Makris, M. orcid.org/0000-0001-7622-7939 (2025) PF4-associated immune thrombocytopenia and thrombosis (PITT)—More than heparin and vaccines. British Journal of Haematology. ISSN 0007-1048
Abstract
A young woman presented with portal vein thrombosis and thrombocytopenia and developed further extensive thrombosis following treatment with heparin. Despite no previous heparin exposure, she was found to be strongly positive for anti-platelet factor 4 (PF4) antibodies. She had acute cytomegalovirus (CMV) infection and a monoclonal gammopathy.
Commentary on: Nicolson et al. Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics. Br J Haematol 2025 (Online ahead of print). doi: 10.1111/bjh.20092.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2025 The Author(s). British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/ |
Keywords: | Biomedical and Clinical Sciences; Immunology; Hematology; Infection |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection, Immunity and Cardiovascular Disease |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 08 May 2025 13:44 |
Last Modified: | 08 May 2025 13:44 |
Status: | Published online |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1111/bjh.20125 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:226330 |