Nail, V., Tarn, M.D. orcid.org/0000-0001-5827-4125, He, P. et al. (2 more authors) (2021) Developing the future of clinical radiopharmacy: Optimising on-chip gallium-68 radiolabelling for pet imaging. In: Proceedings of 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020). 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020), 04-09 Oct 2020, Virtual. Chemical and Biological Microsystems Society (CBMS), pp. 715-716. ISBN: 978-1-7334190-1-7.
Abstract
Positron emission tomography (PET) imaging is a growing area with major interest in radiometal labelling and dose-on-demand supply. However, current production methods do not match effectively with these requirements. Microreactor technology is a promising candidate as a future standard radiosynthesis tool. The fluid transport is commonly achieved using syringe pump, but it cannot handle different processes alongside. Herein, we describe an alternative fluid transport mechanism for gallium-68 radiolabelling via peristaltic pump. The optimisation of this reaction yielded a two-fold decrease in the required quantity of chelator after 4 min of reaction at room temperature.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Keywords: | positron emission tomography, PET, molecular imaging, radiolabelling, synthetic chemistry |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Earth and Environment (Leeds) |
Date Deposited: | 02 Oct 2025 13:36 |
Last Modified: | 02 Oct 2025 13:36 |
Published Version: | https://www.proceedings.com/57064.html |
Status: | Published |
Publisher: | Chemical and Biological Microsystems Society (CBMS) |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:232181 |