HU searches and binds specific DNA via a multi-step process combining weak electrostatic binding, protein reorientation and DNA flexibility

Chan, Elliot, LEAKE, MARK CHRISTIAN orcid.org/0000-0002-1715-1249 and NOY, AGNES orcid.org/0000-0003-0673-8949 (2025) HU searches and binds specific DNA via a multi-step process combining weak electrostatic binding, protein reorientation and DNA flexibility. JACS Au. 4870–4878. ISSN: 2691-3704

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Item Type: Article
Authors/Creators:
Copyright, Publisher and Additional Information:

© 2025 The Authors
Dates:
  • Accepted: 8 October 2025
  • Published (online): 14 October 2025
  • Published: 27 October 2025
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
The University of York > Faculty of Sciences (York) > Physics (York)
Funding Information:
Funder
Grant number
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
BB/S506795/1
EPSRC
EP/R51181X/1
Date Deposited: 05 Nov 2025 11:00
Last Modified: 03 Dec 2025 13:00
Published Version: https://doi.org/10.1021/jacsau.5c00800
Status: Published
Refereed: Yes
Identification Number: 10.1021/jacsau.5c00800
Open Archives Initiative ID (OAI ID):

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Description: HU Searches and Binds Specific DNA via a Multistep Process Combining Weak Electrostatic Binding, Protein Reorientation, and DNA Flexibility

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