Mapping the natural history of amyotrophic lateral sclerosis: time-to-event analysis of clinical milestones in the pan-European, population-based PRECISION-ALS cohort

Caravaca Puchades, A., McDonough, H.E., Al-Chalabi, A. et al. (26 more authors) (2025) Mapping the natural history of amyotrophic lateral sclerosis: time-to-event analysis of clinical milestones in the pan-European, population-based PRECISION-ALS cohort. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 26 (sup1). pp. 8-19. ISSN 2167-8421

Abstract

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Item Type: Article
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Copyright, Publisher and Additional Information:

© 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

Keywords: Time-to-event; survival analysis; clinical milestones; disease trajectory; disease progression
Dates:
  • Accepted: 7 December 2024
  • Published (online): 6 May 2025
  • Published: 15 May 2025
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Funding Information:
Funder
Grant number
Economic and Social Research Council
ES/L008238/1
National Institute for Health and Care Research
IS-BRC-1215-20017
DEPARTMENT OF HEALTH AND SOCIAL CARE
NIHR301648
Medical Research Council
MR/L501529/1
Depositing User: Symplectic Sheffield
Date Deposited: 21 May 2025 10:53
Last Modified: 21 May 2025 10:53
Status: Published
Publisher: Informa UK Limited
Refereed: Yes
Identification Number: 10.1080/21678421.2024.2448535
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