Abadi, E, Segars, WP, Tsui, BMW et al. (6 more authors) (2020) Virtual clinical trials in medical imaging: a review. Journal of Medical Imaging, 7 (04). 042805. 042805-. ISSN 2329-4302
Abstract
The accelerating complexity and variety of medical imaging devices and methods have outpaced the ability to evaluate and optimize their design and clinical use. This is a significant and increasing challenge for both scientific investigations and clinical applications. Evaluations would ideally be done using clinical imaging trials. These experiments, however, are often not practical due to ethical limitations, expense, time requirements, or lack of ground truth. Virtual clinical trials (VCTs) (also known as in silico imaging trials or virtual imaging trials) offer an alternative means to efficiently evaluate medical imaging technologies virtually. They do so by simulating the patients, imaging systems, and interpreters. The field of VCTs has been constantly advanced over the past decades in multiple areas. We summarize the major developments and current status of the field of VCTs in medical imaging. We review the core components of a VCT: computational phantoms, simulators of different imaging modalities, and interpretation models. We also highlight some of the applications of VCTs across various imaging modalities.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 Society of Photo-Optical Instrumentation Engineers (SPIE). Reproduced in accordance with the publisher's self-archiving policy. |
Keywords: | virtual clinical trials; virtual imaging trials; computational phantoms; simulations; medical imaging simulation; in silico imaging |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Computing (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 13 May 2020 15:11 |
Last Modified: | 25 Jun 2023 22:15 |
Status: | Published |
Publisher: | Society of Photo-optical Instrumentation Engineers |
Identification Number: | 10.1117/1.jmi.7.4.042805 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:160600 |