Colucci, F, McKeegan, P orcid.org/0000-0002-5318-2317, Picton, HM et al. (1 more author) (2018) Mouse embryo assay to evaluate polydimethylsiloxane (PDMS) embryo-toxicity. In: Proceedings of the 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2018). 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2018), 18-21 Jul 2018, Honolulu, HI, USA. IEEE , pp. 4484-4487. ISBN 978-1-5386-3646-6
Abstract
In vitro embryo culture to support In Vitro Fertilization (IVF) procedures is a well-established but still critical technique. In the last decade first attempts to use microfluidic devices in IVF have shown positive results, enabling to control the culture conditions and to preserve the quality of the embryos during their development. In this study we completed an industry standard mouse embryo assay (MEA) to exclude potential toxic effects of PDMS.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 Crown. This is an author produced version of a paper published in Proceedings of the 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2018). Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Embryo; Microfluidics; Mice; Standards; In vitro; Subspace constraints; Oils |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds) |
Funding Information: | Funder Grant number NC3Rs CRACKITEA-SP-3 EU - European Union 748903 |
Depositing User: | Symplectic Publications |
Date Deposited: | 20 Apr 2018 13:57 |
Last Modified: | 17 Jan 2019 15:58 |
Status: | Published |
Publisher: | IEEE |
Identification Number: | 10.1109/EMBC.2018.8513167 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:129871 |