van Oppen, J.D. orcid.org/0000-0002-2570-7112, Patel, N. and Tarique, A. (2020) Hyperkinetic reaction to dihydrocodeine. BMJ Case Reports, 13 (1). e233264. ISSN 1757-790X
Abstract
A young man was using dihydrocodeine analgesia for ear pain having had suppurative otitis media. He attended the emergency department with restlessness and twitching movements in his arms and legs. He had fever with otherwise normal vital signs. He had no signs of cerebellar pathology. Investigations were normal. The working diagnosis was of hyperkinetic reaction to dihydrocodeine. Symptoms resolved within 48 hours of withdrawing the drug. Serotonin toxicity is a rare side effect of dihydrocodeine. There is a theoretical basis for increased side effects when taken with cannabidiol- based substances.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 BMJ Publishing Group Limited. This article has been accepted for publication in BMJ Case Reports, 2020, following peer review, and the Version of Record can be accessed online at http://dx.doi.org/10.1136/10.1136/bcr-2019-233264. |
Keywords: | drug interactions; emergency medicine; movement disorders (other than Parkinsons); neurology (drugs and medicines); unwanted effects / adverse reactions; Adult; Analgesics, Opioid; Codeine; Diagnosis, Differential; Humans; Hyperkinesis; Male; Otitis Media; Serotonin Syndrome |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 23 Jan 2024 10:06 |
Last Modified: | 24 Jan 2024 09:19 |
Status: | Published |
Publisher: | BMJ |
Refereed: | Yes |
Identification Number: | 10.1136/bcr-2019-233264 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:207954 |