Batchelor, DVB orcid.org/0000-0001-6489-9578, Armistead, FJ orcid.org/0000-0003-1274-5379, Ingram, N orcid.org/0000-0001-5274-8502 et al. (4 more authors) (2021) Nanobubbles for therapeutic delivery: Production, stability and current prospects. Current Opinion in Colloid & Interface Science, 54. 101456. ISSN 1359-0294
Abstract
Nanobubbles (NBs) have recently garnered widespread attention for their potential use as dual diagnostic and therapeutic agents. Similar to their micron-sized relatives (microbubbles), NBs are shell-stabilized, gas-cored bubbles that in conjunction with ultrasound can be used to increase imaging contrast, as well as provide a mechanism for trigger drug release and increased therapeutic delivery.
In this review, we specifically focus on their development as agents to enhance drug delivery, discussing theory, characterization techniques, key formulations and prospects for translation into clinical use.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | Nanobubbles; Ultrafine bubbles; Ultrasound; Triggered release; Drug delivery; Therapeutic; Theranostic; Chemotherapy; Cancer; Biomedical |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Robotics, Autonomous Systems & Sensing (Leeds) The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Physics and Astronomy (Leeds) > Molecular & Nanoscale Physics |
Funding Information: | Funder Grant number EPSRC (Engineering and Physical Sciences Research Council) EP/P023266/1 |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 Aug 2022 15:27 |
Last Modified: | 04 Aug 2022 15:27 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.cocis.2021.101456 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:189597 |