Maiti, R., Duan, M.Q., Danby, S. orcid.org/0000-0001-7363-140X et al. (3 more authors) (2020) Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography. Journal of the Mechanical Behavior of Biomedical Materials, 102. 103501. ISSN 1751-6161
Abstract
Background
Changes in body posture cause changes in morphological properties at different skin sites. Although previous studies have reported the thickness of the skin, the details of the postures are not generally given. This paper presents the effect of a change in posture on parameters such as thickness and surface roughness in 21 load-bearing and non-load-bearing sites.
Materials and methods
A total of 12 volunteers (8 males and 4 females) were selected in an age group of 18–35 years and of Fitzpatrick skin type I-III. Images were captured using a clinically-approved VivoSight® optical coherence tomography system and analysed using an algorithm provided by Michelson Diagnostics.
Results
Overextension (extending joints to full capacity) resulted in changes to thickness, roughness and undulation of the skin around the body.
Discussion and conclusion
The load-bearing regions have thicker skin compared to non-load-bearing sites. This is the first time that undulation topography of the stratum corneum–stratum lucidum and the dermal–epidermal junction layers have been measured and reported using statistical values such as Ra. The data presented could help to define new skin layer models and to determine the variability of the skin around the body and between participants.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
Keywords: | OCT; Stratum corneum; Epidermis; Roughness; Thickness; Undulation |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Mechanical Engineering (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Funding Information: | Funder Grant number Engineering and Physical Science Research Council (EPSRC) EP/K009699/1 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 30 Oct 2019 12:34 |
Last Modified: | 11 Jun 2020 13:22 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.jmbbm.2019.103501 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:152859 |