Using insect larvae and their microbiota for plastic degradation

Plastic pollution is one of the biggest current global threats to the environment given that petroleum-based plastic is recalcitrant and can stay in the environment for decades, even centuries, depending on the specific plastic type. Since less than 10% of all plastic made is recycled, and the other solutions (such as incineration or landfill storage) are pollutant methods, new, environmentally friendly solutions are needed. In this regard, the latest biotechnological discovery on this topic is the capability of insect larvae to use plastic polymers as carbon feedstock. This present review describes the most relevant information on the insect larvae capable of degrading plastic, mainly Galleria mellonella (Fabricius, 1798), Tenebrio molitor (Linnaeus, 1758), and Zophobas atratus (Fabricius, 1776), and also adds new information about other less commonly studied “plastivore” insects such as termites. This review covers the literature from the very first work describing plastic degradation by larvae published in 2014 all the way to the very latest research available (till June 2024), focusing on the identification of a wide variety of plastic-degrading microorganisms isolated from larvae guts and on the understanding of the potential molecular mechanisms present for degradation to take place. It also describes the latest discoveries, which include the identification of novel enzymes from waxworm saliva.