Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells

Lu, H., Goh, K.J., Tan, E.K. et al. (10 more authors) (2025) Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells. Cell Reports, 44 (10). 116321. ISSN: 2211-1247

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Item Type: Article
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Copyright, Publisher and Additional Information:

© 2025 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Keywords: multiciliated cells; centrioles; de novo centriole biogenesis; MCIDAS; E2F4; E2F5; human embryonic stem cells; mouse tracheal epithelial cells; ependymal cells; primary ciliary dyskinesia
Dates:
  • Accepted: 29 August 2025
  • Published (online): 19 September 2025
  • Published: 28 October 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Depositing User: Symplectic Sheffield
Date Deposited: 23 Sep 2025 15:27
Last Modified: 24 Sep 2025 00:42
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.celrep.2025.116321
Open Archives Initiative ID (OAI ID):

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