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Ahmad, R. and Bath, P.A. (2004) The use of Cox regression and genetic algorithm (CoRGA) for identifying risk factors for mortality in older people. Health Informatics Journal, 10. 221 - 236.
Abstract
The increase in the proportion and number of older people in developed countries has resulted in research investigating risk factors for adverse health outcomes, including mortality. However, research has been limited by the range of risk factors included in regression models. This is partly because traditional statistical methods and software packages allow a restricted number of variables and combinations of variables. This article describes ongoing research to overcome these limitations through the CoRGA program, which combines Cox regression with a genetic algorithm for the variable selection process. CoRGA was used to try and identify the best combination of risk factors for 4-year all-cause mortality. The combination of 10 risk factors identified by CoRGA included both known and new risk factors for mortality in older people. Further research is seeking to develop the program further and to identify further risk factors for all-cause mortality in older people.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2004 SAGE. This is an author produced version of a paper subsequently published in Health Informatics Journal. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Cox regression; Genetic algorithm; Mortality; Risk factors; software package. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Social Sciences (Sheffield) > Information School (Sheffield) |
Depositing User: | Information Studies |
Date Deposited: | 25 Apr 2014 14:22 |
Last Modified: | 25 Apr 2014 14:22 |
Published Version: | http://dx.doi.org/10.1177/1460458204042236 |
Status: | Published |
Publisher: | SAGE Publications |
Refereed: | Yes |
Identification Number: | 10.1177/1460458204042236 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:78629 |
Available Versions of this Item
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The use of Cox regression and genetic algorithm (CoRGA) for identifying risk factors for mortality in older people. (deposited 14 Aug 2009 13:55)
- The use of Cox regression and genetic algorithm (CoRGA) for identifying risk factors for mortality in older people. (deposited 25 Apr 2014 14:22) [Currently Displayed]