Webb, NJ, Marsden, SP orcid.org/0000-0002-2723-8954 and Raw, SA (2014) Rhodium(III)-Catalyzed C-H Activation/Annulation with Vinyl Esters as an Acetylene Equivalent. Organic Letters, 16 (18). pp. 4718-4721. ISSN 1523-7060
Abstract
The behavior of electron-rich alkenes in rhodium-catalyzed C–H activation/annulation reactions is investigated. Vinyl acetate emerges as a convenient acetylene equivalent, facilitating the synthesis of sixteen 3,4-unsubstituted isoquinolones, as well as select heteroaryl-fused pyridones. The complementary regiochemical preferences of enol ethers versus enol esters/enamides is discussed
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2014, ACS. This is an author produced version of a paper published in Organic Letters. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 15 Jan 2015 12:54 |
Last Modified: | 14 May 2019 10:29 |
Published Version: | http://dx.doi.org/10.1021/ol502095z |
Status: | Published |
Publisher: | American Chemical Society |
Identification Number: | 10.1021/ol502095z |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:82343 |