical appraisal (Joanna Briggs Institute Checklist), were extracted by one reviewer and checked by another. Data were discussed in a narrative review.
Key Findings
Of 5420 unique records, 28 systematic reviews were included. The methodological quality of the reviews was good. Most reviews focused on depression, anxiety or post-traumatic stress disorder. There was much heterogeneity between reviews, and randomised controlled trials within reviews. Most of the interventions and many of the treatment-as-usual comparators resulted in significant improvement in substance use and mental health disorders. Results suggested integrated (co-ordinated) treatment for co-occurring diagnosis patients was better than treating one condition alone, and usually better than parallel uncoordinated services. There was limited evidence assessing sequential treatment, but this suggested similar effectiveness to integrated treatment.
Implications
Implications for current practise could not be recommended due to heterogeneity. Improvement shown by all types of psychosocial intervention including active comparators precluded recommending one type of intervention over another.
Conclusion
Further research is needed comparing integrated with parallel or sequential treatment, with follow-up of 6 months or longer, and sample size large enough to encompass dropout.
Metadata
| Item Type: | Article |
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| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2025 The Author(s). This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | mental disorders; psychosocial intervention; substance‐related disorders; systematic review |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
| Date Deposited: | 12 Nov 2025 11:13 |
| Last Modified: | 12 Nov 2025 11:13 |
| Status: | Published online |
| Publisher: | Wiley |
| Refereed: | Yes |
| Identification Number: | 10.1111/dar.70066 |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:234370 |

CORE (COnnecting REpositories)
CORE (COnnecting REpositories)