Chemical generation and modification of peptides containing multiple dehydroalanines
Morrison, PM, Foley, PJ, Warriner, SL et al. (1 more author)
(2015)
Chemical generation and modification of peptides containing multiple dehydroalanines.
Chemical Communications, 51 (70).
pp. 13470-13473.
ISSN 1359-7345
Abstract
Chemical formation of dehydroalanine has been widely used for the post-translational modification of protein and peptides, however methods to incorporate multiple dehydroalanine residues into a single peptide have not been defined. We report the use of methyl 2,5-dibromovalerate which can be used to cleanly carry out this transformation.
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)