11β-hydroxysteroid dehydrogenase type 1 within osteoclasts mediates the bone protective properties of therapeutic corticosteroids in chronic inflammation

Fenton, C.G., Crastin, A., Martin, C.S. orcid.org/0000-0002-4428-2658 et al. (13 more authors) (2022) 11β-hydroxysteroid dehydrogenase type 1 within osteoclasts mediates the bone protective properties of therapeutic corticosteroids in chronic inflammation. International Journal of Molecular Sciences, 23 (13). 7334. ISSN: 1661-6596

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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Keywords: 11β-hydroxysteroid dehydrogenase type 1; corticosteroids; inflammatory bone loss; osteoclasts; polyarthritis; rheumatoid arthritis; 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Arthritis, Rheumatoid; Bone Resorption; Corticosterone; Glucocorticoids; Inflammation; Osteoarthritis; Osteoclasts
Dates:
  • Accepted: 29 June 2022
  • Published (online): 30 June 2022
  • Published: 1 July 2022
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Date Deposited: 03 Oct 2025 14:23
Last Modified: 03 Oct 2025 14:23
Status: Published
Publisher: MDPI AG
Refereed: Yes
Identification Number: 10.3390/ijms23137334
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