Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance

Metadata

Item Type:	Article
Authors/Creators:	Galley, N.F. Greetham, D. Alamán-Zárate, M.G. Williamson, M.P. Evans, C.A. Spittal, W.D. Buddle, J.E. Freeman, J. https://orcid.org/0000-0001-9580-4586 Davis, G.L. https://orcid.org/0000-0002-2826-0897 Dickman, M.J. Wilcox, M.H. https://orcid.org/0000-0002-4565-2868 Lovering, A.L. Fagan, R.P. Mesnage, S.
Copyright, Publisher and Additional Information:	© 2023 THE AUTHORS. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords:	Clostridioides difficile, peptidoglycan, L,D-transpeptidase, cross-link, bacterial cell envelope, antibiotics, beta-lactams
Dates:	Accepted: 27 November 2023 Published (online): 1 December 2023 Published: January 2024
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Medical Research (LIMR) > Division of Gastroenterology and Surgery The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) > FSN Colloids and Food Processing (Leeds)
Date Deposited:	16 Jul 2026 13:33
Last Modified:	16 Jul 2026 13:35
Published Version:	https://www.sciencedirect.com/science/article/pii/...
Status:	Published
Publisher:	Elsevier
Identification Number:	10.1016/j.jbc.2023.105529
Related URLs:	Author
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Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:242461

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