Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling

Hobor, S., Al Bakir, M. orcid.org/0000-0002-0846-8332, Hiley, C.T. et al. (292 more authors) (2024) Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature Communications, 15. 4871. ISSN 2041-1723

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Item Type: Article
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© 2024 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords: Humans; Tumor Suppressor Protein p53; Animals; Chromosomal Instability; Mice; Lung Neoplasms; ErbB Receptors; Mutation; Drug Resistance, Neoplasm; Cell Line, Tumor; Protein Kinase Inhibitors; Adenocarcinoma of Lung; Molecular Targeted Therapy; Female; DNA Copy Number Variations; Male
Dates:
  • Published: 13 June 2024
  • Published (online): 13 June 2024
  • Accepted: 28 March 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine and Population Health
Depositing User: Symplectic Sheffield
Date Deposited: 28 Jan 2025 16:02
Last Modified: 28 Jan 2025 16:02
Published Version: https://doi.org/10.1038/s41467-024-47606-9
Status: Published
Publisher: Springer Science and Business Media LLC
Refereed: Yes
Identification Number: 10.1038/s41467-024-47606-9
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