Nested resolution mesh-graph CNN for automated extraction of liver surface anatomical landmarks

The anatomical landmarks on the liver (mesh) surface, including the falciform ligament and liver ridge, are composed of triangular meshes of varying shapes, sizes, and positions, making them highly complex. Extracting and segmenting these landmarks is critical for augmented reality-based intraoperative navigation and monitoring. The key to this task lies in comprehensively understanding the overall geometric shape and local topological information of the liver mesh. However, due to the liver’s variations in shape and appearance, coupled with limited data, deep learning methods often struggle with automatic liver landmark segmentation. To address this, we propose a two-stage automatic framework combining mesh-CNN and graph-CNN. In the first stage, dynamic graph convolution (DGCNN) is employed on low-resolution meshes to achieve rapid global understanding, generating initial landmark proposals at two levels, “dilation” and “erosion”, and mapping them onto the original high-resolution surface. Subsequently, a refinement network based on mesh convolution fuses these landmark proposals from edge features along the local topology of the high-resolution mesh surface, producing refined segmentation results. Additionally, we incorporate an anatomy-aware Dice loss to address resolution imbalance and better handle sparse anatomical regions. Extensive experiments on two liver datasets, both in-distribution and out-of-distribution, demonstrate that our method accurately processes liver meshes of different resolutions, outperforming state-of-the-art methods. The reconstructed liver mesh dataset and the source code are available at https://github.com/xukun-zhang/MeshGraphCNN.