ATM inhibition increases the anti-tumor efficacy of radium-223 (Ra-223) against prostate cancer bone metastasis in preclinical models

Lefley, D.V., Jones, C.G. orcid.org/0000-0003-2958-8322, Zhou, J. et al. (5 more authors) (2025) ATM inhibition increases the anti-tumor efficacy of radium-223 (Ra-223) against prostate cancer bone metastasis in preclinical models. JBMR Plus, 9 (10). ziaf129. ISSN: 2473-4039

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Item Type: Article
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© The Author(s) 2025. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: prostate cancer; bone metastasis; ATM inhibition; Ra-223; radiosensitization
Dates:
  • Submitted: 11 March 2025
  • Accepted: 28 July 2025
  • Published (online): 5 August 2025
  • Published: 10 October 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Depositing User: Symplectic Sheffield
Date Deposited: 26 Sep 2025 09:55
Last Modified: 26 Sep 2025 09:55
Status: Published
Publisher: Oxford University Press (OUP)
Refereed: Yes
Identification Number: 10.1093/jbmrpl/ziaf129
Open Archives Initiative ID (OAI ID):

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