An interaction-based mixing model for predicting porosity and tensile strength of directly compressed ternary blends of pharmaceutical powders

Corrigan, J. orcid.org/0000-0002-5238-5577, Li, F., Dawson, N. et al. (4 more authors) (2024) An interaction-based mixing model for predicting porosity and tensile strength of directly compressed ternary blends of pharmaceutical powders. International Journal of Pharmaceutics, 664. 124587. ISSN 0378-5173

Abstract

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Item Type: Article
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© 2024 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Keywords: Compactability; Compressibility; Direct compression; Formulation design; Modeling; Tensile Strength; Powders; Tensile Strength; Ibuprofen; Acetaminophen; Lactose; Porosity; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Models, Theoretical
Dates:
  • Published: 25 October 2024
  • Published (online): 13 August 2024
  • Accepted: 12 August 2024
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > School of Chemical, Materials and Biological Engineering
The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Chemical and Biological Engineering (Sheffield)
Funding Information:
Funder
Grant number
INNOVATE UK
TS/T011270/1 41299
Depositing User: Symplectic Sheffield
Date Deposited: 05 Feb 2025 10:07
Last Modified: 05 Feb 2025 10:07
Status: Published
Publisher: Elsevier BV
Refereed: Yes
Identification Number: 10.1016/j.ijpharm.2024.124587
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