Kakaawla, T.K.K. and Harrity, J.P.A. orcid.org/0000-0001-5038-5699 (2018) Development of an amine-catalyzed regioselective synthesis of pyrroles. Organic Letters, 20 (1). pp. 201-203. ISSN 1523-7060
Abstract
A regioselective synthesis of pyrroles has been devised through the cycloaddition of 1,3-oxazolium-5-olates and enamines. Product regiochemistry is controlled by the enamine substitution pattern. Moreover, an amine-catalyzed variant of this reaction allows aldehydes to be used directly as substrates for pyrrole synthesis.
Metadata
| Item Type: | Article | 
|---|---|
| Authors/Creators: | 
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| Copyright, Publisher and Additional Information: | © 2017 American Chemical Society. This is an author produced version of a paper subsequently published in Organic Letters. Uploaded in accordance with the publisher's self-archiving policy. | 
| Dates: | 
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| Institution: | The University of Sheffield | 
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) | 
| Depositing User: | Symplectic Sheffield | 
| Date Deposited: | 04 Jan 2018 11:09 | 
| Last Modified: | 15 Jul 2020 10:21 | 
| Status: | Published | 
| Publisher: | American Chemical Society | 
| Refereed: | Yes | 
| Identification Number: | 10.1021/acs.orglett.7b03658 | 
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:125781 | 

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